Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2DengueZika
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000014641 Gene ID 4190 Accession 6970
Symbol MDH1 Alias KAR;MDHA;MOR2;DEE88;MDH-s;EIEE88;HEL-S-32;MGC:1375 Full Name malate dehydrogenase 1
Status Confidence Length 18589 bases Strand Plus strand
Position 2 : 63588609 - 63607197 RNA binding domain N.A.
Summary This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
MDH1-213 ENST00000485781 893 No protein -
MDH1-216 ENST00000544381 1647 334aa ENSP00000446395
MDH1-203 ENST00000409908 700 169aa ENSP00000386743
MDH1-207 ENST00000442225 785 67aa ENSP00000399004
MDH1-201 ENST00000233114 1296 334aa ENSP00000233114
MDH1-215 ENST00000539945 1296 353aa ENSP00000438144
MDH1-202 ENST00000409476 808 210aa ENSP00000386719
MDH1-212 ENST00000485155 571 No protein -
MDH1-206 ENST00000436321 680 119aa ENSP00000394504
MDH1-209 ENST00000462944 634 No protein -
MDH1-208 ENST00000454035 575 114aa ENSP00000409027
MDH1-210 ENST00000472098 936 No protein -
MDH1-204 ENST00000421012 1346 87aa ENSP00000400937
MDH1-205 ENST00000432309 1443 352aa ENSP00000410073
MDH1-211 ENST00000484538 910 No protein -
MDH1-214 ENST00000495083 552 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
47284Blood Pressure3.4586055E-009-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000014641homo_sapiensENSP0000036353330.501917.9537homo_sapiensENSP0000023311447.305427.8443

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000014641homo_sapiensENSP0000023311499.700698.8024nomascus_leucogenysENSNLEP0000002538594.602393.75
ENSG00000014641homo_sapiensENSP0000023311498.203697.9042pan_paniscusENSPPAP0000003960599.69699.3921
ENSG00000014641homo_sapiensENSP0000023311410099.1018pongo_abeliiENSPPYP0000001379710099.1018
ENSG00000014641homo_sapiensENSP0000023311499.700699.4012pan_troglodytesENSPTRP0000008817694.602394.3182
ENSG00000014641homo_sapiensENSP0000023311499.700699.1018gorilla_gorillaENSGGOP0000003979794.602394.0341
ENSG00000014641homo_sapiensENSP0000023311497.604891.6168ornithorhynchus_anatinusENSOANP0000001966497.604891.6168
ENSG00000014641homo_sapiensENSP0000023311497.305489.8204sarcophilus_harrisiiENSSHAP0000002644797.305489.8204
ENSG00000014641homo_sapiensENSP0000023311429.341327.2455notamacropus_eugeniiENSMEUP0000001292858.333354.1667
ENSG00000014641homo_sapiensENSP0000023311455.089852.0958notamacropus_eugeniiENSMEUP0000001457655.255352.2523
ENSG00000014641homo_sapiensENSP0000023311498.203692.2156choloepus_hoffmanniENSCHOP0000000645698.203692.2156
ENSG00000014641homo_sapiensENSP0000023311498.802494.012dasypus_novemcinctusENSDNOP0000001033298.802494.012
ENSG00000014641homo_sapiensENSP0000023311496.407293.4132erinaceus_europaeusENSEEUP0000000108096.407293.4132
ENSG00000014641homo_sapiensENSP0000023311483.532979.6407echinops_telfairiENSETEP0000000615383.532979.6407
ENSG00000014641homo_sapiensENSP0000023311474.850370.9581echinops_telfairiENSETEP0000000566696.525191.5058
ENSG00000014641homo_sapiensENSP0000023311480.239578.7425callithrix_jacchusENSCJAP0000004055798.89397.048
ENSG00000014641homo_sapiensENSP0000023311410098.8024callithrix_jacchusENSCJAP0000001309210098.8024
ENSG00000014641homo_sapiensENSP0000023311480.838380.2395cercocebus_atysENSCATP0000001278399.63198.893
ENSG00000014641homo_sapiensENSP0000023311499.700699.1018macaca_fascicularisENSMFAP0000004821994.334393.7677
ENSG00000014641homo_sapiensENSP0000023311499.401298.8024macaca_mulattaENSMMUP0000005438594.05193.4844
ENSG00000014641homo_sapiensENSP0000023311499.700699.1018macaca_nemestrinaENSMNEP0000003154094.602394.0341
ENSG00000014641homo_sapiensENSP0000023311499.700699.1018papio_anubisENSPANP0000003992999.700699.1018
ENSG00000014641homo_sapiensENSP0000023311499.700699.1018mandrillus_leucophaeusENSMLEP0000001064994.602394.0341
ENSG00000014641homo_sapiensENSP0000023311497.904294.6108tursiops_truncatusENSTTRP0000000499098.49495.1807
ENSG00000014641homo_sapiensENSP0000023311498.203695.2096vulpes_vulpesENSVVUP0000001669598.203695.2096
ENSG00000014641homo_sapiensENSP0000023311499.401296.4072mus_spretusMGP_SPRETEiJ_P002716199.401296.4072
ENSG00000014641homo_sapiensENSP0000023311498.50396.4072equus_asinusENSEASP0000504267793.465991.4773
ENSG00000014641homo_sapiensENSP0000023311468.263562.5749capra_hircusENSCHIP0000002623582.310575.4513
