Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000100461 Gene ID 55147 Accession 20155
Symbol RBM23 Alias PP239;RNPC4;CAPERbeta Full Name RNA binding motif protein 23
Status Confidence Length 25979 bases Strand Minus strand
Position 14 : 22893204 - 22919182 RNA binding domain RRM_1 , RBM39linker
Summary This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It is also implicated in the steroid receptor-dependent regulation of alternative splicing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000382806 RRM_1 PF00076 2.1e-34 1
ENSP00000382806 RRM_1 PF00076 2.1e-34 2
ENSP00000382806 RBM39linker PF15519 2.3e-11 3
ENSP00000339220 RRM_1 PF00076 2.1e-34 1
ENSP00000339220 RRM_1 PF00076 2.1e-34 2
ENSP00000339220 RBM39linker PF15519 2.1e-11 3
ENSP00000352956 RRM_1 PF00076 2.3e-34 1
ENSP00000352956 RRM_1 PF00076 2.3e-34 2
ENSP00000352956 RBM39linker PF15519 2.3e-11 3
ENSP00000438504 RRM_1 PF00076 2.3e-34 1
ENSP00000438504 RRM_1 PF00076 2.3e-34 2
ENSP00000438504 RBM39linker PF15519 1.1e-11 3
ENSP00000452602 RRM_1 PF00076 1.3e-22 1
ENSP00000452602 RBM39linker PF15519 4.6e-12 2
ENSP00000451642 RRM_1 PF00076 1.7e-22 1
ENSP00000451642 RBM39linker PF15519 5.5e-12 2
ENSP00000452171 RRM_1 PF00076 9.7e-14 1
ENSP00000450556 RRM_1 PF00076 2e-09 1
ENSP00000451838 RBM39linker PF15519 1.5e-12 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
35198010 Circular RNA as a Potential Biomarker for Forensic Age Prediction. Junyan Wang 2022-01-01 Frontiers in genetics

Transcripts

Name Transcript ID bp Protein Translation ID
RBM23-203 ENST00000359890 10007 439aa ENSP00000352956
RBM23-215 ENST00000555209 2278 189aa ENSP00000452602
RBM23-233 ENST00000557667 4240 No protein -
RBM23-204 ENST00000399922 2430 423aa ENSP00000382806
RBM23-202 ENST00000346528 2361 405aa ENSP00000339220
RBM23-205 ENST00000542016 1743 269aa ENSP00000438504
RBM23-209 ENST00000553884 808 214aa ENSP00000451642
RBM23-223 ENST00000556838 590 No protein -
RBM23-228 ENST00000557245 387 82aa ENSP00000451838
RBM23-226 ENST00000557127 472 No protein -
RBM23-201 ENST00000307814 2320 No protein -
RBM23-220 ENST00000556186 603 No protein -
RBM23-229 ENST00000557403 826 114aa ENSP00000452171
RBM23-206 ENST00000553738 619 No protein -
RBM23-219 ENST00000555722 602 50aa ENSP00000450556
RBM23-211 ENST00000553920 556 No protein -
RBM23-227 ENST00000557227 552 21aa ENSP00000450423
RBM23-218 ENST00000555714 561 No protein -
RBM23-212 ENST00000554256 581 144aa ENSP00000452583
RBM23-222 ENST00000556687 1124 No protein -
RBM23-210 ENST00000553902 581 No protein -
RBM23-214 ENST00000554955 690 No protein -
RBM23-225 ENST00000556984 575 No protein -
RBM23-231 ENST00000557549 582 101aa ENSP00000450558
RBM23-216 ENST00000555676 583 100aa ENSP00000451364
RBM23-232 ENST00000557571 573 91aa ENSP00000452382
RBM23-224 ENST00000556862 569 92aa ENSP00000452557
RBM23-230 ENST00000557464 457 66aa ENSP00000451403
RBM23-213 ENST00000554618 588 75aa ENSP00000451448
RBM23-221 ENST00000556365 549 No protein -
