RBP Type	N.A.
Diseases
Drug
Main interacting RNAs
Moonlighting functions
Localizations
BulkPerturb-seq

Ensembl ID	ENSMUSG00000028527	Gene ID	11639	Accession	-
Symbol	Ak4	Alias	Ak3;AK4;Ak-3;Ak-4;Ak3l1;D4Ertd274e	Full Name	adenylate kinase 4
Status	Confidence	Length	47719 bases	Strand	Plus strand
Position	4 : 101276474 - 101324192	RNA binding domain	ADK_lid
Summary	Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in several processes, including nucleoside phosphate metabolic process; regulation of ATP biosynthetic process; and regulation of oxidative phosphorylation. Predicted to act upstream of or within phosphorylation. Located in mitochondrial matrix. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human AK4 (adenylate kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSMUSP00000115454	ADK_lid	PF05191	6.5e-16	1
ENSMUSP00000099841	ADK_lid	PF05191	3.5e-15	1
ENSMUSP00000102558	ADK_lid	PF05191	3.5e-15	1
ENSMUSP00000102559	ADK_lid	PF05191	3.5e-15	1
ENSMUSP00000121112	ADK_lid	PF05191	7.7e-07	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
Ak4-201	ENSMUST00000102780	4186	223aa	ENSMUSP00000099841
Ak4-203	ENSMUST00000106946	4360	223aa	ENSMUSP00000102559
Ak4-202	ENSMUST00000106945	4175	223aa	ENSMUSP00000102558
Ak4-204	ENSMUST00000131397	462	115aa	ENSMUSP00000115456
Ak4-205	ENSMUST00000133055	458	123aa	ENSMUSP00000115454
Ak4-206	ENSMUST00000151561	791	No protein	-
Ak4-207	ENSMUST00000155749	537	141aa	ENSMUSP00000121112

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000028527	[{"sID": "ENSMUSG00000028527"	"sSP": "mus_musculus"	"sProtein": "ENSMUSP00000102559"	"sPercPos": 40.8072	"sPercID": 21.5247	"tID": "ENSMUSG00000091415"	"tSP": "mus_musculus"	"tGene": "NA"

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000028527

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000166	enables nucleotide binding	1	IEA	Mus_musculus(10090)	Function
GO:0002082	involved_in regulation of oxidative phosphorylation	1	ISO	Mus_musculus(10090)	Process
GO:0004017	enables adenylate kinase activity	1	IEA	Mus_musculus(10090)	Function
GO:0004550	enables nucleoside diphosphate kinase activity	2	IBA,ISO	Mus_musculus(10090)	Function
GO:0005524	enables ATP binding	1	IEA	Mus_musculus(10090)	Function
GO:0005525	enables GTP binding	1	IEA	Mus_musculus(10090)	Function
GO:0005737	is_active_in cytoplasm	1	IBA	Mus_musculus(10090)	Component
GO:0005739	located_in mitochondrion	2	HDA,ISO	Mus_musculus(10090)	Component
GO:0005759	is_active_in mitochondrial matrix	2	IBA,IDA	Mus_musculus(10090)	Component
GO:0006139	involved_in nucleobase-containing compound metabolic process	1	IEA	Mus_musculus(10090)	Process
GO:0009142	involved_in nucleoside triphosphate biosynthetic process	1	IBA	Mus_musculus(10090)	Process
GO:0009188	involved_in ribonucleoside diphosphate biosynthetic process	1	ISO	Mus_musculus(10090)	Process
GO:0016301	enables kinase activity	1	IEA	Mus_musculus(10090)	Function
GO:0016310	acts_upstream_of_or_within phosphorylation	1	IEA	Mus_musculus(10090)	Process
GO:0016740	enables transferase activity	1	IEA	Mus_musculus(10090)	Function
GO:0016776	enables phosphotransferase activity, phosphate group as acceptor	1	IEA	Mus_musculus(10090)	Function
GO:0019205	enables nucleobase-containing compound kinase activity	1	IEA	Mus_musculus(10090)	Function
GO:0046033	involved_in AMP metabolic process	2	IBA,ISO	Mus_musculus(10090)	Process
GO:0046034	involved_in ATP metabolic process	1	ISO	Mus_musculus(10090)	Process
GO:0046039	involved_in GTP metabolic process	1	ISO	Mus_musculus(10090)	Process
GO:0046899	enables nucleoside triphosphate adenylate kinase activity	1	IEA	Mus_musculus(10090)	Function
GO:0071456	acts_upstream_of cellular response to hypoxia	1	ISO	Mus_musculus(10090)	Process