Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000072506 Gene ID 3028 Accession 4800
Symbol HSD17B10 Alias ABAD;CAMR;ERAB;HCD2;MHBD;HADH2;MRPP2;MRX17;MRX31;SCHAD;MRXS10;SDR5C1;HSD10MD;17b-HSD10;DUPXp11.22 Full Name hydroxysteroid 17-beta dehydrogenase 10
Status Confidence Length 3113 bases Strand Minus strand
Position X : 53431258 - 53434370 RNA binding domain N.A.
Summary This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
26632259 The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs. M Benedikt Beckmann 2015-12-03 Nature communications
35921164 The mitochondrial RNA granule modulates manganese-dependent cell toxicity. E Werner 2022-10-01 Molecular biology of the cell
32192199 Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment. Monika Schmidt 2020-03-17 International journal of molecular sciences
27132592 Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies. D Metodi Metodiev 2016-05-05 American journal of human genetics
29098073 Protein-mRNA interactome capture: cartography of the mRNP landscape. P Sean Ryder 2016-01-01 F1000Research
25575635 Mitochondrial energy failure in HSD10 disease is due to defective mtDNA transcript processing. C Kathryn Chatfield 2015-03-01 Mitochondrion
32859923 Defining the ATPome reveals cross-optimization of metabolic pathways. K Neal Bennett 2020-08-28 Nature communications

Transcripts

Name Transcript ID bp Protein Translation ID
HSD17B10-204 ENST00000477706 556 No protein -
HSD17B10-207 ENST00000684251 1060 No protein -
HSD17B10-203 ENST00000375304 916 252aa ENSP00000364453
HSD17B10-209 ENST00000684692 1154 217aa ENSP00000506792
HSD17B10-201 ENST00000168216 954 261aa ENSP00000168216
HSD17B10-202 ENST00000375298 823 169aa ENSP00000364447
HSD17B10-206 ENST00000682365 2663 No protein -
HSD17B10-205 ENST00000495986 901 No protein -
HSD17B10-208 ENST00000684503 856 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000072506homo_sapiensENSP0000033330026.333314homo_sapiensENSP0000016821630.268216.092
ENSG00000072506homo_sapiensENSP0000046679925.304917.0732homo_sapiensENSP0000016821631.800821.4559
ENSG00000072506homo_sapiensENSP0000045723017.391310.1449homo_sapiensENSP0000016821627.586216.092
ENSG00000072506homo_sapiensENSP0000026327836.666724.4444homo_sapiensENSP0000016821637.93125.2874
ENSG00000072506homo_sapiensENSP0000031678622.71613.3333homo_sapiensENSP0000016821635.24920.6897
ENSG00000072506homo_sapiensENSP0000025452124.926714.956homo_sapiensENSP0000016821632.567119.5402
ENSG00000072506homo_sapiensENSP000003510352715.3333homo_sapiensENSP0000016821631.034517.6245
ENSG00000072506homo_sapiensENSP0000036379451.34132.5671homo_sapiensENSP0000016821651.34132.5671
ENSG00000072506homo_sapiensENSP0000024028523.460415.5425homo_sapiensENSP0000016821630.651320.3065
ENSG00000072506homo_sapiensENSP0000048043924.172214.9007homo_sapiensENSP0000016821627.969317.2414
ENSG00000072506homo_sapiensENSP0000044907923.734215.5063homo_sapiensENSP0000016821628.735618.7739
ENSG00000072506homo_sapiensENSP0000036441225.806513.5484homo_sapiensENSP0000016821630.651316.092
ENSG00000072506homo_sapiensENSP0000037075023.899414.4654homo_sapiensENSP0000016821629.118817.6245
ENSG00000072506homo_sapiensENSP0000025789530.188721.6981homo_sapiensENSP0000016821636.781626.4368
ENSG00000072506homo_sapiensENSP0000030760725.566315.534homo_sapiensENSP0000016821630.268218.3908
ENSG00000072506homo_sapiensENSP0000027835326.602613.141homo_sapiensENSP0000016821631.800815.7088
ENSG00000072506homo_sapiensENSP0000019993625.839813.4367homo_sapiensENSP0000016821638.314219.9234
ENSG00000072506homo_sapiensENSP0000021943926.666713.0303homo_sapiensENSP0000016821633.716516.4751
ENSG00000072506homo_sapiensENSP0000042494014.5389.375homo_sapiensENSP0000016821640.996226.4368
