Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs ncRNA
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000072858 Gene ID 54847 Accession 25967
Symbol SIDT1 Alias SID1;SID-1 Full Name SID1 transmembrane family member 1
Status Confidence Length 97021 bases Strand Plus strand
Position 3 : 113532555 - 113629575 RNA binding domain SID-1_RNA_chan
Summary The protein encoded by this gene belongs to SID1 family of transmembrane dsRNA-gated channels. Family members transport dsRNA into cells and are required for systemic RNA interference. [provided by RefSeq, May 2017]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000264852 SID-1_RNA_chan PF13965 3.4e-294 1
ENSP00000377416 SID-1_RNA_chan PF13965 2.4e-292 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
SIDT1-201 ENST00000264852 4818 827aa ENSP00000264852
SIDT1-210 ENST00000491730 1645 No protein -
SIDT1-208 ENST00000483946 566 No protein -
SIDT1-209 ENST00000488390 648 No protein -
SIDT1-206 ENST00000480746 704 No protein -
SIDT1-205 ENST00000468728 361 No protein -
SIDT1-203 ENST00000463226 1471 No protein -
SIDT1-204 ENST00000465803 532 No protein -
SIDT1-211 ENST00000492863 733 No protein -
SIDT1-207 ENST00000481891 386 No protein -
SIDT1-212 ENST00000498152 577 No protein -
SIDT1-202 ENST00000393830 2572 832aa ENSP00000377416

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
62152Prostatic Neoplasms4E-1323535732
100076Dental Caries2E-623259602

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000072858homo_sapiensENSP0000031402372.956758.1731homo_sapiensENSP0000026485273.397858.5248

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000072858homo_sapiensENSP0000026485288.754588.7545nomascus_leucogenysENSNLEP0000002895098.921898.9218
ENSG00000072858homo_sapiensENSP0000026485290.931190.9311pan_paniscusENSPPAP0000003535399.208499.2084
ENSG00000072858homo_sapiensENSP0000026485299.879199.8791pongo_abeliiENSPPYP0000004551199.278899.2788
ENSG00000072858homo_sapiensENSP0000026485299.637299.6372pan_troglodytesENSPTRP0000007992699.038599.0385
ENSG00000072858homo_sapiensENSP0000026485299.637299.3954gorilla_gorillaENSGGOP0000001601199.038598.7981
ENSG00000072858homo_sapiensENSP0000026485282.466772.4305ornithorhynchus_anatinusENSOANP0000005260975.609866.408
ENSG00000072858homo_sapiensENSP0000026485292.140387.9081sarcophilus_harrisiiENSSHAP0000002852790.930886.7542
ENSG00000072858homo_sapiensENSP0000026485269.286666.1427notamacropus_eugeniiENSMEUP0000000403968.458865.3524
ENSG00000072858homo_sapiensENSP0000026485287.908185.4897choloepus_hoffmanniENSCHOP0000001110496.16493.5185
ENSG00000072858homo_sapiensENSP0000026485284.885180.8948dasypus_novemcinctusENSDNOP0000001536489.31385.1145
ENSG00000072858homo_sapiensENSP0000026485261.426858.8875erinaceus_europaeusENSEEUP0000001014166.405263.6601
ENSG00000072858homo_sapiensENSP0000026485279.08176.058echinops_telfairiENSETEP0000000154686.507983.2011
ENSG00000072858homo_sapiensENSP0000026485291.656688.8755callithrix_jacchusENSCJAP0000008689390.238187.5
ENSG00000072858homo_sapiensENSP0000026485298.669997.4607cercocebus_atysENSCATP0000002900198.076996.875
ENSG00000072858homo_sapiensENSP0000026485298.669997.9444macaca_fascicularisENSMFAP0000001617898.076997.3558
ENSG00000072858homo_sapiensENSP0000026485298.790898.0653macaca_mulattaENSMMUP0000001768798.197197.476
ENSG00000072858homo_sapiensENSP0000026485298.790898.0653macaca_nemestrinaENSMNEP0000002818598.197197.476
