RBP Type	Non-canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Stress granucle
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000278637	Gene ID	8359	Accession	4781
Symbol	H4C1	Alias	H4C2;H4C3;H4C4;H4C5;H4C6;H4C8;H4C9;H4FA;H4-16;H4C11;H4C12;H4C13;H4C14;H4C15;H4C16;HIST1H4A	Full Name	H4 clustered histone 1
Status	Confidence	Length	402 bases	Strand	Plus strand
Position	6 : 26021649 - 26022050	RNA binding domain	N.A.
Summary	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000278637	homo_sapiens	ENSP00000484789	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000479794	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000443017	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000481486	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000462355	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000347168	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000479461	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000366974	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000480960	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000367034	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000462667	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000244537	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000366956	100	100	homo_sapiens	ENSP00000479106	100	100
ENSG00000278637	homo_sapiens	ENSP00000477870	84.6939	84.6939	homo_sapiens	ENSP00000479106	80.5825	80.5825

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	nomascus_leucogenys	ENSNLEP00000046925	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	pan_paniscus	ENSPPAP00000000659	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	loxodonta_africana	ENSLAFP00000016306	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	bos_indicus_hybrid	ENSBIXP00005006023	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	panthera_pardus	ENSPPRP00000024153	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	physeter_catodon	ENSPCTP00005007214	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	mus_musculus	ENSMUSP00000100546	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	phocoena_sinus	ENSPSNP00000007166	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	phocoena_sinus	ENSPSNP00000007175	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	rattus_norvegicus	ENSRNOP00000087795	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	microtus_ochrogaster	ENSMOCP00000001419	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	bos_taurus	ENSBTAP00000062765	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	cervus_hanglu_yarkandensis	ENSCHYP00000022532	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	propithecus_coquereli	ENSPCOP00000002858	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	98.0583	drosophila_melanogaster	FBpp0091114	100	98.0583
ENSG00000278637	homo_sapiens	ENSP00000479106	100	98.0583	drosophila_melanogaster	FBpp0091122	100	98.0583
ENSG00000278637	homo_sapiens	ENSP00000479106	100	98.0583	drosophila_melanogaster	FBpp0091124	100	98.0583
ENSG00000278637	homo_sapiens	ENSP00000479106	100	98.0583	drosophila_melanogaster	FBpp0091126	100	98.0583
ENSG00000278637	homo_sapiens	ENSP00000479106	99.0291	97.0874	callorhinchus_milii	ENSCMIP00000003320	99.0291	97.0874
ENSG00000278637	homo_sapiens	ENSP00000479106	99.0291	97.0874	callorhinchus_milii	ENSCMIP00000000320	99.0291	97.0874
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	latimeria_chalumnae	ENSLACP00000004892	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	xiphophorus_maculatus	ENSXMAP00000024421	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	100	99.0291	ciona_savignyi	ENSCSAVP00000017130	44.5887	44.1558
ENSG00000278637	homo_sapiens	ENSP00000479106	100	99.0291	ciona_savignyi	ENSCSAVP00000013535	45.7778	45.3333
ENSG00000278637	homo_sapiens	ENSP00000479106	100	99.0291	ciona_savignyi	ENSCSAVP00000000940	44.5887	44.1558
ENSG00000278637	homo_sapiens	ENSP00000479106	100	99.0291	ciona_savignyi	ENSCSAVP00000017227	44.7826	44.3478
ENSG00000278637	homo_sapiens	ENSP00000479106	97.0874	92.233	saccharomyces_cerevisiae	YBR009C	97.0874	92.233
ENSG00000278637	homo_sapiens	ENSP00000479106	97.0874	92.233	saccharomyces_cerevisiae	YNL030W	97.0874	92.233
ENSG00000278637	homo_sapiens	ENSP00000479106	100	100	cyprinodon_variegatus	ENSCVAP00000011029	100	100
ENSG00000278637	homo_sapiens	ENSP00000479106	90.2913	90.2913	paramormyrops_kingsleyae	ENSPKIP00000038554	100	100

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000781	located_in chromosome, telomeric region	1	HDA	Homo_sapiens(9606)	Component
GO:0000786	part_of nucleosome	3	IDA,IPI,TAS	Homo_sapiens(9606)	Component
GO:0003677	enables DNA binding	2	IBA,TAS	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005576	located_in extracellular region	1	TAS	Homo_sapiens(9606)	Component
GO:0005634	located_in nucleus	2	HDA,IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0006334	involved_in nucleosome assembly	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0030527	enables structural constituent of chromatin	1	IDA	Homo_sapiens(9606)	Function
GO:0032200	involved_in telomere organization	1	TAS	Homo_sapiens(9606)	Process
GO:0032991	part_of protein-containing complex	1	IDA	Homo_sapiens(9606)	Component
GO:0043505	part_of CENP-A containing nucleosome	1	IPI	Homo_sapiens(9606)	Component
GO:0045653	involved_in negative regulation of megakaryocyte differentiation	1	IDA	Homo_sapiens(9606)	Process
GO:0046982	enables protein heterodimerization activity	1	IEA	Homo_sapiens(9606)	Function
GO:0061644	involved_in protein localization to CENP-A containing chromatin	1	NAS	Homo_sapiens(9606)	Process
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component