RBPWorld - a comprehensive database of RNA Binding Proteins

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Description

Ensembl ID	ENSMUSG00000020781	Gene ID	76265	Accession	-
Symbol	Tsen54	Alias	0610034P02Rik	Full Name	tRNA splicing endonuclease subunit 54
Status	Confidence	Length	8371 bases	Strand	Plus strand
Position	11 : 115705550 - 115713920	RNA binding domain	tRNA_int_end_N2
Summary	Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to act upstream of or within mRNA processing and tRNA processing. Predicted to be located in nucleus. Predicted to be part of tRNA-intron endonuclease complex. Is expressed in cerebellum; retina inner nuclear layer; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2A; pontocerebellar hypoplasia type 4; and pontocerebellar hypoplasia type 5. Orthologous to human TSEN54 (tRNA splicing endonuclease subunit 54). [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSMUSP00000102090	tRNA_int_end_N2	PF12928	3.2e-18	1
ENSMUSP00000021134	tRNA_int_end_N2	PF12928	3.6e-18	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
Tsen54-201	ENSMUST00000021134	1979	525aa	ENSMUSP00000021134
Tsen54-202	ENSMUST00000106481	1862	486aa	ENSMUSP00000102090
Tsen54-204	ENSMUST00000129765	522	No protein	-
Tsen54-206	ENSMUST00000141748	858	No protein	-
Tsen54-203	ENSMUST00000128266	803	No protein	-
Tsen54-205	ENSMUST00000136343	825	275aa	ENSMUSP00000120506
Tsen54-207	ENSMUST00000154304	963	153aa	ENSMUSP00000116955
Tsen54-208	ENSMUST00000157061	494	165aa	ENSMUSP00000118342

Gene Model

Click here to download ENSMUSG00000020781's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSMUSG00000020781's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000020781

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000020781

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000214	part_of tRNA-intron endonuclease complex	1	IBA	Mus_musculus(10090)	Component
GO:0000379	involved_in tRNA-type intron splice site recognition and cleavage	1	IBA	Mus_musculus(10090)	Process
GO:0005634	located_in nucleus	1	IEA	Mus_musculus(10090)	Component
GO:0006388	involved_in tRNA splicing, via endonucleolytic cleavage and ligation	1	ISO	Mus_musculus(10090)	Process
GO:0006397	acts_upstream_of_or_within mRNA processing	1	IEA	Mus_musculus(10090)	Process
GO:0008033	acts_upstream_of_or_within tRNA processing	1	IEA	Mus_musculus(10090)	Process

Expression