ENSG00000072506homo_sapiensENSP0000037618428.279914.5773homo_sapiensENSP0000016821637.164719.1571
ENSG00000072506homo_sapiensENSP0000041156523.880611.5672homo_sapiensENSP0000016821624.521111.8774
ENSG00000072506homo_sapiensENSP0000029350230.670917.8914homo_sapiensENSP0000016821636.781621.4559
ENSG00000072506homo_sapiensENSP0000031863126.813917.0347homo_sapiensENSP0000016821632.567120.6897
ENSG00000072506homo_sapiensENSP0000050239929.153618.4953homo_sapiensENSP0000016821635.632222.6054
ENSG00000072506homo_sapiensENSP0000038120630.283920.1893homo_sapiensENSP0000016821636.781624.5211

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000072506homo_sapiensENSP0000016821698.084397.318nomascus_leucogenysENSNLEP0000001941898.084397.318
ENSG00000072506homo_sapiensENSP00000168216100100pan_paniscusENSPPAP00000018768100100
ENSG00000072506homo_sapiensENSP0000016821698.084397.318pongo_abeliiENSPPYP0000002280898.084397.318
ENSG00000072506homo_sapiensENSP00000168216100100pan_troglodytesENSPTRP00000037656100100
ENSG00000072506homo_sapiensENSP0000016821699.616999.2337gorilla_gorillaENSGGOP0000002094399.616999.2337
ENSG00000072506homo_sapiensENSP0000016821699.616999.2337gorilla_gorillaENSGGOP0000002201499.616999.2337
ENSG00000072506homo_sapiensENSP0000016821686.5977.7778ornithorhynchus_anatinusENSOANP0000003782186.923178.0769
ENSG00000072506homo_sapiensENSP0000016821681.609270.8812sarcophilus_harrisiiENSSHAP0000000680665.740757.0988
ENSG00000072506homo_sapiensENSP0000016821681.609273.9464notamacropus_eugeniiENSMEUP0000000781785.542277.51
ENSG00000072506homo_sapiensENSP0000016821641.762535.6322choloepus_hoffmanniENSCHOP0000000906282.575870.4545
ENSG00000072506homo_sapiensENSP0000016821686.973280.4598choloepus_hoffmanniENSCHOP0000000083488.671982.0312
ENSG00000072506homo_sapiensENSP0000016821691.95488.5057dasypus_novemcinctusENSDNOP0000000373291.95488.5057
ENSG00000072506homo_sapiensENSP0000016821685.823881.2261dasypus_novemcinctusENSDNOP0000000682588.888984.127
ENSG00000072506homo_sapiensENSP0000016821694.252988.8889erinaceus_europaeusENSEEUP0000000463194.252988.8889
ENSG00000072506homo_sapiensENSP0000016821692.720388.8889echinops_telfairiENSETEP0000001352092.720388.8889
ENSG00000072506homo_sapiensENSP0000016821696.934995.4023callithrix_jacchusENSCJAP0000005951196.934995.4023
ENSG00000072506homo_sapiensENSP0000016821697.701197.318cercocebus_atysENSCATP0000002238097.701197.318
ENSG00000072506homo_sapiensENSP0000016821697.701196.9349macaca_fascicularisENSMFAP0000002086497.701196.9349
ENSG00000072506homo_sapiensENSP0000016821697.701197.318macaca_mulattaENSMMUP0000004104797.701197.318
ENSG00000072506homo_sapiensENSP0000016821697.31896.9349macaca_nemestrinaENSMNEP0000001868897.31896.9349
ENSG00000072506homo_sapiensENSP0000016821697.701197.318papio_anubisENSPANP0000001015497.701197.318
ENSG00000072506homo_sapiensENSP0000016821697.701197.318mandrillus_leucophaeusENSMLEP0000002709497.701197.318
ENSG00000072506homo_sapiensENSP0000016821694.252991.954tursiops_truncatusENSTTRP0000001085495.348893.0233
ENSG00000072506homo_sapiensENSP0000016821694.63691.954vulpes_vulpesENSVVUP0000004203792.857190.2256
ENSG00000072506homo_sapiensENSP0000016821693.486686.59mus_spretusMGP_SPRETEiJ_P009684090.036983.3948
ENSG00000072506homo_sapiensENSP0000016821694.252991.1877equus_asinusENSEASP0000504747494.252991.1877
ENSG00000072506homo_sapiensENSP0000016821695.785491.1877capra_hircusENSCHIP0000001778295.785491.1877
ENSG00000072506homo_sapiensENSP0000016821694.63691.954loxodonta_africanaENSLAFP0000002395691.143988.5609
ENSG00000072506homo_sapiensENSP0000016821657.854449.8084panthera_leoENSPLOP0000000396458.076950
ENSG00000072506homo_sapiensENSP0000016821694.252991.1877ailuropoda_melanoleucaENSAMEP0000000532794.252991.1877
ENSG00000072506homo_sapiensENSP0000016821693.486689.6552bos_indicus_hybridENSBIXP0000500722984.722281.25
