Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucle
BulkPerturb-seq DataSet_02_52

Description

Ensembl ID ENSG00000048740 Gene ID 10659 Accession 2550
Symbol CELF2 Alias ETR3;DEE97;ETR-3;NAPOR;CELF-2;CUGBP2;BRUNOL3;CUG-BP2 Full Name CUGBP Elav-like family member 2
Status Confidence Length 538279 bases Strand Plus strand
Position 10 : 10798397 - 11336675 RNA binding domain RRM_1
Summary Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000476999 RRM_1 PF00076 2e-50 1
ENSP00000476999 RRM_1 PF00076 2e-50 2
ENSP00000476999 RRM_1 PF00076 2e-50 3
ENSP00000382743 RRM_1 PF00076 2e-50 1
ENSP00000382743 RRM_1 PF00076 2e-50 2
ENSP00000382743 RRM_1 PF00076 2e-50 3
ENSP00000404834 RRM_1 PF00076 2e-50 1
ENSP00000404834 RRM_1 PF00076 2e-50 2
ENSP00000404834 RRM_1 PF00076 2e-50 3
ENSP00000487802 RRM_1 PF00076 2e-50 1
ENSP00000487802 RRM_1 PF00076 2e-50 2
ENSP00000487802 RRM_1 PF00076 2e-50 3
ENSP00000490401 RRM_1 PF00076 2e-50 1
ENSP00000490401 RRM_1 PF00076 2e-50 2
ENSP00000490401 RRM_1 PF00076 2e-50 3
ENSP00000346971 RRM_1 PF00076 2.2e-50 1
ENSP00000346971 RRM_1 PF00076 2.2e-50 2
ENSP00000346971 RRM_1 PF00076 2.2e-50 3
ENSP00000406451 RRM_1 PF00076 2.3e-50 1
ENSP00000406451 RRM_1 PF00076 2.3e-50 2
ENSP00000406451 RRM_1 PF00076 2.3e-50 3
ENSP00000488582 RRM_1 PF00076 2.3e-50 1
ENSP00000488582 RRM_1 PF00076 2.3e-50 2
ENSP00000488582 RRM_1 PF00076 2.3e-50 3
ENSP00000488268 RRM_1 PF00076 2.4e-50 1
ENSP00000488268 RRM_1 PF00076 2.4e-50 2
ENSP00000488268 RRM_1 PF00076 2.4e-50 3
ENSP00000489955 RRM_1 PF00076 2.4e-50 1
ENSP00000489955 RRM_1 PF00076 2.4e-50 2
ENSP00000489955 RRM_1 PF00076 2.4e-50 3
ENSP00000490185 RRM_1 PF00076 2.6e-50 1
ENSP00000490185 RRM_1 PF00076 2.6e-50 2
ENSP00000490185 RRM_1 PF00076 2.6e-50 3
ENSP00000443926 RRM_1 PF00076 2.6e-50 1
ENSP00000443926 RRM_1 PF00076 2.6e-50 2
ENSP00000443926 RRM_1 PF00076 2.6e-50 3
ENSP00000488690 RRM_1 PF00076 2.6e-50 1
ENSP00000488690 RRM_1 PF00076 2.6e-50 2
ENSP00000488690 RRM_1 PF00076 2.6e-50 3
ENSP00000488422 RRM_1 PF00076 2.8e-50 1
ENSP00000488422 RRM_1 PF00076 2.8e-50 2
ENSP00000488422 RRM_1 PF00076 2.8e-50 3
ENSP00000476656 RRM_1 PF00076 3.4e-38 1
ENSP00000476656 RRM_1 PF00076 3.4e-38 2
ENSP00000476656 RRM_1 PF00076 3.4e-38 3
ENSP00000476392 RRM_1 PF00076 3.3e-06 1
ENSP00000488438 RRM_1 PF00076 5.6e-06 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
31020708 Pleotropic role of RNA binding protein CELF2 in autophagy induction. Jacob New 2019-08-01 Molecular carcinogenesis
35941702 N6-methyladenosine-mediated CELF2 regulates CD44 alternative splicing affecting tumorigenesis via ERAD pathway in pancreatic cancer. Shihui Lai 2022-08-08 Cell & bioscience
34683087 Systematic Search for Novel Circulating Biomarkers Associated with Extracellular Vesicles in Alzheimer's Disease: Combining Literature Screening and Database Mining Approaches. David Vogrinc 2021-09-23 Journal of personalized medicine
32338744 Reciprocal regulation of hnRNP C and CELF2 through translation and transcription tunes splicing activity in T cells. J Michael Mallory 2020-06-04 Nucleic acids research
23795348 Reduced Expression of RNA Binding Protein CELF2, a Putative Tumor Suppressor Gene in Colon Cancer. Satish Ramalingam 2012-01-01 Immuno-gastroenterology
34636136 miR-363-3p induces EMT via the Wnt/β-catenin pathway in glioma cells by targeting CELF2. Bo Fan 2021-11-01 Journal of cellular and molecular medicine
37131654 Single-cell DNA Methylome and 3D Multi-omic Atlas of the Adult Mouse Brain. Hanqing Liu 2023-04-18 bioRxiv : the preprint server for biology
24413462 An optogenetic gene expression system with rapid activation and deactivation kinetics. B Laura Motta-Mena 2014-03-01 Nature chemical biology
35767654 MECP2-related pathways are dysregulated in a cortical organoid model of myotonic dystrophy. H Kathryn Morelli 2022-06-29 Science translational medicine
28512194 Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes. R Matthew Gazzara 2017-08-01 Genome research
31509743 RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery. Rakesh Chatrikhi 2019-09-10 Cell reports
