RBP Type	Non-canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Kinase
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000008128	Gene ID	728642	Accession	1730
Symbol	CDK11A	Alias	CDC2L2;CDC2L3;p58GTA;PITSLRE;CDK11-p46;CDK11-p58;CDK11-p110	Full Name	cyclin dependent kinase 11A
Status	Confidence	Length	21979 bases	Strand	Minus strand
Position	1 : 1702379 - 1724357	RNA binding domain	N.A.
Summary	This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
CDK11A-208	ENST00000404249	2984	780aa	ENSP00000384442
CDK11A-201	ENST00000356200	2653	746aa	ENSP00000348529
CDK11A-210	ENST00000463652	1028	No protein	-
CDK11A-202	ENST00000356937	2275	No protein	-
CDK11A-206	ENST00000378638	2429	746aa	ENSP00000367905
CDK11A-223	ENST00000509982	2306	420aa	ENSP00000422149
CDK11A-203	ENST00000357760	2446	779aa	ENSP00000350403
CDK11A-204	ENST00000358779	2419	770aa	ENSP00000351629
CDK11A-205	ENST00000378633	2458	783aa	ENSP00000367900
CDK11A-209	ENST00000460465	2333	407aa	ENSP00000462289
CDK11A-215	ENST00000478901	931	No protein	-
CDK11A-212	ENST00000468397	836	No protein	-
CDK11A-219	ENST00000491311	626	No protein	-
CDK11A-221	ENST00000495016	286	No protein	-
CDK11A-213	ENST00000468800	897	No protein	-
CDK11A-211	ENST00000464748	381	No protein	-
CDK11A-218	ENST00000489300	577	No protein	-
CDK11A-220	ENST00000492390	976	No protein	-
CDK11A-214	ENST00000474916	752	No protein	-
CDK11A-216	ENST00000479362	700	151aa	ENSP00000423900
CDK11A-222	ENST00000498810	574	No protein	-
CDK11A-217	ENST00000487462	437	No protein	-
CDK11A-207	ENST00000401096	450	37aa	ENSP00000383874

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000278	involved_in mitotic cell cycle	1	NAS	Homo_sapiens(9606)	Process
GO:0001558	involved_in regulation of cell growth	1	IEP	Homo_sapiens(9606)	Process
GO:0004672	enables protein kinase activity	1	NAS	Homo_sapiens(9606)	Function
GO:0004674	enables protein serine/threonine kinase activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IDA	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IEA	Homo_sapiens(9606)	Component
GO:0006355	involved_in regulation of DNA-templated transcription	1	NAS	Homo_sapiens(9606)	Process
GO:0006468	involved_in protein phosphorylation	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0006915	involved_in apoptotic process	1	NAS	Homo_sapiens(9606)	Process
GO:0007346	involved_in regulation of mitotic cell cycle	1	IBA	Homo_sapiens(9606)	Process
GO:0050684	involved_in regulation of mRNA processing	1	IDA	Homo_sapiens(9606)	Process
GO:0106310	enables protein serine kinase activity	1	IEA	Homo_sapiens(9606)	Function