Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000011590 Gene ID 27033 Accession 16763
Symbol ZBTB32 Alias Rog;FAXF;FAZF;TZFP;mynn;ZNF538 Full Name zinc finger and BTB domain containing 32
Status Confidence Length 12481 bases Strand Plus strand
Position 19 : 35704558 - 35717038 RNA binding domain zf-met
Summary Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; identical protein binding activity; and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000262630 zf-met PF12874 0.00031 1
ENSP00000376035 zf-met PF12874 0.00031 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ZBTB32-202 ENST00000392197 2037 487aa ENSP00000376035
ZBTB32-204 ENST00000442282 691 No protein -
ZBTB32-203 ENST00000426659 469 71aa ENSP00000466524
ZBTB32-205 ENST00000451726 355 No protein -
ZBTB32-201 ENST00000262630 1960 487aa ENSP00000262630
ZBTB32-206 ENST00000481182 1733 302aa ENSP00000433657

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000011590homo_sapiensENSP0000045571119.252911.7816homo_sapiensENSP0000037603513.75778.41889
ENSG00000011590homo_sapiensENSP0000024610422.149814.3322homo_sapiensENSP0000037603513.9639.03491
ENSG00000011590homo_sapiensENSP0000033815732.986623.9227homo_sapiensENSP0000037603545.585233.0595
ENSG00000011590homo_sapiensENSP0000031587022.040816.3265homo_sapiensENSP0000037603511.08838.21355
ENSG00000011590homo_sapiensENSP0000027659415.411611.2084homo_sapiensENSP0000037603518.069813.1417
ENSG00000011590homo_sapiensENSP0000029377114.47159.9187homo_sapiensENSP0000037603518.275212.5257
ENSG00000011590homo_sapiensENSP0000035809212.48487.27273homo_sapiensENSP0000037603521.149912.3203
ENSG00000011590homo_sapiensENSP000003597408.953825.08954homo_sapiensENSP0000037603519.507211.0883
ENSG00000011590homo_sapiensENSP0000037984713.32297.99373homo_sapiensENSP0000037603517.453810.4723
ENSG00000011590homo_sapiensENSP0000035153916.572511.6761homo_sapiensENSP0000037603518.069812.731
ENSG00000011590homo_sapiensENSP0000038472511.59668.40336homo_sapiensENSP0000037603514.168410.2669
ENSG00000011590homo_sapiensENSP0000044633518.095210.7143homo_sapiensENSP0000037603515.60579.24025
ENSG00000011590homo_sapiensENSP0000030548315.992311.368homo_sapiensENSP0000037603517.043112.115
ENSG00000011590homo_sapiensENSP000003621279.960166.1089homo_sapiensENSP0000037603515.40049.44559
ENSG00000011590homo_sapiensENSP0000032796820.205513.3562homo_sapiensENSP0000037603512.1158.00821
ENSG00000011590homo_sapiensENSP0000002094525.373115.6716homo_sapiensENSP0000037603513.9638.62423
ENSG00000011590homo_sapiensENSP0000047785815.266110.7843homo_sapiensENSP0000037603522.381915.8111
ENSG00000011590homo_sapiensENSP0000030277011.15796.94737homo_sapiensENSP0000037603510.8836.77618
ENSG00000011590homo_sapiensENSP000003563226.815644.46927homo_sapiensENSP0000037603512.52578.21355
ENSG00000011590homo_sapiensENSP000003538638.438295.54156homo_sapiensENSP0000037603513.75779.03491
ENSG00000011590homo_sapiensENSP0000036306414.03518.94737homo_sapiensENSP0000037603516.427110.4723
ENSG00000011590homo_sapiensENSP0000050156114.43998.63698homo_sapiensENSP0000037603521.971313.1417
ENSG00000011590homo_sapiensENSP0000046787716.47829.8546homo_sapiensENSP0000037603520.944612.5257