ENSG00000014641homo_sapiensENSP0000023311498.802495.509capra_hircusENSCHIP0000001457498.802495.509
ENSG00000014641homo_sapiensENSP0000023311496.407292.515loxodonta_africanaENSLAFP0000001386096.407292.515
ENSG00000014641homo_sapiensENSP0000023311497.604894.3114panthera_leoENSPLOP0000000056997.604894.3114
ENSG00000014641homo_sapiensENSP0000023311498.50395.509ailuropoda_melanoleucaENSAMEP0000000574398.50395.509
ENSG00000014641homo_sapiensENSP0000023311498.802495.509bos_indicus_hybridENSBIXP0000500293998.802495.509
ENSG00000014641homo_sapiensENSP0000023311499.101896.7066oryctolagus_cuniculusENSOCUP0000000534099.101896.7066
ENSG00000014641homo_sapiensENSP0000023311498.50395.8084equus_caballusENSECAP0000006945993.465990.9091
ENSG00000014641homo_sapiensENSP0000023311498.203695.2096canis_lupus_familiarisENSCAFP0084502635692.655489.8305
ENSG00000014641homo_sapiensENSP0000023311497.604894.012panthera_pardusENSPPRP0000000024797.023893.4524
ENSG00000014641homo_sapiensENSP0000023311497.604894.3114panthera_pardusENSPPRP0000002482597.604894.3114
ENSG00000014641homo_sapiensENSP0000023311499.401295.2096marmota_marmota_marmotaENSMMMP0000000704099.401295.2096
ENSG00000014641homo_sapiensENSP0000023311498.50394.3114balaenoptera_musculusENSBMSP0001002253591.643587.7437
ENSG00000014641homo_sapiensENSP0000023311499.101895.8084cavia_porcellusENSCPOP0000000965598.80695.5224
ENSG00000014641homo_sapiensENSP0000023311497.604894.9102felis_catusENSFCAP0000002943397.604894.9102
ENSG00000014641homo_sapiensENSP0000023311491.317486.2275ursus_americanusENSUAMP0000001678795.015689.7196
ENSG00000014641homo_sapiensENSP0000023311497.00691.018monodelphis_domesticaENSMODP0000005296791.011285.3933
ENSG00000014641homo_sapiensENSP0000023311498.802495.509bison_bison_bisonENSBBBP0000000785898.802495.509
ENSG00000014641homo_sapiensENSP0000023311447.305444.012monodon_monocerosENSMMNP0001500041289.265583.0508
ENSG00000014641homo_sapiensENSP0000023311498.50395.2096monodon_monocerosENSMMNP0001501229598.50395.2096
ENSG00000014641homo_sapiensENSP0000023311498.50395.509sus_scrofaENSSSCP0000000893392.937990.113
ENSG00000014641homo_sapiensENSP0000023311443.113837.7246microcebus_murinusENSMICP0000004595680.446970.3911
ENSG00000014641homo_sapiensENSP0000023311498.802496.4072microcebus_murinusENSMICP0000003707093.7591.4773
ENSG00000014641homo_sapiensENSP0000023311497.904294.6108octodon_degusENSODEP0000001569798.198294.8949
ENSG00000014641homo_sapiensENSP0000023311498.50395.2096jaculus_jaculusENSJJAP0000002509098.50395.2096
ENSG00000014641homo_sapiensENSP0000023311498.802495.509ovis_aries_rambouilletENSOARP0002000149898.802495.509
ENSG00000014641homo_sapiensENSP0000023311498.50395.509ursus_maritimusENSUMAP0000002889698.50395.509
ENSG00000014641homo_sapiensENSP0000023311475.748573.6527ochotona_princepsENSOPRP0000001255275.97673.8739
ENSG00000014641homo_sapiensENSP0000023311498.50395.2096delphinapterus_leucasENSDLEP0000001880898.50395.2096
ENSG00000014641homo_sapiensENSP0000023311498.50394.9102physeter_catodonENSPCTP0000501016998.50394.9102
ENSG00000014641homo_sapiensENSP0000023311499.401296.4072mus_caroliMGP_CAROLIEiJ_P002582499.401296.4072
ENSG00000014641homo_sapiensENSP0000023311499.401296.4072mus_musculusENSMUSP0000015904993.521190.7042
ENSG00000014641homo_sapiensENSP0000023311498.50394.9102dipodomys_ordiiENSDORP0000000008798.50394.9102
ENSG00000014641homo_sapiensENSP0000023311498.50395.509mustela_putorius_furoENSMPUP0000000587998.50395.509
ENSG00000014641homo_sapiensENSP0000023311499.700698.8024aotus_nancymaaeENSANAP0000004166194.602393.75
ENSG00000014641homo_sapiensENSP0000023311475.449168.5629aotus_nancymaaeENSANAP0000003534089.045980.9187
ENSG00000014641homo_sapiensENSP0000023311494.910293.7126aotus_nancymaaeENSANAP0000003571597.839596.6049
ENSG00000014641homo_sapiensENSP0000023311493.712691.3174saimiri_boliviensis_boliviensisENSSBOP0000001360096.604994.1358
ENSG00000014641homo_sapiensENSP0000023311499.401298.503saimiri_boliviensis_boliviensisENSSBOP0000003986494.586993.7322
ENSG00000014641homo_sapiensENSP0000023311482.634779.0419saimiri_boliviensis_boliviensisENSSBOP0000001617693.243289.1892
ENSG00000014641homo_sapiensENSP0000023311498.203695.2096vicugna_pacosENSVPAP0000001159598.498595.4955
ENSG00000014641homo_sapiensENSP0000023311410099.1018chlorocebus_sabaeusENSCSAP0000001080910099.1018
