RBP Type	N.A.
Diseases
Drug
Main interacting RNAs
Moonlighting functions
Localizations
BulkPerturb-seq

Ensembl ID	ENSMUSG00000037331	Gene ID	73158	Accession	-
Symbol	Larp1	Alias	Larp;mKIAA0731;1810024J12Rik;3110040D16Rik	Full Name	La ribonucleoprotein 1, translational regulator
Status	Confidence	Length	52971 bases	Strand	Plus strand
Position	11 : 57899890 - 57952860	RNA binding domain	La
Summary	Predicted to enable eukaryotic initiation factor 4E binding activity; nucleic acid binding activity; and ribosomal small subunit binding activity. Predicted to be involved in several processes, including TORC1 signaling; cellular response to rapamycin; and posttranscriptional regulation of gene expression. Predicted to act upstream of or within regulation of translation. Predicted to be located in cytoplasm. Predicted to be part of TORC1 complex and polysome. Predicted to be active in cytoplasmic stress granule and cytosol. Predicted to colocalize with polysomal ribosome. Is expressed in several structures, including branchial arch; cranial ganglion; epithelium; future spinal cord; and limb bud. Orthologous to human LARP1 (La ribonucleoprotein 1, translational regulator). [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSMUSP00000071421	La	PF05383	4.3e-20	1
ENSMUSP00000136673	La	PF05383	4.5e-20	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
Larp1-201	ENSMUST00000071487	6614	1072aa	ENSMUSP00000071421
Larp1-202	ENSMUST00000140500	747	No protein	-
Larp1-203	ENSMUST00000178636	6617	1072aa	ENSMUSP00000136673

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000037331	[{"sID": "ENSMUSG00000037331"	"sSP": "mus_musculus"	"sProtein": "ENSMUSP00000136673"	"sPercPos": 12.4067	"sPercID": 6.43657	"tID": "ENSMUSG00000068882"	"tSP": "mus_musculus"	"tGene": "Ssb"

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000037331

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000339	enables RNA cap binding	1	ISO	Mus_musculus(10090)	Function
GO:0000340	enables RNA 7-methylguanosine cap binding	1	ISO	Mus_musculus(10090)	Function
GO:0003723	enables RNA binding	1	IBA	Mus_musculus(10090)	Function
GO:0003730	enables mRNA 3-UTR binding	1	ISO	Mus_musculus(10090)	Function
GO:0005737	located_in cytoplasm	2	ISA,ISO	Mus_musculus(10090)	Component
GO:0005829	is_active_in cytosol	1	IBA	Mus_musculus(10090)	Component
GO:0005844	part_of polysome	1	ISO	Mus_musculus(10090)	Component
GO:0006413	involved_in translational initiation	1	ISO	Mus_musculus(10090)	Process
GO:0006417	acts_upstream_of_or_within regulation of translation	1	IEA	Mus_musculus(10090)	Process
GO:0008190	enables eukaryotic initiation factor 4E binding	1	ISO	Mus_musculus(10090)	Function
GO:0008283	involved_in cell population proliferation	1	ISO	Mus_musculus(10090)	Process
GO:0008494	enables translation activator activity	1	ISO	Mus_musculus(10090)	Function
GO:0010494	is_active_in cytoplasmic stress granule	2	IBA,ISO	Mus_musculus(10090)	Component
GO:0010608	involved_in post-transcriptional regulation of gene expression	1	ISO	Mus_musculus(10090)	Process
GO:0016239	involved_in positive regulation of macroautophagy	1	ISO	Mus_musculus(10090)	Process
GO:0017148	involved_in negative regulation of translation	1	ISO	Mus_musculus(10090)	Process
GO:0031369	enables translation initiation factor binding	1	ISO	Mus_musculus(10090)	Function
GO:0031929	involved_in TOR signaling	1	ISO	Mus_musculus(10090)	Process
GO:0031931	part_of TORC1 complex	1	ISO	Mus_musculus(10090)	Component
GO:0038202	involved_in TORC1 signaling	1	ISO	Mus_musculus(10090)	Process
GO:0042788	colocalizes_with polysomal ribosome	1	ISO	Mus_musculus(10090)	Component
GO:0043024	enables ribosomal small subunit binding	1	ISO	Mus_musculus(10090)	Function
GO:0045070	involved_in positive regulation of viral genome replication	1	ISO	Mus_musculus(10090)	Process
GO:0045727	involved_in positive regulation of translation	1	IBA	Mus_musculus(10090)	Process
GO:0045947	involved_in negative regulation of translational initiation	1	ISO	Mus_musculus(10090)	Process
GO:0045948	involved_in positive regulation of translational initiation	1	ISO	Mus_musculus(10090)	Process
GO:0048027	enables mRNA 5-UTR binding	1	ISO	Mus_musculus(10090)	Function
GO:0048255	involved_in mRNA stabilization	1	ISO	Mus_musculus(10090)	Process
GO:0072752	involved_in cellular response to rapamycin	1	ISO	Mus_musculus(10090)	Process
GO:1990928	involved_in response to amino acid starvation	1	ISO	Mus_musculus(10090)	Process