RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Description

Ensembl ID	ENSMUSG00000034839	Gene ID	67557	Accession	-
Symbol	Larp6	Alias	Achn;5430431G03Rik	Full Name	La ribonucleoprotein 6, translational regulator
Status	Confidence	Length	25813 bases	Strand	Plus strand
Position	9 : 60620272 - 60646084	RNA binding domain	SUZ-C , La
Summary	Predicted to enable RNA binding activity and myosin binding activity. Predicted to be involved in positive regulation of collagen biosynthetic process; positive regulation of mRNA binding activity; and positive regulation of translation. Predicted to act upstream of or within regulation of translation. Predicted to be located in cytoplasm. Predicted to be part of polysome. Predicted to be active in nucleus. Is expressed in brain; dorsal root ganglion; facial ganglion; and trigeminal ganglion. Orthologous to human LARP6 (La ribonucleoprotein 6, translational regulator). [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSMUSP00000040309	La	PF05383	6.4e-20	1
ENSMUSP00000040309	SUZ-C	PF12901	4.5e-08	2

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
Larp6-201	ENSMUST00000038407	2440	492aa	ENSMUSP00000040309

Gene Model

Click here to download ENSMUSG00000034839's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSMUSG00000034839's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000034839	[{"sID": "ENSMUSG00000034839"	"sSP": "mus_musculus"	"sProtein": "ENSMUSP00000040309"	"sPercPos": 31.0976	"sPercID": 15.8537	"tID": "ENSMUSG00000037331"	"tSP": "mus_musculus"	"tGene": "Larp1"

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000034839

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003676	enables nucleic acid binding	1	IEA	Mus_musculus(10090)	Function
GO:0003723	enables RNA binding	1	IEA	Mus_musculus(10090)	Function
GO:0003729	enables mRNA binding	1	IBA	Mus_musculus(10090)	Function
GO:0005515	enables protein binding	1	IPI	Mus_musculus(10090)	Function
GO:0005634	is_active_in nucleus	2	IBA,ISO	Mus_musculus(10090)	Component
GO:0005737	located_in cytoplasm	1	IEA	Mus_musculus(10090)	Component
GO:0005844	part_of polysome	2	IBA,ISO	Mus_musculus(10090)	Component
GO:0006396	involved_in RNA processing	1	IEA	Mus_musculus(10090)	Process
GO:0006417	acts_upstream_of_or_within regulation of translation	1	IEA	Mus_musculus(10090)	Process
GO:0017022	enables myosin binding	1	ISO	Mus_musculus(10090)	Function
GO:0032967	involved_in positive regulation of collagen biosynthetic process	1	ISO	Mus_musculus(10090)	Process
GO:0035613	enables RNA stem-loop binding	1	ISO	Mus_musculus(10090)	Function
GO:0045727	involved_in positive regulation of translation	1	ISO	Mus_musculus(10090)	Process
GO:0048027	enables mRNA 5-UTR binding	1	ISO	Mus_musculus(10090)	Function
GO:1902416	involved_in positive regulation of mRNA binding	1	ISO	Mus_musculus(10090)	Process
GO:1990825	enables sequence-specific mRNA binding	1	ISO	Mus_musculus(10090)	Function
GO:1990904	part_of ribonucleoprotein complex	1	ISO	Mus_musculus(10090)	Component

Expression