RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000072042	Gene ID	51109	Accession	17964
Symbol	RDH11	Alias	MDT1;CGI82;PSDR1;RALR1;SCALD;ARSDR1;HCBP12;RDJCSS;SDR7C1	Full Name	retinol dehydrogenase 11
Status	Confidence	Length	18975 bases	Strand	Minus strand
Position	14 : 67676800 - 67695774	RNA binding domain	N.A.
Summary	Enables NADP-retinol dehydrogenase activity. Involved in cellular detoxification of aldehyde and retinoid metabolic process. Acts upstream of or within retinal metabolic process. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
RDH11-201	ENST00000381346	2539	318aa	ENSP00000370750
RDH11-203	ENST00000553384	1926	305aa	ENSP00000452079
RDH11-204	ENST00000553578	4035	No protein	-
RDH11-202	ENST00000428130	1064	248aa	ENSP00000416395
RDH11-207	ENST00000554731	888	61aa	ENSP00000451280
RDH11-206	ENST00000554035	849	204aa	ENSP00000450802
RDH11-205	ENST00000553816	1163	No protein	-
RDH11-209	ENST00000557273	562	178aa	ENSP00000450651
RDH11-211	ENST00000557726	621	186aa	ENSP00000450435
RDH11-210	ENST00000557331	553	62aa	ENSP00000452108
RDH11-208	ENST00000556692	801	No protein	-

Gene Model

Click here to download ENSG00000072042's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000072042's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001523	involved_in retinoid metabolic process	2	IDA,TAS	Homo_sapiens(9606)	Process
GO:0001917	located_in photoreceptor inner segment	1	IEA	Homo_sapiens(9606)	Component
GO:0004745	enables NAD-retinol dehydrogenase activity	2	ISS,TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005789	located_in endoplasmic reticulum membrane	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0007601	involved_in visual perception	1	IEA	Homo_sapiens(9606)	Process
GO:0016062	involved_in adaptation of rhodopsin mediated signaling	1	IEA	Homo_sapiens(9606)	Process
GO:0016616	enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1	TAS	Homo_sapiens(9606)	Function
GO:0033721	enables aldehyde dehydrogenase (NADP+) activity	1	IEA	Homo_sapiens(9606)	Function
GO:0042572	involved_in retinol metabolic process	2	IEA,ISS	Homo_sapiens(9606)	Process
GO:0042574	acts_upstream_of_or_within retinal metabolic process	1	IDA	Homo_sapiens(9606)	Process
GO:0052650	enables NADP-retinol dehydrogenase activity	2	IDA,TAS	Homo_sapiens(9606)	Function
GO:0102354	enables 11-cis-retinol dehydrogenase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0110095	involved_in cellular detoxification of aldehyde	1	IDA	Homo_sapiens(9606)	Process

Expression