RBM23-208 ENST00000553876 267 59aa ENSP00000450672
RBM23-217 ENST00000555691 571 57aa ENSP00000452538
RBM23-207 ENST00000553777 328 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
104780Education9E-1327225129

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000100461homo_sapiensENSP0000029597117.70669.10624homo_sapiensENSP0000035295623.91812.3007
ENSG00000100461homo_sapiensENSP0000030413914.03068.67347homo_sapiensENSP0000035295612.52857.74487
ENSG00000100461homo_sapiensENSP000004174514.592312.7179homo_sapiensENSP0000035295611.16176.60592
ENSG00000100461homo_sapiensENSP0000047869124.340213.783homo_sapiensENSP0000035295618.906610.7062
ENSG00000100461homo_sapiensENSP0000044536621.246513.5977homo_sapiensENSP0000035295617.084310.9339
ENSG00000100461homo_sapiensENSP0000034182625.268814.5161homo_sapiensENSP0000035295621.412312.3007
ENSG00000100461homo_sapiensENSP0000035009028.12516.5625homo_sapiensENSP0000035295620.501112.0729
ENSG00000100461homo_sapiensENSP0000049380529.062516.5625homo_sapiensENSP0000035295621.184512.0729
ENSG00000100461homo_sapiensENSP0000037630924.338613.7566homo_sapiensENSP0000035295620.956711.8451
ENSG00000100461homo_sapiensENSP0000028407322.865914.6341homo_sapiensENSP0000035295617.084310.9339
ENSG00000100461homo_sapiensENSP0000031047126.740916.9916homo_sapiensENSP0000035295621.867913.8952
ENSG00000100461homo_sapiensENSP0000030916626.923117.033homo_sapiensENSP0000035295622.323514.123
ENSG00000100461homo_sapiensENSP0000049824815.38468.71795homo_sapiensENSP0000035295613.66747.74487
ENSG00000100461homo_sapiensENSP0000035964515.85689.20716homo_sapiensENSP0000035295614.1238.20046
ENSG00000100461homo_sapiensENSP0000040137124.611414.2487homo_sapiensENSP0000035295621.640112.5285
ENSG00000100461homo_sapiensENSP0000025755222.375714.3646homo_sapiensENSP0000035295618.45111.8451
ENSG00000100461homo_sapiensENSP0000028172220.262710.3189homo_sapiensENSP0000035295624.601412.5285
ENSG00000100461homo_sapiensENSP0000036293626.829314.9826homo_sapiensENSP0000035295617.53999.79499
ENSG00000100461homo_sapiensENSP0000031319923.66211.831homo_sapiensENSP0000035295619.13449.5672
ENSG00000100461homo_sapiensENSP0000025336362.075551.8868homo_sapiensENSP0000035295674.943162.6424
ENSG00000100461homo_sapiensENSP0000036310918.08879.72696homo_sapiensENSP0000035295624.145812.9841
ENSG00000100461homo_sapiensENSP0000031604225.245914.0984homo_sapiensENSP0000035295617.53999.79499
ENSG00000100461homo_sapiensENSP0000031819512.81696.33803homo_sapiensENSP0000035295620.728910.2506
ENSG00000100461homo_sapiensENSP0000039490224.533313.6homo_sapiensENSP0000035295620.956711.6173
ENSG00000100461homo_sapiensENSP0000035110827.108414.759homo_sapiensENSP0000035295620.501111.1617
ENSG00000100461homo_sapiensENSP0000026174110.20835homo_sapiensENSP0000035295622.323510.9339
ENSG00000100461homo_sapiensENSP0000023307813.02219.09091homo_sapiensENSP0000035295612.07298.42825
ENSG00000100461homo_sapiensENSP0000037212711.49196.65323homo_sapiensENSP0000035295612.98417.51708
