RBP Type	Canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000092098	Gene ID	55072	Accession	16031
Symbol	RNF31	Alias	HOIP;Paul;ZIBRA	Full Name	ring finger protein 31
Status	Confidence	Length	13978 bases	Strand	Plus strand
Position	14 : 24146683 - 24160660	RNA binding domain	zf-RanBP
Summary	The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The encoded protein is the E3 ubiquitin-protein ligase component of the linear ubiquitin chain assembly complex. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000453601	zf-RanBP	PF00641	3.2e-06	1
ENSP00000453601	zf-RanBP	PF00641	3.2e-06	2

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
RNF31-225	ENST00000560875	550	56aa	ENSP00000454032
RNF31-212	ENST00000559308	559	52aa	ENSP00000453471
RNF31-207	ENST00000558634	537	No protein	-
RNF31-204	ENST00000557878	574	No protein	-
RNF31-216	ENST00000559533	3192	887aa	ENSP00000454048
RNF31-205	ENST00000557991	578	170aa	ENSP00000453423
RNF31-213	ENST00000559438	557	No protein	-
RNF31-220	ENST00000560071	576	60aa	ENSP00000453948
RNF31-211	ENST00000559275	3198	921aa	ENSP00000453574
RNF31-226	ENST00000699882	3948	No protein	-
RNF31-206	ENST00000558452	3623	No protein	-
RNF31-201	ENST00000324103	3502	1072aa	ENSP00000315112
RNF31-228	ENST00000699884	3744	No protein	-
RNF31-229	ENST00000699885	3451	1055aa	ENSP00000514674
RNF31-227	ENST00000699883	3879	No protein	-
RNF31-219	ENST00000559882	554	No protein	-
RNF31-210	ENST00000559260	551	32aa	ENSP00000453645
RNF31-230	ENST00000699886	3561	203aa	ENSP00000514675
RNF31-231	ENST00000699887	3407	286aa	ENSP00000514676
RNF31-208	ENST00000558907	1614	494aa	ENSP00000453601
RNF31-232	ENST00000699888	3544	No protein	-
RNF31-233	ENST00000699889	4054	No protein	-
RNF31-221	ENST00000560342	888	No protein	-
RNF31-234	ENST00000699890	2538	No protein	-
RNF31-235	ENST00000699891	4002	No protein	-
RNF31-224	ENST00000560787	2834	917aa	ENSP00000452972
RNF31-217	ENST00000559583	1147	No protein	-
RNF31-203	ENST00000491351	1957	623aa	ENSP00000453595
RNF31-209	ENST00000559071	1943	No protein	-
RNF31-223	ENST00000560754	606	No protein	-
RNF31-236	ENST00000699892	673	No protein	-
RNF31-214	ENST00000559449	808	140aa	ENSP00000454140
RNF31-202	ENST00000483895	660	143aa	ENSP00000453672
RNF31-218	ENST00000559719	579	165aa	ENSP00000452820
RNF31-215	ENST00000559491	478	No protein	-
RNF31-222	ENST00000560631	320	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
41426	Platelet Function Tests	1.6444800E-005	-
45248	Platelet Function Tests	1.0174524E-006	-
45289	Platelet Function Tests	1.1570719E-006	-
45366	Platelet Function Tests	8.0829820E-006	-
106561	Suicide	8E-6	26079190

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000209	involved_in protein polyubiquitination	1	IDA	Homo_sapiens(9606)	Process
GO:0004842	enables ubiquitin-protein transferase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0009898	located_in cytoplasmic side of plasma membrane	1	ISS	Homo_sapiens(9606)	Component
GO:0023035	involved_in CD40 signaling pathway	1	ISS	Homo_sapiens(9606)	Process
GO:0031625	enables ubiquitin protein ligase binding	1	IPI	Homo_sapiens(9606)	Function
GO:0035631	part_of CD40 receptor complex	1	ISS	Homo_sapiens(9606)	Component
GO:0036435	enables K48-linked polyubiquitin modification-dependent protein binding	1	IBA	Homo_sapiens(9606)	Function
GO:0042742	involved_in defense response to bacterium	1	IDA	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0043123	involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling	1	IDA	Homo_sapiens(9606)	Process
GO:0043130	enables ubiquitin binding	1	IDA	Homo_sapiens(9606)	Function
GO:0050852	involved_in T cell receptor signaling pathway	1	IDA	Homo_sapiens(9606)	Process
GO:0051092	involved_in positive regulation of NF-kappaB transcription factor activity	1	IDA	Homo_sapiens(9606)	Process
GO:0060546	involved_in negative regulation of necroptotic process	1	IEA	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0070530	enables K63-linked polyubiquitin modification-dependent protein binding	1	IBA	Homo_sapiens(9606)	Function
GO:0071797	part_of LUBAC complex	2	IDA,IPI	Homo_sapiens(9606)	Component
GO:0097039	involved_in protein linear polyubiquitination	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:1903955	involved_in positive regulation of protein targeting to mitochondrion	1	HMP	Homo_sapiens(9606)	Process
GO:1904417	involved_in positive regulation of xenophagy	1	IDA	Homo_sapiens(9606)	Process
GO:1990450	enables linear polyubiquitin binding	1	IBA	Homo_sapiens(9606)	Function