RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000094914	Gene ID	8086	Accession	13666
Symbol	AAAS	Alias	AAA;AAASb;GL003;ALADIN;ADRACALA;ADRACALIN	Full Name	aladin WD repeat nucleoporin
Status	Confidence	Length	17303 bases	Strand	Minus strand
Position	12 : 53307456 - 53324758	RNA binding domain	N.A.
Summary	The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
AAAS-212	ENST00000548931	1109	358aa	ENSP00000457518
AAAS-220	ENST00000552876	2016	No protein	-
AAAS-213	ENST00000549450	1606	No protein	-
AAAS-202	ENST00000394384	1703	513aa	ENSP00000377908
AAAS-201	ENST00000209873	1815	546aa	ENSP00000209873
AAAS-217	ENST00000550286	1652	422aa	ENSP00000446885
AAAS-208	ENST00000547757	2292	127aa	ENSP00000448020
AAAS-204	ENST00000546562	2690	No protein	-
AAAS-206	ENST00000547238	2248	No protein	-
AAAS-221	ENST00000672797	2101	No protein	-
AAAS-207	ENST00000547520	1705	No protein	-
AAAS-219	ENST00000552161	2566	No protein	-
AAAS-211	ENST00000548880	1937	No protein	-
AAAS-216	ENST00000550033	900	No protein	-
AAAS-222	ENST00000672900	2583	No protein	-
AAAS-203	ENST00000546393	1883	No protein	-
AAAS-205	ENST00000546572	582	No protein	-
AAAS-209	ENST00000547761	827	No protein	-
AAAS-215	ENST00000549983	860	No protein	-
AAAS-214	ENST00000549821	596	No protein	-
AAAS-210	ENST00000548258	550	No protein	-
AAAS-218	ENST00000551724	552	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000922	located_in spindle pole	1	IDA	Homo_sapiens(9606)	Component
GO:0001578	involved_in microtubule bundle formation	1	IMP	Homo_sapiens(9606)	Process
GO:0003674	enables molecular_function	1	ND	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	HDA	Homo_sapiens(9606)	Component
GO:0005635	located_in nuclear envelope	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005643	part_of nuclear pore	3	IBA,IDA,NAS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005813	located_in centrosome	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	IDA	Homo_sapiens(9606)	Component
GO:0006913	involved_in nucleocytoplasmic transport	3	IBA,IDA,NAS	Homo_sapiens(9606)	Process
GO:0007612	involved_in learning	1	IEA	Homo_sapiens(9606)	Process
GO:0009566	involved_in fertilization	1	IEA	Homo_sapiens(9606)	Process
GO:0015031	involved_in protein transport	1	IEA	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0031965	located_in nuclear membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0046822	involved_in regulation of nucleocytoplasmic transport	1	NAS	Homo_sapiens(9606)	Process
GO:0051028	involved_in mRNA transport	1	IEA	Homo_sapiens(9606)	Process
GO:0072686	located_in mitotic spindle	1	IDA	Homo_sapiens(9606)	Component
GO:0090307	involved_in mitotic spindle assembly	1	IMP	Homo_sapiens(9606)	Process