ENSG00000100461homo_sapiensENSP0000037210511.49196.65323homo_sapiensENSP0000035295612.98417.51708
ENSG00000100461homo_sapiensENSP0000037248411.49196.65323homo_sapiensENSP0000035295612.98417.51708
ENSG00000100461homo_sapiensENSP0000037215411.49196.65323homo_sapiensENSP0000035295612.98417.51708
ENSG00000100461homo_sapiensENSP0000025083111.29036.65323homo_sapiensENSP0000035295612.75637.51708
ENSG00000100461homo_sapiensENSP0000030715511.29036.65323homo_sapiensENSP0000035295612.75637.51708
ENSG00000100461homo_sapiensENSP0000029547020.238110.4762homo_sapiensENSP0000035295619.362210.0228
ENSG00000100461homo_sapiensENSP0000046602517.171710.101homo_sapiensENSP0000035295611.61736.83371
ENSG00000100461homo_sapiensENSP0000036595028.025519.1083homo_sapiensENSP0000035295610.02286.83371

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000100461homo_sapiensENSP0000035295697.494396.1276nomascus_leucogenysENSNLEP0000001800596.832695.4751
ENSG00000100461homo_sapiensENSP0000035295697.722197.2665pan_paniscusENSPPAP0000002988597.058896.6063
ENSG00000100461homo_sapiensENSP0000035295697.722195.8998pongo_abeliiENSPPYP0000000641997.722195.8998
ENSG00000100461homo_sapiensENSP0000035295698.86197.9499pan_troglodytesENSPTRP0000004034598.1997.2851
ENSG00000100461homo_sapiensENSP0000035295697.949996.8109gorilla_gorillaENSGGOP0000001532698.398297.254
ENSG00000100461homo_sapiensENSP0000035295693.621988.1549ornithorhynchus_anatinusENSOANP0000005086293.409187.9545
ENSG00000100461homo_sapiensENSP0000035295694.53390.4328sarcophilus_harrisiiENSSHAP0000001515992.017788.0266
ENSG00000100461homo_sapiensENSP0000035295655.808754.6697notamacropus_eugeniiENSMEUP0000001329556.192755.0459
ENSG00000100461homo_sapiensENSP0000035295640.774539.8633choloepus_hoffmanniENSCHOP0000000394157.741956.4516
ENSG00000100461homo_sapiensENSP0000035295692.255188.3827dasypus_novemcinctusENSDNOP0000003302792.677388.7872
ENSG00000100461homo_sapiensENSP0000035295692.027387.0159erinaceus_europaeusENSEEUP0000001420590.99186.036
ENSG00000100461homo_sapiensENSP0000035295647.152641.4579echinops_telfairiENSETEP0000001455585.185274.8971
ENSG00000100461homo_sapiensENSP0000035295696.583193.6219callithrix_jacchusENSCJAP0000009286390.987188.1974
ENSG00000100461homo_sapiensENSP0000035295696.355495.2164cercocebus_atysENSCATP0000000553996.136495
ENSG00000100461homo_sapiensENSP0000035295683.826981.3212macaca_fascicularisENSMFAP0000004620679.653777.2727
ENSG00000100461homo_sapiensENSP0000035295696.810995.672macaca_mulattaENSMMUP0000002416796.153895.0226
ENSG00000100461homo_sapiensENSP0000035295696.127695.2164macaca_nemestrinaENSMNEP0000003898396.127695.2164
ENSG00000100461homo_sapiensENSP0000035295696.355495.4442papio_anubisENSPANP0000003902895.485394.5824
ENSG00000100461homo_sapiensENSP0000035295689.749488.6105mandrillus_leucophaeusENSMLEP0000003150894.033492.8401
ENSG00000100461homo_sapiensENSP0000035295693.166389.9772tursiops_truncatusENSTTRP0000000141693.37990.1826
