RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Description

Ensembl ID	FBgn0260634	Gene ID	42819	Accession	-
Symbol	eIF4G2	Alias	CG10192;DmelCG10192;eIF4G;eIF4G-2;ms(3)nc32;nc32;ofs	Full Name	eukaryotic translation initiation factor 4G2
Status	Confidence	Length	10953 bases	Strand	Minus strand
Position	3R : 23808285 - 23819237	RNA binding domain	MIF4G , MA3
Summary	Enables RNA 7-methylguanosine cap binding activity. Involved in male meiotic nuclear division and spermatogenesis. Predicted to be part of eukaryotic translation initiation factor 4F complex. Is expressed in adult head; cyst cell of testis; male germline cell; and spermatocyte. Orthologous to human EIF4G3 (eukaryotic translation initiation factor 4 gamma 3). [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
FBpp0088566	MA3	PF02847	2e-24	1
FBpp0088566	MIF4G	PF02854	8.5e-59	2
FBpp0310717	MA3	PF02847	2e-24	1
FBpp0310717	MIF4G	PF02854	8.5e-59	2

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
-	FBtr0344335	8889	2072aa	FBpp0310717
-	FBtr0089623	7297	2072aa	FBpp0088566

Gene Model

Click here to download FBgn0260634's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download FBgn0260634's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
FBgn0260634	drosophila_melanogaster	FBpp0306828	25.4704	12.7016	drosophila_melanogaster	FBpp0310717	18.2915	9.12162
FBgn0260634	drosophila_melanogaster	FBpp0111817	42.6264	24.3356	drosophila_melanogaster	FBpp0310717	39.4788	22.5386

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
FBgn0260634	drosophila_melanogaster	FBpp0310717	17.8089	8.68726	caenorhabditis_elegans	M110.4e.1	31.8103	15.5172
FBgn0260634	drosophila_melanogaster	FBpp0310717	7.62548	4.39189	eptatretus_burgeri	ENSEBUP00000009485	42.246	24.3316
FBgn0260634	drosophila_melanogaster	FBpp0310717	6.32239	2.99228	eptatretus_burgeri	ENSEBUP00000008010	39.577	18.7311
FBgn0260634	drosophila_melanogaster	FBpp0310717	8.39768	4.68147	eptatretus_burgeri	ENSEBUP00000012521	42.963	23.9506
FBgn0260634	drosophila_melanogaster	FBpp0310717	4.34363	2.26834	eptatretus_burgeri	ENSEBUP00000023589	43.0622	22.488
FBgn0260634	drosophila_melanogaster	FBpp0310717	7.04633	2.79923	ciona_intestinalis	ENSCINP00000010674	34.192	13.5831
FBgn0260634	drosophila_melanogaster	FBpp0310717	15.5405	8.44595	ciona_savignyi	ENSCSAVP00000018002	37.6168	20.4439

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000340	enables RNA 7-methylguanosine cap binding	1	IDA	Drosophila_melanogaster(7227)	Function
GO:0003723	enables RNA binding	1	IEA	Drosophila_melanogaster(7227)	Function
GO:0003729	enables mRNA binding	1	IBA	Drosophila_melanogaster(7227)	Function
GO:0003743	enables translation initiation factor activity	2	IBA,IEA	Drosophila_melanogaster(7227)	Function
GO:0007140	involved_in male meiotic nuclear division	1	IMP	Drosophila_melanogaster(7227)	Process
GO:0007283	involved_in spermatogenesis	1	IMP	Drosophila_melanogaster(7227)	Process
GO:0016281	part_of eukaryotic translation initiation factor 4F complex	1	IBA	Drosophila_melanogaster(7227)	Component

Expression