RBP Type
Canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
TF
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000065526 Gene ID
23013 Accession
17575
Symbol
SPEN
Alias
MINT;SHARP;RATARS;RBM15C;HIAA0929
Full Name
spen family transcriptional repressor
Status
Confidence
Length
104362 bases
Strand
Plus strand
Position
1 : 15836095 - 15940456
RNA binding domain
RRM_5 , RRM_1
Summary
This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000364912
RRM_1
PF00076 1.7e-42
1
ENSP00000364912
RRM_1
PF00076 1.7e-42
2
ENSP00000364912
RRM_1
PF00076 1.7e-42
3
ENSP00000364912
RRM_1
PF00076 1.7e-42
4
ENSP00000364912
RRM_5
PF13893 2.2e-06
5
ENSP00000364912
RRM_5
PF13893 2.2e-06
6
ENSP00000501122
RRM_1
PF00076 2.9e-31
1
ENSP00000501122
RRM_1
PF00076 2.9e-31
2
ENSP00000501122
RRM_1
PF00076 2.9e-31
3
ENSP00000501122
RRM_5
PF13893 2.7e-07
4
ENSP00000501122
RRM_5
PF13893 2.7e-07
5
ENSP00000400914
RRM_1
PF00076 2.3e-25
1
ENSP00000400914
RRM_1
PF00076 2.3e-25
2
ENSP00000388021
RRM_1
PF00076 1.3e-12
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
21037582 GRLD-1 regulates cell-wide abundance of glutamate receptor through post-transcriptional regulation.
J George Wang
2010-12-01
Nature neuroscience
26575292 Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.
Li Zhang
2015-11-17
eLife
30347781 Local Tandem Repeat Expansion in Xist RNA as a Model for the Functionalisation of ncRNA.
Neil Brockdorff
2018-10-19
Non-coding RNA
19586903 The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1.
Hiroaki Uranishi
2009-09-18
The Journal of biological chemistry
34418791 Recent insights into the role of glia and oxidative stress in Alzheimer's disease gained from Drosophila.
D Lindsey Goodman
2022-02-01
Current opinion in neurobiology
36077510 Transcriptional Regulation of Endogenous Retroviruses and Their Misregulation in Human Diseases.
Qian Zhang
2022-09-04
International journal of molecular sciences
36725318 Targeting RNA with small molecules: lessons learned from Xist RNA.
B Elliott Nickbarg
2023-04-01
RNA (New York, N.Y.)
24748666 The crystal structure of the Split End protein SHARP adds a new layer of complexity to proteins containing RNA recognition motifs.
Fabiana Arieti
2014-06-01
Nucleic acids research
33208773 Spen modulates lipid droplet content in adult Drosophila glial cells and protects against paraquat toxicity.
Victor Girard
2020-11-18
Scientific reports
Name
Transcript ID
bp
Protein
Translation ID
SPEN-206
ENST00000673875
3123
704aa
ENSP00000501122
SPEN-201
ENST00000375759
12385
3664aa
ENSP00000364912
SPEN-202
ENST00000438066
13500
135aa
ENSP00000388021
SPEN-204
ENST00000471538
1404
No protein
-
SPEN-203
ENST00000442985
891
297aa
ENSP00000400914
SPEN-207
ENST00000704274
8040
2170aa
ENSP00000515812
SPEN-205
ENST00000487496
543
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
15586 Heart Failure 4.9030685E-004 -
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000065526 homo_sapiens ENSP00000343966 41.8738 23.9006 homo_sapiens ENSP00000364912 5.97707 3.41157 ENSG00000065526 homo_sapiens ENSP00000276079 46.7091 26.7516 homo_sapiens ENSP00000364912 6.00437 3.43886 ENSG00000065526 homo_sapiens ENSP00000294428 37.3372 19.8263 homo_sapiens ENSP00000364912 7.04148 3.73908 ENSG00000065526 homo_sapiens ENSP00000454545 40.3371 24.6067 homo_sapiens ENSP00000364912 9.79803 5.97707 ENSG00000065526 homo_sapiens ENSP00000358799 41.8628 25.6909 homo_sapiens ENSP00000364912 11.1627 6.85044 ENSG00000065526 homo_sapiens ENSP00000482277 38.9716 22.0568 homo_sapiens ENSP00000364912 7.86026 4.44869 ENSG00000065526 homo_sapiens ENSP00000349748 33.9463 18.6704 homo_sapiens ENSP00000364912 6.55022 3.60262
