RBP Type
Non-canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
Metabolic enzyme
Localizations
N.A.
BulkPerturb-seq
Ensembl ID ENSG00000076685 Gene ID
22978 Accession
8022
Symbol
NT5C2
Alias
GMP;NT5B;PNT5;SPG45;SPG65;cN-II
Full Name
5'-nucleotidase, cytosolic II
Status
Confidence
Length
190421 bases
Strand
Minus strand
Position
10 : 103087185 - 103277605
RNA binding domain
N.A.
Summary
This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
30301969 Uncovering association networks through an eQTL analysis involving human miRNAs and lincRNAs.
R Paulo Branco
2018-10-09
Scientific reports
Name
Transcript ID
bp
Protein
Translation ID
NT5C2-220
ENST00000675164
4688
62aa
ENSP00000502128
NT5C2-201
ENST00000343289
3435
561aa
ENSP00000339479
NT5C2-203
ENST00000404739
3525
561aa
ENSP00000383960
NT5C2-218
ENST00000675020
3470
40aa
ENSP00000501653
NT5C2-217
ENST00000674860
3614
569aa
ENSP00000502816
NT5C2-227
ENST00000676449
3670
561aa
ENSP00000502801
NT5C2-216
ENST00000674728
4917
62aa
ENSP00000502126
NT5C2-226
ENST00000676428
3425
561aa
ENSP00000501689
NT5C2-225
ENST00000675985
3413
532aa
ENSP00000502215
NT5C2-224
ENST00000675811
3360
62aa
ENSP00000501901
NT5C2-202
ENST00000369857
3449
185aa
ENSP00000501806
NT5C2-219
ENST00000675040
3506
222aa
ENSP00000502090
NT5C2-222
ENST00000675436
3192
61aa
ENSP00000501565
NT5C2-215
ENST00000674696
3497
561aa
ENSP00000502679
NT5C2-221
ENST00000675326
3118
561aa
ENSP00000502205
NT5C2-223
ENST00000675645
2648
436aa
ENSP00000502663
NT5C2-204
ENST00000421281
440
146aa
ENSP00000408112
NT5C2-211
ENST00000470299
1099
44aa
ENSP00000474247
NT5C2-209
ENST00000469228
495
No protein
-
NT5C2-205
ENST00000452156
856
No protein
-
NT5C2-207
ENST00000461461
902
62aa
ENSP00000474091
NT5C2-206
ENST00000458345
597
No protein
-
NT5C2-210
ENST00000470228
891
No protein
-
NT5C2-214
ENST00000552185
642
157aa
ENSP00000447664
NT5C2-213
ENST00000487810
669
No protein
-
NT5C2-212
ENST00000481549
421
No protein
-
NT5C2-208
ENST00000467380
427
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
47167 Blood Pressure 1.0877043E-009 - 47184 Blood Pressure 9.7807699E-010 - 47186 Blood Pressure 9.6622541E-010 - 47196 Blood Pressure 9.4921686E-010 - 47197 Blood Pressure 9.5209571E-010 - 47198 Blood Pressure 9.4629709E-010 - 47199 Blood Pressure 9.1617112E-010 - 47200 Blood Pressure 9.0700257E-010 - 47201 Blood Pressure 5.4260482E-010 - 47202 Blood Pressure 5.8879226E-010 - 47204 Blood Pressure 9.8012115E-010 - 47205 Blood Pressure 5.9529603E-010 - 47207 Blood Pressure 9.6050446E-010 - 47208 Blood Pressure 9.6545244E-010 - 47214 Blood Pressure 8.4201565E-010 - 47271 Blood Pressure 2.8210722E-008 - 47285 Blood Pressure 2.5241975E-008 - 47286 Blood Pressure 2.4755783E-008 - 47294 Blood Pressure 2.4550256E-008 - 47295 Blood Pressure 2.4507710E-008 - 47296 Blood Pressure 2.4665816E-008 - 47297 Blood Pressure 2.1873595E-008 - 47298 Blood Pressure 2.4792600E-008 - 47299 Blood Pressure 1.8098952E-008 - 47300 Blood Pressure 1.7200827E-008 - 47302 Blood Pressure 2.5575614E-008 - 47303 Blood Pressure 1.7197746E-008 - 47304 Blood Pressure 2.4559822E-008 - 47305 Blood Pressure 2.4672286E-008 - 47350 Arterial Pressure 3.0738071E-009 - 47351 Arterial Pressure 1.8630748E-009 - 59273 Blood Pressure 1.9960000E-025 27618452 