ENSG00000072858homo_sapiensENSP0000026485297.460795.8888papio_anubisENSPANP0000005450192.325390.8362
ENSG00000072858homo_sapiensENSP0000026485291.898490.8102mandrillus_leucophaeusENSMLEP0000001399297.938196.7784
ENSG00000072858homo_sapiensENSP0000026485292.019388.029tursiops_truncatusENSTTRP0000000026394.534290.4348
ENSG00000072858homo_sapiensENSP0000026485290.326587.1826vulpes_vulpesENSVVUP0000003026888.717385.6295
ENSG00000072858homo_sapiensENSP0000026485295.405191.6566mus_spretusMGP_SPRETEiJ_P004356494.831791.1058
ENSG00000072858homo_sapiensENSP0000026485292.744987.9081equus_asinusENSEASP0000501778793.082588.2282
ENSG00000072858homo_sapiensENSP0000026485294.195990.5683capra_hircusENSCHIP0000001629294.082190.4589
ENSG00000072858homo_sapiensENSP0000026485292.623988.6336loxodonta_africanaENSLAFP0000000792592.736188.7409
ENSG00000072858homo_sapiensENSP0000026485295.52691.8984panthera_leoENSPLOP0000001671195.410691.7874
ENSG00000072858homo_sapiensENSP0000026485286.215282.2249ailuropoda_melanoleucaENSAMEP0000003811685.287181.3397
ENSG00000072858homo_sapiensENSP0000026485294.800591.052bos_indicus_hybridENSBIXP0000500901394.68690.942
ENSG00000072858homo_sapiensENSP0000026485295.646993.2285oryctolagus_cuniculusENSOCUP0000000832096.581294.1392
ENSG00000072858homo_sapiensENSP0000026485292.744987.7872equus_caballusENSECAP0000007456393.082588.1068
ENSG00000072858homo_sapiensENSP0000026485294.316891.5357canis_lupus_familiarisENSCAFP0084504202994.775291.9806
ENSG00000072858homo_sapiensENSP0000026485295.52691.6566panthera_pardusENSPPRP0000002034895.410691.5459
ENSG00000072858homo_sapiensENSP0000026485293.228591.052marmota_marmota_marmotaENSMMMP0000001240195.895593.6567
ENSG00000072858homo_sapiensENSP0000026485295.163290.9311balaenoptera_musculusENSBMSP0001000202194.819390.6024
ENSG00000072858homo_sapiensENSP0000026485252.478851.3906cavia_porcellusENSCPOP0000002994197.747795.7207
ENSG00000072858homo_sapiensENSP0000026485295.767892.2612felis_catusENSFCAP0000003814595.652292.1498
ENSG00000072858homo_sapiensENSP0000026485287.061783.7969ursus_americanusENSUAMP0000003480291.02487.6106
ENSG00000072858homo_sapiensENSP0000026485283.675979.081monodelphis_domesticaENSMODP0000004468791.172686.166
ENSG00000072858homo_sapiensENSP0000026485292.382188.7545bison_bison_bisonENSBBBP0000000833293.627489.951
ENSG00000072858homo_sapiensENSP0000026485294.07589.9637monodon_monocerosENSMMNP0001501375294.188990.0726
ENSG00000072858homo_sapiensENSP0000026485295.767892.2612sus_scrofaENSSSCP0000001988095.652292.1498
ENSG00000072858homo_sapiensENSP0000026485297.460795.6469microcebus_murinusENSMICP0000005075197.108495.3012
ENSG00000072858homo_sapiensENSP0000026485253.204451.9952octodon_degusENSODEP0000000792599.099196.8468
ENSG00000072858homo_sapiensENSP0000026485278.839273.7606jaculus_jaculusENSJJAP0000000789989.192983.4473
ENSG00000072858homo_sapiensENSP0000026485294.437790.5683ovis_aries_rambouilletENSOARP0002000132594.323790.4589
ENSG00000072858homo_sapiensENSP0000026485285.489781.9831ursus_maritimusENSUMAP0000000544092.177388.3963
ENSG00000072858homo_sapiensENSP0000026485291.777588.5127ochotona_princepsENSOPRP0000001298991.777588.5127
ENSG00000072858homo_sapiensENSP0000026485294.195990.2056delphinapterus_leucasENSDLEP0000001643594.309990.3148
ENSG00000072858homo_sapiensENSP0000026485295.163291.4147physeter_catodonENSPCTP0000500206494.819391.0843
ENSG00000072858homo_sapiensENSP0000026485295.646991.8984mus_caroliMGP_CAROLIEiJ_P004168795.072191.3462