31409895 Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer. Laia Piqué 2019-11-01 Oncogene
32826865 LncRNA CRNDE facilitates epigenetic suppression of CELF2 and LATS2 to promote proliferation, migration and chemoresistance in hepatocellular carcinoma. Shu-Cai Xie 2020-08-11 Cell death & disease
30425495 microRNA-451 protects neurons against ischemia/reperfusion injury-induced cell death by targeting CELF2. Qian Liu 2018-01-01 Neuropsychiatric disease and treatment
33649373 Alternative splicing events implicated in carcinogenesis and prognosis of thyroid gland cancer. Zeng-Hong Wu 2021-03-01 Scientific reports
31922356 Alternative splicing programming of axon formation. Sika Zheng 2020-07-01 Wiley interdisciplinary reviews. RNA
34107259 Nucleocytoplasmic transport of the RNA-binding protein CELF2 regulates neural stem cell fates. J Melissa MacPherson 2021-06-08 Cell reports
34785939 Prognostic Significance of Alternative Splicing Genes in Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma. Xiaoyu Wang 2021-01-01 International journal of general medicine
37594127 Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review). Jiahao Li 2023-10-01 International journal of molecular medicine
33842332 Genome-Wide Analyses of Prognostic and Therapeutic Alternative Splicing Signatures in Bladder Urothelial Carcinoma. Zhongru Fan 2021-01-01 Frontiers in oncology
26796035 The lack of the Celf2a splicing factor converts a Duchenne genotype into a Becker phenotype. J Martone 2016-01-22 Nature communications
31241130 CELF2 suppresses non-small cell lung carcinoma growth by inhibiting the PREX2-PTEN interaction. To Yiu Yeung 2020-05-14 Carcinogenesis
29965997 Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer. M Knut Wittkowski 2018-01-01 PloS one
31293497 Linkage Evidence for a Two-Locus Inheritance of LQT-Associated Seizures in a Multigenerational LQT Family With a Novel KCNQ1 Loss-of-Function Mutation. Harald Prüss 2019-01-01 Frontiers in neurology
36933216 Alternative splicing of HDAC7 regulates its interaction with 14-3-3 proteins to alter histone marks and target gene expression. M Laura Agosto 2023-03-28 Cell reports

Transcripts

Name Transcript ID bp Protein Translation ID
CELF2-216 ENST00000637215 2724 526aa ENSP00000490185
CELF2-217 ENST00000638035 1849 490aa ENSP00000490401
CELF2-215 ENST00000636488 3908 520aa ENSP00000489955
CELF2-203 ENST00000416382 6894 508aa ENSP00000406451
CELF2-209 ENST00000631460 5538 508aa ENSP00000488582
CELF2-214 ENST00000633200 1496 94aa ENSP00000488438
CELF2-210 ENST00000631816 1803 514aa ENSP00000488268
CELF2-213 ENST00000633077 9406 521aa ENSP00000488690
CELF2-205 ENST00000542579 7982 521aa ENSP00000443926
CELF2-211 ENST00000632065 1952 533aa ENSP00000488422
CELF2-212 ENST00000632728 3827 490aa ENSP00000487802
CELF2-202 ENST00000399850 7085 490aa ENSP00000382743
CELF2-204 ENST00000417956 8044 490aa ENSP00000404834
CELF2-206 ENST00000608830 1892 488aa ENSP00000476999
CELF2-208 ENST00000609870 1549 70aa ENSP00000476392
CELF2-207 ENST00000609692 2210 440aa ENSP00000476656
CELF2-201 ENST00000354897 1754 502aa ENSP00000346971

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
7698Glomerular Filtration Rate4.56204927790083E-517903292
7700Glomerular Filtration Rate5.29972326536875E-517903292
7714Glomerular Filtration Rate3.51876109510041E-517903292
7715Glomerular Filtration Rate6.74801256644168E-517903292
7725Creatinine9.46157803450585E-517903292
7740Creatinine7.49497633821469E-517903292
8033Cystatins5.60146183385957E-517903292
13633E-Selectin6.8604000E-00519729612
15216Heart Failure2.7041388E-004-
15926Stroke6.7929706E-00419369658
16124Stroke7.6012746E-00419369658
25933Arteries4.7530000E-005-
34546Platelet Function Tests5.0685200E-005-
39198Platelet Function Tests3.3900000E-006-
39201Platelet Function Tests9.2200000E-007-
41878Platelet Function Tests3.9327185E-006-
46379Platelet Function Tests2.3870100E-005-
56049Vitamin B 121.3930000E-005-
