RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Description

Ensembl ID	ENSMUSG00000020003	Gene ID	18634	Accession	-
Symbol	Pex7	Alias	MmPEX7	Full Name	peroxisomal biogenesis factor 7
Status	Confidence	Length	53790 bases	Strand	Minus strand
Position	10 : 19729646 - 19783435	RNA binding domain	eIF2A
Summary	Predicted to enable enzyme binding activity; peroxisome matrix targeting signal-2 binding activity; and protein homodimerization activity. Acts upstream of or within several processes, including endochondral ossification; fatty acid beta-oxidation; and protein import into peroxisome matrix. Located in cytosol. Is expressed in 2-cell stage embryo and 4-cell stage embryo. Used to study rhizomelic chondrodysplasia punctata type 1. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and rhizomelic chondrodysplasia punctata type 1. Orthologous to human PEX7 (peroxisomal biogenesis factor 7). [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSMUSP00000020182	eIF2A	PF08662	0.00014	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
Pex7-201	ENSMUST00000020182	8099	318aa	ENSMUSP00000020182
Pex7-202	ENSMUST00000125942	587	No protein	-
Pex7-203	ENSMUST00000166511	1047	292aa	ENSMUSP00000132996
Pex7-204	ENSMUST00000214951	4114	No protein	-

Gene Model

Click here to download ENSMUSG00000020003's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSMUSG00000020003's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000020003	[{"sID": "ENSMUSG00000020003"	"sSP": "mus_musculus"	"sProtein": "ENSMUSP00000020182"	"sPercPos": 25.1572	"sPercID": 12.2642	"tID": "ENSMUSG00000021694"	"tSP": "mus_musculus"	"tGene": "NA"

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000020003

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001764	acts_upstream_of_or_within neuron migration	1	IMP	Mus_musculus(10090)	Process
GO:0001958	acts_upstream_of_or_within endochondral ossification	1	IMP	Mus_musculus(10090)	Process
GO:0005053	enables peroxisome matrix targeting signal-2 binding	2	IBA,ISO	Mus_musculus(10090)	Function
GO:0005737	located_in cytoplasm	1	IEA	Mus_musculus(10090)	Component
GO:0005777	located_in peroxisome	1	ISO	Mus_musculus(10090)	Component
GO:0005782	is_active_in peroxisomal matrix	2	IBA,ISO	Mus_musculus(10090)	Component
GO:0005829	is_active_in cytosol	3	IBA,IDA,ISO	Mus_musculus(10090)	Component
GO:0006625	acts_upstream_of_or_within protein targeting to peroxisome	1	IMP	Mus_musculus(10090)	Process
GO:0006635	acts_upstream_of_or_within fatty acid beta-oxidation	1	IMP	Mus_musculus(10090)	Process
GO:0007031	involved_in peroxisome organization	1	ISO	Mus_musculus(10090)	Process
GO:0008611	involved_in ether lipid biosynthetic process	1	ISO	Mus_musculus(10090)	Process
GO:0015031	acts_upstream_of_or_within protein transport	1	IEA	Mus_musculus(10090)	Process
GO:0016558	involved_in protein import into peroxisome matrix	4	IBA,IMP,ISO	Mus_musculus(10090)	Process
GO:0019899	enables enzyme binding	1	ISO	Mus_musculus(10090)	Function
GO:0042803	enables protein homodimerization activity	1	ISO	Mus_musculus(10090)	Function

Expression