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000065526 homo_sapiens ENSP00000364912 97.6801 97.107 nomascus_leucogenys ENSNLEP00000009306 97.7335 97.16 ENSG00000065526 homo_sapiens ENSP00000364912 98.2533 98.0076 pan_paniscus ENSPPAP00000025118 98.7383 98.4915 ENSG00000065526 homo_sapiens ENSP00000364912 99.3723 98.9902 pongo_abelii ENSPPYP00000002129 99.4265 99.0442 ENSG00000065526 homo_sapiens ENSP00000364912 99.6725 99.4814 pan_troglodytes ENSPTRP00000000386 99.7269 99.5358 ENSG00000065526 homo_sapiens ENSP00000364912 98.6081 98.2806 gorilla_gorilla ENSGGOP00000011754 98.6619 98.3342 ENSG00000065526 homo_sapiens ENSP00000364912 78.3297 69.9782 ornithorhynchus_anatinus ENSOANP00000044310 76.9231 68.7215 ENSG00000065526 homo_sapiens ENSP00000364912 77.9749 69.405 sarcophilus_harrisii ENSSHAP00000035298 78.3813 69.7668 ENSG00000065526 homo_sapiens ENSP00000364912 69.6234 61.5175 notamacropus_eugenii ENSMEUP00000002223 72.9691 64.4737 ENSG00000065526 homo_sapiens ENSP00000364912 91.1026 87.8548 dasypus_novemcinctus ENSDNOP00000028665 91.1773 87.9268 ENSG00000065526 homo_sapiens ENSP00000364912 60.8079 57.1779 erinaceus_europaeus ENSEEUP00000009383 65.2034 61.3111 ENSG00000065526 homo_sapiens ENSP00000364912 58.1059 55.4312 echinops_telfairi ENSETEP00000013547 60.3287 57.5517 ENSG00000065526 homo_sapiens ENSP00000364912 97.2162 95.8788 callithrix_jacchus ENSCJAP00000046060 97.349 96.0098 ENSG00000065526 homo_sapiens ENSP00000364912 98.4443 97.8439 cercocebus_atys ENSCATP00000004203 98.2031 97.6041 ENSG00000065526 homo_sapiens ENSP00000364912 97.7893 97.1889 macaca_fascicularis ENSMFAP00000029423 96.1363 95.546 ENSG00000065526 homo_sapiens ENSP00000364912 97.5164 96.8341 macaca_mulatta ENSMMUP00000010529 96.6459 95.9697 ENSG00000065526 homo_sapiens ENSP00000364912 98.3624 97.762 macaca_nemestrina ENSMNEP00000038851 98.1214 97.5225 ENSG00000065526 homo_sapiens ENSP00000364912 97.9803 97.4072 papio_anubis ENSPANP00000031451 97.9803 97.4072 ENSG00000065526 homo_sapiens ENSP00000364912 97.5164 96.8614 mandrillus_leucophaeus ENSMLEP00000030196 97.4366 96.7821 ENSG00000065526 homo_sapiens ENSP00000364912 73.226 70.7151 tursiops_truncatus ENSTTRP00000014881 73.973 71.4364 ENSG00000065526 homo_sapiens ENSP00000364912 92.0579 88.7009 vulpes_vulpes ENSVVUP00000040638 91.6825 88.3392 ENSG00000065526 homo_sapiens ENSP00000364912 86.4629 81.0044 mus_spretus MGP_SPRETEiJ_P0068154 86.9613 81.4713 ENSG00000065526 homo_sapiens ENSP00000364912 4.3941 4.12118 equus_asinus ENSEASP00005051715 94.7059 88.8235 ENSG00000065526 homo_sapiens ENSP00000364912 19.4869 19.1321 equus_asinus ENSEASP00005044597 97.4079 95.6344 ENSG00000065526 homo_sapiens ENSP00000364912 61.3264 59.0611 equus_asinus ENSEASP00005023371 90.0601 86.7335 ENSG00000065526 homo_sapiens ENSP00000364912 92.0852 87.9913 capra_hircus ENSCHIP00000030257 92.3372 88.2321 ENSG00000065526 homo_sapiens ENSP00000364912 90.4203 87.0633 loxodonta_africana ENSLAFP00000003776 90.371 87.0158 ENSG00000065526 homo_sapiens ENSP00000364912 92.1943 89.0011 panthera_leo ENSPLOP00000006608 91.8434 88.6623 ENSG00000065526 homo_sapiens ENSP00000364912 89.9836 86.9814 ailuropoda_melanoleuca ENSAMEP00000012429 91.4563 88.405 ENSG00000065526 homo_sapiens ENSP00000364912 92.0852 88.1277 bos_indicus_hybrid ENSBIXP00005006711 92.5906 88.6114 ENSG00000065526 homo_sapiens ENSP00000364912 87.7183 83.952 oryctolagus_cuniculus ENSOCUP00000039198 89.2778 85.4444 ENSG00000065526 homo_sapiens ENSP00000364912 4.3941 4.12118 equus_caballus ENSECAP00000071549 94.7059 88.8235 ENSG00000065526 homo_sapiens ENSP00000364912 85.2347 82.2325 equus_caballus ENSECAP00000030912 91.4495 88.2284 ENSG00000065526 homo_sapiens ENSP00000364912 87.7729 84.4432 canis_lupus_familiaris ENSCAFP00845006955 91.3636 87.8977 