RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Description

Ensembl ID	ENSMUSG00000023025	Gene ID	207214	Accession	-
Symbol	Larp4	Alias	DXErtd793;DXErtd793e	Full Name	La ribonucleoprotein 4
Status	Confidence	Length	46294 bases	Strand	Plus strand
Position	15 : 99867946 - 99914239	RNA binding domain	La
Summary	Predicted to enable mRNA 3'-UTR binding activity and poly(A) binding activity. Predicted to be involved in cytoskeleton organization; positive regulation of translation; and regulation of cell morphogenesis. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of cytosolic small ribosomal subunit and polysome. Predicted to be active in cytoplasmic stress granule and cytosol. Orthologous to human LARP4 (La ribonucleoprotein 4). [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSMUSP00000155601	La	PF05383	3.8e-17	1
ENSMUSP00000155661	La	PF05383	4.3e-17	1
ENSMUSP00000086964	La	PF05383	4.9e-17	1
ENSMUSP00000097780	La	PF05383	4.9e-17	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
Larp4-201	ENSMUST00000057632	4196	718aa	ENSMUSP00000086964
Larp4-202	ENSMUST00000100206	6530	719aa	ENSMUSP00000097780
Larp4-207	ENSMUST00000230956	2192	610aa	ENSMUSP00000155601
Larp4-204	ENSMUST00000229553	1420	No protein	-
Larp4-205	ENSMUST00000229891	4207	No protein	-
Larp4-209	ENSMUST00000231160	3935	660aa	ENSMUSP00000155661
Larp4-206	ENSMUST00000230521	1499	107aa	ENSMUSP00000155529
Larp4-203	ENSMUST00000229426	606	No protein	-
Larp4-208	ENSMUST00000231128	643	No protein	-

Gene Model

Click here to download ENSMUSG00000023025's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSMUSG00000023025's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000023025	[{"sID": "ENSMUSG00000023025"	"sSP": "mus_musculus"	"sProtein": "ENSMUSP00000097780"	"sPercPos": 32.4061	"sPercID": 17.9416	"tID": "ENSMUSG00000037331"	"tSP": "mus_musculus"	"tGene": "Larp1"

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000023025

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003676	enables nucleic acid binding	1	IEA	Mus_musculus(10090)	Function
GO:0003723	enables RNA binding	1	IEA	Mus_musculus(10090)	Function
GO:0003730	enables mRNA 3-UTR binding	2	IBA,ISO	Mus_musculus(10090)	Function
GO:0005737	located_in cytoplasm	1	IEA	Mus_musculus(10090)	Component
GO:0005829	is_active_in cytosol	2	IBA,ISO	Mus_musculus(10090)	Component
GO:0005844	part_of polysome	1	ISO	Mus_musculus(10090)	Component
GO:0006412	acts_upstream_of_or_within translation	1	IEA	Mus_musculus(10090)	Process
GO:0007010	involved_in cytoskeleton organization	1	ISO	Mus_musculus(10090)	Process
GO:0008143	enables poly(A) binding	1	ISO	Mus_musculus(10090)	Function
GO:0010494	is_active_in cytoplasmic stress granule	2	IBA,ISO	Mus_musculus(10090)	Component
GO:0010608	involved_in post-transcriptional regulation of gene expression	1	ISO	Mus_musculus(10090)	Process
GO:0022604	involved_in regulation of cell morphogenesis	1	ISO	Mus_musculus(10090)	Process
GO:0022627	part_of cytosolic small ribosomal subunit	1	ISO	Mus_musculus(10090)	Component
GO:0045727	involved_in positive regulation of translation	2	IBA,ISO	Mus_musculus(10090)	Process

Expression