RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Description

Ensembl ID	ENSMUSG00000015748	Gene ID	70767	Accession	-
Symbol	Prpf3	Alias	3632413F13Rik	Full Name	pre-mRNA processing factor 3
Status	Confidence	Length	25762 bases	Strand	Minus strand
Position	3 : 95737436 - 95763197	RNA binding domain	PWI , PRP3
Summary	Predicted to enable identical protein binding activity. Predicted to be involved in spliceosomal tri-snRNP complex assembly. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in Cajal body; cytosol; and nuclear speck. Predicted to be part of U2-type precatalytic spliceosome and U4/U6 x U5 tri-snRNP complex. Is expressed in central nervous system; genitourinary system; gut gland; heart; and sensory organ. Used to study retinitis pigmentosa 18. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 18. Orthologous to human PRPF3 (pre-mRNA processing factor 3). [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSMUSP00000015892	PRP3	PF08572	9.2e-75	1
ENSMUSP00000015892	PWI	PF01480	2.2e-13	2
ENSMUSP00000124950	PRP3	PF08572	9.2e-75	1
ENSMUSP00000124950	PWI	PF01480	2.2e-13	2
ENSMUSP00000124302	PWI	PF01480	1.1e-14	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
Prpf3-201	ENSMUST00000015892	2933	683aa	ENSMUSP00000015892
Prpf3-202	ENSMUST00000159901	575	114aa	ENSMUSP00000124444
Prpf3-204	ENSMUST00000160155	2548	No protein	-
Prpf3-209	ENSMUST00000163059	592	No protein	-
Prpf3-207	ENSMUST00000161476	2732	683aa	ENSMUSP00000124950
Prpf3-208	ENSMUST00000161482	554	No protein	-
Prpf3-206	ENSMUST00000161420	1800	No protein	-
Prpf3-203	ENSMUST00000160109	800	101aa	ENSMUSP00000124302
Prpf3-205	ENSMUST00000161073	613	No protein	-

Gene Model

Click here to download ENSMUSG00000015748's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSMUSG00000015748's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000015748

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSMUSG00000015748

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000244	involved_in spliceosomal tri-snRNP complex assembly	1	ISO	Mus_musculus(10090)	Process
GO:0000398	involved_in mRNA splicing, via spliceosome	2	IBA,ISO	Mus_musculus(10090)	Process
GO:0005634	located_in nucleus	1	ISO	Mus_musculus(10090)	Component
GO:0005654	located_in nucleoplasm	1	ISO	Mus_musculus(10090)	Component
GO:0005681	part_of spliceosomal complex	1	IEA	Mus_musculus(10090)	Component
GO:0005829	located_in cytosol	1	ISO	Mus_musculus(10090)	Component
GO:0006397	acts_upstream_of_or_within mRNA processing	2	IEA	Mus_musculus(10090)	Process
GO:0008380	acts_upstream_of_or_within RNA splicing	1	IEA	Mus_musculus(10090)	Process
GO:0015030	located_in Cajal body	1	ISO	Mus_musculus(10090)	Component
GO:0016607	located_in nuclear speck	1	ISO	Mus_musculus(10090)	Component
GO:0032991	part_of protein-containing complex	1	ISO	Mus_musculus(10090)	Component
GO:0042802	enables identical protein binding	1	ISO	Mus_musculus(10090)	Function
GO:0046540	part_of U4/U6 x U5 tri-snRNP complex	2	IBA,ISO	Mus_musculus(10090)	Component
GO:0071005	part_of U2-type precatalytic spliceosome	1	ISO	Mus_musculus(10090)	Component

Expression