59287 Blood Pressure 5.2600000E-026 27618452 59290 Blood Pressure 1.2440000E-022 27618452 59293 Blood Pressure 1.9560000E-025 27618452 59304 Blood Pressure 1.0670000E-026 27618452 59305 Blood Pressure 1.5200000E-026 27618452 59306 Blood Pressure 2.6450000E-025 27618452 59307 Blood Pressure 1.2320000E-025 27618452 59308 Blood Pressure 3.2700000E-026 27618452 59309 Blood Pressure 8.8880000E-027 27618452 59310 Blood Pressure 8.3220000E-027 27618452 59311 Blood Pressure 6.1240000E-026 27618452 59313 Blood Pressure 1.3840000E-026 27618452 59314 Blood Pressure 1.7500000E-026 27618452 59694 Blood Pressure 5.6657645E-013 - 59797 Blood Pressure 2.5735122E-014 - 59863 Hypertension 1.7274104E-007 - 59952 Hypertension 1.6929482E-008 - 60062 Arterial Pressure 3.6369154E-010 - 60169 Arterial Pressure 8.5179839E-011 - 60259 Blood Pressure 1.1303859E-009 - 60367 Blood Pressure 4.5868149E-011 - 64547 Attention Deficit Disorder with Hyperactivity 1E-8 23453885 64548 Bipolar Disorder 1E-8 23453885 64549 Child Development Disorders, Pervasive 1E-8 23453885 64550 Depressive Disorder 1E-8 23453885 64551 Schizophrenia 1E-8 23453885 65894 Arterial Pressure 1E-15 21909110 69352 Body Mass Index 2E-9 25673413 73845 Schizophrenia 2E-9 22688191 74770 Arterial Pressure 1E-6 24001895 77493 Depressive Disorder 2E-6 27622933 77494 Citalopram 2E-6 27622933 77495 Mood Disorders 2E-6 27622933 79690 Schizophrenia 3E-8 21926974 82920 Body Mass Index 8E-9 25673413 88744 Body Mass Index 4E-8 24861553 103076 Arterial Pressure 2E-6 26390057 106147 Schizophrenia 2E-16 26198764
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000255 involved_in allantoin metabolic process 1 IDA Homo_sapiens(9606) Process GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005524 enables ATP binding 1 IDA Homo_sapiens(9606) Function GO:0005737 is_active_in cytoplasm 1 IDA Homo_sapiens(9606) Component GO:0005829 is_active_in cytosol 3 IDA,TAS Homo_sapiens(9606) Component GO:0006204 involved_in IMP catabolic process 1 IDA Homo_sapiens(9606) Process GO:0008253 enables 5-nucleotidase activity 3 IBA,IDA,ISS Homo_sapiens(9606) Function GO:0042802 enables identical protein binding 1 IDA Homo_sapiens(9606) Function GO:0046037 involved_in GMP metabolic process 1 IDA Homo_sapiens(9606) Process GO:0046040 involved_in IMP metabolic process 2 IBA,IDA Homo_sapiens(9606) Process GO:0046054 involved_in dGMP metabolic process 1 IDA Homo_sapiens(9606) Process GO:0046085 involved_in adenosine metabolic process 1 IBA Homo_sapiens(9606) Process GO:0046872 enables metal ion binding 1 IEA Homo_sapiens(9606) Function GO:0050146 enables nucleoside phosphotransferase activity 1 IDA Homo_sapiens(9606) Function GO:0050483 enables IMP 5-nucleotidase activity 1 IDA Homo_sapiens(9606) Function GO:0050484 enables GMP 5-nucleotidase activity 1 ISS Homo_sapiens(9606) Function GO:0050689 involved_in negative regulation of defense response to virus by host 1 IDA Homo_sapiens(9606) Process GO:0061630 enables ubiquitin protein ligase activity 1 IDA Homo_sapiens(9606) Function GO:0070936 involved_in protein K48-linked ubiquitination 1 IDA Homo_sapiens(9606) Process GO:0106411 enables XMP 5-nucleosidase activity 1 IEA Homo_sapiens(9606) Function
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