ENSG00000072858homo_sapiensENSP0000026485295.405191.6566mus_musculusENSMUSP0000003843394.831791.1058
ENSG00000072858homo_sapiensENSP0000026485251.511550.3023dipodomys_ordiiENSDORP0000000621899.300796.9697
ENSG00000072858homo_sapiensENSP0000026485294.921491.4147mustela_putorius_furoENSMPUP0000000028995.382791.8591
ENSG00000072858homo_sapiensENSP0000026485297.339895.7678aotus_nancymaaeENSANAP0000004055297.339895.7678
ENSG00000072858homo_sapiensENSP0000026485295.767893.954saimiri_boliviensis_boliviensisENSSBOP0000001840097.657295.8076
ENSG00000072858homo_sapiensENSP0000026485282.224978.9601vicugna_pacosENSVPAP0000001112092.140988.4824
ENSG00000072858homo_sapiensENSP0000026485298.911797.9444chlorocebus_sabaeusENSCSAP0000000306498.317397.3558
ENSG00000072858homo_sapiensENSP0000026485270.495867.3519tupaia_belangeriENSTBEP0000001343577.526674.0691
ENSG00000072858homo_sapiensENSP0000026485295.042392.2612mesocricetus_auratusENSMAUP0000002136894.471291.7067
ENSG00000072858homo_sapiensENSP0000026485294.316890.3265phocoena_sinusENSPSNP0000002305093.975990
ENSG00000072858homo_sapiensENSP0000026485295.284291.5357camelus_dromedariusENSCDRP0000502007195.169191.4251
ENSG00000072858homo_sapiensENSP0000026485287.545384.2805carlito_syrichtaENSTSYP0000003439290.274386.9077
ENSG00000072858homo_sapiensENSP0000026485292.382188.9964panthera_tigris_altaicaENSPTIP0000000680892.493989.1041
ENSG00000072858homo_sapiensENSP0000026485290.810286.4571rattus_norvegicusENSRNOP0000000275988.352984.1176
ENSG00000072858homo_sapiensENSP0000026485298.065396.1306prolemur_simusENSPSMP0000002082997.47695.5529
ENSG00000072858homo_sapiensENSP0000026485291.172987.1826microtus_ochrogasterENSMOCP0000002428292.40288.3578
ENSG00000072858homo_sapiensENSP0000026485246.553843.8936sorex_araneusENSSARP0000000985760.156256.7188
ENSG00000072858homo_sapiensENSP0000026485240.26639.1777sorex_araneusENSSARP0000000696761.100959.4495
ENSG00000072858homo_sapiensENSP0000026485295.163292.0193peromyscus_maniculatus_bairdiiENSPEMP0000003260694.591391.4663
ENSG00000072858homo_sapiensENSP0000026485288.149985.006bos_mutusENSBMUP0000002082196.174192.7441
ENSG00000072858homo_sapiensENSP0000026485295.52691.6566mus_spicilegusENSMSIP0000000438894.951991.1058
ENSG00000072858homo_sapiensENSP0000026485294.800591.8984cricetulus_griseus_chok1gshdENSCGRP0000102210694.230891.3462
ENSG00000072858homo_sapiensENSP0000026485289.721985.7316pteropus_vampyrusENSPVAP0000000581289.939485.9394
ENSG00000072858homo_sapiensENSP0000026485280.048473.2769myotis_lucifugusENSMLUP0000000388483.270476.2264
ENSG00000072858homo_sapiensENSP0000026485290.205685.7316vombatus_ursinusENSVURP0001001878889.234584.8086
ENSG00000072858homo_sapiensENSP0000026485295.042391.6566rhinolophus_ferrumequinumENSRFEP0001000175594.927591.5459
ENSG00000072858homo_sapiensENSP0000026485294.921491.052neovison_visonENSNVIP0000001805094.806890.942
ENSG00000072858homo_sapiensENSP0000026485294.800591.052bos_taurusENSBTAP0000001767895.261291.4945
ENSG00000072858homo_sapiensENSP0000026485296.130693.2285heterocephalus_glaber_femaleENSHGLP0000001694995.552992.6683
ENSG00000072858homo_sapiensENSP0000026485298.428197.7025rhinopithecus_bietiENSRBIP0000000650997.836597.1154
ENSG00000072858homo_sapiensENSP0000026485289.60187.0617canis_lupus_dingoENSCAFP0002000886791.368788.7793
ENSG00000072858homo_sapiensENSP0000026485297.097995.2842sciurus_vulgarisENSSVLP0000501174796.514494.7115
