RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	TF
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000008441	Gene ID	4784	Accession	7788
Symbol	NFIX	Alias	CTF;NF1A;MALNS;NF1-X;MRSHSS;NF-I/X;SOTOS2	Full Name	nuclear factor I X
Status	Confidence	Length	103322 bases	Strand	Plus strand
Position	19 : 12995475 - 13098796	RNA binding domain	N.A.
Summary	The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
33693090	Unique Mechanism by Which TGFBR1 Variants Cause 2 Distinct System Diseases　- Loeys-Dietz Syndrome and Multiple Self-Healing Squamous Epithelioma.	Takayuki Fujiwara	2019-11-02	Circulation reports
31889903	LINC00511 accelerated the process of gastric cancer by targeting miR-625-5p/NFIX axis.	Zhaosheng Chen	2019-01-01	Cancer cell international

Name	Transcript ID	bp	Protein	Translation ID
NFIX-214	ENST00000592199	6019	502aa	ENSP00000467512
NFIX-203	ENST00000397661	3143	441aa	ENSP00000380781
NFIX-212	ENST00000590027	579	128aa	ENSP00000465616
NFIX-204	ENST00000585382	1083	101aa	ENSP00000466605
NFIX-209	ENST00000587760	1487	433aa	ENSP00000466389
NFIX-205	ENST00000585575	1485	494aa	ENSP00000468794
NFIX-202	ENST00000360105	5459	403aa	ENSP00000353219
NFIX-210	ENST00000588228	1692	455aa	ENSP00000466735
NFIX-216	ENST00000676441	1692	510aa	ENSP00000502554
NFIX-206	ENST00000586797	1615	59aa	ENSP00000467536
NFIX-213	ENST00000591028	582	183aa	ENSP00000465094
NFIX-207	ENST00000586873	587	125aa	ENSP00000468707
NFIX-201	ENST00000358552	1589	460aa	ENSP00000351354
NFIX-215	ENST00000622520	1394	393aa	ENSP00000481181
NFIX-208	ENST00000587260	1537	440aa	ENSP00000467785
NFIX-217	ENST00000693124	918	293aa	ENSP00000509710
NFIX-211	ENST00000588680	319	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
72385	Bipolar Disorder	6E-10	28115744
75828	Body Mass Index	2E-6	25673413
94505	Education	2E-8	27225129

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000122	involved_in negative regulation of transcription by RNA polymerase II	1	IDA	Homo_sapiens(9606)	Process
GO:0000785	part_of chromatin	1	ISA	Homo_sapiens(9606)	Component
GO:0000978	enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0000981	enables DNA-binding transcription factor activity, RNA polymerase II-specific	2	IBA,ISA	Homo_sapiens(9606)	Function
GO:0003700	enables DNA-binding transcription factor activity	1	TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0006260	involved_in DNA replication	1	IEA	Homo_sapiens(9606)	Process
GO:0006357	involved_in regulation of transcription by RNA polymerase II	1	IBA	Homo_sapiens(9606)	Process
GO:0006366	involved_in transcription by RNA polymerase II	1	TAS	Homo_sapiens(9606)	Process
GO:0045944	involved_in positive regulation of transcription by RNA polymerase II	1	IDA	Homo_sapiens(9606)	Process
GO:1990837	enables sequence-specific double-stranded DNA binding	1	IDA	Homo_sapiens(9606)	Function