ENSG00000072506homo_sapiensENSP0000016821693.103489.272oryctolagus_cuniculusENSOCUP0000001541163.446560.8355
ENSG00000072506homo_sapiensENSP0000016821694.252991.1877canis_lupus_familiarisENSCAFP0084504067794.252991.1877
ENSG00000072506homo_sapiensENSP0000016821652.107347.1264panthera_pardusENSPPRP0000000214780.473472.7811
ENSG00000072506homo_sapiensENSP0000016821673.946472.0307marmota_marmota_marmotaENSMMMP0000001447890.610388.2629
ENSG00000072506homo_sapiensENSP0000016821696.168693.8697balaenoptera_musculusENSBMSP0001002430996.168693.8697
ENSG00000072506homo_sapiensENSP0000016821694.63691.5709cavia_porcellusENSCPOP0000003075794.63691.5709
ENSG00000072506homo_sapiensENSP0000016821693.486690.8046felis_catusENSFCAP0000005259890.706388.1041
ENSG00000072506homo_sapiensENSP0000016821694.252991.1877ursus_americanusENSUAMP0000003088094.252991.1877
ENSG00000072506homo_sapiensENSP0000016821683.141872.4138monodelphis_domesticaENSMODP0000005819974.061464.5051
ENSG00000072506homo_sapiensENSP0000016821695.785491.954bison_bison_bisonENSBBBP0000002291895.785491.954
ENSG00000072506homo_sapiensENSP0000016821695.785493.4866monodon_monocerosENSMMNP0001502061895.785493.4866
ENSG00000072506homo_sapiensENSP0000016821694.252990.8046sus_scrofaENSSSCP0000002963783.95980.8874
ENSG00000072506homo_sapiensENSP0000016821695.785492.7203microcebus_murinusENSMICP0000001321695.785492.7203
ENSG00000072506homo_sapiensENSP0000016821694.252989.6552octodon_degusENSODEP0000002702494.252989.6552
ENSG00000072506homo_sapiensENSP0000016821679.693572.7969octodon_degusENSODEP0000001312588.888981.1966
ENSG00000072506homo_sapiensENSP0000016821669.731864.3678octodon_degusENSODEP0000001442486.255979.6208
ENSG00000072506homo_sapiensENSP0000016821693.103488.1226octodon_degusENSODEP0000002633993.103488.1226
ENSG00000072506homo_sapiensENSP0000016821694.63690.4215octodon_degusENSODEP0000001445994.63690.4215
ENSG00000072506homo_sapiensENSP0000016821675.095870.1149jaculus_jaculusENSJJAP0000001982587.111181.3333
ENSG00000072506homo_sapiensENSP0000016821695.785490.8046jaculus_jaculusENSJJAP0000001049695.785490.8046
ENSG00000072506homo_sapiensENSP0000016821695.785491.954ovis_aries_rambouilletENSOARP0002001150395.785491.954
ENSG00000072506homo_sapiensENSP0000016821692.337289.272ursus_maritimusENSUMAP0000002616681.972879.2517
ENSG00000072506homo_sapiensENSP0000016821669.731867.433ochotona_princepsENSOPRP0000000018591.919288.8889
ENSG00000072506homo_sapiensENSP0000016821695.785493.4866delphinapterus_leucasENSDLEP0000001311995.785493.4866
ENSG00000072506homo_sapiensENSP0000016821696.168693.4866physeter_catodonENSPCTP0000502076896.168693.4866
ENSG00000072506homo_sapiensENSP0000016821693.486686.9732mus_caroliMGP_CAROLIEiJ_P009307690.036983.7638
ENSG00000072506homo_sapiensENSP0000016821693.869786.9732mus_musculusENSMUSP0000010823690.405983.7638
ENSG00000072506homo_sapiensENSP0000016821672.413867.8161dipodomys_ordiiENSDORP0000002140974.409469.685
ENSG00000072506homo_sapiensENSP0000016821691.187788.1226dipodomys_ordiiENSDORP0000000378391.187788.1226
ENSG00000072506homo_sapiensENSP0000016821693.486689.6552mustela_putorius_furoENSMPUP0000000968093.486689.6552
ENSG00000072506homo_sapiensENSP0000016821697.701195.4023aotus_nancymaaeENSANAP0000002137697.701195.4023
ENSG00000072506homo_sapiensENSP0000016821696.934995.4023saimiri_boliviensis_boliviensisENSSBOP0000002088596.934995.4023
ENSG00000072506homo_sapiensENSP0000016821676.245273.5632vicugna_pacosENSVPAP0000000299776.245273.5632
ENSG00000072506homo_sapiensENSP0000016821697.701197.318chlorocebus_sabaeusENSCSAP0000000873197.701197.318
ENSG00000072506homo_sapiensENSP0000016821694.63690.8046tupaia_belangeriENSTBEP0000001516294.63690.8046
ENSG00000072506homo_sapiensENSP0000016821695.019291.5709mesocricetus_auratusENSMAUP0000001276495.019291.5709