ENSG00000100461homo_sapiensENSP0000035295694.760892.0273vulpes_vulpesENSVVUP0000002695693.483190.7865
ENSG00000100461homo_sapiensENSP0000035295692.255188.6105equus_asinusENSEASP0000505713673.369670.471
ENSG00000100461homo_sapiensENSP0000035295694.988691.5718capra_hircusENSCHIP0000003128387.789584.6316
ENSG00000100461homo_sapiensENSP0000035295689.977285.6492loxodonta_africanaENSLAFP0000001556488.366984.1163
ENSG00000100461homo_sapiensENSP0000035295695.216491.7995panthera_leoENSPLOP0000001361493.932690.5618
ENSG00000100461homo_sapiensENSP0000035295693.849792.0273ailuropoda_melanoleucaENSAMEP0000000773292.376790.583
ENSG00000100461homo_sapiensENSP0000035295693.849790.8884bos_indicus_hybridENSBIXP0000502160086.373283.6478
ENSG00000100461homo_sapiensENSP0000035295693.621990.6606oryctolagus_cuniculusENSOCUP0000000173492.567689.6396
ENSG00000100461homo_sapiensENSP0000035295694.760892.4829equus_caballusENSECAP0000005255292.650390.4232
ENSG00000100461homo_sapiensENSP0000035295694.988691.7995canis_lupus_familiarisENSCAFP0084500312593.707990.5618
ENSG00000100461homo_sapiensENSP0000035295695.216491.7995panthera_pardusENSPPRP0000000256893.932690.5618
ENSG00000100461homo_sapiensENSP0000035295683.371380.1822marmota_marmota_marmotaENSMMMP0000001543392.893489.3401
ENSG00000100461homo_sapiensENSP0000035295693.394190.4328balaenoptera_musculusENSBMSP0001001418476.635574.2056
ENSG00000100461homo_sapiensENSP0000035295694.53392.2551ursus_americanusENSUAMP0000001037193.049390.8072
ENSG00000100461homo_sapiensENSP0000035295692.027386.3326monodelphis_domesticaENSMODP0000004772682.44977.3469
ENSG00000100461homo_sapiensENSP0000035295694.077490.8884bison_bison_bisonENSBBBP0000001593291.574388.4701
ENSG00000100461homo_sapiensENSP0000035295693.621990.4328monodon_monocerosENSMMNP0001501463589.73886.6812
ENSG00000100461homo_sapiensENSP0000035295691.116288.6105sus_scrofaENSSSCP0000003593693.240190.676
ENSG00000100461homo_sapiensENSP0000035295694.305292.2551microcebus_murinusENSMICP0000004655993.665291.629
ENSG00000100461homo_sapiensENSP0000035295690.888486.5604ovis_aries_rambouilletENSOARP0002002426362.441359.4679
ENSG00000100461homo_sapiensENSP0000035295694.53392.2551ursus_maritimusENSUMAP0000001916193.049390.8072
ENSG00000100461homo_sapiensENSP0000035295692.027388.1549ochotona_princepsENSOPRP0000000100991.402787.5566
ENSG00000100461homo_sapiensENSP0000035295692.482989.7494delphinapterus_leucasENSDLEP0000002778892.906290.1602
ENSG00000100461homo_sapiensENSP0000035295694.760891.5718physeter_catodonENSPCTP0000501339394.545591.3636
ENSG00000100461homo_sapiensENSP0000035295659.908958.9977dipodomys_ordiiENSDORP0000000461097.769596.2825
ENSG00000100461homo_sapiensENSP0000035295694.077491.344mustela_putorius_furoENSMPUP0000000709493.01890.3153
ENSG00000100461homo_sapiensENSP0000035295677.22171.5262aotus_nancymaaeENSANAP0000003224690.641783.9572
ENSG00000100461homo_sapiensENSP0000035295636.446534.6241aotus_nancymaaeENSANAP0000002726889.385584.9162