76928Alzheimer Disease2E-721379329
78454Urine2E-626631737
79781Motion Sickness1E-1025628336
79975Breast Feeding9E-625475840
82288Aspartate Aminotransferases4E-724124411
82903Alanine Transaminase9E-624124411
106294Thyrotropin4E-623251661

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000048740homo_sapiensENSP0000050852586.381377.821homo_sapiensENSP0000048869085.220776.7754
ENSG00000048740homo_sapiensENSP0000022307325.559915.942homo_sapiensENSP0000048869037.236123.2246
ENSG00000048740homo_sapiensENSP0000041058461.522647.5309homo_sapiensENSP0000048869057.389644.3378
ENSG00000048740homo_sapiensENSP0000029267258.969145.3608homo_sapiensENSP0000048869054.894442.2265
ENSG00000048740homo_sapiensENSP0000028720260.083246.1538homo_sapiensENSP0000048869055.470242.6104
ENSG00000048740homo_sapiensENSP0000029058366.236649.8925homo_sapiensENSP0000048869059.117144.5298

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000048740homo_sapiensENSP0000048869096.353295.7774nomascus_leucogenysENSNLEP0000003630595.437394.8669
ENSG00000048740homo_sapiensENSP0000048869096.353295.7774pan_paniscusENSPPAP0000001197695.437394.8669
ENSG00000048740homo_sapiensENSP0000048869096.353295.7774pongo_abeliiENSPPYP0000003330495.437394.8669
ENSG00000048740homo_sapiensENSP0000048869098.848498.4645pan_troglodytesENSPTRP0000008611396.622996.2477
ENSG00000048740homo_sapiensENSP0000048869096.353295.5854gorilla_gorillaENSGGOP0000003652895.437394.6768
ENSG00000048740homo_sapiensENSP0000048869095.009694.0499ornithorhynchus_anatinusENSOANP0000004091586.842185.9649
ENSG00000048740homo_sapiensENSP0000048869096.73796.1612sarcophilus_harrisiiENSSHAP0000002616889.045988.5159
ENSG00000048740homo_sapiensENSP0000048869084.26183.8772notamacropus_eugeniiENSMEUP0000001394890.890390.4762
ENSG00000048740homo_sapiensENSP0000048869075.815775.048choloepus_hoffmanniENSCHOP0000000260982.291781.4583
ENSG00000048740homo_sapiensENSP0000048869097.696797.1209dasypus_novemcinctusENSDNOP0000000018898.073297.4952
ENSG00000048740homo_sapiensENSP0000048869084.836984.6449erinaceus_europaeusENSEEUP0000000515888.75588.5542
ENSG00000048740homo_sapiensENSP0000048869072.360872.1689echinops_telfairiENSETEP0000000684174.212674.0157
ENSG00000048740homo_sapiensENSP0000048869095.969395.5854callithrix_jacchusENSCJAP0000003841995.238194.8571
ENSG00000048740homo_sapiensENSP0000048869098.656498.4645cercocebus_atysENSCATP0000001856096.435396.2477
ENSG00000048740homo_sapiensENSP0000048869098.656498.4645macaca_fascicularisENSMFAP0000002041196.435396.2477
ENSG00000048740homo_sapiensENSP0000048869098.656498.4645macaca_mulattaENSMMUP0000004590096.435396.2477
ENSG00000048740homo_sapiensENSP0000048869091.170890.7869macaca_nemestrinaENSMNEP0000004596294.621594.2231
ENSG00000048740homo_sapiensENSP0000048869098.656498.4645papio_anubisENSPANP0000002923296.435396.2477
ENSG00000048740homo_sapiensENSP0000048869084.069183.3013mandrillus_leucophaeusENSMLEP0000003256295.424894.5534
ENSG00000048740homo_sapiensENSP0000048869087.52486.1804tursiops_truncatusENSTTRP0000001391190.656189.2644
ENSG00000048740homo_sapiensENSP0000048869095.777495.0096vulpes_vulpesENSVVUP0000000856597.081796.3035
ENSG00000048740homo_sapiensENSP0000048869095.009694.0499mus_spretusMGP_SPRETEiJ_P005149794.106593.1559
ENSG00000048740homo_sapiensENSP0000048869095.393594.4338equus_asinusENSEASP0000504947891.697490.7749
ENSG00000048740homo_sapiensENSP0000048869010099.8081capra_hircusENSCHIP0000001432410099.8081
ENSG00000048740homo_sapiensENSP0000048869095.009694.0499loxodonta_africanaENSLAFP0000001139394.106593.1559
ENSG00000048740homo_sapiensENSP0000048869098.656498.0806panthera_leoENSPLOP0000001579796.981196.4151
ENSG00000048740homo_sapiensENSP0000048869095.201594.6257ailuropoda_melanoleucaENSAMEP0000002786491.682191.1275
ENSG00000048740homo_sapiensENSP0000048869095.201594.4338bos_indicus_hybridENSBIXP0000500846791.682190.9427
ENSG00000048740homo_sapiensENSP0000048869096.353295.5854oryctolagus_cuniculusENSOCUP0000000429594.360993.609
ENSG00000048740homo_sapiensENSP0000048869095.393594.4338equus_caballusENSECAP0000000531691.697490.7749