ENSG00000072858homo_sapiensENSP0000026485292.140387.9081phascolarctos_cinereusENSPCIP0000002644290.930886.7542
ENSG00000072858homo_sapiensENSP0000026485284.522480.7739procavia_capensisENSPCAP0000000423584.318580.579
ENSG00000072858homo_sapiensENSP0000026485295.52692.0193nannospalax_galiliENSNGAP0000000798195.641692.1308
ENSG00000072858homo_sapiensENSP0000026485294.800591.052bos_grunniensENSBGRP0000000217094.68690.942
ENSG00000072858homo_sapiensENSP0000026485293.228590.8102chinchilla_lanigeraENSCLAP0000001631196.981194.4654
ENSG00000072858homo_sapiensENSP0000026485294.316891.1729cervus_hanglu_yarkandensisENSCHYP0000003440294.202991.0628
ENSG00000072858homo_sapiensENSP0000026485295.284291.5357catagonus_wagneriENSCWAP0000002402295.169191.4251
ENSG00000072858homo_sapiensENSP0000026485296.130693.8331ictidomys_tridecemlineatusENSSTOP0000002819595.095792.823
ENSG00000072858homo_sapiensENSP0000026485289.4887.7872otolemur_garnettiiENSOGAP0000001000897.625395.7784
ENSG00000072858homo_sapiensENSP0000026485297.581695.8888cebus_imitatorENSCCAP0000001326797.581695.8888
ENSG00000072858homo_sapiensENSP0000026485295.888893.7122urocitellus_parryiiENSUPAP0001002476694.856592.7033
ENSG00000072858homo_sapiensENSP0000026485294.679691.6566moschus_moschiferusENSMMSP0000002663994.565291.5459
ENSG00000072858homo_sapiensENSP0000026485298.428197.5816rhinopithecus_roxellanaENSRROP0000003634097.836596.9952
ENSG00000072858homo_sapiensENSP0000026485295.646992.1403mus_pahariMGP_PahariEiJ_P002906895.072191.5865
ENSG00000072858homo_sapiensENSP0000026485289.359187.3035propithecus_coquereliENSPCOP0000002941597.109194.8752
ENSG00000072858homo_sapiensENSP0000026485237.484920.3144caenorhabditis_elegansC30E1.4.141.77922.6415
ENSG00000072858homo_sapiensENSP0000026485248.488532.1645caenorhabditis_elegansZK721.1.153.042335.1852
ENSG00000072858homo_sapiensENSP0000026485237.726720.3144caenorhabditis_elegansC08A9.3b.142.219222.7334
ENSG00000072858homo_sapiensENSP000002648528.222494.23216caenorhabditis_elegansF39F10.5.141.717821.4724
ENSG00000072858homo_sapiensENSP0000026485238.089521.0399caenorhabditis_elegansC04F5.1.140.592822.4227
ENSG00000072858homo_sapiensENSP0000026485243.28933.4946petromyzon_marinusENSPMAP0000000487881.54963.0979
ENSG00000072858homo_sapiensENSP0000026485266.747349.8186eptatretus_burgeriENSEBUP0000000782263.521347.4108
ENSG00000072858homo_sapiensENSP0000026485231.076227.8114callorhinchus_miliiENSCMIP0000002600290.175480.7018
ENSG00000072858homo_sapiensENSP0000026485226.481321.6445callorhinchus_miliiENSCMIP0000002599172.277259.0759
ENSG00000072858homo_sapiensENSP0000026485213.42210.2781callorhinchus_miliiENSCMIP0000002598158.115244.5026
ENSG00000072858homo_sapiensENSP0000026485278.234667.4728latimeria_chalumnaeENSLACP0000001571584.796973.1324
ENSG00000072858homo_sapiensENSP0000026485279.806566.8682lepisosteus_oculatusENSLOCP0000000345078.014265.3664
ENSG00000072858homo_sapiensENSP0000026485281.499467.7146xenopus_tropicalisENSXETP0000006476382.09568.2095
ENSG00000072858homo_sapiensENSP0000026485287.424480.4111chrysemys_picta_belliiENSCPBP0000000197787.108480.1205
ENSG00000072858homo_sapiensENSP0000026485284.038777.2672sphenodon_punctatusENSSPUP0000000762786.766579.7753
ENSG00000072858homo_sapiensENSP0000026485217.533315.5985crocodylus_porosusENSCPRP0000501371791.19581.1321
ENSG00000072858homo_sapiensENSP0000026485214.147512.6965laticauda_laticaudataENSLLTP0000001487787.969978.9474
ENSG00000072858homo_sapiensENSP0000026485259.975852.4788laticauda_laticaudataENSLLTP0000001456984.931574.3151