ENSG00000072506homo_sapiensENSP0000016821695.785493.1034phocoena_sinusENSPSNP0000002254995.785493.1034
ENSG00000072506homo_sapiensENSP0000016821695.785492.3372camelus_dromedariusENSCDRP0000502996695.785492.3372
ENSG00000072506homo_sapiensENSP0000016821695.402391.954carlito_syrichtaENSTSYP0000000489595.402391.954
ENSG00000072506homo_sapiensENSP0000016821695.402392.3372panthera_tigris_altaicaENSPTIP0000000685895.402392.3372
ENSG00000072506homo_sapiensENSP0000016821692.720385.4406rattus_norvegicusENSRNOP0000009515085.512478.7986
ENSG00000072506homo_sapiensENSP0000016821685.823881.9923prolemur_simusENSPSMP0000003097490.688386.6397
ENSG00000072506homo_sapiensENSP0000016821696.934993.8697prolemur_simusENSPSMP0000002622596.934993.8697
ENSG00000072506homo_sapiensENSP0000016821694.63690.4215microtus_ochrogasterENSMOCP0000000051994.63690.4215
ENSG00000072506homo_sapiensENSP0000016821650.957947.1264microtus_ochrogasterENSMOCP0000000732279.166773.2143
ENSG00000072506homo_sapiensENSP0000016821661.302756.705sorex_araneusENSSARP0000000646161.068756.4885
ENSG00000072506homo_sapiensENSP0000016821695.785492.3372peromyscus_maniculatus_bairdiiENSPEMP0000001740395.785492.3372
ENSG00000072506homo_sapiensENSP0000016821695.785491.5709bos_mutusENSBMUP0000002619795.785491.5709
ENSG00000072506homo_sapiensENSP0000016821695.785491.5709cricetulus_griseus_chok1gshdENSCGRP0000102081895.785491.5709
ENSG00000072506homo_sapiensENSP0000016821693.486690.0383pteropus_vampyrusENSPVAP0000000178893.486690.0383
ENSG00000072506homo_sapiensENSP0000016821694.252989.272myotis_lucifugusENSMLUP0000000015994.252989.272
ENSG00000072506homo_sapiensENSP0000016821689.655282.3755myotis_lucifugusENSMLUP0000000342689.655282.3755
ENSG00000072506homo_sapiensENSP0000016821681.992373.9464vombatus_ursinusENSVURP0001002765639.85135.9404
ENSG00000072506homo_sapiensENSP0000016821677.777872.0307rhinolophus_ferrumequinumENSRFEP0001000314077.186371.4829
ENSG00000072506homo_sapiensENSP0000016821667.43362.4521neovison_visonENSNVIP0000001692177.19371.4912
ENSG00000072506homo_sapiensENSP0000016821695.785491.954bos_taurusENSBTAP0000002364295.785491.954
ENSG00000072506homo_sapiensENSP0000016821691.570986.59heterocephalus_glaber_femaleENSHGLP0000000210281.292576.8708
ENSG00000072506homo_sapiensENSP0000016821697.701196.9349rhinopithecus_bietiENSRBIP0000000157697.701196.9349
ENSG00000072506homo_sapiensENSP0000016821694.252991.1877canis_lupus_dingoENSCAFP0002002531194.252991.1877
ENSG00000072506homo_sapiensENSP0000016821694.63691.5709sciurus_vulgarisENSSVLP0000501805094.63691.5709
ENSG00000072506homo_sapiensENSP0000016821681.609273.9464phascolarctos_cinereusENSPCIP0000001693681.923174.2308
ENSG00000072506homo_sapiensENSP0000016821665.134163.6015procavia_capensisENSPCAP0000000440695.505693.2584
ENSG00000072506homo_sapiensENSP0000016821693.869790.8046nannospalax_galiliENSNGAP0000001737893.869790.8046
ENSG00000072506homo_sapiensENSP0000016821695.019290.8046bos_grunniensENSBGRP0000004146795.752991.5058
ENSG00000072506homo_sapiensENSP0000016821693.869790.4215chinchilla_lanigeraENSCLAP0000000929293.869790.4215
ENSG00000072506homo_sapiensENSP0000016821695.785491.5709cervus_hanglu_yarkandensisENSCHYP0000002464495.785491.5709
ENSG00000072506homo_sapiensENSP0000016821693.103489.272catagonus_wagneriENSCWAP0000000587893.103489.272
ENSG00000072506homo_sapiensENSP0000016821695.402393.4866ictidomys_tridecemlineatusENSSTOP0000000494295.402393.4866
ENSG00000072506homo_sapiensENSP0000016821695.785492.7203otolemur_garnettiiENSOGAP0000000264195.785492.7203
ENSG00000072506homo_sapiensENSP0000016821697.31895.4023cebus_imitatorENSCCAP0000002694497.31895.4023
ENSG00000072506homo_sapiensENSP0000016821695.402393.1034urocitellus_parryiiENSUPAP0001000086195.402393.1034