ENSG00000048740homo_sapiensENSP0000048869096.161295.3935canis_lupus_familiarisENSCAFP0084500121195.247194.4867
ENSG00000048740homo_sapiensENSP0000048869098.656498.0806panthera_pardusENSPPRP0000002813096.981196.4151
ENSG00000048740homo_sapiensENSP0000048869095.009694.2418marmota_marmota_marmotaENSMMMP0000001864594.106593.346
ENSG00000048740homo_sapiensENSP0000048869096.353295.7774balaenoptera_musculusENSBMSP0001000738695.437394.8669
ENSG00000048740homo_sapiensENSP0000048869095.009694.2418cavia_porcellusENSCPOP0000001130794.106593.346
ENSG00000048740homo_sapiensENSP0000048869095.201594.2418felis_catusENSFCAP0000002713791.682190.7579
ENSG00000048740homo_sapiensENSP0000048869057.389657.1977ursus_americanusENSUAMP0000001081310099.6656
ENSG00000048740homo_sapiensENSP0000048869079.654578.119monodelphis_domesticaENSMODP0000005509693.679591.8736
ENSG00000048740homo_sapiensENSP0000048869094.049993.666bison_bison_bisonENSBBBP0000002327792.452892.0755
ENSG00000048740homo_sapiensENSP0000048869099.232299.0403monodon_monocerosENSMMNP0001502282997.180596.9925
ENSG00000048740homo_sapiensENSP0000048869096.353295.2015sus_scrofaENSSSCP0000003388891.605890.5109
ENSG00000048740homo_sapiensENSP0000048869095.393594.8177microcebus_murinusENSMICP0000001955894.307493.7381
ENSG00000048740homo_sapiensENSP0000048869095.009694.2418octodon_degusENSODEP0000000111994.106593.346
ENSG00000048740homo_sapiensENSP0000048869094.625793.858jaculus_jaculusENSJJAP0000000707593.904893.1429
ENSG00000048740homo_sapiensENSP0000048869095.201594.4338ovis_aries_rambouilletENSOARP0002000682291.682190.9427
ENSG00000048740homo_sapiensENSP0000048869088.675686.1804ursus_maritimusENSUMAP0000001758890.41187.8669
ENSG00000048740homo_sapiensENSP0000048869094.049993.858ochotona_princepsENSOPRP0000001049396.646996.4497
ENSG00000048740homo_sapiensENSP0000048869010099.8081delphinapterus_leucasENSDLEP0000000577110099.8081
ENSG00000048740homo_sapiensENSP0000048869087.715987.1401physeter_catodonENSPCTP0000500548882.49181.9495
ENSG00000048740homo_sapiensENSP0000048869095.009694.0499mus_caroliMGP_CAROLIEiJ_P004948594.106593.1559
ENSG00000048740homo_sapiensENSP0000048869095.009694.0499mus_musculusENSMUSP0000011057494.106593.1559
ENSG00000048740homo_sapiensENSP0000048869095.009694.2418dipodomys_ordiiENSDORP0000001851794.106593.346
ENSG00000048740homo_sapiensENSP0000048869094.433893.666mustela_putorius_furoENSMPUP0000001630296.850496.063
ENSG00000048740homo_sapiensENSP0000048869096.353295.9693aotus_nancymaaeENSANAP0000001348295.437395.057
ENSG00000048740homo_sapiensENSP0000048869096.353295.9693saimiri_boliviensis_boliviensisENSSBOP0000002491195.437395.057
ENSG00000048740homo_sapiensENSP0000048869074.472274.0883vicugna_pacosENSVPAP0000000870988.787288.3295
ENSG00000048740homo_sapiensENSP0000048869099.808199.8081chlorocebus_sabaeusENSCSAP0000000956699.808199.8081
ENSG00000048740homo_sapiensENSP0000048869093.090292.8983tupaia_belangeriENSTBEP0000000686996.039695.8416
ENSG00000048740homo_sapiensENSP0000048869079.846578.5029mesocricetus_auratusENSMAUP0000000836692.239590.6874
ENSG00000048740homo_sapiensENSP0000048869096.353295.7774phocoena_sinusENSPSNP0000002612595.437394.8669
ENSG00000048740homo_sapiensENSP0000048869094.625793.858camelus_dromedariusENSCDRP0000501763789.963589.2336
ENSG00000048740homo_sapiensENSP0000048869081.573981.5739carlito_syrichtaENSTSYP0000003345086.734786.7347
ENSG00000048740homo_sapiensENSP0000048869080.806176.7754carlito_syrichtaENSTSYP0000003154585.743481.4664
ENSG00000048740homo_sapiensENSP0000048869078.11975.8157panthera_tigris_altaicaENSPTIP0000002284986.411983.8641
ENSG00000048740homo_sapiensENSP0000048869094.625794.0499rattus_norvegicusENSRNOP0000008336891.127590.573
ENSG00000048740homo_sapiensENSP0000048869098.848498.6564prolemur_simusENSPSMP0000002483696.804596.6165
ENSG00000048740homo_sapiensENSP0000048869095.009694.2418microtus_ochrogasterENSMOCP0000000535594.106593.346
ENSG00000048740homo_sapiensENSP0000048869095.009694.2418peromyscus_maniculatus_bairdiiENSPEMP0000001876694.106593.346
