RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	TF
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000010803	Gene ID	22955	Accession	19003
Symbol	SCMH1	Alias	Scml3	Full Name	Scm polycomb group protein homolog 1
Status	Confidence	Length	215105 bases	Strand	Minus strand
Position	1 : 41027202 - 41242306	RNA binding domain	RBR
Summary	Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to act upstream of or within anterior/posterior pattern specification; chromatin remodeling; and spermatogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000403974	RBR	PF17208	1.8e-12	1
ENSP00000361677	RBR	PF17208	2.3e-12	1
ENSP00000361678	RBR	PF17208	2.4e-12	1
ENSP00000361676	RBR	PF17208	2.4e-12	1
ENSP00000511815	RBR	PF17208	2.6e-12	1
ENSP00000337352	RBR	PF17208	2.8e-12	1
ENSP00000318094	RBR	PF17208	2.9e-12	1
ENSP00000511813	RBR	PF17208	2.9e-12	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
SCMH1-201	ENST00000326197	3275	660aa	ENSP00000318094
SCMH1-203	ENST00000372595	3231	599aa	ENSP00000361676
SCMH1-202	ENST00000337495	3108	648aa	ENSP00000337352
SCMH1-204	ENST00000372596	3323	577aa	ENSP00000361677
SCMH1-205	ENST00000372597	3252	591aa	ENSP00000361678
SCMH1-213	ENST00000695335	3370	670aa	ENSP00000511813
SCMH1-208	ENST00000472037	735	141aa	ENSP00000479881
SCMH1-214	ENST00000695336	2694	550aa	ENSP00000511814
SCMH1-206	ENST00000456518	1586	480aa	ENSP00000403974
SCMH1-207	ENST00000460215	447	No protein	-
SCMH1-212	ENST00000498793	583	No protein	-
SCMH1-215	ENST00000695337	1994	559aa	ENSP00000511815
SCMH1-211	ENST00000489421	687	No protein	-
SCMH1-209	ENST00000482530	574	No protein	-
SCMH1-210	ENST00000488592	363	No protein	-

Gene Model

Click here to download ENSG00000010803's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
44450	Platelet Function Tests	2.2204460E-016	-
44527	Platelet Function Tests	2.2204460E-016	-
67876	Body Height	2E-20	25282103
98934	Body Height	2E-8	18391952
102745	Body Height	3E-9	23563607

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000010803's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003682	enables chromatin binding	1	IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0031507	involved_in heterochromatin formation	1	ISS	Homo_sapiens(9606)	Process
GO:0042393	enables histone binding	1	IBA	Homo_sapiens(9606)	Function
GO:0045892	involved_in negative regulation of DNA-templated transcription	2	IBA,NAS	Homo_sapiens(9606)	Process

Expression