RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	Stress granucleNucleoli
BulkPerturb-seq

Ensembl ID	ENSG00000103275	Gene ID	7329	Accession	12485
Symbol	UBE2I	Alias	P18;UBC9;C358B7.1	Full Name	ubiquitin conjugating enzyme E2 I
Status	Confidence	Length	18139 bases	Strand	Plus strand
Position	16 : 1308880 - 1327018	RNA binding domain	N.A.
Summary	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
UBE2I-202	ENST00000355803	3253	158aa	ENSP00000348056
UBE2I-201	ENST00000325437	2832	158aa	ENSP00000324897
UBE2I-204	ENST00000397515	3109	158aa	ENSP00000380650
UBE2I-208	ENST00000473256	1771	No protein	-
UBE2I-203	ENST00000397514	2850	158aa	ENSP00000380649
UBE2I-218	ENST00000568288	501	No protein	-
UBE2I-216	ENST00000567383	3151	158aa	ENSP00000456188
UBE2I-206	ENST00000403747	1217	158aa	ENSP00000385009
UBE2I-217	ENST00000568209	266	No protein	-
UBE2I-210	ENST00000562482	735	No protein	-
UBE2I-222	ENST00000678584	718	No protein	-
UBE2I-213	ENST00000566587	1098	158aa	ENSP00000457064
UBE2I-207	ENST00000406620	3509	158aa	ENSP00000384568
UBE2I-209	ENST00000562470	3131	158aa	ENSP00000490882
UBE2I-223	ENST00000679082	1983	No protein	-
UBE2I-215	ENST00000567074	3123	158aa	ENSP00000455893
UBE2I-205	ENST00000402301	1708	184aa	ENSP00000384361
UBE2I-214	ENST00000566775	410	74aa	ENSP00000455252
UBE2I-220	ENST00000677314	3124	74aa	ENSP00000503670
UBE2I-212	ENST00000566159	2642	No protein	-
UBE2I-211	ENST00000564143	444	No protein	-
UBE2I-224	ENST00000679137	2737	No protein	-
UBE2I-221	ENST00000677987	5436	No protein	-
UBE2I-219	ENST00000568989	3766	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
47576	Intelligence Tests	3.4072500E-005	-
47948	Child Development Disorders, Pervasive	1.6251000E-005	-
48191	Child Development Disorders, Pervasive	6.9944000E-006	-
48978	Child Development Disorders, Pervasive	1.5126000E-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000122	involved_in negative regulation of transcription by RNA polymerase II	2	IMP,TAS	Homo_sapiens(9606)	Process
GO:0000795	located_in synaptonemal complex	1	TAS	Homo_sapiens(9606)	Component
GO:0001221	enables transcription coregulator binding	1	IPI	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	3	HDA,IBA,IDA	Homo_sapiens(9606)	Component
GO:0005635	located_in nuclear envelope	1	TAS	Homo_sapiens(9606)	Component
GO:0005643	part_of nuclear pore	1	NAS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0006511	involved_in ubiquitin-dependent protein catabolic process	1	TAS	Homo_sapiens(9606)	Process
GO:0007059	involved_in chromosome segregation	1	IEA	Homo_sapiens(9606)	Process
GO:0007084	involved_in mitotic nuclear membrane reassembly	1	TAS	Homo_sapiens(9606)	Process
GO:0008134	enables transcription factor binding	1	IPI	Homo_sapiens(9606)	Function
GO:0016605	located_in PML body	1	IDA	Homo_sapiens(9606)	Component
GO:0016925	involved_in protein sumoylation	5	IBA,IDA,IEA,IMP,TAS	Homo_sapiens(9606)	Process
GO:0019789	enables SUMO transferase activity	2	EXP,TAS	Homo_sapiens(9606)	Function
GO:0019899	enables enzyme binding	1	IPI	Homo_sapiens(9606)	Function
GO:0030335	involved_in positive regulation of cell migration	1	IMP	Homo_sapiens(9606)	Process
GO:0036211	involved_in protein modification process	1	TAS	Homo_sapiens(9606)	Process
GO:0043123	involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling	1	IEA	Homo_sapiens(9606)	Process
GO:0043398	enables HLH domain binding	1	IEA	Homo_sapiens(9606)	Function
GO:0044388	enables small protein activating enzyme binding	1	IPI	Homo_sapiens(9606)	Function
GO:0045892	involved_in negative regulation of DNA-templated transcription	1	IDA	Homo_sapiens(9606)	Process
GO:0048471	located_in perinuclear region of cytoplasm	1	IEA	Homo_sapiens(9606)	Component
GO:0051168	involved_in nuclear export	1	EXP	Homo_sapiens(9606)	Process
GO:0051301	involved_in cell division	1	IEA	Homo_sapiens(9606)	Process
GO:0061656	enables SUMO conjugating enzyme activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0071535	enables RING-like zinc finger domain binding	1	IPI	Homo_sapiens(9606)	Function
GO:0106068	part_of SUMO ligase complex	1	IPI	Homo_sapiens(9606)	Component
GO:1903755	involved_in positive regulation of SUMO transferase activity	1	IDA	Homo_sapiens(9606)	Process
GO:1990234	part_of transferase complex	1	IDA	Homo_sapiens(9606)	Component