RBP Type	Canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000080561	Gene ID	11043	Accession	7096
Symbol	MID2	Alias	FXY2;RNF60;TRIM1;MRX101;XLID101	Full Name	midline 2
Status	Confidence	Length	105883 bases	Strand	Plus strand
Position	X : 107825755 - 107931637	RNA binding domain	SPRY
Summary	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to microtubular structures in the cytoplasm. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000413976	SPRY	PF00622	3e-10	1
ENSP00000262843	SPRY	PF00622	3.2e-10	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
MID2-203	ENST00000451923	758	218aa	ENSP00000410730
MID2-201	ENST00000262843	7333	735aa	ENSP00000262843
MID2-202	ENST00000443968	2251	705aa	ENSP00000413976
MID2-204	ENST00000474517	689	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
4653	Cholesterol	1.72200971455582E-6	17903299

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003713	enables transcription coactivator activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005737	located_in cytoplasm	1	IEA	Homo_sapiens(9606)	Component
GO:0005874	colocalizes_with microtubule	3	IBA,IDA	Homo_sapiens(9606)	Component
GO:0008017	enables microtubule binding	2	IBA,IMP	Homo_sapiens(9606)	Function
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0010508	involved_in positive regulation of autophagy	1	IMP	Homo_sapiens(9606)	Process
GO:0016567	involved_in protein ubiquitination	1	IEA	Homo_sapiens(9606)	Process
GO:0016740	enables transferase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0019899	enables enzyme binding	1	IPI	Homo_sapiens(9606)	Function
GO:0032897	involved_in negative regulation of viral transcription	1	IDA	Homo_sapiens(9606)	Process
GO:0035372	involved_in protein localization to microtubule	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0042803	enables protein homodimerization activity	1	IDA	Homo_sapiens(9606)	Function
GO:0043123	involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling	1	IDA	Homo_sapiens(9606)	Process
GO:0044790	involved_in suppression of viral release by host	1	IDA	Homo_sapiens(9606)	Process
GO:0045087	involved_in innate immune response	1	IDA	Homo_sapiens(9606)	Process
GO:0045893	involved_in positive regulation of DNA-templated transcription	1	IEA	Homo_sapiens(9606)	Process
GO:0046597	involved_in negative regulation of viral entry into host cell	1	IDA	Homo_sapiens(9606)	Process
GO:0051091	involved_in positive regulation of DNA-binding transcription factor activity	1	IMP	Homo_sapiens(9606)	Process
GO:0051092	involved_in positive regulation of NF-kappaB transcription factor activity	1	IMP	Homo_sapiens(9606)	Process
GO:0051219	enables phosphoprotein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component