ENSG00000014641homo_sapiensENSP0000023311459.580856.8862tupaia_belangeriENSTBEP0000000974861.609958.8235
ENSG00000014641homo_sapiensENSP0000023311498.802494.9102mesocricetus_auratusENSMAUP0000001993998.507594.6269
ENSG00000014641homo_sapiensENSP0000023311498.50394.9102phocoena_sinusENSPSNP0000002094598.50394.9102
ENSG00000014641homo_sapiensENSP0000023311498.203694.9102camelus_dromedariusENSCDRP0000500800393.181890.0568
ENSG00000014641homo_sapiensENSP0000023311497.904294.9102carlito_syrichtaENSTSYP0000000112393.162490.3134
ENSG00000014641homo_sapiensENSP0000023311475.748570.0599carlito_syrichtaENSTSYP0000003024989.399382.6855
ENSG00000014641homo_sapiensENSP0000023311495.50991.9162carlito_syrichtaENSTSYP0000001790198.153894.4615
ENSG00000014641homo_sapiensENSP0000023311497.604894.012panthera_tigris_altaicaENSPTIP0000001658997.023893.4524
ENSG00000014641homo_sapiensENSP0000023311499.700697.006rattus_norvegicusENSRNOP0000008869698.230195.5752
ENSG00000014641homo_sapiensENSP0000023311439.820434.4311prolemur_simusENSPSMP0000003165682.098870.9877
ENSG00000014641homo_sapiensENSP0000023311499.101897.3054prolemur_simusENSPSMP0000000510094.30292.5926
ENSG00000014641homo_sapiensENSP0000023311450.598847.6048prolemur_simusENSPSMP0000001189088.947483.6842
ENSG00000014641homo_sapiensENSP0000023311499.401296.1078microtus_ochrogasterENSMOCP0000001658899.401296.1078
ENSG00000014641homo_sapiensENSP0000023311498.802495.2096sorex_araneusENSSARP0000000695999.099195.4955
ENSG00000014641homo_sapiensENSP0000023311487.724584.1317peromyscus_maniculatus_bairdiiENSPEMP0000000500494.82290.9385
ENSG00000014641homo_sapiensENSP0000023311498.802495.509bos_mutusENSBMUP0000002977098.802495.509
ENSG00000014641homo_sapiensENSP0000023311499.401296.4072mus_spicilegusENSMSIP0000003824399.401296.4072
ENSG00000014641homo_sapiensENSP0000023311499.101895.2096cricetulus_griseus_chok1gshdENSCGRP0000102259799.101895.2096
ENSG00000014641homo_sapiensENSP0000023311497.904295.509pteropus_vampyrusENSPVAP0000000491798.198295.7958
ENSG00000014641homo_sapiensENSP0000023311498.50395.2096myotis_lucifugusENSMLUP0000000213693.465990.3409
ENSG00000014641homo_sapiensENSP0000023311497.305491.6168vombatus_ursinusENSVURP0001001741097.305491.6168
ENSG00000014641homo_sapiensENSP0000023311498.50394.3114rhinolophus_ferrumequinumENSRFEP0001001281698.50394.3114
ENSG00000014641homo_sapiensENSP0000023311497.904294.9102neovison_visonENSNVIP0000001298393.162490.3134
ENSG00000014641homo_sapiensENSP0000023311498.802495.509bos_taurusENSBTAP0000006980898.802495.509
ENSG00000014641homo_sapiensENSP0000023311498.50394.9102heterocephalus_glaber_femaleENSHGLP0000003565098.50394.9102
ENSG00000014641homo_sapiensENSP0000023311497.904297.006rhinopithecus_bietiENSRBIP0000003524894.508793.6416
ENSG00000014641homo_sapiensENSP0000023311498.203695.2096canis_lupus_dingoENSCAFP0002003476598.203695.2096
ENSG00000014641homo_sapiensENSP0000023311499.401296.7066sciurus_vulgarisENSSVLP0000502804899.401296.7066
ENSG00000014641homo_sapiensENSP0000023311497.305491.6168phascolarctos_cinereusENSPCIP0000003310397.305491.6168
ENSG00000014641homo_sapiensENSP0000023311458.98256.8862procavia_capensisENSPCAP0000000335894.258490.9091
ENSG00000014641homo_sapiensENSP0000023311498.50394.6108nannospalax_galiliENSNGAP0000002482298.50394.6108
ENSG00000014641homo_sapiensENSP0000023311498.802495.509bos_grunniensENSBGRP0000001628298.802495.509
ENSG00000014641homo_sapiensENSP0000023311498.203694.9102chinchilla_lanigeraENSCLAP0000001132898.203694.9102
ENSG00000014641homo_sapiensENSP0000023311498.802495.509cervus_hanglu_yarkandensisENSCHYP0000001083098.802495.509
ENSG00000014641homo_sapiensENSP0000023311498.802495.8084catagonus_wagneriENSCWAP0000001933698.802495.8084
ENSG00000014641homo_sapiensENSP0000023311499.401295.2096ictidomys_tridecemlineatusENSSTOP0000003075399.401295.2096
ENSG00000014641homo_sapiensENSP0000023311461.377250.5988otolemur_garnettiiENSOGAP0000001640471.678359.0909
ENSG00000014641homo_sapiensENSP0000023311499.101895.509otolemur_garnettiiENSOGAP0000001298199.101895.509
ENSG00000014641homo_sapiensENSP0000023311478.143775.7485cebus_imitatorENSCCAP0000001184594.223891.3357
ENSG00000014641homo_sapiensENSP0000023311499.700698.8024cebus_imitatorENSCCAP0000003012597.084596.2099