ENSG00000072506homo_sapiensENSP0000016821695.402391.5709moschus_moschiferusENSMMSP0000000753595.402391.5709
ENSG00000072506homo_sapiensENSP0000016821697.701196.9349rhinopithecus_roxellanaENSRROP0000001693597.701196.9349
ENSG00000072506homo_sapiensENSP0000016821693.869786.9732mus_pahariMGP_PahariEiJ_P009068690.405983.7638
ENSG00000072506homo_sapiensENSP0000016821696.551793.1034propithecus_coquereliENSPCOP0000001225096.551793.1034
ENSG00000072506homo_sapiensENSP0000016821670.881257.8544caenorhabditis_elegansF01G4.2a.171.705458.5271
ENSG00000072506homo_sapiensENSP0000016821676.628365.9004drosophila_melanogasterFBpp007428578.431467.451
ENSG00000072506homo_sapiensENSP0000016821663.984746.3602ciona_intestinalisENSCINP0000000697361.851944.8148
ENSG00000072506homo_sapiensENSP0000016821676.628366.6667ciona_intestinalisENSCINP0000000398876.335966.4122
ENSG00000072506homo_sapiensENSP0000016821649.042144.4444petromyzon_marinusENSPMAP0000000634690.140881.6901
ENSG00000072506homo_sapiensENSP0000016821681.992370.8812eptatretus_burgeriENSEBUP0000002449282.307771.1538
ENSG00000072506homo_sapiensENSP0000016821684.291275.8621latimeria_chalumnaeENSLACP0000001752484.615476.1538
ENSG00000072506homo_sapiensENSP0000016821681.609272.7969clupea_harengusENSCHAP0000003024281.923173.0769
ENSG00000072506homo_sapiensENSP0000016821681.609272.0307danio_rerioENSDARP0000001759781.923172.3077
ENSG00000072506homo_sapiensENSP0000016821669.348756.705carassius_auratusENSCARP0000012226373.877560.4082
ENSG00000072506homo_sapiensENSP0000016821681.992372.7969carassius_auratusENSCARP0000007902582.307773.0769
ENSG00000072506homo_sapiensENSP0000016821683.524972.7969astyanax_mexicanusENSAMXP0000005334883.846273.0769
ENSG00000072506homo_sapiensENSP0000016821681.609272.7969ictalurus_punctatusENSIPUP0000001904081.923173.0769
ENSG00000072506homo_sapiensENSP0000016821681.609271.2644esox_luciusENSELUP0000002276281.923171.5385
ENSG00000072506homo_sapiensENSP0000016821682.375572.7969electrophorus_electricusENSEEEP0000001156582.692373.0769
ENSG00000072506homo_sapiensENSP0000016821681.226171.2644oncorhynchus_kisutchENSOKIP0000501551781.538571.5385
ENSG00000072506homo_sapiensENSP0000016821681.226171.2644oncorhynchus_mykissENSOMYP0000001780881.538571.5385
ENSG00000072506homo_sapiensENSP0000016821681.226171.2644salmo_salarENSSSAP0000014380671.621662.8378
ENSG00000072506homo_sapiensENSP0000016821681.226171.2644salmo_truttaENSSTUP0000003108281.538571.5385
ENSG00000072506homo_sapiensENSP0000016821683.141872.0307fundulus_heteroclitusENSFHEP0000000963583.461572.3077
ENSG00000072506homo_sapiensENSP0000016821680.842970.1149poecilia_reticulataENSPREP0000003028181.153870.3846
ENSG00000072506homo_sapiensENSP0000016821650.957940.9962xiphophorus_maculatusENSXMAP0000003173645.392536.5188
ENSG00000072506homo_sapiensENSP0000016821650.191639.8467xiphophorus_maculatusENSXMAP0000003586940.683232.2981
ENSG00000072506homo_sapiensENSP0000016821683.141872.7969oryzias_latipesENSORLP0000003266583.461573.0769
ENSG00000072506homo_sapiensENSP0000016821677.394667.8161cyclopterus_lumpusENSCLMP0000503015477.692368.0769
ENSG00000072506homo_sapiensENSP0000016821672.413861.3027cyclopterus_lumpusENSCLMP0000503014969.485358.8235
ENSG00000072506homo_sapiensENSP0000016821684.291273.1801oreochromis_niloticusENSONIP0000002993784.615473.4615
ENSG00000072506homo_sapiensENSP0000016821683.90872.7969haplochromis_burtoniENSHBUP0000000832284.230873.0769
ENSG00000072506homo_sapiensENSP0000016821683.90872.7969astatotilapia_callipteraENSACLP0000002237884.230873.0769
ENSG00000072506homo_sapiensENSP0000016821682.758671.6475sparus_aurataENSSAUP0001002392683.076971.9231
ENSG00000072506homo_sapiensENSP0000016821683.141872.7969lates_calcariferENSLCAP0001004823980.370470.3704
ENSG00000072506homo_sapiensENSP0000016821683.90874.3295xenopus_tropicalisENSXETP0000011428070.41862.3794