ENSG00000011590homo_sapiensENSP0000026626911.35377.86026homo_sapiensENSP0000037603516.016411.0883
ENSG00000011590homo_sapiensENSP0000050746212.99348.88158homo_sapiensENSP0000037603516.221811.0883
ENSG00000011590homo_sapiensENSP0000046233712.85997.29367homo_sapiensENSP0000037603513.75777.80287
ENSG00000011590homo_sapiensENSP0000045176313.80758.78661homo_sapiensENSP0000037603513.55248.62423
ENSG00000011590homo_sapiensENSP0000031336214.46548.38574homo_sapiensENSP0000037603514.16848.21355
ENSG00000011590homo_sapiensENSP0000033903011.75447.54386homo_sapiensENSP0000037603513.75778.82957
ENSG00000011590homo_sapiensENSP0000040910718.009513.0332homo_sapiensENSP0000037603515.605711.2936
ENSG00000011590homo_sapiensENSP0000050691112.2027.99439homo_sapiensENSP0000037603517.864511.7043
ENSG00000011590homo_sapiensENSP000003541188.910035.79585homo_sapiensENSP0000037603521.149913.7577
ENSG00000011590homo_sapiensENSP0000038531917.723611.7073homo_sapiensENSP0000037603522.381914.7844
ENSG00000011590homo_sapiensENSP0000024405021.969714.7727homo_sapiensENSP0000037603511.90978.00821
ENSG00000011590homo_sapiensENSP0000046908917.416811.7417homo_sapiensENSP0000037603518.275212.3203
ENSG00000011590homo_sapiensENSP0000041583613.51798.63192homo_sapiensENSP0000037603517.043110.883

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000011590homo_sapiensENSP0000037603598.357397.7413nomascus_leucogenysENSNLEP0000001373298.357397.7413
ENSG00000011590homo_sapiensENSP0000037603598.973398.9733pan_paniscusENSPPAP0000001618998.973398.9733
ENSG00000011590homo_sapiensENSP0000037603598.357397.5359pongo_abeliiENSPPYP0000001105698.357397.5359
ENSG00000011590homo_sapiensENSP0000037603598.562698.5626pan_troglodytesENSPTRP0000001858898.562698.5626
ENSG00000011590homo_sapiensENSP0000037603595.482595.0719gorilla_gorillaENSGGOP0000001638395.286994.8771
ENSG00000011590homo_sapiensENSP0000037603555.030851.7454choloepus_hoffmanniENSCHOP0000000089655.371952.0661
ENSG00000011590homo_sapiensENSP0000037603548.049345.5852erinaceus_europaeusENSEEUP0000000436848.547746.0581
ENSG00000011590homo_sapiensENSP0000037603589.938487.0637callithrix_jacchusENSCJAP0000001861790.871487.9668
ENSG00000011590homo_sapiensENSP0000037603597.330695.2772cercocebus_atysENSCATP0000000623397.330695.2772
ENSG00000011590homo_sapiensENSP0000037603597.330695.2772macaca_mulattaENSMMUP0000000318297.330695.2772
ENSG00000011590homo_sapiensENSP0000037603597.125395.2772macaca_nemestrinaENSMNEP0000002632197.125395.2772
ENSG00000011590homo_sapiensENSP0000037603597.741395.8932papio_anubisENSPANP0000000178397.741395.8932
ENSG00000011590homo_sapiensENSP0000037603596.919994.2505mandrillus_leucophaeusENSMLEP0000000561996.919994.2505
ENSG00000011590homo_sapiensENSP0000037603561.19158.9322tursiops_truncatusENSTTRP0000000208960.692558.4521
ENSG00000011590homo_sapiensENSP0000037603582.956978.0287vulpes_vulpesENSVVUP0000002048780.478175.6972
ENSG00000011590homo_sapiensENSP0000037603574.53868.5832mus_spretusMGP_SPRETEiJ_P008206778.401772.1382
ENSG00000011590homo_sapiensENSP0000037603575.15469.6099equus_asinusENSEASP0000500141975.619870.0413
ENSG00000011590homo_sapiensENSP0000037603583.162277.2074capra_hircusENSCHIP0000000209882.653176.7347