ENSG00000072858homo_sapiensENSP0000026485278.718369.5284notechis_scutatusENSNSUP0000002667882.300972.6928
ENSG00000072858homo_sapiensENSP0000026485280.169370.9794pseudonaja_textilisENSPTXP0000002107482.87573.375
ENSG00000072858homo_sapiensENSP0000026485287.182680.0484anas_platyrhynchos_platyrhynchosENSAPLP0000000684287.182680.0484
ENSG00000072858homo_sapiensENSP0000026485287.424480.1693gallus_gallusENSGALP0001003314488.063380.7552
ENSG00000072858homo_sapiensENSP0000026485284.159676.7836meleagris_gallopavoENSMGAP0000002581689.230881.4103
ENSG00000072858homo_sapiensENSP0000026485283.55575.4534serinus_canariaENSSCAP0000001543282.655574.6412
ENSG00000072858homo_sapiensENSP0000026485285.247977.63parus_majorENSPMJP0000001364981.691874.3917
ENSG00000072858homo_sapiensENSP0000026485284.280576.9045anolis_carolinensisENSACAP0000000658085.103877.6557
ENSG00000072858homo_sapiensENSP0000026485278.355569.6493naja_najaENSNNAP0000001480482.025372.9114
ENSG00000072858homo_sapiensENSP0000026485279.08171.705podarcis_muralisENSPMRP0000002727778.890271.532
ENSG00000072858homo_sapiensENSP0000026485283.796975.9371geospiza_fortisENSGFOP0000000143886.842178.6967
ENSG00000072858homo_sapiensENSP0000026485287.182680.0484taeniopygia_guttataENSTGUP0000003015088.034280.8303
ENSG00000072858homo_sapiensENSP0000026485269.770358.6457erpetoichthys_calabaricusENSECRP0000000660581.960268.892
ENSG00000072858homo_sapiensENSP0000026485279.927571.8259salvator_merianaeENSSMRP0000001415681.806973.5149
ENSG00000072858homo_sapiensENSP0000026485286.698980.532pelodiscus_sinensisENSPSIP0000001843788.191981.9188
ENSG00000072858homo_sapiensENSP0000026485281.499474.607gopherus_evgoodeiENSGEVP0000500350581.204874.3373
ENSG00000072858homo_sapiensENSP0000026485283.434176.2999chelonoidis_abingdoniiENSCABP0000002466585.820978.4826
ENSG00000072858homo_sapiensENSP0000026485284.159677.8718struthio_camelus_australisENSSCUP0000000643287.327580.803
ENSG00000072858homo_sapiensENSP0000026485284.764278.2346anser_brachyrhynchusENSABRP0000000400286.117979.484
ENSG00000072858homo_sapiensENSP0000026485287.666380.653strigops_habroptilaENSSHBP0000500933386.104579.2161
ENSG00000072858homo_sapiensENSP0000026485275.090768.4401terrapene_carolina_triunguisENSTMTP0000002369179.717672.6572
ENSG00000072858homo_sapiensENSP0000026485285.731678.4764aquila_chrysaetos_chrysaetosENSACCP0002002365485.421778.1928
ENSG00000072858homo_sapiensENSP0000026485228.29526.1185ficedula_albicollisENSFALP0000000533979.054172.973
ENSG00000072858homo_sapiensENSP0000026485221.039918.6215ficedula_albicollisENSFALP0000002368283.653874.0385
ENSG00000072858homo_sapiensENSP0000026485287.182679.4438coturnix_japonicaENSCJPP0000502150087.819780.0244
ENSG00000072858homo_sapiensENSP0000026485218.137813.6638leptobrachium_leishanenseENSLLEP0000003894578.53459.1623
ENSG00000072858homo_sapiensENSP0000026485252.841646.6747leptobrachium_leishanenseENSLLEP0000003849984.362974.5174

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003725enables double-stranded RNA binding1IBAHomo_sapiens(9606)Function
GO:0005764is_active_in lysosome1IBAHomo_sapiens(9606)Component
GO:0005886is_active_in plasma membrane1IBAHomo_sapiens(9606)Component
GO:0015485enables cholesterol binding1IDAHomo_sapiens(9606)Function
GO:0050658involved_in RNA transport1IBAHomo_sapiens(9606)Process
GO:0051033enables RNA transmembrane transporter activity1IBAHomo_sapiens(9606)Function

Expression