ENSG00000065526 homo_sapiens ENSP00000364912 92.2216 89.1648 balaenoptera_musculus ENSBMSP00010000003 93.0085 89.9257 ENSG00000065526 homo_sapiens ENSP00000364912 85.262 81.3865 cavia_porcellus ENSCPOP00000021991 90.3935 86.2847 ENSG00000065526 homo_sapiens ENSP00000364912 92.1124 88.8646 felis_catus ENSFCAP00000059566 91.7618 88.5264 ENSG00000065526 homo_sapiens ENSP00000364912 92.3854 89.3013 ursus_americanus ENSUAMP00000011829 92.1339 89.0583 ENSG00000065526 homo_sapiens ENSP00000364912 78.0841 69.214 monodelphis_domestica ENSMODP00000031808 80.8192 71.6384 ENSG00000065526 homo_sapiens ENSP00000364912 89.0557 85.0437 bison_bison_bison ENSBBBP00000007503 92.1491 87.9977 ENSG00000065526 homo_sapiens ENSP00000364912 91.9487 88.9465 monodon_monoceros ENSMMNP00015012688 92.6568 89.6315 ENSG00000065526 homo_sapiens ENSP00000364912 92.9039 90.4749 microcebus_murinus ENSMICP00000036382 92.7773 90.3516 ENSG00000065526 homo_sapiens ENSP00000364912 86.6812 82.56 octodon_degus ENSODEP00000022673 90.7688 86.4533 ENSG00000065526 homo_sapiens ENSP00000364912 88.1823 84.0611 jaculus_jaculus ENSJJAP00000006173 89.6753 85.4843 ENSG00000065526 homo_sapiens ENSP00000364912 92.1124 88.1004 ovis_aries_rambouillet ENSOARP00020020796 92.5672 88.5354 ENSG00000065526 homo_sapiens ENSP00000364912 90.8843 87.691 ursus_maritimus ENSUMAP00000029932 91.2829 88.0757 ENSG00000065526 homo_sapiens ENSP00000364912 81.6048 77.702 ochotona_princeps ENSOPRP00000014460 82.5739 78.6247 ENSG00000065526 homo_sapiens ENSP00000364912 91.8395 88.8919 delphinapterus_leucas ENSDLEP00000019171 92.6487 89.6751 ENSG00000065526 homo_sapiens ENSP00000364912 92.0579 89.1376 physeter_catodon ENSPCTP00005001005 92.6648 89.7253 ENSG00000065526 homo_sapiens ENSP00000364912 86.2991 81.0044 mus_caroli MGP_CAROLIEiJ_P0065596 87.0116 81.6731 ENSG00000065526 homo_sapiens ENSP00000364912 86.4356 80.9498 mus_musculus ENSMUSP00000101412 86.9338 81.4164 ENSG00000065526 homo_sapiens ENSP00000364912 84.9618 79.8308 dipodomys_ordii ENSDORP00000026524 88.7653 83.4046 ENSG00000065526 homo_sapiens ENSP00000364912 89.8745 86.4629 mustela_putorius_furo ENSMPUP00000016214 91.1179 87.6591 ENSG00000065526 homo_sapiens ENSP00000364912 96.1245 94.9782 aotus_nancymaae ENSANAP00000033540 95.7586 94.6166 ENSG00000065526 homo_sapiens ENSP00000364912 92.9858 91.7849 saimiri_boliviensis_boliviensis ENSSBOP00000024583 96.1886 94.9464 ENSG00000065526 homo_sapiens ENSP00000364912 98.2533 97.571 chlorocebus_sabaeus ENSCSAP00000017165 98.0926 97.4114 ENSG00000065526 homo_sapiens ENSP00000364912 68.5317 66.6485 tupaia_belangeri ENSTBEP00000003182 69.1355 67.2357 ENSG00000065526 homo_sapiens ENSP00000364912 84.9891 80.1037 mesocricetus_auratus ENSMAUP00000006437 87.991 82.933 ENSG00000065526 homo_sapiens ENSP00000364912 92.0033 88.8919 phocoena_sinus ENSPSNP00000000029 92.7628 89.6258 ENSG00000065526 homo_sapiens ENSP00000364912 92.7129 89.738 camelus_dromedarius ENSCDRP00005004846 92.7382 89.7625 ENSG00000065526 homo_sapiens ENSP00000364912 85.1801 82.4236 carlito_syrichta ENSTSYP00000023898 93.1364 90.1224 ENSG00000065526 homo_sapiens ENSP00000364912 85.9989 80.4585 rattus_norvegicus ENSRNOP00000052647 86.7805 81.1898 ENSG00000065526 homo_sapiens ENSP00000364912 92.6583 90.1201 prolemur_simus ENSPSMP00000009629 92.5068 89.9728 ENSG00000065526 homo_sapiens ENSP00000364912 87.2817 82.4782 microtus_ochrogaster ENSMOCP00000017511 88.2694 83.4115 ENSG00000065526 homo_sapiens ENSP00000364912 87.691 82.833 peromyscus_maniculatus_bairdii ENSPEMP00000027091 88.1481 83.2647 ENSG00000065526 homo_sapiens ENSP00000364912 90.0928 86.0535 bos_mutus ENSBMUP00000034251 92.1295 87.9989 ENSG00000065526 homo_sapiens ENSP00000364912 86.4629 80.9498 mus_spicilegus