Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000104228 Gene ID 23087 Accession 16285
Symbol TRIM35 Alias HLS5;MAIR Full Name tripartite motif containing 35
Status Confidence Length 26387 bases Strand Minus strand
Position 8 : 27284886 - 27311272 RNA binding domain SPRY
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000301924 SPRY PF00622 6.8e-10 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
TRIM35-201 ENST00000305364 4183 493aa ENSP00000301924
TRIM35-204 ENST00000521283 619 100aa ENSP00000429356
TRIM35-203 ENST00000521253 1215 266aa ENSP00000428770
TRIM35-202 ENST00000519219 423 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003674enables molecular_function1NDHomo_sapiens(9606)Function
GO:0005634located_in nucleus1ISSHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,ISSHomo_sapiens(9606)Component
GO:0006915involved_in apoptotic process1IEAHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0016567involved_in protein ubiquitination2IBA,IEAHomo_sapiens(9606)Process
GO:0043065involved_in positive regulation of apoptotic process2IBA,IDAHomo_sapiens(9606)Process
GO:0044790involved_in suppression of viral release by host1IDAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response2IBA,IDAHomo_sapiens(9606)Process
GO:0045930involved_in negative regulation of mitotic cell cycle1IDAHomo_sapiens(9606)Process
GO:0061630enables ubiquitin protein ligase activity1IBAHomo_sapiens(9606)Function

Expression