RBP Type
Non-canonical_RBPs
Diseases
N.A.
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
TF
Localizations
N.A.
BulkPerturb-seq
Ensembl ID ENSG00000257315 Gene ID
100381270
Accession
33273
Symbol
ZBED6
Alias
MGR
Full Name
zinc finger BED-type containing 6
Status
Confidence
Length
58502 bases
Strand
Plus strand
Position
1 : 203795623 - 203854124
RNA binding domain
N.A.
Summary
The protein encoded by this transposon-derived intronless gene is a transcriptional repressor that binds to the consensus sequence 5'-GCTCGC-3'. The encoded protein has been shown to repress IGF2 transcription. This gene is located within the first intron of the ZC3H11A gene. [provided by RefSeq, Jul 2016]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
ZBED6-201
ENST00000550078
11697
979aa
ENSP00000447879
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
81580 Breast Neoplasms 9E-9 25038754
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000122 involved_in negative regulation of transcription by RNA polymerase II 1 ISS Homo_sapiens(9606) Process GO:0000785 part_of chromatin 1 ISA Homo_sapiens(9606) Component GO:0000976 enables transcription cis-regulatory region binding 1 ISS Homo_sapiens(9606) Function GO:0000981 enables DNA-binding transcription factor activity, RNA polymerase II-specific 1 ISA Homo_sapiens(9606) Function GO:0001227 enables DNA-binding transcription repressor activity, RNA polymerase II-specific 1 ISS Homo_sapiens(9606) Function GO:0001835 involved_in blastocyst hatching 1 IEA Homo_sapiens(9606) Process GO:0005634 is_active_in nucleus 3 IBA,IDA,ISS Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 1 IDA Homo_sapiens(9606) Component GO:0005730 located_in nucleolus 1 ISS Homo_sapiens(9606) Component GO:0005737 located_in cytoplasm 2 IDA,ISS Homo_sapiens(9606) Component GO:0006357 involved_in regulation of transcription by RNA polymerase II 1 IBA Homo_sapiens(9606) Process GO:0034451 located_in centriolar satellite 1 IDA Homo_sapiens(9606) Component GO:0045892 involved_in negative regulation of DNA-templated transcription 1 ISS Homo_sapiens(9606) Process GO:0046872 enables metal ion binding 1 IEA Homo_sapiens(9606) Function GO:0046983 enables protein dimerization activity 1 IEA Homo_sapiens(9606) Function GO:0051148 involved_in negative regulation of muscle cell differentiation 1 ISS Homo_sapiens(9606) Process GO:0061178 involved_in regulation of insulin secretion involved in cellular response to glucose stimulus 1 IEA Homo_sapiens(9606) Process
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.