ENSMSIP00000016586 87.6834 82.0924 ENSG00000065526 homo_sapiens ENSP00000364912 86.6266 81.8504 cricetulus_griseus_chok1gshd ENSCGRP00001005844 87.7766 82.937 ENSG00000065526 homo_sapiens ENSP00000364912 75.7369 73.417 pteropus_vampyrus ENSPVAP00000013011 76.1108 73.7795 ENSG00000065526 homo_sapiens ENSP00000364912 85.3166 81.6048 myotis_lucifugus ENSMLUP00000009294 89.4421 85.5508 ENSG00000065526 homo_sapiens ENSP00000364912 77.0197 68.095 vombatus_ursinus ENSVURP00010001308 80.4218 71.1029 ENSG00000065526 homo_sapiens ENSP00000364912 92.4127 89.3286 rhinolophus_ferrumequinum ENSRFEP00010016600 92.4127 89.3286 ENSG00000065526 homo_sapiens ENSP00000364912 91.8395 88.4552 neovison_vison ENSNVIP00000015048 91.3905 88.0228 ENSG00000065526 homo_sapiens ENSP00000364912 91.7303 87.8275 bos_taurus ENSBTAP00000053545 92.3352 88.4066 ENSG00000065526 homo_sapiens ENSP00000364912 90.9662 87.1725 heterocephalus_glaber_female ENSHGLP00000029924 90.8174 87.03 ENSG00000065526 homo_sapiens ENSP00000364912 96.6703 95.9061 rhinopithecus_bieti ENSRBIP00000031671 97.0943 96.3268 ENSG00000065526 homo_sapiens ENSP00000364912 68.095 64.9836 canis_lupus_dingo ENSCAFP00020005992 88.9483 84.8841 ENSG00000065526 homo_sapiens ENSP00000364912 3.6845 3.6845 canis_lupus_dingo ENSCAFP00020005990 41.5385 41.5385 ENSG00000065526 homo_sapiens ENSP00000364912 90.7478 87.2544 sciurus_vulgaris ENSSVLP00005013102 91.1458 87.6371 ENSG00000065526 homo_sapiens ENSP00000364912 5.5131 5.34935 phascolarctos_cinereus ENSPCIP00000020988 45.1902 43.8479 ENSG00000065526 homo_sapiens ENSP00000364912 79.8035 76.3373 procavia_capensis ENSPCAP00000008929 82.6689 79.0783 ENSG00000065526 homo_sapiens ENSP00000364912 84.4705 81.0044 nannospalax_galili ENSNGAP00000000890 90.2596 86.5558 ENSG00000065526 homo_sapiens ENSP00000364912 91.6485 87.5819 bos_grunniens ENSBGRP00000029242 90.7077 86.6829 ENSG00000065526 homo_sapiens ENSP00000364912 85.6168 81.9596 chinchilla_lanigera ENSCLAP00000002800 91.298 87.3981 ENSG00000065526 homo_sapiens ENSP00000364912 92.1943 88.3734 cervus_hanglu_yarkandensis ENSCHYP00000033751 92.4973 88.6637 ENSG00000065526 homo_sapiens ENSP00000364912 89.6561 86.1081 catagonus_wagneri ENSCWAP00000014837 91.5552 87.932 ENSG00000065526 homo_sapiens ENSP00000364912 89.5469 86.0535 ictidomys_tridecemlineatus ENSSTOP00000023742 91.2656 87.7051 ENSG00000065526 homo_sapiens ENSP00000364912 93.1769 90.0928 otolemur_garnettii ENSOGAP00000017035 93.1006 90.0191 ENSG00000065526 homo_sapiens ENSP00000364912 92.6037 90.8024 cebus_imitator ENSCCAP00000005143 95.0686 93.2194 ENSG00000065526 homo_sapiens ENSP00000364912 91.4847 88.0186 urocitellus_parryii ENSUPAP00010022760 91.7853 88.3078 ENSG00000065526 homo_sapiens ENSP00000364912 87.7456 83.8155 moschus_moschiferus ENSMMSP00000010137 91.2316 87.1453 ENSG00000065526 homo_sapiens ENSP00000364912 97.0797 96.2609 rhinopithecus_roxellana ENSRROP00000023713 97.1062 96.2872 ENSG00000065526 homo_sapiens ENSP00000364912 86.0808 80.4858 mus_pahari MGP_PahariEiJ_P0080682 86.7675 81.1279 ENSG00000065526 homo_sapiens ENSP00000364912 92.4672 89.9563 propithecus_coquereli ENSPCOP00000019578 93.3591 90.8239 ENSG00000065526 homo_sapiens ENSP00000364912 42.2489 26.2555 drosophila_melanogaster FBpp0077781 27.8417 17.3022 ENSG00000065526 homo_sapiens ENSP00000364912 4.83079 3.82096 eptatretus_burgeri ENSEBUP00000008439 61.4583 48.6111 ENSG00000065526 homo_sapiens ENSP00000364912 60.262 48.417 callorhinchus_milii ENSCMIP00000036123 56.7026 45.5573 ENSG00000065526 homo_sapiens ENSP00000364912 72.8166 61.8996 latimeria_chalumnae ENSLACP00000003657 73.9058 62.8255 ENSG00000065526 homo_sapiens ENSP00000364912 65.8297 54.2576 lepisosteus_oculatus ENSLOCP00000009591 