| RBP Type |
Canonical_RBPs |
| Diseases |
Cancer |
| Drug |
N.A. |
| Main interacting RNAs |
mRNA |
| Moonlighting functions |
N.A. |
| Localizations |
N.A. |
|
BulkPerturb-seq
|
N.A. |
| Ensembl ID | ENSG00000080007 | Gene ID |
55510 |
Accession |
18677 |
| Symbol |
DDX43 |
Alias |
|
Full Name |
|
| Status |
Confidence |
Length |
22739 bases |
Strand |
Plus strand |
| Position |
6 : 73394828 - 73417566 |
RNA binding domain |
DEAD , KH_1 |
| Summary |
|
RNA binding domains (RBDs)
| Protein |
Domain |
Pfam ID |
E-value |
Domain number |
| ENSP00000359361 |
DEAD |
PF00270 |
3e-43 |
1 |
| ENSP00000359361 |
KH_1 |
PF00013 |
8.3e-12 |
2 |
RNA binding proteomes (RBPomes)
| Pubmed ID |
Full Name |
Cell |
Author |
Time |
Doi |
Literatures on RNA binding capacity
| Pubmed ID |
Title |
Author |
Time |
Journal |
| 37120627 |
Single-cell RNA-seq uncovers dynamic processes orchestrated by RNA-binding protein DDX43 in chromatin remodeling during spermiogenesis. |
Huanhuan Tan |
2023-04-29 |
Nature communications |
| 29150525 |
Distinct RNA-unwinding mechanisms of DEAD-box and DEAH-box RNA helicase proteins in remodeling structured RNAs and RNPs. |
Benjamin Gilman |
2017-12-15 |
Biochemical Society transactions |
| 33555135 |
DEAD-box polypeptide 43 facilitates piRNA amplification by actively liberating RNA from Ago3-piRISC. |
Ryo Murakami |
2021-04-07 |
EMBO reports |
| 28468824 |
The DEAD-box protein DDX43 (HAGE) is a dual RNA-DNA helicase and has a K-homology domain required for full nucleic acid unwinding activity. |
Tanu Talwar |
2017-06-23 |
The Journal of biological chemistry |
| Name |
Transcript ID |
bp |
Protein |
Translation ID |
| Pathway ID |
Pathway Name |
Source |
| | |
| ensgID |
Trait |
pValue |
Pubmed ID |
| 52626 | Creatinine | 7.2950000E-006 | - |
| 52628 | Creatinine | 5.0790000E-006 | - |
| 52634 | Creatinine | 2.3390000E-005 | - |
| ensgID | SNP | Chromosome | Position |
Trait | PubmedID | Or or BEAT |
EFO ID |
|---|
Protein-Protein Interaction (PPI)
| Ensembl ID |
Source |
Target |
| Species |
Protein ID |
Perc_pos |
Perc_id |
Species |
Protein ID |
Perc_pos |
Perc_id |
| ENSG00000080007 | homo_sapiens | ENSP00000379475 | 50.7009 | 26.8692 | homo_sapiens | ENSP00000359361 | 33.4877 | 17.7469 |
| ENSG00000080007 | homo_sapiens | ENSP00000385536 | 40.8779 | 29.2181 | homo_sapiens | ENSP00000359361 | 45.9877 | 32.8704 |
| ENSG00000080007 | homo_sapiens | ENSP00000263239 | 37.0149 | 21.194 | homo_sapiens | ENSP00000359361 | 38.2716 | 21.9136 |
| ENSG00000080007 | homo_sapiens | ENSP00000497641 | 48.9051 | 30.6569 | homo_sapiens | ENSP00000359361 | 31.0185 | 19.4444 |
| ENSG00000080007 | homo_sapiens | ENSP00000482680 | 32.6797 | 19.7386 | homo_sapiens | ENSP00000359361 | 38.5802 | 23.3025 |
| ENSG00000080007 | homo_sapiens | ENSP00000293831 | 51.9704 | 32.5123 | homo_sapiens | ENSP00000359361 | 32.5617 | 20.3704 |
| ENSG00000080007 | homo_sapiens | ENSP00000306117 | 44.1423 | 24.0586 | homo_sapiens | ENSP00000359361 | 32.5617 | 17.7469 |
| ENSG00000080007 | homo_sapiens | ENSP00000288071 | 44.2589 | 24.2171 | homo_sapiens | ENSP00000359361 | 32.716 | 17.9012 |
| ENSG00000080007 | homo_sapiens | ENSP00000481495 | 30.2678 | 17.1129 | homo_sapiens | ENSP00000359361 | 40.1235 | 22.6852 |
| ENSG00000080007 | homo_sapiens | ENSP00000416534 | 30.4264 | 18.7015 | homo_sapiens | ENSP00000359361 | 48.4568 | 29.784 |
| ENSG00000080007 | homo_sapiens | ENSP00000361232 | 30.1609 | 17.9625 | homo_sapiens | ENSP00000359361 | 34.7222 | 20.679 |
| ENSG00000080007 | homo_sapiens | ENSP00000492643 | 16.0902 | 8.7218 | homo_sapiens | ENSP00000359361 | 33.0247 | 17.9012 |
| ENSG00000080007 | homo_sapiens | ENSP00000238146 | 33.5 | 20 | homo_sapiens | ENSP00000359361 | 31.0185 | 18.5185 |
| ENSG00000080007 | homo_sapiens | ENSP00000225792 | 50.1629 | 35.5049 | homo_sapiens | ENSP00000359361 | 47.5309 | 33.642 |
| ENSG00000080007 | homo_sapiens | ENSP00000368667 | 76.7036 | 60.6973 | homo_sapiens | ENSP00000359361 | 74.6914 | 59.1049 |
