RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000075188	Gene ID	79023	Accession	29929
Symbol	NUP37	Alias	p37;MCPH24	Full Name	nucleoporin 37
Status	Confidence	Length	47018 bases	Strand	Minus strand
Position	12 : 102073103 - 102120120	RNA binding domain	N.A.
Summary	Nuclear pore complexes (NPCs) are used for transporting macromolecules between the cytoplasm and the nucleus. NPCs consist of multiple copies of 30 distinct proteins (nucleoporins), which assemble into biochemically-separable subcomplexes. The protein encoded by this gene is part of a subcomplex (Nup107-160) that is required for proper NPC function as well as for normal kinetochore-microtubule interaction and mitosis. [provided by RefSeq, Dec 2015]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
NUP37-209	ENST00000552283	2362	326aa	ENSP00000448054
NUP37-203	ENST00000546385	577	No protein	-
NUP37-204	ENST00000547269	798	31aa	ENSP00000447284
NUP37-208	ENST00000551744	762	208aa	ENSP00000448086
NUP37-207	ENST00000551200	1158	No protein	-
NUP37-202	ENST00000543021	784	No protein	-
NUP37-205	ENST00000548994	382	No protein	-
NUP37-206	ENST00000550459	645	51aa	ENSP00000449982
NUP37-201	ENST00000251074	1203	326aa	ENSP00000251074

Gene Model

Click here to download ENSG00000075188's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
4000	Triglycerides	1.41163568060184E-6	17903299
4030	Triglycerides	1.54693978947365E-6	17903299
7227	Alanine Transaminase	2.20482311824827E-6	17903293
10731	Hip	4.69603187036106E-7	17903296
69374	Body Height	8E-6	19893584
93555	Body Height	4E-46	25429064

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000075188's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000776	colocalizes_with kinetochore	1	IDA	Homo_sapiens(9606)	Component
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	HDA	Homo_sapiens(9606)	Component
GO:0005635	located_in nuclear envelope	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005643	part_of nuclear pore	1	NAS	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0006913	involved_in nucleocytoplasmic transport	1	NAS	Homo_sapiens(9606)	Process
GO:0007059	involved_in chromosome segregation	1	IEA	Homo_sapiens(9606)	Process
GO:0015031	involved_in protein transport	1	IEA	Homo_sapiens(9606)	Process
GO:0031080	part_of nuclear pore outer ring	3	IBA,IDA,NAS	Homo_sapiens(9606)	Component
GO:0051028	involved_in mRNA transport	1	IEA	Homo_sapiens(9606)	Process
GO:0051301	involved_in cell division	1	IEA	Homo_sapiens(9606)	Process

Expression