ENSG00000048740homo_sapiensENSP0000048869094.049993.666bos_mutusENSBMUP0000003466892.452892.0755
ENSG00000048740homo_sapiensENSP0000048869096.545195.7774mus_spicilegusENSMSIP0000002037591.788391.0584
ENSG00000048740homo_sapiensENSP0000048869094.817794.0499cricetulus_griseus_chok1gshdENSCGRP0000101413393.916493.1559
ENSG00000048740homo_sapiensENSP0000048869058.157457.7735pteropus_vampyrusENSPVAP0000000311059.645759.252
ENSG00000048740homo_sapiensENSP0000048869094.433893.858myotis_lucifugusENSMLUP0000000529696.850496.2598
ENSG00000048740homo_sapiensENSP0000048869099.616198.6564vombatus_ursinusENSVURP0001001881199.616198.6564
ENSG00000048740homo_sapiensENSP0000048869096.545195.5854rhinolophus_ferrumequinumENSRFEP0001002727991.788390.8759
ENSG00000048740homo_sapiensENSP0000048869081.573981.382neovison_visonENSNVIP0000000047386.734786.5306
ENSG00000048740homo_sapiensENSP0000048869098.848498.4645bos_taurusENSBTAP0000001176899.229398.8439
ENSG00000048740homo_sapiensENSP0000048869096.353295.5854heterocephalus_glaber_femaleENSHGLP0000005233394.360993.609
ENSG00000048740homo_sapiensENSP0000048869095.393595.3935rhinopithecus_bietiENSRBIP0000003787292.207892.2078
ENSG00000048740homo_sapiensENSP0000048869098.464598.2726canis_lupus_dingoENSCAFP0002000715399.611699.4175
ENSG00000048740homo_sapiensENSP0000048869096.353295.9693sciurus_vulgarisENSSVLP0000501249895.437395.057
ENSG00000048740homo_sapiensENSP0000048869095.393594.2418phascolarctos_cinereusENSPCIP0000004220892.723991.6045
ENSG00000048740homo_sapiensENSP0000048869090.403189.8273procavia_capensisENSPCAP0000001016090.576990
ENSG00000048740homo_sapiensENSP0000048869089.635388.8676nannospalax_galiliENSNGAP0000002221193.775192.9719
ENSG00000048740homo_sapiensENSP0000048869096.545195.7774bos_grunniensENSBGRP0000002248591.956191.2249
ENSG00000048740homo_sapiensENSP0000048869095.201594.0499chinchilla_lanigeraENSCLAP0000001495094.296693.1559
ENSG00000048740homo_sapiensENSP0000048869095.009694.2418cervus_hanglu_yarkandensisENSCHYP0000003469891.497290.7579
ENSG00000048740homo_sapiensENSP0000048869096.161295.5854catagonus_wagneriENSCWAP0000002763295.247194.6768
ENSG00000048740homo_sapiensENSP0000048869095.009694.2418ictidomys_tridecemlineatusENSSTOP0000000140394.106593.346
ENSG00000048740homo_sapiensENSP0000048869075.815775.8157otolemur_garnettiiENSOGAP0000001839598.503798.5037
ENSG00000048740homo_sapiensENSP0000048869098.848498.6564cebus_imitatorENSCCAP0000000643796.622996.4353
ENSG00000048740homo_sapiensENSP0000048869095.009694.2418urocitellus_parryiiENSUPAP0001000254094.106593.346
ENSG00000048740homo_sapiensENSP0000048869098.848498.4645moschus_moschiferusENSMMSP0000002115196.986896.6102
ENSG00000048740homo_sapiensENSP0000048869092.322590.7869moschus_moschiferusENSMMSP0000002182096.586394.9799
ENSG00000048740homo_sapiensENSP0000048869092.514492.1305rhinopithecus_roxellanaENSRROP0000004283093.957193.5673
ENSG00000048740homo_sapiensENSP0000048869095.009694.0499mus_pahariMGP_PahariEiJ_P004003594.106593.1559
ENSG00000048740homo_sapiensENSP0000048869090.211190.0192propithecus_coquereliENSPCOP0000002735696.509296.3039
ENSG00000048740homo_sapiensENSP0000048869016.50679.21305caenorhabditis_elegansEEED8.4.245.026225.1309
ENSG00000048740homo_sapiensENSP0000048869016.12289.02111caenorhabditis_elegansEEED8.12.142.639623.8579
ENSG00000048740homo_sapiensENSP0000048869015.7399.21305caenorhabditis_elegansT08B6.5.146.327727.1186
ENSG00000048740homo_sapiensENSP0000048869065.64352.0154drosophila_melanogasterFBpp029339638.297930.3471
ENSG00000048740homo_sapiensENSP0000048869064.107550.4798drosophila_melanogasterFBpp030403541.234632.4691
ENSG00000048740homo_sapiensENSP0000048869029.558516.8906drosophila_melanogasterFBpp007223431.111117.7778
ENSG00000048740homo_sapiensENSP0000048869060.652649.5202ciona_intestinalisENSCINP0000000777465.970853.8622
ENSG00000048740homo_sapiensENSP0000048869039.347432.4376petromyzon_marinusENSPMAP0000000283877.651564.0152
