RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000269190	Gene ID	115290	Accession	18754
Symbol	FBXO17	Alias	FBG4;FBX26;Fbx17;FBXO26	Full Name	F-box protein 17
Status	Confidence	Length	34342 bases	Strand	Minus strand
Position	19 : 38941401 - 38975742	RNA binding domain	N.A.
Summary	This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
FBXO17-201	ENST00000292852	2218	278aa	ENSP00000292852
FBXO17-205	ENST00000599418	2222	No protein	-
FBXO17-202	ENST00000595329	1299	278aa	ENSP00000470361
FBXO17-204	ENST00000597696	932	No protein	-
FBXO17-203	ENST00000596025	935	177aa	ENSP00000470101
FBXO17-206	ENST00000599598	510	94aa	ENSP00000470390
FBXO17-207	ENST00000601394	2366	109aa	ENSP00000469852

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
23902	Obesity	1.6380000E-005	-
24692	Muscle, Skeletal	6.0290000E-005	-
36698	Platelet Function Tests	2.9618000E-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	2	IDA,IPI	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0006516	involved_in glycoprotein catabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0019005	part_of SCF ubiquitin ligase complex	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0030433	involved_in ubiquitin-dependent ERAD pathway	1	IBA	Homo_sapiens(9606)	Process
GO:0031146	involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0061630	contributes_to ubiquitin protein ligase activity	1	IBA	Homo_sapiens(9606)	Function