67.0932 55.299 ENSG00000065526 homo_sapiens ENSP00000364912 60.8352 47.5983 clupea_harengus ENSCHAP00000058590 62.1584 48.6336 ENSG00000065526 homo_sapiens ENSP00000364912 58.679 45.6332 danio_rerio ENSDARP00000098999 61.8527 48.1013 ENSG00000065526 homo_sapiens ENSP00000364912 55.7587 44.3504 carassius_auratus ENSCARP00000045992 58.3048 46.3756 ENSG00000065526 homo_sapiens ENSP00000364912 58.7336 46.0972 carassius_auratus ENSCARP00000130848 61.6266 48.3677 ENSG00000065526 homo_sapiens ENSP00000364912 58.2151 45.5513 astyanax_mexicanus ENSAMXP00000042817 59.8653 46.8425 ENSG00000065526 homo_sapiens ENSP00000364912 59.5524 46.179 ictalurus_punctatus ENSIPUP00000032222 63.0818 48.9159 ENSG00000065526 homo_sapiens ENSP00000364912 3.46616 3.27511 electrophorus_electricus ENSEEEP00000029944 94.0741 88.8889 ENSG00000065526 homo_sapiens ENSP00000364912 3.98472 3.35699 electrophorus_electricus ENSEEEP00000029950 73 61.5 ENSG00000065526 homo_sapiens ENSP00000364912 57.1779 44.6507 oncorhynchus_kisutch ENSOKIP00005070777 59.1307 46.1756 ENSG00000065526 homo_sapiens ENSP00000364912 45.6878 33.0513 oncorhynchus_kisutch ENSOKIP00005066630 58.1452 42.0632 ENSG00000065526 homo_sapiens ENSP00000364912 61.1081 47.0797 oncorhynchus_mykiss ENSOMYP00000096611 63.338 48.7977 ENSG00000065526 homo_sapiens ENSP00000364912 53.7391 41.2391 oncorhynchus_mykiss ENSOMYP00000087909 55.418 42.5274 ENSG00000065526 homo_sapiens ENSP00000364912 61.19 46.9432 salmo_salar ENSSSAP00000113559 63.244 48.519 ENSG00000065526 homo_sapiens ENSP00000364912 57.9967 45.3603 salmo_salar ENSSSAP00000156241 59.6073 46.6199 ENSG00000065526 homo_sapiens ENSP00000364912 57.9694 45.3876 salmo_trutta ENSSTUP00000044448 59.6294 46.6873 ENSG00000065526 homo_sapiens ENSP00000364912 61.2172 46.9978 salmo_trutta ENSSTUP00000031722 63.3079 48.6029 ENSG00000065526 homo_sapiens ENSP00000364912 53.9574 41.8395 gadus_morhua ENSGMOP00000036092 56.518 43.825 ENSG00000065526 homo_sapiens ENSP00000364912 44.5415 32.0142 fundulus_heteroclitus ENSFHEP00000011674 55.5291 39.9115 ENSG00000065526 homo_sapiens ENSP00000364912 6.87773 6.00437 fundulus_heteroclitus ENSFHEP00000011696 74.1176 64.7059 ENSG00000065526 homo_sapiens ENSP00000364912 58.2696 44.5688 poecilia_reticulata ENSPREP00000015415 60.533 46.3 ENSG00000065526 homo_sapiens ENSP00000364912 57.9694 44.2959 xiphophorus_maculatus ENSXMAP00000037122 60.2724 46.0556 ENSG00000065526 homo_sapiens ENSP00000364912 46.0426 33.7609 oryzias_latipes ENSORLP00000032835 55.5482 40.731 ENSG00000065526 homo_sapiens ENSP00000364912 3.43886 3.16594 cyclopterus_lumpus ENSCLMP00005037043 93.3333 85.9259 ENSG00000065526 homo_sapiens ENSP00000364912 48.7991 36.0535 oreochromis_niloticus ENSONIP00000039054 57.9955 42.8479 ENSG00000065526 homo_sapiens ENSP00000364912 3.22052 3.02948 oreochromis_niloticus ENSONIP00000047329 95.1613 89.5161 ENSG00000065526 homo_sapiens ENSP00000364912 58.4334 44.9509 haplochromis_burtoni ENSHBUP00000018529 60.0561 46.1992 ENSG00000065526 homo_sapiens ENSP00000364912 58.4334 44.869 astatotilapia_calliptera ENSACLP00000024915 60.5315 46.4801 ENSG00000065526 homo_sapiens ENSP00000364912 59.3068 45.6059 sparus_aurata ENSSAUP00010012234 61.1252 47.0042 ENSG00000065526 homo_sapiens ENSP00000364912 34.7162 25.3821 lates_calcarifer ENSLCAP00010030962 57.0659 41.7227 ENSG00000065526 homo_sapiens ENSP00000364912 59.143 45.6332 lates_calcarifer ENSLCAP00010001174 61.1974 47.2183 ENSG00000065526 homo_sapiens ENSP00000364912 71.2336 59.3341 xenopus_tropicalis ENSXETP00000113662 74.828 62.328 ENSG00000065526 homo_sapiens ENSP00000364912 78.4116 69.5961 chrysemys_picta_bellii ENSCPBP00000014081 81.0666 71.9526 ENSG00000065526 homo_sapiens ENSP00000364912 66.7303 58.024 