ENSG00000072506homo_sapiensENSP0000016821683.90876.6283chrysemys_picta_belliiENSCPBP0000002325283.90876.6283
ENSG00000072506homo_sapiensENSP0000016821681.609270.8812laticauda_laticaudataENSLLTP0000002461781.609270.8812
ENSG00000072506homo_sapiensENSP0000016821681.992371.2644notechis_scutatusENSNSUP0000002041981.992371.2644
ENSG00000072506homo_sapiensENSP0000016821681.226170.4981pseudonaja_textilisENSPTXP0000000673581.226170.4981
ENSG00000072506homo_sapiensENSP0000016821681.992370.4981gallus_gallusENSGALP0001000039350.831443.7055
ENSG00000072506homo_sapiensENSP0000016821672.413861.6858meleagris_gallopavoENSMGAP0000000788980.769268.8034
ENSG00000072506homo_sapiensENSP0000016821644.827639.0805parus_majorENSPMJP0000000437760.937553.125
ENSG00000072506homo_sapiensENSP0000016821653.639850.1916anolis_carolinensisENSACAP0000002864082.352977.0588
ENSG00000072506homo_sapiensENSP0000016821661.685855.9387neolamprologus_brichardiENSNBRP0000001551788.950380.663
ENSG00000072506homo_sapiensENSP0000016821680.459870.1149naja_najaENSNNAP0000002929380.459870.1149
ENSG00000072506homo_sapiensENSP0000016821685.440679.3103podarcis_muralisENSPMRP0000003670385.440679.3103
ENSG00000072506homo_sapiensENSP0000016821647.892738.3142podarcis_muralisENSPMRP0000000206772.674458.1395
ENSG00000072506homo_sapiensENSP0000016821670.498159.0038taeniopygia_guttataENSTGUP0000002505076.666764.1667
ENSG00000072506homo_sapiensENSP0000016821681.992370.8812taeniopygia_guttataENSTGUP0000001579674.048464.0138
ENSG00000072506homo_sapiensENSP0000016821682.375572.7969erpetoichthys_calabaricusENSECRP0000001357577.338168.3453
ENSG00000072506homo_sapiensENSP0000016821682.758671.6475kryptolebias_marmoratusENSKMAP0000002620583.076971.9231
ENSG00000072506homo_sapiensENSP0000016821685.057577.7778salvator_merianaeENSSMRP0000002004984.090976.8939
ENSG00000072506homo_sapiensENSP0000016821683.141873.1801oryzias_javanicusENSOJAP0000002652180.669171.0037
ENSG00000072506homo_sapiensENSP0000016821683.90873.5632amphilophus_citrinellusENSACIP0000000572477.112767.6056
ENSG00000072506homo_sapiensENSP0000016821682.758672.7969dicentrarchus_labraxENSDLAP0000508307677.419468.1004
ENSG00000072506homo_sapiensENSP0000016821670.881256.3218amphiprion_perculaENSAPEP0000002909474.297259.0361
ENSG00000072506homo_sapiensENSP0000016821682.758672.7969oryzias_sinensisENSOSIP0000000336683.076973.0769
ENSG00000072506homo_sapiensENSP0000016821683.141875.8621gopherus_evgoodeiENSGEVP0000502789371.617265.3465
ENSG00000072506homo_sapiensENSP0000016821684.291276.6283chelonoidis_abingdoniiENSCABP0000002000584.291276.6283
ENSG00000072506homo_sapiensENSP0000016821683.90872.7969seriola_dumeriliENSSDUP0000000848884.230873.0769
ENSG00000072506homo_sapiensENSP0000016821679.693568.1992cottoperca_gobioENSCGOP0000002645783.534171.4859
ENSG00000072506homo_sapiensENSP0000016821628.352516.4751anser_brachyrhynchusENSABRP0000000937628.352516.4751
ENSG00000072506homo_sapiensENSP0000016821658.620748.659anser_brachyrhynchusENSABRP0000002696357.735847.9245
ENSG00000072506homo_sapiensENSP0000016821683.524973.1801gasterosteus_aculeatusENSGACP0000001393983.524973.1801
ENSG00000072506homo_sapiensENSP0000016821682.758672.0307cynoglossus_semilaevisENSCSEP0000001403983.076972.3077
ENSG00000072506homo_sapiensENSP0000016821681.226170.8812poecilia_formosaENSPFOP0000001097081.538571.1538
ENSG00000072506homo_sapiensENSP0000016821682.758672.4138myripristis_murdjanENSMMDP0000502967483.076972.6923
ENSG00000072506homo_sapiensENSP0000016821682.758672.7969sander_luciopercaENSSLUP0000005696483.076973.0769
ENSG00000072506homo_sapiensENSP0000016821680.076669.3487strigops_habroptilaENSSHBP0000500946177.985167.5373
ENSG00000072506homo_sapiensENSP0000016821654.406146.7433terrapene_carolina_triunguisENSTMTP0000002687178.888967.7778