ENSG00000048740homo_sapiensENSP000004886908.44538.25336petromyzon_marinusENSPMAP0000000880748.888947.7778
ENSG00000048740homo_sapiensENSP0000048869057.005844.7217petromyzon_marinusENSPMAP0000000734371.912856.4165
ENSG00000048740homo_sapiensENSP0000048869067.754352.0154eptatretus_burgeriENSEBUP0000001281763.833649.0054
ENSG00000048740homo_sapiensENSP0000048869058.733246.6411eptatretus_burgeriENSEBUP0000001229266.521752.8261
ENSG00000048740homo_sapiensENSP0000048869078.11967.1785eptatretus_burgeriENSEBUP0000000338773.333363.0631
ENSG00000048740homo_sapiensENSP0000048869066.794651.8234eptatretus_burgeriENSEBUP0000000320742.542833.0073
ENSG00000048740homo_sapiensENSP0000048869057.389655.6622callorhinchus_miliiENSCMIP0000000599485.673483.0946
ENSG00000048740homo_sapiensENSP0000048869096.92994.4338latimeria_chalumnaeENSLACP0000001111597.115494.6154
ENSG00000048740homo_sapiensENSP0000048869093.66691.3628lepisosteus_oculatusENSLOCP0000001931993.307891.0134
ENSG00000048740homo_sapiensENSP0000048869070.441561.2284clupea_harengusENSCHAP0000004328870.441561.2284
ENSG00000048740homo_sapiensENSP0000048869068.71462.1881esox_luciusENSELUP0000000750190.40481.8182
ENSG00000048740homo_sapiensENSP0000048869083.877273.5125oncorhynchus_kisutchENSOKIP0000510468280.627370.6642
ENSG00000048740homo_sapiensENSP0000048869083.877273.5125oncorhynchus_kisutchENSOKIP0000504052479.454569.6364
ENSG00000048740homo_sapiensENSP0000048869081.765873.1286oncorhynchus_mykissENSOMYP0000009854086.409777.2819
ENSG00000048740homo_sapiensENSP0000048869084.45374.4722oncorhynchus_mykissENSOMYP0000009856281.936772.2533
ENSG00000048740homo_sapiensENSP0000048869084.069173.8964salmo_salarENSSSAP0000009118680.961271.1645
ENSG00000048740homo_sapiensENSP0000048869084.069173.8964salmo_salarENSSSAP0000000813479.491869.873
ENSG00000048740homo_sapiensENSP0000048869083.877273.8964salmo_truttaENSSTUP0000003563979.310369.873
ENSG00000048740homo_sapiensENSP0000048869084.069173.8964salmo_truttaENSSTUP0000008863580.66370.9024
ENSG00000048740homo_sapiensENSP0000048869082.149772.1689gadus_morhuaENSGMOP0000004792585.25974.9004
ENSG00000048740homo_sapiensENSP0000048869075.04865.8349fundulus_heteroclitusENSFHEP0000002511861.574854.0157
ENSG00000048740homo_sapiensENSP0000048869076.775468.5221poecilia_reticulataENSPREP0000001144977.220168.9189
ENSG00000048740homo_sapiensENSP0000048869076.391666.9866xiphophorus_maculatusENSXMAP0000001690966.778558.557
ENSG00000048740homo_sapiensENSP0000048869075.815767.1785oryzias_latipesENSORLP0000002919474.528366.0377
ENSG00000048740homo_sapiensENSP0000048869075.04866.0269cyclopterus_lumpusENSCLMP0000500854774.05365.1515
ENSG00000048740homo_sapiensENSP0000048869072.744763.1478oreochromis_niloticusENSONIP0000006231972.466562.9063
ENSG00000048740homo_sapiensENSP0000048869066.794658.7332haplochromis_burtoniENSHBUP0000002435476.483567.2527
ENSG00000048740homo_sapiensENSP0000048869076.007766.4108astatotilapia_callipteraENSACLP0000000462774.296464.9156
ENSG00000048740homo_sapiensENSP0000048869075.815766.2188sparus_aurataENSSAUP0001002252374.248164.8496
ENSG00000048740homo_sapiensENSP0000048869075.815766.7946lates_calcariferENSLCAP0001004565276.254867.1815
ENSG00000048740homo_sapiensENSP0000048869094.433892.7063xenopus_tropicalisENSXETP0000008562088.969387.3418
ENSG00000048740homo_sapiensENSP0000048869094.817793.4741chrysemys_picta_belliiENSCPBP0000004050692.164290.8582
ENSG00000048740homo_sapiensENSP0000048869087.140186.5643sphenodon_punctatusENSSPUP0000002458698.268497.619
ENSG00000048740homo_sapiensENSP0000048869092.514491.9386crocodylus_porosusENSCPRP0000500134298.770598.1557
ENSG00000048740homo_sapiensENSP0000048869022.072922.0729laticauda_laticaudataENSLLTP0000000795764.971764.9717
ENSG00000048740homo_sapiensENSP0000048869094.817793.666notechis_scutatusENSNSUP0000000441196.862795.6863
ENSG00000048740homo_sapiensENSP0000048869097.312996.1612pseudonaja_textilisENSPTXP0000000000393.370292.2652
ENSG00000048740homo_sapiensENSP0000048869095.009693.4741anas_platyrhynchos_platyrhynchosENSAPLP0000002325893.396291.8868
