Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq

Description

Ensembl ID ENSG00000075702 Gene ID 284403 Accession 24502
Symbol WDR62 Alias MCPH2;C19orf14 Full Name WD repeat domain 62
Status Confidence Length 50228 bases Strand Plus strand
Position 19 : 36054881 - 36105108 RNA binding domain N.A.
Summary This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
WDR62-224 ENST00000680489 2987 No protein -
WDR62-202 ENST00000378860 1980 414aa ENSP00000504870
WDR62-204 ENST00000427823 1202 375aa ENSP00000413475
WDR62-235 ENST00000681542 1672 425aa ENSP00000505251
WDR62-219 ENST00000680321 1659 420aa ENSP00000505525
WDR62-208 ENST00000644764 1694 414aa ENSP00000494253
WDR62-221 ENST00000680359 1945 615aa ENSP00000506079
WDR62-223 ENST00000680403 4627 1434aa ENSP00000505677
WDR62-214 ENST00000679714 4708 1521aa ENSP00000506627
WDR62-213 ENST00000679682 4702 1518aa ENSP00000506226
WDR62-203 ENST00000401500 4727 1523aa ENSP00000384792
WDR62-225 ENST00000680564 4478 1440aa ENSP00000505582
WDR62-226 ENST00000680590 4655 515aa ENSP00000505350
WDR62-206 ENST00000589953 1902 No protein -
WDR62-240 ENST00000681809 1143 149aa ENSP00000505740
WDR62-215 ENST00000679757 4339 1406aa ENSP00000505158
WDR62-230 ENST00000680806 5159 425aa ENSP00000506418
WDR62-216 ENST00000679858 5020 319aa ENSP00000505655
WDR62-238 ENST00000681625 4610 882aa ENSP00000505555
WDR62-207 ENST00000608676 2976 No protein -
WDR62-205 ENST00000587391 5973 483aa ENSP00000465525
WDR62-201 ENST00000270301 4634 1518aa ENSP00000270301
WDR62-236 ENST00000681597 641 No protein -
WDR62-231 ENST00000680858 937 313aa ENSP00000505451
WDR62-222 ENST00000680377 1013 184aa ENSP00000505055
WDR62-234 ENST00000681302 1125 214aa ENSP00000505966
WDR62-211 ENST00000679489 464 91aa ENSP00000505399
WDR62-220 ENST00000680349 3298 No protein -
WDR62-233 ENST00000681088 882 210aa ENSP00000504920
WDR62-210 ENST00000679422 899 300aa ENSP00000505316
WDR62-209 ENST00000679357 2658 369aa ENSP00000506376
WDR62-229 ENST00000680773 3137 No protein -
WDR62-217 ENST00000680211 2066 390aa ENSP00000506102
WDR62-232 ENST00000680997 2545 No protein -
WDR62-237 ENST00000681608 2456 No protein -
WDR62-228 ENST00000680739 1667 91aa ENSP00000505170
WDR62-239 ENST00000681648 2672 No protein -
WDR62-218 ENST00000680280 2022 No protein -
WDR62-227 ENST00000680597 1385 72aa ENSP00000505037
WDR62-212 ENST00000679598 1397 313aa ENSP00000504936

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
59880Hypertension1.7292077E-006-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000922located_in spindle pole1IDAHomo_sapiens(9606)Component
GO:0002052involved_in positive regulation of neuroblast proliferation1IEAHomo_sapiens(9606)Process
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005813located_in centrosome1IDAHomo_sapiens(9606)Component
GO:0005814located_in centriole1IEAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0007052acts_upstream_of_or_within mitotic spindle organization1IMPHomo_sapiens(9606)Process
GO:0007099involved_in centriole replication2IBA,IMPHomo_sapiens(9606)Process
GO:0021987involved_in cerebral cortex development1IMPHomo_sapiens(9606)Process
GO:0022008involved_in neurogenesis1IMPHomo_sapiens(9606)Process
GO:0034451located_in centriolar satellite1IDAHomo_sapiens(9606)Component
GO:0045664involved_in regulation of neuron differentiation1IEAHomo_sapiens(9606)Process
GO:0046605involved_in regulation of centrosome cycle1IEAHomo_sapiens(9606)Process
GO:0072686is_active_in mitotic spindle1IBAHomo_sapiens(9606)Component
GO:2001224involved_in positive regulation of neuron migration1IEAHomo_sapiens(9606)Process

Expression