ENSG00000011590homo_sapiensENSP0000037603579.466174.9487loxodonta_africanaENSLAFP0000001571081.645677.0042
ENSG00000011590homo_sapiensENSP0000037603581.930274.7433panthera_leoENSPLOP0000002179481.930274.7433
ENSG00000011590homo_sapiensENSP0000037603585.010379.4661ailuropoda_melanoleucaENSAMEP0000000061084.836179.3033
ENSG00000011590homo_sapiensENSP0000037603582.546276.7967bos_indicus_hybridENSBIXP0000500296976.280870.9677
ENSG00000011590homo_sapiensENSP0000037603579.055472.4846oryctolagus_cuniculusENSOCUP0000001097278.893472.3361
ENSG00000011590homo_sapiensENSP0000037603553.182847.4333equus_caballusENSECAP0000000406072.54964.7059
ENSG00000011590homo_sapiensENSP0000037603582.956978.0287canis_lupus_familiarisENSCAFP0084500261383.127678.1893
ENSG00000011590homo_sapiensENSP0000037603581.724874.538panthera_pardusENSPPRP0000001560981.724874.538
ENSG00000011590homo_sapiensENSP0000037603583.367677.0021marmota_marmota_marmotaENSMMMP0000000629382.520376.2195
ENSG00000011590homo_sapiensENSP0000037603586.03779.2608balaenoptera_musculusENSBMSP0001003055785.336178.6151
ENSG00000011590homo_sapiensENSP0000037603581.724874.538felis_catusENSFCAP0000002705381.724874.538
ENSG00000011590homo_sapiensENSP0000037603584.599679.0554ursus_americanusENSUAMP0000002676684.426278.8934
ENSG00000011590homo_sapiensENSP0000037603582.546276.7967bison_bison_bisonENSBBBP0000002709182.040876.3265
ENSG00000011590homo_sapiensENSP0000037603583.778277.6181monodon_monocerosENSMMNP0001500005182.926876.8293
ENSG00000011590homo_sapiensENSP0000037603581.108874.7433sus_scrofaENSSSCP0000003636682.809276.3103
ENSG00000011590homo_sapiensENSP0000037603587.063782.7515microcebus_murinusENSMICP0000004215786.178981.9106
ENSG00000011590homo_sapiensENSP0000037603582.340977.0021ovis_aries_rambouilletENSOARP0002002433681.836776.5306
ENSG00000011590homo_sapiensENSP0000037603544.763942.9158ursus_maritimusENSUMAP0000002788387.903284.2742
ENSG00000011590homo_sapiensENSP0000037603567.351160.7803ochotona_princepsENSOPRP0000000121467.489760.9053
ENSG00000011590homo_sapiensENSP0000037603584.188978.4394delphinapterus_leucasENSDLEP0000000345483.333377.6423
ENSG00000011590homo_sapiensENSP0000037603585.215679.0554physeter_catodonENSPCTP0000503130984.178578.0933
ENSG00000011590homo_sapiensENSP0000037603574.53868.5832mus_caroliMGP_CAROLIEiJ_P007874678.064571.828
ENSG00000011590homo_sapiensENSP0000037603574.53868.5832mus_musculusENSMUSP0000010378678.064571.828
ENSG00000011590homo_sapiensENSP0000037603579.671573.922mustela_putorius_furoENSMPUP0000000618183.440977.4194
ENSG00000011590homo_sapiensENSP0000037603591.375889.117aotus_nancymaaeENSANAP0000003285691.563889.3004
ENSG00000011590homo_sapiensENSP0000037603576.591473.306saimiri_boliviensis_boliviensisENSSBOP0000003654686.744283.0233
ENSG00000011590homo_sapiensENSP0000037603591.581188.501saimiri_boliviensis_boliviensisENSSBOP0000001786192.148889.0496
ENSG00000011590homo_sapiensENSP0000037603598.357396.3039chlorocebus_sabaeusENSCSAP0000000073798.357396.3039
ENSG00000011590homo_sapiensENSP0000037603583.367676.5914tupaia_belangeriENSTBEP0000000562183.711376.9072
ENSG00000011590homo_sapiensENSP0000037603518.891218.2752mesocricetus_auratusENSMAUP0000002392391.089188.1188