sphenodon_punctatus ENSSPUP00000002401 78.4408 68.2066 ENSG00000065526 homo_sapiens ENSP00000364912 3.24782 3.24782 sphenodon_punctatus ENSSPUP00000002384 97.541 97.541 ENSG00000065526 homo_sapiens ENSP00000364912 77.5109 68.9956 crocodylus_porosus ENSCPRP00005024673 75.7737 67.4493 ENSG00000065526 homo_sapiens ENSP00000364912 74.3177 64.1103 laticauda_laticaudata ENSLLTP00000024362 77.4019 66.7709 ENSG00000065526 homo_sapiens ENSP00000364912 74.4814 64.3559 notechis_scutatus ENSNSUP00000026281 77.0904 66.6102 ENSG00000065526 homo_sapiens ENSP00000364912 3.60262 3.60262 pseudonaja_textilis ENSPTXP00000026702 47.1429 47.1429 ENSG00000065526 homo_sapiens ENSP00000364912 63.7555 53.821 pseudonaja_textilis ENSPTXP00000026705 75.0161 63.3269 ENSG00000065526 homo_sapiens ENSP00000364912 77.3745 68.7773 anas_platyrhynchos_platyrhynchos ENSAPLP00000012411 79.3895 70.5685 ENSG00000065526 homo_sapiens ENSP00000364912 71.5066 63.3461 gallus_gallus ENSGALP00010023097 79.6595 70.5686 ENSG00000065526 homo_sapiens ENSP00000364912 62.3908 53.9301 meleagris_gallopavo ENSMGAP00000023125 74.1967 64.135 ENSG00000065526 homo_sapiens ENSP00000364912 77.0197 68.0677 serinus_canaria ENSSCAP00000006282 79.7175 70.452 ENSG00000065526 homo_sapiens ENSP00000364912 65.5841 56.3046 parus_major ENSPMJP00000012186 71.3904 61.2894 ENSG00000065526 homo_sapiens ENSP00000364912 3.65721 3.65721 parus_major ENSPMJP00000012184 99.2593 99.2593 ENSG00000065526 homo_sapiens ENSP00000364912 68.8865 59.607 anolis_carolinensis ENSACAP00000013541 75.6595 65.4676 ENSG00000065526 homo_sapiens ENSP00000364912 46.3155 33.7882 neolamprologus_brichardi ENSNBRP00000028979 56.6422 41.3218 ENSG00000065526 homo_sapiens ENSP00000364912 3.46616 3.22052 neolamprologus_brichardi ENSNBRP00000028994 94.0741 87.4074 ENSG00000065526 homo_sapiens ENSP00000364912 66.7303 56.8231 naja_naja ENSNNAP00000028567 75 63.865 ENSG00000065526 homo_sapiens ENSP00000364912 75.7369 66.4574 podarcis_muralis ENSPMRP00000018137 78.9923 69.314 ENSG00000065526 homo_sapiens ENSP00000364912 77.702 68.6408 taeniopygia_guttata ENSTGUP00000038207 79.5029 70.2318 ENSG00000065526 homo_sapiens ENSP00000364912 66.7849 54.2031 erpetoichthys_calabaricus ENSECRP00000011122 69.517 56.4205 ENSG00000065526 homo_sapiens ENSP00000364912 58.3788 44.5142 kryptolebias_marmoratus ENSKMAP00000005105 60.3385 46.0085 ENSG00000065526 homo_sapiens ENSP00000364912 74.4814 65.3657 salvator_merianae ENSSMRP00000007183 77.6608 68.1559 ENSG00000065526 homo_sapiens ENSP00000364912 3.43886 3.19323 amphilophus_citrinellus ENSACIP00000004226 93.3333 86.6667 ENSG00000065526 homo_sapiens ENSP00000364912 61.4902 46.9705 dicentrarchus_labrax ENSDLAP00005072449 63.6261 48.6021 ENSG00000065526 homo_sapiens ENSP00000364912 59.3068 45.7151 amphiprion_percula ENSAPEP00000014419 61.263 47.223 ENSG00000065526 homo_sapiens ENSP00000364912 2.81114 2.48362 oryzias_sinensis ENSOSIP00000017190 81.746 72.2222 ENSG00000065526 homo_sapiens ENSP00000364912 76.2009 67.3581 pelodiscus_sinensis ENSPSIP00000008829 79.4989 70.2733 ENSG00000065526 homo_sapiens ENSP00000364912 78.8755 70.1965 chelonoidis_abingdonii ENSCABP00000019732 81.6384 72.6554 ENSG00000065526 homo_sapiens ENSP00000364912 59.5797 45.9607 seriola_dumerili ENSSDUP00000004693 61.6667 47.5706 ENSG00000065526 homo_sapiens ENSP00000364912 56.3046 42.7402 cottoperca_gobio ENSCGOP00000014358 61.2166 46.4688 ENSG00000065526 homo_sapiens ENSP00000364912 72.6255 63.5371 struthio_camelus_australis ENSSCUP00000007501 77.3997 67.7138 ENSG00000065526 homo_sapiens ENSP00000364912 75.9279 67.5764 anser_brachyrhynchus ENSABRP00000011659 79.6222 70.8643 ENSG00000065526 homo_sapiens ENSP00000364912 57.6692 44.3504 gasterosteus_aculeatus