ENSG00000072506homo_sapiensENSP0000016821682.375571.2644betta_splendensENSBSLP0000001968982.061170.9924
ENSG00000072506homo_sapiensENSP0000016821681.609273.5632pygocentrus_nattereriENSPNAP0000000659581.923173.8462
ENSG00000072506homo_sapiensENSP0000016821683.141873.1801anabas_testudineusENSATEP0000003592083.461573.4615
ENSG00000072506homo_sapiensENSP0000016821675.095866.2835ciona_savignyiENSCSAVP0000001046774.809266.0305
ENSG00000072506homo_sapiensENSP0000016821683.90872.7969seriola_lalandi_dorsalisENSSLDP0000000329484.230873.0769
ENSG00000072506homo_sapiensENSP0000016821673.946463.2184labrus_bergyltaENSLBEP0000002851769.927559.7826
ENSG00000072506homo_sapiensENSP0000016821669.348758.6207labrus_bergyltaENSLBEP0000000356060.942851.5152
ENSG00000072506homo_sapiensENSP0000016821669.348760.1533labrus_bergyltaENSLBEP0000002838480.444469.7778
ENSG00000072506homo_sapiensENSP0000016821681.992372.0307labrus_bergyltaENSLBEP0000001763985.25974.9004
ENSG00000072506homo_sapiensENSP0000016821650.191642.1456labrus_bergyltaENSLBEP0000001249179.393966.6667
ENSG00000072506homo_sapiensENSP0000016821669.348759.0038labrus_bergyltaENSLBEP0000001796370.703160.1562
ENSG00000072506homo_sapiensENSP0000016821642.145634.0996labrus_bergyltaENSLBEP0000002219674.324360.1351
ENSG00000072506homo_sapiensENSP0000016821680.459870.8812labrus_bergyltaENSLBEP0000001506083.665373.7052
ENSG00000072506homo_sapiensENSP0000016821645.97738.6973labrus_bergyltaENSLBEP0000000684475.471763.522
ENSG00000072506homo_sapiensENSP0000016821649.425340.613labrus_bergyltaENSLBEP0000003873270.491857.9235
ENSG00000072506homo_sapiensENSP0000016821667.816158.6207labrus_bergyltaENSLBEP0000000537971.37161.6936
ENSG00000072506homo_sapiensENSP0000016821683.524973.1801labrus_bergyltaENSLBEP0000000973183.846273.4615
ENSG00000072506homo_sapiensENSP0000016821646.360238.6973labrus_bergyltaENSLBEP0000002607677.070164.3312
ENSG00000072506homo_sapiensENSP0000016821681.992372.0307labrus_bergyltaENSLBEP0000001604285.25974.9004
ENSG00000072506homo_sapiensENSP0000016821677.011567.433labrus_bergyltaENSLBEP0000001884181.048470.9677
ENSG00000072506homo_sapiensENSP0000016821674.329563.9847labrus_bergyltaENSLBEP0000003042582.203470.7627
ENSG00000072506homo_sapiensENSP0000016821684.291272.4138pundamilia_nyerereiENSPNYP0000002996884.615472.6923
ENSG00000072506homo_sapiensENSP0000016821683.524973.1801mastacembelus_armatusENSMAMP0000005590083.846273.4615
ENSG00000072506homo_sapiensENSP0000016821683.141871.6475stegastes_partitusENSSPAP0000000816783.461571.9231
ENSG00000072506homo_sapiensENSP0000016821647.509639.0805oncorhynchus_tshawytschaENSOTSP0000502178277.018663.354
ENSG00000072506homo_sapiensENSP0000016821683.141872.4138acanthochromis_polyacanthusENSAPOP0000002795078.057667.9856
ENSG00000072506homo_sapiensENSP0000016821681.226170.8812aquila_chrysaetos_chrysaetosENSACCP0002002441081.538571.1538
ENSG00000072506homo_sapiensENSP0000016821684.291273.1801nothobranchius_furzeriENSNFUP0001504232886.956575.4941
ENSG00000072506homo_sapiensENSP0000016821684.291272.7969cyprinodon_variegatusENSCVAP0000002542684.615473.0769
ENSG00000072506homo_sapiensENSP0000016821683.141872.7969denticeps_clupeoidesENSDCDP0000005451983.461573.0769
ENSG00000072506homo_sapiensENSP0000016821683.524973.1801larimichthys_croceaENSLCRP0000502707763.742755.848
ENSG00000072506homo_sapiensENSP0000016821681.992370.8812hippocampus_comesENSHCOP0000001249881.992370.8812
ENSG00000072506homo_sapiensENSP0000016821681.609272.4138cyprinus_carpio_carpioENSCCRP0000016928676.344167.7419
ENSG00000072506homo_sapiensENSP0000016821681.226170.8812poecilia_latipinnaENSPLAP0000001689981.538571.1538
ENSG00000072506homo_sapiensENSP0000016821681.609272.4138sinocyclocheilus_grahamiENSSGRP0000002541481.923172.6923