ENSG00000014641homo_sapiensENSP0000023311499.101894.6108urocitellus_parryiiENSUPAP0001001368199.101894.6108
ENSG00000014641homo_sapiensENSP0000023311498.802495.2096moschus_moschiferusENSMMSP0000001028498.802495.2096
ENSG00000014641homo_sapiensENSP0000023311499.700698.8024rhinopithecus_roxellanaENSRROP0000002504994.602393.75
ENSG00000014641homo_sapiensENSP0000023311498.802496.1078mus_pahariMGP_PahariEiJ_P003012998.802496.1078
ENSG00000014641homo_sapiensENSP0000023311498.802496.7066propithecus_coquereliENSPCOP0000002099693.7591.7614
ENSG00000014641homo_sapiensENSP0000023311473.952170.0599propithecus_coquereliENSPCOP0000002669491.821686.9888
ENSG00000014641homo_sapiensENSP0000023311473.952160.1796caenorhabditis_elegansF46E10.10.173.511959.8214
ENSG00000014641homo_sapiensENSP0000023311477.844366.1677drosophila_melanogasterFBpp031156077.151365.5786
ENSG00000014641homo_sapiensENSP0000023311479.341364.3713ciona_intestinalisENSCINP0000003649479.341364.3713
ENSG00000014641homo_sapiensENSP0000023311447.305441.3174petromyzon_marinusENSPMAP0000000701994.610882.6347
ENSG00000014641homo_sapiensENSP0000023311457.784448.503eptatretus_burgeriENSEBUP0000002660881.434668.3544
ENSG00000014641homo_sapiensENSP0000023311486.826375.7485callorhinchus_miliiENSCMIP0000000357886.309575.2976
ENSG00000014641homo_sapiensENSP0000023311493.712684.4311latimeria_chalumnaeENSLACP0000001889393.432884.1791
ENSG00000014641homo_sapiensENSP0000023311491.616881.1377lepisosteus_oculatusENSLOCP0000001979687.428677.4286
ENSG00000014641homo_sapiensENSP0000023311490.119877.2455clupea_harengusENSCHAP0000000188088.529475.8824
ENSG00000014641homo_sapiensENSP0000023311490.119877.8443clupea_harengusENSCHAP0000002882481.132170.0809
ENSG00000014641homo_sapiensENSP0000023311472.455162.2754danio_rerioENSDARP0000013827373.556263.2219
ENSG00000014641homo_sapiensENSP0000023311490.119878.4431danio_rerioENSDARP0000002312190.390478.6787
ENSG00000014641homo_sapiensENSP0000023311490.119878.1437carassius_auratusENSCARP000000038918674.5714
ENSG00000014641homo_sapiensENSP0000023311488.922277.2455carassius_auratusENSCARP0000013298377.748767.5393
ENSG00000014641homo_sapiensENSP0000023311459.880252.0958carassius_auratusENSCARP0000008759380.971770.4453
ENSG00000014641homo_sapiensENSP0000023311490.718678.7425carassius_auratusENSCARP0000006501290.718678.7425
ENSG00000014641homo_sapiensENSP0000023311459.281452.3952carassius_auratusENSCARP0000012084978.260969.17
ENSG00000014641homo_sapiensENSP0000023311490.718678.7425carassius_auratusENSCARP0000001603983.701772.6519
ENSG00000014641homo_sapiensENSP0000023311482.035971.8563astyanax_mexicanusENSAMXP0000000285189.542578.4314
ENSG00000014641homo_sapiensENSP0000023311490.119879.6407astyanax_mexicanusENSAMXP000000539318676
ENSG00000014641homo_sapiensENSP0000023311489.221676.9461astyanax_mexicanusENSAMXP0000002856589.489577.1772
ENSG00000014641homo_sapiensENSP0000023311491.01879.9401ictalurus_punctatusENSIPUP0000000853184.916274.581
ENSG00000014641homo_sapiensENSP0000023311489.52179.9401ictalurus_punctatusENSIPUP0000001943089.789880.1802
ENSG00000014641homo_sapiensENSP0000023311488.323478.7425esox_luciusENSELUP0000003504788.323478.7425
ENSG00000014641homo_sapiensENSP0000023311488.622876.9461esox_luciusENSELUP0000001222784.571473.4286
ENSG00000014641homo_sapiensENSP0000023311487.125776.6467electrophorus_electricusENSEEEP0000001064080.609470.9141
ENSG00000014641homo_sapiensENSP0000023311488.622879.3413electrophorus_electricusENSEEEP0000003622683.852775.0708
ENSG00000014641homo_sapiensENSP0000023311488.622877.2455oncorhynchus_kisutchENSOKIP0000510136780.434870.1087
ENSG00000014641homo_sapiensENSP0000023311487.724577.2455oncorhynchus_kisutchENSOKIP0000510499073.067364.3391
ENSG00000014641homo_sapiensENSP0000023311487.724577.2455oncorhynchus_kisutchENSOKIP0000509936569.761961.4286
ENSG00000014641homo_sapiensENSP0000023311488.622877.5449oncorhynchus_kisutchENSOKIP0000505425984.571474
ENSG00000014641homo_sapiensENSP0000023311488.622877.5449oncorhynchus_mykissENSOMYP0000007909182.681672.3464
ENSG00000014641homo_sapiensENSP0000023311487.724576.9461oncorhynchus_mykissENSOMYP0000013532284.927574.4928
ENSG00000014641homo_sapiensENSP0000023311488.023976.9461oncorhynchus_mykissENSOMYP000000016387061.1905
ENSG00000014641homo_sapiensENSP0000023311488.622877.2455oncorhynchus_mykissENSOMYP0000010789784.571473.7143
