RBPWorld - a comprehensive database of RNA Binding Proteins

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Description

Ensembl ID	ENSMUSG00000028792	Gene ID	11637	Accession	-
Symbol	Ak2	Alias	Ak-2;D4Ertd220e	Full Name	adenylate kinase 2
Status	Confidence	Length	18306 bases	Strand	Plus strand
Position	4 : 128887017 - 128905322	RNA binding domain	ADK_lid
Summary	Predicted to enable adenylate kinase activity. Predicted to contribute to nucleobase-containing compound kinase activity. Predicted to be involved in ATP metabolic process and purine nucleotide metabolic process. Predicted to act upstream of or within phosphorylation. Located in sperm mitochondrial sheath. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Human ortholog(s) of this gene implicated in reticular dysgenesis. Orthologous to human AK2 (adenylate kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSMUSP00000099664	ADK_lid	PF05191	9.2e-17	1
ENSMUSP00000030583	ADK_lid	PF05191	9.5e-17	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
Ak2-203	ENSMUST00000141982	356	No protein	-
Ak2-201	ENSMUST00000030583	986	239aa	ENSMUSP00000030583
Ak2-202	ENSMUST00000102604	1781	232aa	ENSMUSP00000099664
Ak2-204	ENSMUST00000152762	749	72aa	ENSMUSP00000122284

Gene Model

Click here to download ENSMUSG00000028792's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSMUSG00000028792's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000028792	[{"sID": "ENSMUSG00000028792"	"sSP": "mus_musculus"	"sProtein": "ENSMUSP00000030583"	"sPercPos": 42.2594	"sPercID": 19.6653	"tID": "ENSMUSG00000091415"	"tSP": "mus_musculus"	"tGene": "NA"

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000028792

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000166	enables nucleotide binding	1	IEA	Mus_musculus(10090)	Function
GO:0004017	enables adenylate kinase activity	2	IBA,ISO	Mus_musculus(10090)	Function
GO:0005524	enables ATP binding	1	IEA	Mus_musculus(10090)	Function
GO:0005737	is_active_in cytoplasm	1	IBA	Mus_musculus(10090)	Component
GO:0005739	located_in mitochondrion	2	HDA,IBA	Mus_musculus(10090)	Component
GO:0005743	located_in mitochondrial inner membrane	1	HDA	Mus_musculus(10090)	Component
GO:0006139	involved_in nucleobase-containing compound metabolic process	1	IEA	Mus_musculus(10090)	Process
GO:0006172	involved_in ADP biosynthetic process	1	ISO	Mus_musculus(10090)	Process
GO:0016301	enables kinase activity	1	IEA	Mus_musculus(10090)	Function
GO:0016310	acts_upstream_of_or_within phosphorylation	1	IEA	Mus_musculus(10090)	Process
GO:0016740	enables transferase activity	1	IEA	Mus_musculus(10090)	Function
GO:0016776	enables phosphotransferase activity, phosphate group as acceptor	1	IEA	Mus_musculus(10090)	Function
GO:0019205	contributes_to nucleobase-containing compound kinase activity	1	ISO	Mus_musculus(10090)	Function
GO:0036126	located_in sperm flagellum	1	IDA	Mus_musculus(10090)	Component
GO:0046033	involved_in AMP metabolic process	1	ISO	Mus_musculus(10090)	Process
GO:0046060	involved_in dATP metabolic process	1	ISO	Mus_musculus(10090)	Process
GO:0097226	located_in sperm mitochondrial sheath	1	IDA	Mus_musculus(10090)	Component

Expression