ENSG00000100461homo_sapiensENSP0000035295669.703965.1481saimiri_boliviensis_boliviensisENSSBOP0000003780383.606678.1421
ENSG00000100461homo_sapiensENSP0000035295682.460180.1822saimiri_boliviensis_boliviensisENSSBOP0000001252597.050994.37
ENSG00000100461homo_sapiensENSP0000035295639.407738.9522vicugna_pacosENSVPAP0000000055556.721356.0656
ENSG00000100461homo_sapiensENSP0000035295696.127694.9886chlorocebus_sabaeusENSCSAP0000001228195.475194.3439
ENSG00000100461homo_sapiensENSP0000035295691.34487.4715tupaia_belangeriENSTBEP0000000997993.039489.0951
ENSG00000100461homo_sapiensENSP0000035295691.116286.5604phocoena_sinusENSPSNP0000002565987.527483.151
ENSG00000100461homo_sapiensENSP0000035295694.988692.2551camelus_dromedariusENSCDRP0000501095592.666790
ENSG00000100461homo_sapiensENSP0000035295694.988692.2551camelus_dromedariusENSCDRP0000502022287.421484.9057
ENSG00000100461homo_sapiensENSP0000035295694.305291.7995carlito_syrichtaENSTSYP0000001777393.033790.5618
ENSG00000100461homo_sapiensENSP0000035295694.53391.1162panthera_tigris_altaicaENSPTIP0000000577694.104390.7029
ENSG00000100461homo_sapiensENSP0000035295695.67293.3941prolemur_simusENSPSMP0000000729894.38292.1348
ENSG00000100461homo_sapiensENSP0000035295694.305290.8884sorex_araneusENSSARP0000000467593.033789.6629
ENSG00000100461homo_sapiensENSP0000035295693.849790.8884bos_mutusENSBMUP0000002483178.927276.4368
ENSG00000100461homo_sapiensENSP0000035295692.255189.2938pteropus_vampyrusENSPVAP0000001300093.31890.3226
ENSG00000100461homo_sapiensENSP0000035295689.749485.4214myotis_lucifugusENSMLUP0000001175890.783486.4055
ENSG00000100461homo_sapiensENSP0000035295693.849789.5216vombatus_ursinusENSVURP0001002684492.376788.1166
ENSG00000100461homo_sapiensENSP0000035295692.710791.344rhinolophus_ferrumequinumENSRFEP0001000132693.13591.762
ENSG00000100461homo_sapiensENSP0000035295694.305291.5718neovison_visonENSNVIP0000002688593.243290.5405
ENSG00000100461homo_sapiensENSP0000035295693.621990.4328bos_taurusENSBTAP0000006031688.577685.5603
ENSG00000100461homo_sapiensENSP0000035295689.066183.8269heterocephalus_glaber_femaleENSHGLP0000004129489.473784.2105
ENSG00000100461homo_sapiensENSP0000035295696.810995.2164rhinopithecus_bietiENSRBIP0000003086196.153894.5701
ENSG00000100461homo_sapiensENSP0000035295694.988691.7995canis_lupus_dingoENSCAFP0002000951793.707990.5618
ENSG00000100461homo_sapiensENSP0000035295695.444292.4829sciurus_vulgarisENSSVLP0000500408894.369491.4414
ENSG00000100461homo_sapiensENSP0000035295693.849789.7494phascolarctos_cinereusENSPCIP0000003771691.555687.5556
ENSG00000100461homo_sapiensENSP0000035295675.626469.0205procavia_capensisENSPCAP0000000626279.425872.488
ENSG00000100461homo_sapiensENSP0000035295693.849791.1162bos_grunniensENSBGRP0000000685586.373283.8574
ENSG00000100461homo_sapiensENSP0000035295695.216492.2551cervus_hanglu_yarkandensisENSCHYP0000002733590.280887.473
ENSG00000100461homo_sapiensENSP0000035295689.977287.6993catagonus_wagneriENSCWAP0000002748288.169685.9375