ENSG00000014641homo_sapiensENSP0000023311488.622877.5449salmo_salarENSSSAP0000017011784.571474
ENSG00000014641homo_sapiensENSP0000023311481.736571.5569salmo_salarENSSSAP0000001352086.119975.3943
ENSG00000014641homo_sapiensENSP0000023311487.724576.6467salmo_salarENSSSAP0000005295573.067363.8404
ENSG00000014641homo_sapiensENSP0000023311488.622876.9461salmo_salarENSSSAP0000008243084.571473.4286
ENSG00000014641homo_sapiensENSP0000023311488.323477.2455salmo_truttaENSSTUP0000004305585.014474.3516
ENSG00000014641homo_sapiensENSP0000023311488.023977.2455salmo_truttaENSSTUP0000004459484.726274.3516
ENSG00000014641homo_sapiensENSP0000023311488.622877.5449salmo_truttaENSSTUP0000009420484.571474
ENSG00000014641homo_sapiensENSP0000023311488.622876.9461salmo_truttaENSSTUP0000006848884.571473.4286
ENSG00000014641homo_sapiensENSP0000023311489.820478.4431gadus_morhuaENSGMOP0000005679185.714374.8571
ENSG00000014641homo_sapiensENSP0000023311488.922276.0479gadus_morhuaENSGMOP0000005203084.857172.5714
ENSG00000014641homo_sapiensENSP0000023311489.52176.9461fundulus_heteroclitusENSFHEP0000002210785.428673.4286
ENSG00000014641homo_sapiensENSP0000023311488.323477.2455fundulus_heteroclitusENSFHEP0000002756288.323477.2455
ENSG00000014641homo_sapiensENSP0000023311489.221677.2455poecilia_reticulataENSPREP0000003025689.489577.4775
ENSG00000014641homo_sapiensENSP0000023311488.622877.8443poecilia_reticulataENSPREP0000003154288.888978.0781
ENSG00000014641homo_sapiensENSP0000023311488.922278.4431xiphophorus_maculatusENSXMAP0000000559889.189278.6787
ENSG00000014641homo_sapiensENSP0000023311489.221677.2455xiphophorus_maculatusENSXMAP0000002732285.142973.7143
ENSG00000014641homo_sapiensENSP0000023311489.820476.9461oryzias_latipesENSORLP0000004330385.714373.4286
ENSG00000014641homo_sapiensENSP0000023311488.622877.2455oryzias_latipesENSORLP0000003319188.888977.4775
ENSG00000014641homo_sapiensENSP0000023311490.119877.5449cyclopterus_lumpusENSCLMP0000501913290.390477.7778
ENSG00000014641homo_sapiensENSP0000023311489.221677.5449cyclopterus_lumpusENSCLMP0000502735183.240272.3464
ENSG00000014641homo_sapiensENSP0000023311484.431172.7545oreochromis_niloticusENSONIP0000007615877.472566.7582
ENSG00000014641homo_sapiensENSP0000023311489.221678.4431oreochromis_niloticusENSONIP0000004133177.806868.4073
ENSG00000014641homo_sapiensENSP0000023311490.419279.3413haplochromis_burtoniENSHBUP0000000773586.285775.7143
ENSG00000014641homo_sapiensENSP0000023311479.940167.3653haplochromis_burtoniENSHBUP0000001620555.857747.0711
ENSG00000014641homo_sapiensENSP0000023311488.922277.8443astatotilapia_callipteraENSACLP0000003944972.262863.2603
ENSG00000014641homo_sapiensENSP0000023311490.419279.3413astatotilapia_callipteraENSACLP0000002120790.419279.3413
ENSG00000014641homo_sapiensENSP0000023311490.419276.9461sparus_aurataENSSAUP0001000011486.039973.2194
ENSG00000014641homo_sapiensENSP0000023311487.724576.9461sparus_aurataENSSAUP0001000695585.174474.7093
ENSG00000014641homo_sapiensENSP0000023311490.119878.4431lates_calcariferENSLCAP000100594968674.8571
ENSG00000014641homo_sapiensENSP0000023311489.52178.4431lates_calcariferENSLCAP0001002861689.253778.209
ENSG00000014641homo_sapiensENSP0000023311493.712686.8263xenopus_tropicalisENSXETP0000008509193.712686.8263
ENSG00000014641homo_sapiensENSP0000023311497.305490.7186chrysemys_picta_belliiENSCPBP0000001805693.123286.8195
ENSG00000014641homo_sapiensENSP0000023311496.706691.9162sphenodon_punctatusENSSPUP0000001673796.706691.9162
ENSG00000014641homo_sapiensENSP0000023311496.706691.3174crocodylus_porosusENSCPRP0000501869178.019373.6715
ENSG00000014641homo_sapiensENSP0000023311480.239573.9521laticauda_laticaudataENSLLTP0000000660995.714388.2143
ENSG00000014641homo_sapiensENSP0000023311496.407289.521notechis_scutatusENSNSUP0000002665096.119489.2537
ENSG00000014641homo_sapiensENSP0000023311496.407290.4192pseudonaja_textilisENSPTXP0000000906496.119490.1493
ENSG00000014641homo_sapiensENSP0000023311496.706690.4192anas_platyrhynchos_platyrhynchosENSAPLP0000000973096.706690.4192
ENSG00000014641homo_sapiensENSP0000023311496.706690.4192gallus_gallusENSGALP0001002324296.417990.1493
ENSG00000014641homo_sapiensENSP0000023311489.221682.9341meleagris_gallopavoENSMGAP0000000477494.603287.9365
ENSG00000014641homo_sapiensENSP0000023311496.107890.4192serinus_canariaENSSCAP0000000094896.107890.4192
