RBP Type	Non-canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000004864	Gene ID	10165	Accession	10983
Symbol	SLC25A13	Alias	CTLN2;NICCD;CITRIN;ARALAR2	Full Name	solute carrier family 25 member 13
Status	Confidence	Length	201928 bases	Strand	Minus strand
Position	7 : 96120220 - 96322147	RNA binding domain	N.A.
Summary	This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
SLC25A13-201	ENST00000265631	3141	675aa	ENSP00000265631
SLC25A13-208	ENST00000494085	766	No protein	-
SLC25A13-206	ENST00000490072	578	No protein	-
SLC25A13-204	ENST00000484495	540	No protein	-
SLC25A13-207	ENST00000492869	433	No protein	-
SLC25A13-203	ENST00000472162	568	73aa	ENSP00000473505
SLC25A13-205	ENST00000487710	201	No protein	-
SLC25A13-202	ENST00000416240	3192	676aa	ENSP00000400101

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000514	enables 3-sulfino-L-alanine: proton, glutamate antiporter activity	1	IDA	Homo_sapiens(9606)	Function
GO:0000515	enables aspartate:glutamate, proton antiporter activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005313	enables L-glutamate transmembrane transporter activity	1	IBA	Homo_sapiens(9606)	Function
GO:0005509	enables calcium ion binding	1	IDA	Homo_sapiens(9606)	Function
GO:0005739	located_in mitochondrion	1	IDA	Homo_sapiens(9606)	Component
GO:0005743	located_in mitochondrial inner membrane	3	IDA,ISS,TAS	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	NAS	Homo_sapiens(9606)	Component
GO:0006094	involved_in gluconeogenesis	1	TAS	Homo_sapiens(9606)	Process
GO:0006754	involved_in ATP biosynthetic process	1	IDA	Homo_sapiens(9606)	Process
GO:0006839	involved_in mitochondrial transport	1	NAS	Homo_sapiens(9606)	Process
GO:0009066	involved_in aspartate family amino acid metabolic process	1	TAS	Homo_sapiens(9606)	Process
GO:0015172	enables acidic amino acid transmembrane transporter activity	1	EXP	Homo_sapiens(9606)	Function
GO:0015183	enables L-aspartate transmembrane transporter activity	1	IBA	Homo_sapiens(9606)	Function
GO:0015804	involved_in neutral amino acid transport	1	IEA	Homo_sapiens(9606)	Process
GO:0015810	involved_in aspartate transmembrane transport	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0015813	involved_in L-glutamate transmembrane transport	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IDA	Homo_sapiens(9606)	Function
GO:0043490	involved_in malate-aspartate shuttle	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0045333	involved_in cellular respiration	1	IDA	Homo_sapiens(9606)	Process
GO:0051592	involved_in response to calcium ion	1	IDA	Homo_sapiens(9606)	Process
GO:0070778	involved_in L-aspartate transmembrane transport	1	IEA	Homo_sapiens(9606)	Process
GO:0072337	involved_in modified amino acid transport	1	IEA	Homo_sapiens(9606)	Process
GO:1902600	involved_in proton transmembrane transport	1	IEA	Homo_sapiens(9606)	Process