Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligase
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000103152 Gene ID 4350 Accession 7211
Symbol MPG Alias AAG;MDG;ADPG;APNG;Mid1;anpg;PIG11;PIG16;CRA36.1 Full Name N-methylpurine DNA glycosylase
Status Confidence Length 8845 bases Strand Plus strand
Position 16 : 77007 - 85851 RNA binding domain N.A.
Summary Predicted to enable alkylbase DNA N-glycosylase activity. Predicted to be involved in base-excision repair. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
32788345 RNA abasic sites in yeast and human cells. Yaojuan Liu 2020-08-25 Proceedings of the National Academy of Sciences of the United States of America

Transcripts

Name Transcript ID bp Protein Translation ID
MPG-204 ENST00000436333 884 251aa ENSP00000388097
MPG-203 ENST00000397817 1039 281aa ENSP00000380918
MPG-202 ENST00000356432 1036 293aa ENSP00000348809
MPG-205 ENST00000475280 510 No protein -
MPG-201 ENST00000219431 1193 298aa ENSP00000219431

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003684enables damaged DNA binding1TASHomo_sapiens(9606)Function
GO:0003905enables alkylbase DNA N-glycosylase activity1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006284involved_in base-excision repair1IBAHomo_sapiens(9606)Process
GO:0006307involved_in DNA dealkylation involved in DNA repair1TASHomo_sapiens(9606)Process
GO:0008725enables DNA-3-methyladenine glycosylase activity1IEAHomo_sapiens(9606)Function
GO:0019104enables DNA N-glycosylase activity1TASHomo_sapiens(9606)Function
GO:0042645located_in mitochondrial nucleoid1IEAHomo_sapiens(9606)Component
GO:0043916enables DNA-7-methylguanine glycosylase activity1IEAHomo_sapiens(9606)Function
GO:0045007involved_in depurination1TASHomo_sapiens(9606)Process
GO:0052821enables DNA-7-methyladenine glycosylase activity1IEAHomo_sapiens(9606)Function
GO:0052822enables DNA-3-methylguanine glycosylase activity1IEAHomo_sapiens(9606)Function

Expression