ENSG00000011590homo_sapiensENSP0000037603585.420979.2608phocoena_sinusENSPSNP0000001969184.552878.4553
ENSG00000011590homo_sapiensENSP0000037603585.420979.2608camelus_dromedariusENSCDRP0000502148484.552878.4553
ENSG00000011590homo_sapiensENSP0000037603583.983679.0554carlito_syrichtaENSTSYP0000000814183.983679.0554
ENSG00000011590homo_sapiensENSP0000037603581.930274.7433panthera_tigris_altaicaENSPTIP0000002522081.930274.7433
ENSG00000011590homo_sapiensENSP0000037603575.359369.1992rattus_norvegicusENSRNOP0000005922275.983469.7723
ENSG00000011590homo_sapiensENSP0000037603586.447681.1088prolemur_simusENSPSMP0000000076585.050579.798
ENSG00000011590homo_sapiensENSP0000037603573.716667.3511microtus_ochrogasterENSMOCP0000000518877.204370.5376
ENSG00000011590homo_sapiensENSP0000037603576.180769.4045peromyscus_maniculatus_bairdiiENSPEMP0000002080879.613772.5322
ENSG00000011590homo_sapiensENSP0000037603582.546276.7967bos_mutusENSBMUP0000002282582.040876.3265
ENSG00000011590homo_sapiensENSP0000037603574.127368.1725mus_spicilegusENSMSIP0000000734877.634471.3979
ENSG00000011590homo_sapiensENSP0000037603572.073966.3244cricetulus_griseus_chok1gshdENSCGRP0000101847577.654971.4602
ENSG00000011590homo_sapiensENSP0000037603578.439472.0739pteropus_vampyrusENSPVAP0000001209483.771976.9737
ENSG00000011590homo_sapiensENSP0000037603582.340975.77myotis_lucifugusENSMLUP0000001038681.338774.8479
ENSG00000011590homo_sapiensENSP0000037603582.956977.0021rhinolophus_ferrumequinumENSRFEP0001001592283.643977.6398
ENSG00000011590homo_sapiensENSP0000037603582.340976.1807neovison_visonENSNVIP0000002251483.19576.971
ENSG00000011590homo_sapiensENSP0000037603582.546276.7967bos_taurusENSBTAP0000003221782.208676.4826
ENSG00000011590homo_sapiensENSP0000037603580.698275.5647heterocephalus_glaber_femaleENSHGLP0000002193781.366576.1905
ENSG00000011590homo_sapiensENSP0000037603597.535995.2772rhinopithecus_bietiENSRBIP0000002637897.736695.4733
ENSG00000011590homo_sapiensENSP0000037603582.956978.0287canis_lupus_dingoENSCAFP0002002359683.127678.1893
ENSG00000011590homo_sapiensENSP0000037603581.519575.77sciurus_vulgarisENSSVLP0000501266982.88177.0355
ENSG00000011590homo_sapiensENSP0000037603566.735162.423procavia_capensisENSPCAP0000000421766.462262.1677
ENSG00000011590homo_sapiensENSP0000037603519.301818.6858nannospalax_galiliENSNGAP0000000613293.069390.099
ENSG00000011590homo_sapiensENSP0000037603582.546276.7967bos_grunniensENSBGRP0000003971682.040876.3265
ENSG00000011590homo_sapiensENSP0000037603583.983678.8501cervus_hanglu_yarkandensisENSCHYP0000001040668.509264.3216
ENSG00000011590homo_sapiensENSP0000037603583.983677.0021catagonus_wagneriENSCWAP0000000660884.504177.4793
ENSG00000011590homo_sapiensENSP0000037603586.03781.5195otolemur_garnettiiENSOGAP0000000370585.336180.8554
ENSG00000011590homo_sapiensENSP0000037603591.170488.2957cebus_imitatorENSCCAP0000000014191.735588.843
ENSG00000011590homo_sapiensENSP0000037603579.876873.922urocitellus_parryiiENSUPAP0001001475982.76676.5957
ENSG00000011590homo_sapiensENSP0000037603581.930277.2074moschus_moschiferusENSMMSP0000000274682.608777.8468
ENSG00000011590homo_sapiensENSP0000037603518.685817.8645mus_pahariMGP_PahariEiJ_P001562390.09986.1386