ENSG00000014641homo_sapiensENSP0000023311496.706690.4192parus_majorENSPMJP0000000280496.706690.4192
ENSG00000014641homo_sapiensENSP0000023311496.107888.6228anolis_carolinensisENSACAP0000000579596.107888.6228
ENSG00000014641homo_sapiensENSP0000023311490.419279.0419neolamprologus_brichardiENSNBRP0000001112586.285775.4286
ENSG00000014641homo_sapiensENSP0000023311488.622877.8443neolamprologus_brichardiENSNBRP0000001337888.888978.0781
ENSG00000014641homo_sapiensENSP0000023311495.50989.521naja_najaENSNNAP0000002045195.223989.2537
ENSG00000014641homo_sapiensENSP0000023311496.706688.9222podarcis_muralisENSPMRP0000001031596.706688.9222
ENSG00000014641homo_sapiensENSP0000023311496.407290.1198geospiza_fortisENSGFOP0000001639596.696790.3904
ENSG00000014641homo_sapiensENSP0000023311496.407290.7186taeniopygia_guttataENSTGUP0000003264996.407290.7186
ENSG00000014641homo_sapiensENSP0000023311492.51581.1377erpetoichthys_calabaricusENSECRP0000002909192.51581.1377
ENSG00000014641homo_sapiensENSP0000023311490.718678.1437kryptolebias_marmoratusENSKMAP0000001919086.571474.5714
ENSG00000014641homo_sapiensENSP0000023311488.023975.1497kryptolebias_marmoratusENSKMAP0000002088188.023975.1497
ENSG00000014641homo_sapiensENSP0000023311494.01288.9222salvator_merianaeENSSMRP0000000670094.01288.9222
ENSG00000014641homo_sapiensENSP0000023311489.221676.6467oryzias_javanicusENSOJAP0000000362389.489576.8769
ENSG00000014641homo_sapiensENSP0000023311490.119877.5449oryzias_javanicusENSOJAP000000213968674
ENSG00000014641homo_sapiensENSP0000023311488.323477.5449amphilophus_citrinellusENSACIP0000001661186.510375.9531
ENSG00000014641homo_sapiensENSP0000023311489.52177.8443amphilophus_citrinellusENSACIP0000001252789.52177.8443
ENSG00000014641homo_sapiensENSP0000023311488.323476.9461dicentrarchus_labraxENSDLAP0000506936985.755874.7093
ENSG00000014641homo_sapiensENSP0000023311490.119878.1437dicentrarchus_labraxENSDLAP0000501237084.550673.3146
ENSG00000014641homo_sapiensENSP0000023311489.221677.2455amphiprion_perculaENSAPEP0000003337189.489577.4775
ENSG00000014641homo_sapiensENSP0000023311490.718677.5449amphiprion_perculaENSAPEP0000000973786.571474
ENSG00000014641homo_sapiensENSP0000023311488.622876.9461oryzias_sinensisENSOSIP0000001705188.888977.1772
ENSG00000014641homo_sapiensENSP0000023311489.820477.2455oryzias_sinensisENSOSIP0000005023978.12567.1875
ENSG00000014641homo_sapiensENSP0000023311497.00688.3234pelodiscus_sinensisENSPSIP0000001666997.00688.3234
ENSG00000014641homo_sapiensENSP0000023311497.00690.1198gopherus_evgoodeiENSGEVP0000500626697.00690.1198
ENSG00000014641homo_sapiensENSP0000023311497.305490.7186chelonoidis_abingdoniiENSCABP0000001315197.305490.7186
ENSG00000014641homo_sapiensENSP0000023311488.023976.9461seriola_dumeriliENSSDUP0000002837488.288377.1772
ENSG00000014641homo_sapiensENSP0000023311490.119878.4431seriola_dumeriliENSSDUP000000246378674.8571
ENSG00000014641homo_sapiensENSP0000023311488.922277.2455cottoperca_gobioENSCGOP0000003934288.656777.0149
ENSG00000014641homo_sapiensENSP0000023311489.52176.3473cottoperca_gobioENSCGOP0000000001585.428672.8571
ENSG00000014641homo_sapiensENSP0000023311497.00690.4192struthio_camelus_australisENSSCUP0000002274797.297390.6907
ENSG00000014641homo_sapiensENSP0000023311496.706690.4192anser_brachyrhynchusENSABRP0000000841896.706690.4192
ENSG00000014641homo_sapiensENSP0000023311489.221676.6467gasterosteus_aculeatusENSGACP0000000126887.647175.2941
ENSG00000014641homo_sapiensENSP0000023311489.52177.2455gasterosteus_aculeatusENSGACP0000002591589.789877.4775
ENSG00000014641homo_sapiensENSP0000023311488.023976.3473cynoglossus_semilaevisENSCSEP0000000179187.761276.1194
ENSG00000014641homo_sapiensENSP0000023311485.628774.8503cynoglossus_semilaevisENSCSEP0000001548590.506379.1139
ENSG00000014641homo_sapiensENSP0000023311488.622878.1437poecilia_formosaENSPFOP0000000179588.888978.3784
ENSG00000014641homo_sapiensENSP0000023311489.820478.1437poecilia_formosaENSPFOP0000000398990.090178.3784
ENSG00000014641homo_sapiensENSP0000023311489.820478.1437myripristis_murdjanENSMMDP0000502202985.470174.359
ENSG00000014641homo_sapiensENSP0000023311489.820476.9461myripristis_murdjanENSMMDP0000500393589.020876.2611
ENSG00000014641homo_sapiensENSP0000023311487.724576.6467sander_luciopercaENSSLUP0000004146286.430775.5162