ENSG00000100461homo_sapiensENSP0000035295660.136758.9977ictidomys_tridecemlineatusENSSTOP0000000930498.507596.6418
ENSG00000100461homo_sapiensENSP0000035295688.610584.738otolemur_garnettiiENSOGAP0000001325389.631385.7143
ENSG00000100461homo_sapiensENSP0000035295697.494395.2164cebus_imitatorENSCCAP0000001463097.716995.4338
ENSG00000100461homo_sapiensENSP0000035295681.093474.7153cebus_imitatorENSCCAP0000002155686.407879.6116
ENSG00000100461homo_sapiensENSP0000035295682.915779.7267urocitellus_parryiiENSUPAP0001001401192.857189.2857
ENSG00000100461homo_sapiensENSP0000035295692.482988.3827moschus_moschiferusENSMMSP0000000413760.687657.997
ENSG00000100461homo_sapiensENSP0000035295696.810995.2164rhinopithecus_roxellanaENSRROP0000004169996.153894.5701
ENSG00000100461homo_sapiensENSP0000035295695.444292.9385propithecus_coquereliENSPCOP0000001383694.157391.6854
ENSG00000100461homo_sapiensENSP0000035295676.993266.0592xenopus_tropicalisENSXETP0000011739075.278464.588
ENSG00000100461homo_sapiensENSP0000035295680.637871.5262chrysemys_picta_belliiENSCPBP0000003768080.272171.2018
ENSG00000100461homo_sapiensENSP0000035295682.460174.0319sphenodon_punctatusENSSPUP0000000054279.735771.5859
ENSG00000100461homo_sapiensENSP0000035295684.282576.5376laticauda_laticaudataENSLLTP0000002249179.569972.2581
ENSG00000100461homo_sapiensENSP0000035295683.599175.6264notechis_scutatusENSNSUP0000002036679.265771.7063
ENSG00000100461homo_sapiensENSP0000035295683.826975.6264notechis_scutatusENSNSUP0000002380279.139871.3979
ENSG00000100461homo_sapiensENSP0000035295683.826975.8542pseudonaja_textilisENSPTXP0000001440579.481671.9222
ENSG00000100461homo_sapiensENSP0000035295677.448769.0205pseudonaja_textilisENSPTXP0000001583980.952472.1429
ENSG00000100461homo_sapiensENSP0000035295619.362215.4897anas_platyrhynchos_platyrhynchosENSAPLP0000002997279.439363.5514
ENSG00000100461homo_sapiensENSP0000035295684.510376.5376anolis_carolinensisENSACAP0000000161679.613772.103
ENSG00000100461homo_sapiensENSP0000035295684.510376.3098naja_najaENSNNAP0000000647874.49867.2691
ENSG00000100461homo_sapiensENSP0000035295641.457938.4966naja_najaENSNNAP0000001650383.10577.169
ENSG00000100461homo_sapiensENSP0000035295642.596838.9522taeniopygia_guttataENSTGUP0000003254078.571471.8487
ENSG00000100461homo_sapiensENSP0000035295646.241541.6856taeniopygia_guttataENSTGUP0000003258090.62581.6964
ENSG00000100461homo_sapiensENSP0000035295679.954471.9818salvator_merianaeENSSMRP0000000560174.050666.6667
ENSG00000100461homo_sapiensENSP0000035295679.043368.7927leptobrachium_leishanenseENSLLEP0000001593684.019473.1235

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IEAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1IEAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0045893involved_in positive regulation of DNA-templated transcription1IDAHomo_sapiens(9606)Process
GO:0048024involved_in regulation of mRNA splicing, via spliceosome2IBA,IDAHomo_sapiens(9606)Process
GO:1990446enables U1 snRNP binding1IBAHomo_sapiens(9606)Function

Expression