RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Description

Ensembl ID	FBgn0035942	Gene ID	39023	Accession	-
Symbol	ValRS-m	Alias	CG5660;DmelCG5660	Full Name	Valyl-tRNA synthetase, mitochondrial
Status	Confidence	Length	3496 bases	Strand	Minus strand
Position	3L : 8961274 - 8964769	RNA binding domain	tRNA-synt_1g , tRNA-synt_1 , Anticodon_1
Summary	Predicted to enable valine-tRNA ligase activity. Predicted to be involved in valyl-tRNA aminoacylation. Predicted to be located in mitochondrion. Predicted to be active in cytosol. Is expressed in several structures, including adult head; embryonic/larval muscle system; gut section; and spermatozoon. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 20. Orthologous to human VARS1 (valyl-tRNA synthetase 1) and VARS2 (valyl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
FBpp0076287	tRNA-synt_1g	PF09334	6.5e-14	1
FBpp0076287	Anticodon_1	PF08264	1.6e-25	2
FBpp0076287	tRNA-synt_1	PF00133	3.1e-172	3
FBpp0312160	tRNA-synt_1g	PF09334	6.5e-14	1
FBpp0312160	Anticodon_1	PF08264	1.6e-25	2
FBpp0312160	tRNA-synt_1	PF00133	3.1e-172	3

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
-	FBtr0346542	3254	994aa	FBpp0312160
-	FBtr0076560	3148	994aa	FBpp0076287

Gene Model

Click here to download FBgn0035942's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download FBgn0035942's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
FBgn0035942

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
FBgn0035942

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000166	enables nucleotide binding	1	IEA	Drosophila_melanogaster(7227)	Function
GO:0002161	enables aminoacyl-tRNA editing activity	1	IEA	Drosophila_melanogaster(7227)	Function
GO:0004812	enables aminoacyl-tRNA ligase activity	1	IEA	Drosophila_melanogaster(7227)	Function
GO:0004832	enables valine-tRNA ligase activity	3	IBA,IEA,TAS	Drosophila_melanogaster(7227)	Function
GO:0005524	enables ATP binding	1	IEA	Drosophila_melanogaster(7227)	Function
GO:0005739	located_in mitochondrion	1	TAS	Drosophila_melanogaster(7227)	Component
GO:0005829	is_active_in cytosol	1	IBA	Drosophila_melanogaster(7227)	Component
GO:0006418	involved_in tRNA aminoacylation for protein translation	1	IEA	Drosophila_melanogaster(7227)	Process
GO:0006438	involved_in valyl-tRNA aminoacylation	3	IBA,IEA,TAS	Drosophila_melanogaster(7227)	Process

Expression