ENSG00000011590homo_sapiensENSP0000037603587.88583.1622propithecus_coquereliENSPCOP0000000096686.991982.3171
ENSG00000011590homo_sapiensENSP0000037603534.291618.8912clupea_harengusENSCHAP0000003016724.925413.7313
ENSG00000011590homo_sapiensENSP0000037603537.57722.1766danio_rerioENSDARP0000001647122.648513.3663
ENSG00000011590homo_sapiensENSP0000037603537.987722.3819carassius_auratusENSCARP0000009601422.235613.101
ENSG00000011590homo_sapiensENSP0000037603536.96122.1766carassius_auratusENSCARP0000008421921.226412.7358
ENSG00000011590homo_sapiensENSP0000037603536.96119.9179astyanax_mexicanusENSAMXP0000000842723.285912.5485
ENSG00000011590homo_sapiensENSP0000037603537.57720.7392ictalurus_punctatusENSIPUP0000002523919.122310.5538
ENSG00000011590homo_sapiensENSP0000037603536.96120.7392electrophorus_electricusENSEEEP0000004691424.193513.5753
ENSG00000011590homo_sapiensENSP0000037603527.720716.2218oncorhynchus_mykissENSOMYP0000008722631.914918.6761
ENSG00000011590homo_sapiensENSP0000037603525.46214.7844salmo_truttaENSSTUP0000003779029.523817.1429
ENSG00000011590homo_sapiensENSP000003760356.776184.72279amphilophus_citrinellusENSACIP0000001262135.869625
ENSG00000011590homo_sapiensENSP000003760357.597545.54415gasterosteus_aculeatusENSGACP0000001673736.274526.4706
ENSG00000011590homo_sapiensENSP0000037603528.542117.8645amphiprion_ocellarisENSAOCP0000001818526.127816.3534
ENSG00000011590homo_sapiensENSP0000037603536.755620.9446pygocentrus_nattereriENSPNAP0000000190022.572512.8625
ENSG00000011590homo_sapiensENSP0000037603528.131416.2218oncorhynchus_tshawytschaENSOTSP0000503447532.235318.5882
ENSG00000011590homo_sapiensENSP0000037603536.96121.5606cyprinus_carpio_carpioENSCCRP0000016485421.003512.252
ENSG00000011590homo_sapiensENSP0000037603537.782321.5606cyprinus_carpio_carpioENSCCRP0000006476520.399111.6408
ENSG00000011590homo_sapiensENSP0000037603537.57722.1766sinocyclocheilus_grahamiENSSGRP0000000202221.605712.7509
ENSG00000011590homo_sapiensENSP000003760356.776183.6961sinocyclocheilus_grahamiENSSGRP0000007176536.263719.7802
ENSG00000011590homo_sapiensENSP0000037603527.720716.6324maylandia_zebraENSMZEP0000503696031.034518.6207
ENSG00000011590homo_sapiensENSP0000037603528.336816.0164oryzias_melastigmaENSOMEP0000002557129.361716.5957

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II2IBA,IDAHomo_sapiens(9606)Process
GO:0000785part_of chromatin1ISAHomo_sapiens(9606)Component
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0000981enables DNA-binding transcription factor activity, RNA polymerase II-specific1ISAHomo_sapiens(9606)Function
GO:0001227enables DNA-binding transcription repressor activity, RNA polymerase II-specific2IBA,IDAHomo_sapiens(9606)Function
GO:0001817involved_in regulation of cytokine production1IBAHomo_sapiens(9606)Process
GO:0002682involved_in regulation of immune system process1IBAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1ISSHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654is_active_in nucleoplasm1IBAHomo_sapiens(9606)Component
GO:0008270enables zinc ion binding1ISSHomo_sapiens(9606)Function
GO:1990837enables sequence-specific double-stranded DNA binding1IDAHomo_sapiens(9606)Function

Expression