ENSGACP00000007070 61.4602 47.2659 ENSG00000065526 homo_sapiens ENSP00000364912 57.6419 44.3231 cynoglossus_semilaevis ENSCSEP00000006072 59.6779 45.8887 ENSG00000065526 homo_sapiens ENSP00000364912 43.6954 30.8406 poecilia_formosa ENSPFOP00000014866 55.3979 39.1003 ENSG00000065526 homo_sapiens ENSP00000364912 13.4007 12.3908 poecilia_formosa ENSPFOP00000023775 89.5985 82.8467 ENSG00000065526 homo_sapiens ENSP00000364912 3.46616 3.22052 myripristis_murdjan ENSMMDP00005052321 94.0741 87.4074 ENSG00000065526 homo_sapiens ENSP00000364912 66.9214 58.1878 strigops_habroptila ENSSHBP00005019144 77.7425 67.5967 ENSG00000065526 homo_sapiens ENSP00000364912 59.2795 45.8242 amphiprion_ocellaris ENSAOCP00000026320 61.2521 47.3491 ENSG00000065526 homo_sapiens ENSP00000364912 78.9847 70.3057 terrapene_carolina_triunguis ENSTMTP00000030780 81.2693 72.3392 ENSG00000065526 homo_sapiens ENSP00000364912 5.59498 4.3941 hucho_hucho ENSHHUP00000034047 66.343 52.1036 ENSG00000065526 homo_sapiens ENSP00000364912 43.7773 32.2871 hucho_hucho ENSHHUP00000034059 54.7627 40.3892 ENSG00000065526 homo_sapiens ENSP00000364912 2.64738 2.59279 hucho_hucho ENSHHUP00000034033 88.9908 87.156 ENSG00000065526 homo_sapiens ENSP00000364912 3.43886 3.22052 hucho_hucho ENSHHUP00000015474 93.3333 87.4074 ENSG00000065526 homo_sapiens ENSP00000364912 46.8886 34.0884 hucho_hucho ENSHHUP00000015487 58.8759 42.8033 ENSG00000065526 homo_sapiens ENSP00000364912 3.65721 3.32969 hucho_hucho ENSHHUP00000015478 85.3503 77.707 ENSG00000065526 homo_sapiens ENSP00000364912 3.35699 3.13865 hucho_hucho ENSHHUP00000034038 91.1111 85.1852 ENSG00000065526 homo_sapiens ENSP00000364912 58.5972 45.0873 betta_splendens ENSBSLP00000051411 60.9943 46.9318 ENSG00000065526 homo_sapiens ENSP00000364912 58.4607 46.2336 pygocentrus_nattereri ENSPNAP00000032705 61.2175 48.4138 ENSG00000065526 homo_sapiens ENSP00000364912 59.0884 45.4967 anabas_testudineus ENSATEP00000008007 61.2794 47.1837 ENSG00000065526 homo_sapiens ENSP00000364912 59.5797 45.8242 seriola_lalandi_dorsalis ENSSLDP00000016344 61.5623 47.3491 ENSG00000065526 homo_sapiens ENSP00000364912 45.5786 32.7784 labrus_bergylta ENSLBEP00000025035 55.9839 40.2615 ENSG00000065526 homo_sapiens ENSP00000364912 6.22271 5.5131 labrus_bergylta ENSLBEP00000025084 86.0377 76.2264 ENSG00000065526 homo_sapiens ENSP00000364912 58.4061 44.869 pundamilia_nyererei ENSPNYP00000016376 60.5204 46.4932 ENSG00000065526 homo_sapiens ENSP00000364912 3.43886 3.22052 mastacembelus_armatus ENSMAMP00000021638 93.3333 87.4074 ENSG00000065526 homo_sapiens ENSP00000364912 59.1703 45.6332 stegastes_partitus ENSSPAP00000007870 61.0876 47.1119 ENSG00000065526 homo_sapiens ENSP00000364912 60.8624 46.8614 oncorhynchus_tshawytscha ENSOTSP00005031461 63.03 48.5302 ENSG00000065526 homo_sapiens ENSP00000364912 57.2598 44.7052 oncorhynchus_tshawytscha ENSOTSP00005065158 59.2154 46.232 ENSG00000065526 homo_sapiens ENSP00000364912 57.2598 44.7052 oncorhynchus_tshawytscha ENSOTSP00005016255 59.2154 46.232 ENSG00000065526 homo_sapiens ENSP00000364912 59.3341 45.8515 acanthochromis_polyacanthus ENSAPOP00000007817 61.2912 47.364 ENSG00000065526 homo_sapiens ENSP00000364912 77.3745 68.75 aquila_chrysaetos_chrysaetos ENSACCP00020005368 81.0695 72.0332 ENSG00000065526 homo_sapiens ENSP00000364912 56.5229 43.3406 nothobranchius_furzeri ENSNFUP00015017127 58.8352 45.1136 ENSG00000065526 homo_sapiens ENSP00000364912 57.5873 44.1594 cyprinodon_variegatus ENSCVAP00000013791 59.7903 45.8487 ENSG00000065526 homo_sapiens ENSP00000364912 57.4509 45.4694 denticeps_clupeoides ENSDCDP00000014907 59.8521 47.3699 ENSG00000065526 homo_sapiens ENSP00000364912 59.1976 45.4694 larimichthys_crocea ENSLCRP00005057603 61.0814 46.9164 