ENSG00000014641homo_sapiensENSP0000023311489.820478.4431sander_luciopercaENSSLUP0000001958184.50773.8028
ENSG00000014641homo_sapiensENSP0000023311496.407290.1198strigops_habroptilaENSSHBP0000501733596.407290.1198
ENSG00000014641homo_sapiensENSP0000023311490.718677.5449amphiprion_ocellarisENSAOCP0000002688086.571474
ENSG00000014641homo_sapiensENSP0000023311489.221677.2455amphiprion_ocellarisENSAOCP0000002138589.489577.4775
ENSG00000014641homo_sapiensENSP0000023311497.305491.3174terrapene_carolina_triunguisENSTMTP0000001615897.305491.3174
ENSG00000014641homo_sapiensENSP0000023311480.538968.2635hucho_huchoENSHHUP0000007430370.23559.53
ENSG00000014641homo_sapiensENSP0000023311487.724576.6467hucho_huchoENSHHUP0000002526886.943675.9644
ENSG00000014641homo_sapiensENSP0000023311489.221677.2455hucho_huchoENSHHUP0000001648483.943772.6761
ENSG00000014641homo_sapiensENSP0000023311489.52177.2455betta_splendensENSBSLP0000002325385.919574.1379
ENSG00000014641homo_sapiensENSP0000023311488.922278.1437betta_splendensENSBSLP0000003925487.610676.9911
ENSG00000014641homo_sapiensENSP0000023311489.221677.8443pygocentrus_nattereriENSPNAP0000001941589.489578.0781
ENSG00000014641homo_sapiensENSP0000023311491.317480.5389pygocentrus_nattereriENSPNAP0000002866091.591680.7808
ENSG00000014641homo_sapiensENSP0000023311489.52178.4431anabas_testudineusENSATEP0000006326785.428674.8571
ENSG00000014641homo_sapiensENSP0000023311490.119878.1437anabas_testudineusENSATEP0000002845285.028373.7288
ENSG00000014641homo_sapiensENSP0000023311478.742566.4671ciona_savignyiENSCSAVP0000001893976.011664.1618
ENSG00000014641homo_sapiensENSP0000023311482.335370.0599seriola_lalandi_dorsalisENSSLDP0000002690883.586671.1246
ENSG00000014641homo_sapiensENSP0000023311488.323477.2455seriola_lalandi_dorsalisENSSLDP0000002264488.588677.4775
ENSG00000014641homo_sapiensENSP0000023311488.023976.3473labrus_bergyltaENSLBEP0000001136288.023976.3473
ENSG00000014641homo_sapiensENSP0000023311458.083841.018labrus_bergyltaENSLBEP000000034125035.3093
ENSG00000014641homo_sapiensENSP0000023311488.922277.8443pundamilia_nyerereiENSPNYP0000001106489.189278.0781
ENSG00000014641homo_sapiensENSP0000023311490.419279.3413pundamilia_nyerereiENSPNYP0000002432090.690779.5796
ENSG00000014641homo_sapiensENSP0000023311488.922277.2455mastacembelus_armatusENSMAMP0000004354886.588975.2187
ENSG00000014641homo_sapiensENSP0000023311489.52177.8443mastacembelus_armatusENSMAMP0000003424385.428674.2857
ENSG00000014641homo_sapiensENSP0000023311489.221677.5449stegastes_partitusENSSPAP0000000665089.489577.7778
ENSG00000014641homo_sapiensENSP0000023311491.01877.5449stegastes_partitusENSSPAP0000002249689.411876.1765
ENSG00000014641homo_sapiensENSP0000023311485.928175.7485oncorhynchus_tshawytschaENSOTSP0000503556481.534171.875
ENSG00000014641homo_sapiensENSP0000023311488.622877.5449oncorhynchus_tshawytschaENSOTSP0000503516884.571474
ENSG00000014641homo_sapiensENSP0000023311469.161759.5808oncorhynchus_tshawytschaENSOTSP0000503523871.739161.8012
ENSG00000014641homo_sapiensENSP0000023311485.029974.5509oncorhynchus_tshawytschaENSOTSP0000501893185.285374.7748
ENSG00000014641homo_sapiensENSP0000023311489.221677.8443acanthochromis_polyacanthusENSAPOP0000000378989.489578.0781
ENSG00000014641homo_sapiensENSP0000023311491.01877.5449acanthochromis_polyacanthusENSAPOP0000003336686.857174
ENSG00000014641homo_sapiensENSP0000023311496.706691.018aquila_chrysaetos_chrysaetosENSACCP0002000837896.706691.018
ENSG00000014641homo_sapiensENSP0000023311488.023975.1497nothobranchius_furzeriENSNFUP0001505163880.547968.7671
ENSG00000014641homo_sapiensENSP0000023311485.329373.9521nothobranchius_furzeriENSNFUP0001505012677.868967.4863
ENSG00000014641homo_sapiensENSP0000023311491.01878.1437cyprinodon_variegatusENSCVAP0000001364886.857174.5714
ENSG00000014641homo_sapiensENSP0000023311489.52178.4431cyprinodon_variegatusENSCVAP0000002209389.789878.6787
ENSG00000014641homo_sapiensENSP0000023311490.718680.5389denticeps_clupeoidesENSDCDP0000003320883.701774.3094
ENSG00000014641homo_sapiensENSP0000023311488.323476.6467denticeps_clupeoidesENSDCDP0000001881082.172771.3092
ENSG00000014641homo_sapiensENSP0000023311488.622876.6467larimichthys_croceaENSLCRP0000505442780.216869.3767
ENSG00000014641homo_sapiensENSP0000023311489.52177.2455larimichthys_croceaENSLCRP0000504987385.428673.7143