| ENSG00000080007 | homo_sapiens | ENSP00000330460 | 39.2569 | 22.9402 | homo_sapiens | ENSP00000359361 | 37.5 | 21.9136 |
| ENSG00000080007 | homo_sapiens | ENSP00000263576 | 40.9938 | 23.6025 | homo_sapiens | ENSP00000359361 | 30.5556 | 17.5926 |
| ENSG00000080007 | homo_sapiens | ENSP00000380495 | 32.7327 | 18.4685 | homo_sapiens | ENSP00000359361 | 33.642 | 18.9815 |
| ENSG00000080007 | homo_sapiens | ENSP00000314348 | 24.6857 | 14.8571 | homo_sapiens | ENSP00000359361 | 33.3333 | 20.0617 |
| ENSG00000080007 | homo_sapiens | ENSP00000346120 | 32.4393 | 19.6679 | homo_sapiens | ENSP00000359361 | 39.1975 | 23.7654 |
| ENSG00000080007 | homo_sapiens | ENSP00000374574 | 33.4755 | 21.1087 | homo_sapiens | ENSP00000359361 | 48.4568 | 30.5556 |
| ENSG00000080007 | homo_sapiens | ENSP00000358716 | 24.5146 | 15.534 | homo_sapiens | ENSP00000359361 | 31.1728 | 19.7531 |
| ENSG00000080007 | homo_sapiens | ENSP00000442266 | 43.4783 | 27.3292 | homo_sapiens | ENSP00000359361 | 32.4074 | 20.3704 |
| ENSG00000080007 | homo_sapiens | ENSP00000362687 | 32.7001 | 20.2171 | homo_sapiens | ENSP00000359361 | 37.1914 | 22.9938 |
| ENSG00000080007 | homo_sapiens | ENSP00000479504 | 42.0701 | 24.8748 | homo_sapiens | ENSP00000359361 | 38.8889 | 22.9938 |
| ENSG00000080007 | homo_sapiens | ENSP00000326381 | 51.1057 | 32.9238 | homo_sapiens | ENSP00000359361 | 32.0988 | 20.679 |
| ENSG00000080007 | homo_sapiens | ENSP00000258772 | 34.5521 | 20.6581 | homo_sapiens | ENSP00000359361 | 29.1667 | 17.4383 |
| ENSG00000080007 | homo_sapiens | ENSP00000494040 | 41.5408 | 27.1903 | homo_sapiens | ENSP00000359361 | 42.4383 | 27.7778 |
| ENSG00000080007 | homo_sapiens | ENSP00000336725 | 41.3636 | 27.1212 | homo_sapiens | ENSP00000359361 | 42.1296 | 27.6235 |
| ENSG00000080007 | homo_sapiens | ENSP00000247003 | 41.8219 | 26.294 | homo_sapiens | ENSP00000359361 | 31.1728 | 19.5988 |
| ENSG00000080007 | homo_sapiens | ENSP00000330349 | 40.5145 | 27.0096 | homo_sapiens | ENSP00000359361 | 38.8889 | 25.9259 |
| ENSG00000080007 | homo_sapiens | ENSP00000242776 | 50.1171 | 28.103 | homo_sapiens | ENSP00000359361 | 33.0247 | 18.5185 |
| ENSG00000080007 | homo_sapiens | ENSP00000233084 | 30.5405 | 18.5135 | homo_sapiens | ENSP00000359361 | 34.8765 | 21.142 |
| ENSG00000080007 | homo_sapiens | ENSP00000304072 | 28.7174 | 16.2316 | homo_sapiens | ENSP00000359361 | 39.0432 | 22.0679 |
| ENSG00000080007 | homo_sapiens | ENSP00000350698 | 44.8352 | 29.6703 | homo_sapiens | ENSP00000359361 | 31.4815 | 20.8333 |
| ENSG00000080007 | homo_sapiens | ENSP00000310723 | 34.0244 | 21.9512 | homo_sapiens | ENSP00000359361 | 43.0556 | 27.7778 |
| ENSG00000080007 | homo_sapiens | ENSP00000332340 | 40.1852 | 23.3333 | homo_sapiens | ENSP00000359361 | 33.4877 | 19.4444 |
| ENSG00000080007 | homo_sapiens | ENSP00000424838 | 36.1878 | 23.7569 | homo_sapiens | ENSP00000359361 | 40.4321 | 26.5432 |
| Ensembl ID |
Source |
Target |
| Species |
Protein ID |
Perc_pos |
Perc_id |
Species |
Protein ID |
Perc_pos |
Perc_id |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 97.8395 | 96.2963 | nomascus_leucogenys | ENSNLEP00000001498 | 97.6888 | 96.1479 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 99.6914 | 99.0741 | pan_paniscus | ENSPPAP00000021999 | 99.6914 | 99.0741 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 98.4568 | 97.2222 | pongo_abelii | ENSPPYP00000018772 | 98.4568 | 97.2222 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 99.6914 | 99.0741 | pan_troglodytes | ENSPTRP00000041157 | 99.6914 | 99.0741 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 99.537 | 98.7654 | gorilla_gorilla | ENSGGOP00000021434 | 99.537 | 98.7654 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 92.7469 | 87.8086 | callithrix_jacchus | ENSCJAP00000018337 | 94.4969 | 89.4654 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 98.1481 | 96.7593 | cercocebus_atys | ENSCATP00000015849 | 98.1481 | 96.7593 