ENSG00000048740homo_sapiensENSP0000048869095.393594.8177gallus_gallusENSGALP0001000798572.980972.5404
ENSG00000048740homo_sapiensENSP0000048869094.241893.2822meleagris_gallopavoENSMGAP0000002611191.433990.5028
ENSG00000048740homo_sapiensENSP0000048869092.322591.9386serinus_canariaENSSCAP0000001303399.380298.9669
ENSG00000048740homo_sapiensENSP0000048869094.817793.4741parus_majorENSPMJP0000000146193.916492.5855
ENSG00000048740homo_sapiensENSP0000048869098.272696.737anolis_carolinensisENSACAP0000003541087.671286.3014
ENSG00000048740homo_sapiensENSP0000048869076.199666.6027neolamprologus_brichardiENSNBRP0000000032574.484165.1032
ENSG00000048740homo_sapiensENSP0000048869097.312996.1612naja_najaENSNNAP0000000967296.022794.8864
ENSG00000048740homo_sapiensENSP0000048869094.817793.2822podarcis_muralisENSPMRP0000001973181.116679.803
ENSG00000048740homo_sapiensENSP0000048869094.625793.2822geospiza_fortisENSGFOP0000002078893.726292.3954
ENSG00000048740homo_sapiensENSP0000048869098.656497.3129taeniopygia_guttataENSTGUP0000001860390.652689.418
ENSG00000048740homo_sapiensENSP0000048869091.554787.7159erpetoichthys_calabaricusENSECRP0000001495589.661785.9023
ENSG00000048740homo_sapiensENSP0000048869013.435710.5566kryptolebias_marmoratusENSKMAP0000000534761.946948.6726
ENSG00000048740homo_sapiensENSP0000048869021.88118.81kryptolebias_marmoratusENSKMAP0000000533259.067450.7772
ENSG00000048740homo_sapiensENSP0000048869098.080696.5451salvator_merianaeENSSMRP0000000885893.418691.9561
ENSG00000048740homo_sapiensENSP0000048869076.391667.9463oryzias_javanicusENSOJAP0000000103674.81266.5414
ENSG00000048740homo_sapiensENSP0000048869070.825363.3397amphilophus_citrinellusENSACIP0000002505377.684269.4737
ENSG00000048740homo_sapiensENSP0000048869072.744764.6833dicentrarchus_labraxENSDLAP0000505826772.884664.8077
ENSG00000048740homo_sapiensENSP0000048869075.431966.0269amphiprion_perculaENSAPEP0000000462774.011364.7834
ENSG00000048740homo_sapiensENSP0000048869076.199668.714oryzias_sinensisENSOSIP0000002752876.93869.3798
ENSG00000048740homo_sapiensENSP0000048869098.080696.929pelodiscus_sinensisENSPSIP0000001563298.458697.3025
ENSG00000048740homo_sapiensENSP0000048869092.322591.9386gopherus_evgoodeiENSGEVP0000500581799.380298.9669
ENSG00000048740homo_sapiensENSP0000048869094.433893.2822chelonoidis_abingdoniiENSCABP0000000818294.797793.6416
ENSG00000048740homo_sapiensENSP0000048869077.159369.0979seriola_dumeriliENSSDUP0000003131477.90769.7674
ENSG00000048740homo_sapiensENSP0000048869073.704463.7236cottoperca_gobioENSCGOP0000003062472.727362.8788
ENSG00000048740homo_sapiensENSP0000048869086.180484.8369struthio_camelus_australisENSSCUP0000001815990.34288.9336
ENSG00000048740homo_sapiensENSP0000048869094.817793.4741anser_brachyrhynchusENSABRP0000001561193.916492.5855
ENSG00000048740homo_sapiensENSP0000048869075.239964.4914gasterosteus_aculeatusENSGACP0000000584672.727362.3377
ENSG00000048740homo_sapiensENSP0000048869064.491457.7735cynoglossus_semilaevisENSCSEP0000002406473.043565.4348
ENSG00000048740homo_sapiensENSP0000048869076.967468.906poecilia_formosaENSPFOP0000001315977.562969.4391
ENSG00000048740homo_sapiensENSP0000048869086.372478.3109myripristis_murdjanENSMMDP0000504769585.066277.1267
ENSG00000048740homo_sapiensENSP0000048869075.04865.2591sander_luciopercaENSSLUP0000003820373.634764.0301
ENSG00000048740homo_sapiensENSP0000048869094.817793.4741strigops_habroptilaENSSHBP0000500494993.916492.5855
ENSG00000048740homo_sapiensENSP0000048869075.431966.0269amphiprion_ocellarisENSAOCP0000001704374.011364.7834
ENSG00000048740homo_sapiensENSP0000048869099.232298.0806terrapene_carolina_triunguisENSTMTP0000001532699.232298.0806
ENSG00000048740homo_sapiensENSP0000048869084.069173.8964hucho_huchoENSHHUP0000000290980.811871.0332
ENSG00000048740homo_sapiensENSP0000048869084.069173.8964hucho_huchoENSHHUP0000005935878.214368.75
ENSG00000048740homo_sapiensENSP0000048869065.259156.238betta_splendensENSBSLP0000001083267.594458.2505
ENSG00000048740homo_sapiensENSP0000048869076.007766.7946anabas_testudineusENSATEP0000003986574.576365.5367