ENSG00000072506homo_sapiensENSP0000016821681.992372.7969sinocyclocheilus_grahamiENSSGRP0000004408382.307773.0769
ENSG00000072506homo_sapiensENSP0000016821684.291273.1801maylandia_zebraENSMZEP0000503576384.615473.4615
ENSG00000072506homo_sapiensENSP0000016821683.141871.2644tetraodon_nigroviridisENSTNIP0000001537483.141871.2644
ENSG00000072506homo_sapiensENSP0000016821683.90873.1801paramormyrops_kingsleyaeENSPKIP0000002123166.163157.7039
ENSG00000072506homo_sapiensENSP0000016821683.141873.9464scleropages_formosusENSSFOP0001501896283.461574.2308
ENSG00000072506homo_sapiensENSP0000016821682.375575.0958leptobrachium_leishanenseENSLLEP0000001901982.692375.3846
ENSG00000072506homo_sapiensENSP0000016821683.524972.4138scophthalmus_maximusENSSMAP0000002951083.846272.6923
ENSG00000072506homo_sapiensENSP0000016821683.141873.1801oryzias_melastigmaENSOMEP0000001252377.568.2143

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000049enables tRNA binding1IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003857enables 3-hydroxyacyl-CoA dehydrogenase activity1IDAHomo_sapiens(9606)Function
GO:0004303enables estradiol 17-beta-dehydrogenase [NAD(P)] activity1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737located_in cytoplasm1TASHomo_sapiens(9606)Component
GO:0005739is_active_in mitochondrion3IBA,IDA,ISSHomo_sapiens(9606)Component
GO:0005759located_in mitochondrial matrix1TASHomo_sapiens(9606)Component
GO:0005886located_in plasma membrane1TASHomo_sapiens(9606)Component
GO:0006550involved_in isoleucine catabolic process2IDA,IEAHomo_sapiens(9606)Process
GO:0006629involved_in lipid metabolic process1TASHomo_sapiens(9606)Process
GO:0006631involved_in fatty acid metabolic process1IBAHomo_sapiens(9606)Process
GO:0006635involved_in fatty acid beta-oxidation2IDA,IEAHomo_sapiens(9606)Process
GO:0006699involved_in bile acid biosynthetic process2IDA,IEAHomo_sapiens(9606)Process
GO:0007005involved_in mitochondrion organization1IMPHomo_sapiens(9606)Process
GO:0008207involved_in C21-steroid hormone metabolic process1IDAHomo_sapiens(9606)Process
GO:0008209involved_in androgen metabolic process2IBA,IDAHomo_sapiens(9606)Process
GO:0008210involved_in estrogen metabolic process2IBA,IDAHomo_sapiens(9606)Process
GO:0008709enables cholate 7-alpha-dehydrogenase activity1IDAHomo_sapiens(9606)Function
GO:0030283enables testosterone dehydrogenase [NAD(P)] activity1IDAHomo_sapiens(9606)Function
GO:0030678part_of mitochondrial ribonuclease P complex3IDA,IPI,TASHomo_sapiens(9606)Component
GO:0042645located_in mitochondrial nucleoid1IDAHomo_sapiens(9606)Component
GO:0043527part_of tRNA methyltransferase complex1IPIHomo_sapiens(9606)Component
GO:0044594enables 17-beta-hydroxysteroid dehydrogenase (NAD+) activity1IDAHomo_sapiens(9606)Function
GO:0047015enables 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity1IDAHomo_sapiens(9606)Function
GO:0047035enables testosterone dehydrogenase (NAD+) activity1IDAHomo_sapiens(9606)Function
GO:0047044enables androstan-3-alpha,17-beta-diol dehydrogenase activity1IEAHomo_sapiens(9606)Function
GO:0051289involved_in protein homotetramerization1IDAHomo_sapiens(9606)Process
GO:0062173involved_in brexanolone metabolic process1IDAHomo_sapiens(9606)Process
GO:0070901involved_in mitochondrial tRNA methylation1IDAHomo_sapiens(9606)Process
GO:0097745involved_in mitochondrial tRNA 5-end processing1IDAHomo_sapiens(9606)Process
GO:0106281enables chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity1IDAHomo_sapiens(9606)Function
GO:0106282enables isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity1IDAHomo_sapiens(9606)Function
GO:0106283enables ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity1IDAHomo_sapiens(9606)Function
GO:1990180involved_in mitochondrial tRNA 3-end processing1IDAHomo_sapiens(9606)Process

Expression