RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000076716	Gene ID	2239	Accession	4452
Symbol	GPC4	Alias	KPTS;K-glypican	Full Name	glypican 4
Status	Confidence	Length	115387 bases	Strand	Minus strand
Position	X : 133300103 - 133415489	RNA binding domain	N.A.
Summary	Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
GPC4-201	ENST00000370828	4959	556aa	ENSP00000359864

Gene Model

Click here to download ENSG00000076716's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
2127	Body Mass Index	4.25827720586365E-5	17903300
2131	Body Mass Index	4.2582772058708E-5	17903300
2408	Body Mass Index	7.15715792974654E-5	17903300
2409	Body Mass Index	7.15715792973803E-5	17903300
2421	Body Mass Index	9.7391619140625E-5	17903300
2423	Body Mass Index	9.73916191406854E-5	17903300

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000076716's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	HDA	Homo_sapiens(9606)	Component
GO:0005796	located_in Golgi lumen	1	TAS	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0009897	located_in external side of plasma membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0009966	involved_in regulation of signal transduction	1	IEA	Homo_sapiens(9606)	Process
GO:0009986	is_active_in cell surface	1	IBA	Homo_sapiens(9606)	Component
GO:0016055	involved_in Wnt signaling pathway	1	IMP	Homo_sapiens(9606)	Process
GO:0016477	involved_in cell migration	1	IBA	Homo_sapiens(9606)	Process
GO:0043202	located_in lysosomal lumen	1	TAS	Homo_sapiens(9606)	Component
GO:0045202	is_active_in synapse	1	IBA	Homo_sapiens(9606)	Component
GO:0060071	involved_in Wnt signaling pathway, planar cell polarity pathway	1	IEA	Homo_sapiens(9606)	Process
GO:0062023	located_in collagen-containing extracellular matrix	1	IEA	Homo_sapiens(9606)	Component
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component
GO:0098696	involved_in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	1	IBA	Homo_sapiens(9606)	Process
GO:0098978	located_in glutamatergic synapse	1	IEA	Homo_sapiens(9606)	Component
GO:0099560	involved_in synaptic membrane adhesion	1	IBA	Homo_sapiens(9606)	Process
GO:1904929	enables coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	1	NAS	Homo_sapiens(9606)	Function
GO:1905606	involved_in regulation of presynapse assembly	1	IBA	Homo_sapiens(9606)	Process

Expression