ENSG00000048740homo_sapiensENSP0000048869061.804250.096ciona_savignyiENSCSAVP0000001303664.452.2
ENSG00000048740homo_sapiensENSP0000048869052.399238.1958ciona_savignyiENSCSAVP0000001283849.726836.2477
ENSG00000048740homo_sapiensENSP0000048869033.589317.0825saccharomyces_cerevisiaeYNL197C26.47513.4644
ENSG00000048740homo_sapiensENSP0000048869032.437616.1228saccharomyces_cerevisiaeYDL224C26.040112.943
ENSG00000048740homo_sapiensENSP0000048869075.815766.7946seriola_lalandi_dorsalisENSSLDP0000001369074.528365.6604
ENSG00000048740homo_sapiensENSP0000048869075.04865.4511labrus_bergyltaENSLBEP0000001376873.773664.3396
ENSG00000048740homo_sapiensENSP0000048869010.17279.59693pundamilia_nyerereiENSPNYP0000003162046.902744.2478
ENSG00000048740homo_sapiensENSP0000048869075.815766.9866mastacembelus_armatusENSMAMP0000003454474.248165.6015
ENSG00000048740homo_sapiensENSP0000048869076.391666.9866stegastes_partitusENSSPAP0000000737275.094365.8491
ENSG00000048740homo_sapiensENSP0000048869070.633461.8042oncorhynchus_tshawytschaENSOTSP0000500505085.780975.0583
ENSG00000048740homo_sapiensENSP0000048869084.26174.4722oncorhynchus_tshawytschaENSOTSP0000509890482.986873.3459
ENSG00000048740homo_sapiensENSP0000048869075.431966.0269acanthochromis_polyacanthusENSAPOP0000002544874.011364.7834
ENSG00000048740homo_sapiensENSP0000048869099.424298.4645aquila_chrysaetos_chrysaetosENSACCP0002000533899.424298.4645
ENSG00000048740homo_sapiensENSP0000048869074.85665.643nothobranchius_furzeriENSNFUP0001504754275.875566.537
ENSG00000048740homo_sapiensENSP0000048869075.431965.8349cyprinodon_variegatusENSCVAP0000000742274.011364.5951
ENSG00000048740homo_sapiensENSP0000048869071.593162.1881denticeps_clupeoidesENSDCDP0000001342974.664.8
ENSG00000048740homo_sapiensENSP0000048869076.199667.1785larimichthys_croceaENSLCRP0000503591374.764665.9134
ENSG00000048740homo_sapiensENSP0000048869075.623866.4108takifugu_rubripesENSTRUP0000004330876.504967.1845
ENSG00000048740homo_sapiensENSP0000048869095.777494.8177ficedula_albicollisENSFALP0000003426093.62192.6829
ENSG00000048740homo_sapiensENSP0000048869094.817793.4741coturnix_japonicaENSCJPP0000500422593.916492.5855
ENSG00000048740homo_sapiensENSP0000048869076.967468.5221poecilia_latipinnaENSPLAP0000001723177.562969.0522
ENSG00000048740homo_sapiensENSP0000048869076.007766.4108maylandia_zebraENSMZEP0000500914974.296464.9156
ENSG00000048740homo_sapiensENSP0000048869074.088365.643tetraodon_nigroviridisENSTNIP0000001909877.979869.0909
ENSG00000048740homo_sapiensENSP0000048869091.746687.9079paramormyrops_kingsleyaeENSPKIP0000001025488.847685.1301
ENSG00000048740homo_sapiensENSP0000048869091.362886.5643scleropages_formosusENSSFOP0001503742190.839786.0687
ENSG00000048740homo_sapiensENSP0000048869092.898388.0998scleropages_formosusENSSFOP0001504089190.806886.1163
ENSG00000048740homo_sapiensENSP0000048869096.73794.4338leptobrachium_leishanenseENSLLEP0000002009993.506591.2802
ENSG00000048740homo_sapiensENSP0000048869072.168963.3397scophthalmus_maximusENSSMAP0000006322075.049965.8683
ENSG00000048740homo_sapiensENSP0000048869076.199667.5624oryzias_melastigmaENSOMEP0000001040674.484166.0413

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000381involved_in regulation of alternative mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003730enables mRNA 3-UTR binding1IBAHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus3IBA,IDA,IMPHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0006376involved_in mRNA splice site recognition2IBA,IDAHomo_sapiens(9606)Process
GO:0006396involved_in RNA processing1TASHomo_sapiens(9606)Process
GO:0008016involved_in regulation of heart contraction1TASHomo_sapiens(9606)Process
GO:0036002enables pre-mRNA binding1IDAHomo_sapiens(9606)Function
GO:0043231located_in intracellular membrane-bounded organelle1IDAHomo_sapiens(9606)Component
GO:0090543located_in Flemming body1IDAHomo_sapiens(9606)Component
GO:1990904part_of ribonucleoprotein complex1IBAHomo_sapiens(9606)Component

Expression