ENSG00000014641homo_sapiensENSP0000023311490.718678.7425takifugu_rubripesENSTRUP0000002220880.158769.5767
ENSG00000014641homo_sapiensENSP0000023311488.323476.0479takifugu_rubripesENSTRUP0000005834985.507273.6232
ENSG00000014641homo_sapiensENSP0000023311496.407291.018ficedula_albicollisENSFALP0000001418796.407291.018
ENSG00000014641homo_sapiensENSP0000023311487.724574.8503hippocampus_comesENSHCOP0000001203687.98875.0751
ENSG00000014641homo_sapiensENSP0000023311477.544965.8683hippocampus_comesENSHCOP0000001708389.930676.3889
ENSG00000014641homo_sapiensENSP0000023311490.119878.1437cyprinus_carpio_carpioENSCCRP0000015312084.550673.3146
ENSG00000014641homo_sapiensENSP0000023311489.820478.1437cyprinus_carpio_carpioENSCCRP0000011062585.714374.5714
ENSG00000014641homo_sapiensENSP0000023311484.730571.8563cyprinus_carpio_carpioENSCCRP0000005096980.397768.1818
ENSG00000014641homo_sapiensENSP0000023311489.52178.7425cyprinus_carpio_carpioENSCCRP0000015585974.937365.9148
ENSG00000014641homo_sapiensENSP0000023311496.706691.018coturnix_japonicaENSCJPP0000501404484.776979.79
ENSG00000014641homo_sapiensENSP0000023311489.52177.8443poecilia_latipinnaENSPLAP0000001073989.789878.0781
ENSG00000014641homo_sapiensENSP0000023311488.323477.8443poecilia_latipinnaENSPLAP0000002945588.323477.8443
ENSG00000014641homo_sapiensENSP0000023311465.568957.1856sinocyclocheilus_grahamiENSSGRP0000000792172.516663.245
ENSG00000014641homo_sapiensENSP0000023311490.119878.4431sinocyclocheilus_grahamiENSSGRP000000064078674.8571
ENSG00000014641homo_sapiensENSP0000023311489.221677.8443sinocyclocheilus_grahamiENSSGRP0000001479986.880575.8018
ENSG00000014641homo_sapiensENSP0000023311488.922277.8443maylandia_zebraENSMZEP0000503664677.545767.8851
ENSG00000014641homo_sapiensENSP0000023311489.221677.8443maylandia_zebraENSMZEP0000502042686.880575.8018
ENSG00000014641homo_sapiensENSP0000023311490.419279.3413maylandia_zebraENSMZEP0000502045786.285775.7143
ENSG00000014641homo_sapiensENSP0000023311485.329371.8563tetraodon_nigroviridisENSTNIP0000001272786.102772.5076
ENSG00000014641homo_sapiensENSP0000023311491.01879.3413tetraodon_nigroviridisENSTNIP0000000529391.291379.5796
ENSG00000014641homo_sapiensENSP0000023311488.922278.4431paramormyrops_kingsleyaeENSPKIP0000002073484.857174.8571
ENSG00000014641homo_sapiensENSP0000023311484.131773.9521paramormyrops_kingsleyaeENSPKIP0000001902185.151574.8485
ENSG00000014641homo_sapiensENSP0000023311491.616879.3413scleropages_formosusENSSFOP0001506844387.428675.7143
ENSG00000014641homo_sapiensENSP0000023311489.52178.7425scleropages_formosusENSSFOP0001503910586.167175.7925
ENSG00000014641homo_sapiensENSP0000023311490.119880.2395leptobrachium_leishanenseENSLLEP0000001213683.611174.4444
ENSG00000014641homo_sapiensENSP0000023311489.820477.5449scophthalmus_maximusENSSMAP0000005832784.985873.3711
ENSG00000014641homo_sapiensENSP0000023311487.125777.5449scophthalmus_maximusENSSMAP0000004287784.59375.2907
ENSG00000014641homo_sapiensENSP0000023311489.52176.6467oryzias_melastigmaENSOMEP0000002121789.789876.8769
ENSG00000014641homo_sapiensENSP0000023311490.119877.2455oryzias_melastigmaENSOMEP000000175168673.7143

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0004470enables malic enzyme activity1TASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005615located_in extracellular space1HDAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1IDAHomo_sapiens(9606)Component
GO:0005813located_in centrosome1IDAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0006094involved_in gluconeogenesis1TASHomo_sapiens(9606)Process
GO:0006099involved_in tricarboxylic acid cycle1IBAHomo_sapiens(9606)Process
GO:0006107involved_in oxaloacetate metabolic process1IBAHomo_sapiens(9606)Process
GO:0006108involved_in malate metabolic process1IBAHomo_sapiens(9606)Process
GO:0006734involved_in NADH metabolic process2IBA,IDAHomo_sapiens(9606)Process
GO:0006739involved_in NADP metabolic process1IDAHomo_sapiens(9606)Process
GO:0030060enables L-malate dehydrogenase activity2EXP,IBAHomo_sapiens(9606)Function
GO:0047860enables diiodophenylpyruvate reductase activity1IEAHomo_sapiens(9606)Function
GO:0047995enables hydroxyphenylpyruvate reductase activity1IEAHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component

Expression