ENSG00000065526 homo_sapiens ENSP00000364912 57.4509 44.0229 takifugu_rubripes ENSTRUP00000054464 59.8351 45.8499 ENSG00000065526 homo_sapiens ENSP00000364912 3.65721 3.65721 ficedula_albicollis ENSFALP00000021212 99.2593 99.2593 ENSG00000065526 homo_sapiens ENSP00000364912 67.0852 58.1059 ficedula_albicollis ENSFALP00000003703 78.0317 67.5873 ENSG00000065526 homo_sapiens ENSP00000364912 6.00437 5.45852 hippocampus_comes ENSHCOP00000001757 80.8824 73.5294 ENSG00000065526 homo_sapiens ENSP00000364912 3.95742 3.62991 hippocampus_comes ENSHCOP00000018330 91.195 83.6478 ENSG00000065526 homo_sapiens ENSP00000364912 57.0688 44.8963 cyprinus_carpio_carpio ENSCCRP00000134337 60.19 47.3518 ENSG00000065526 homo_sapiens ENSP00000364912 56.25 44.4869 cyprinus_carpio_carpio ENSCCRP00000149018 58.4681 46.2411 ENSG00000065526 homo_sapiens ENSP00000364912 4.99454 4.25764 poecilia_latipinna ENSPLAP00000019348 75.9336 64.7303 ENSG00000065526 homo_sapiens ENSP00000364912 6.68668 5.97707 poecilia_latipinna ENSPLAP00000019353 73.7952 65.9639 ENSG00000065526 homo_sapiens ENSP00000364912 57.3963 45.4148 sinocyclocheilus_grahami ENSSGRP00000000796 60.6751 48.0092 ENSG00000065526 homo_sapiens ENSP00000364912 56.6048 44.9782 sinocyclocheilus_grahami ENSSGRP00000024899 59.1389 46.9917 ENSG00000065526 homo_sapiens ENSP00000364912 50.655 37.7729 maylandia_zebra ENSMZEP00005028805 58.512 43.6318 ENSG00000065526 homo_sapiens ENSP00000364912 3.46616 3.22052 maylandia_zebra ENSMZEP00005028801 94.0741 87.4074 ENSG00000065526 homo_sapiens ENSP00000364912 56.7413 43.9138 tetraodon_nigroviridis ENSTNIP00000013837 63.0382 48.7871 ENSG00000065526 homo_sapiens ENSP00000364912 58.3515 47.1889 paramormyrops_kingsleyae ENSPKIP00000016200 61.1906 49.4848 ENSG00000065526 homo_sapiens ENSP00000364912 60.3166 48.6354 paramormyrops_kingsleyae ENSPKIP00000029223 61.9221 49.93 ENSG00000065526 homo_sapiens ENSP00000364912 59.4432 47.8439 scleropages_formosus ENSSFOP00015015923 61.8574 49.787 ENSG00000065526 homo_sapiens ENSP00000364912 37.309 28.5753 scleropages_formosus ENSSFOP00015011017 54.8555 42.0144 ENSG00000065526 homo_sapiens ENSP00000364912 7.64192 7.31441 leptobrachium_leishanense ENSLLEP00000038248 95.5631 91.4676 ENSG00000065526 homo_sapiens ENSP00000364912 58.9247 45.4421 scophthalmus_maximus ENSSMAP00000014691 60.8855 46.9543 ENSG00000065526 homo_sapiens ENSP00000364912 55.1583 42.0033 oryzias_melastigma ENSOMEP00000006591 58.1248 44.2623
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000122 involved_in negative regulation of transcription by RNA polymerase II 1 IDA Homo_sapiens(9606) Process GO:0003677 enables DNA binding 1 IEA Homo_sapiens(9606) Function GO:0003714 enables transcription corepressor activity 1 IDA Homo_sapiens(9606) Function GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0003729 enables mRNA binding 1 IBA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 1 IBA Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 1 IDA Homo_sapiens(9606) Component GO:0006357 involved_in regulation of transcription by RNA polymerase II 1 IBA Homo_sapiens(9606) Process GO:0007219 involved_in Notch signaling pathway 1 IEA Homo_sapiens(9606) Process GO:0017053 part_of transcription repressor complex 1 IDA Homo_sapiens(9606) Component GO:0045892 involved_in negative regulation of DNA-templated transcription 1 IDA Homo_sapiens(9606) Process GO:0050769 involved_in positive regulation of neurogenesis 1 IMP Homo_sapiens(9606) Process GO:0061629 enables RNA polymerase II-specific DNA-binding transcription factor binding 1 IPI Homo_sapiens(9606) Function GO:0070062 located_in extracellular exosome 1 HDA Homo_sapiens(9606) Component
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