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 97.9938 | 96.7593 | macaca_fascicularis | ENSMFAP00000022781 | 97.9938 | 96.7593 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 97.9938 | 96.7593 | macaca_mulatta | ENSMMUP00000025745 | 97.9938 | 96.7593 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 93.6728 | 92.5926 | macaca_nemestrina | ENSMNEP00000030142 | 97.9032 | 96.7742 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 97.9938 | 96.6049 | papio_anubis | ENSPANP00000016001 | 97.9938 | 96.6049 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 97.3765 | 96.142 | mandrillus_leucophaeus | ENSMLEP00000035639 | 97.9814 | 96.7391 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 84.4136 | 72.0679 | panthera_leo | ENSPLOP00000021714 | 87.1019 | 74.3631 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 87.5 | 76.3889 | canis_lupus_familiaris | ENSCAFP00845016779 | 87.907 | 76.7442 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 84.4136 | 72.2222 | panthera_pardus | ENSPPRP00000024294 | 87.1019 | 74.5223 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 84.1049 | 72.5309 | balaenoptera_musculus | ENSBMSP00010023255 | 85.0234 | 73.3229 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 74.8457 | 66.358 | microcebus_murinus | ENSMICP00000015626 | 91.8561 | 81.4394 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 77.4691 | 67.9012 | ovis_aries_rambouillet | ENSOARP00020034232 | 83.1126 | 72.8477 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 83.7963 | 72.2222 | physeter_catodon | ENSPCTP00005031308 | 84.5794 | 72.8972 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 93.3642 | 87.6543 | aotus_nancymaae | ENSANAP00000021799 | 93.6533 | 87.9257 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 84.2593 | 80.4012 | saimiri_boliviensis_boliviensis | ENSSBOP00000016540 | 93.1741 | 88.9079 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 98.1481 | 96.6049 | chlorocebus_sabaeus | ENSCSAP00000010120 | 97.8462 | 96.3077 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 86.2654 | 79.4753 | carlito_syrichta | ENSTSYP00000003348 | 87.8931 | 80.9748 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 75.3086 | 66.9753 | prolemur_simus | ENSPSMP00000005710 | 92.4242 | 82.197 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 81.9444 | 70.9877 | bos_mutus | ENSBMUP00000026258 | 82.9688 | 71.875 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 87.1914 | 77.9321 | rhinolophus_ferrumequinum | ENSRFEP00010021743 | 87.3261 | 78.0526 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 80.5556 | 79.321 | rhinopithecus_bieti | ENSRBIP00000039591 | 98.6768 | 97.1645 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 87.5 | 78.0864 | sciurus_vulgaris | ENSSVLP00005011063 | 88.1804 | 78.6936 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 84.2593 | 72.6852 | catagonus_wagneri | ENSCWAP00000011266 | 84.9145 | 73.2504 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 87.6543 | 79.321 | otolemur_garnettii | ENSOGAP00000012235 | 87.5193 | 79.1988 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 82.0988 | 77.9321 | cebus_imitator | ENSCCAP00000039008 | 94.6619 | 89.8577 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 97.6852 | 95.9877 | rhinopithecus_roxellana | ENSRROP00000014425 | 97.6852 | 95.9877 |
| ENSG00000080007 | homo_sapiens | ENSP00000359361 | 66.821 | 58.7963 | propithecus_coquereli | ENSPCOP00000016695 | 91.3502 | 80.3797 |
| Go ID |
Go term |
No. evidence |
Entries |
Species |
Category |
| GO:0003723 | enables RNA binding | 1 | IBA | Homo_sapiens(9606) | Function |
| GO:0003724 | enables RNA helicase activity | 1 | IBA | Homo_sapiens(9606) | Function |
| GO:0005515 | enables protein binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0005524 | enables ATP binding | 1 | IEA | Homo_sapiens(9606) | Function |
| GO:0016887 | enables ATP hydrolysis activity | 1 | IEA | Homo_sapiens(9606) | Function |
