RBP Type	Canonical_RBPs
Diseases	FlavivirusesSARS-COV-2SINVDengueZika
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Stress granucleP-body
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000247315	Gene ID	85364	Accession	16230
Symbol	ZCCHC3	Alias	C20orf99	Full Name	zinc finger CCHC-type containing 3
Status	Confidence	Length	2752 bases	Strand	Plus strand
Position	20 : 297570 - 300321	RNA binding domain	zf-CCHC
Summary	Enables double-stranded DNA binding activity. Involved in several processes, including cellular response to exogenous dsRNA; detection of virus; and positive regulation of RIG-I signaling pathway. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000484056	zf-CCHC	PF00098	2.4e-05	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
29309035	Dissection of affinity captured LINE-1 macromolecular complexes.	S Martin Taylor	2018-01-08	eLife
37405998	ZCCHC3 is a stress granule zinc knuckle protein that strongly suppresses LINE-1 retrotransposition.	L John Goodier	2023-07-01	PLoS genetics
30135424	ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response.	Huan Lian	2018-08-22	Nature communications
36274734	The Zinc-Finger protein ZCCHC3 inhibits LINE-1 retrotransposition.	Zixiong Zhang	2022-01-01	Frontiers in microbiology

Name	Transcript ID	bp	Protein	Translation ID
ZCCHC3-201	ENST00000500893	2752	403aa	ENSP00000484056

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
13069	Bipolar Disorder	6.19E-5	19488044
19428	Pulse Wave Analysis	6.049e-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000247315

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000247315	homo_sapiens	ENSP00000484056	93.3002	93.3002	nomascus_leucogenys	ENSNLEP00000025485	96.9072	96.9072
ENSG00000247315	homo_sapiens	ENSP00000484056	64.5161	64.5161	pan_paniscus	ENSPPAP00000002309	98.1132	98.1132
ENSG00000247315	homo_sapiens	ENSP00000484056	98.7593	98.5112	pongo_abelii	ENSPPYP00000040392	97.549	97.3039
ENSG00000247315	homo_sapiens	ENSP00000484056	99.7519	99.7519	pan_troglodytes	ENSPTRP00000080723	99.2593	99.2593
ENSG00000247315	homo_sapiens	ENSP00000484056	81.3896	81.3896	gorilla_gorilla	ENSGGOP00000032880	100	100
ENSG00000247315	homo_sapiens	ENSP00000484056	92.3077	91.3151	dasypus_novemcinctus	ENSDNOP00000030426	92.0792	91.0891
ENSG00000247315	homo_sapiens	ENSP00000484056	80.1489	77.9156	echinops_telfairi	ENSETEP00000008427	88.4931	86.0274
ENSG00000247315	homo_sapiens	ENSP00000484056	99.0074	98.263	cercocebus_atys	ENSCATP00000007422	99.2537	98.5075
ENSG00000247315	homo_sapiens	ENSP00000484056	89.8263	87.5931	macaca_fascicularis	ENSMFAP00000026710	86.6029	84.4498
ENSG00000247315	homo_sapiens	ENSP00000484056	98.7593	98.263	macaca_mulatta	ENSMMUP00000057104	99.005	98.5075
ENSG00000247315	homo_sapiens	ENSP00000484056	98.7593	98.263	macaca_nemestrina	ENSMNEP00000000130	99.005	98.5075
ENSG00000247315	homo_sapiens	ENSP00000484056	99.0074	98.5112	papio_anubis	ENSPANP00000016902	99.2537	98.7562
ENSG00000247315	homo_sapiens	ENSP00000484056	93.5484	93.0521	tursiops_truncatus	ENSTTRP00000008040	93.3168	92.8218
ENSG00000247315	homo_sapiens	ENSP00000484056	89.8263	87.3449	mus_spretus	MGP_SPRETEiJ_P0057374	90.5	88
ENSG00000247315	homo_sapiens	ENSP00000484056	95.2854	94.7891	equus_asinus	ENSEASP00005046786	72.4528	72.0755
ENSG00000247315	homo_sapiens	ENSP00000484056	94.2928	93.5484	capra_hircus	ENSCHIP00000005894	94.0594	93.3168
ENSG00000247315	homo_sapiens	ENSP00000484056	64.7643	64.0199	loxodonta_africana	ENSLAFP00000026790	95.9559	94.8529
ENSG00000247315	homo_sapiens	ENSP00000484056	93.5484	93.3002	panthera_leo	ENSPLOP00000014735	95.202	94.9495
ENSG00000247315	homo_sapiens	ENSP00000484056	94.2928	93.3002	bos_indicus_hybrid	ENSBIXP00005042183	94.0594	93.0693
ENSG00000247315	homo_sapiens	ENSP00000484056	94.7891	94.2928	equus_caballus	ENSECAP00000000688	94.7891	94.2928
ENSG00000247315	homo_sapiens	ENSP00000484056	95.2854	95.0372	canis_lupus_familiaris	ENSCAFP00845023598	72.5898	72.4008
ENSG00000247315	homo_sapiens	ENSP00000484056	95.2854	95.0372	panthera_pardus	ENSPPRP00000024534	95.0495	94.802
ENSG00000247315	homo_sapiens	ENSP00000484056	93.5484	93.0521	balaenoptera_musculus	ENSBMSP00010017394	93.3168	92.8218
ENSG00000247315	homo_sapiens	ENSP00000484056	87.5931	84.8635	cavia_porcellus	ENSCPOP00000019354	89.5939	86.802
ENSG00000247315	homo_sapiens	ENSP00000484056	87.3449	86.1042	ursus_americanus	ENSUAMP00000030482	88.2206	86.9674
ENSG00000247315	homo_sapiens	ENSP00000484056	59.0571	47.6427	monodelphis_domestica	ENSMODP00000054952	61.9792	50
ENSG00000247315	homo_sapiens	ENSP00000484056	94.0447	93.0521	bison_bison_bison	ENSBBBP00000017459	93.8119	92.8218
ENSG00000247315	homo_sapiens	ENSP00000484056	93.0521	92.5558	monodon_monoceros	ENSMMNP00015000164	93.5162	93.0175
ENSG00000247315	homo_sapiens	ENSP00000484056	93.5484	93.0521	sus_scrofa	ENSSSCP00000076317	93.7811	93.2836
ENSG00000247315	homo_sapiens	ENSP00000484056	94.5409	94.2928	microcebus_murinus	ENSMICP00000032369	95.0125	94.7631
ENSG00000247315	homo_sapiens	ENSP00000484056	90.8189	89.8263	octodon_degus	ENSODEP00000014505	91.0448	90.0498
ENSG00000247315	homo_sapiens	ENSP00000484056	91.3151	88.3375	jaculus_jaculus	ENSJJAP00000019403	90.4177	87.4693
ENSG00000247315	homo_sapiens	ENSP00000484056	94.5409	93.7965	ovis_aries_rambouillet	ENSOARP00020004722	94.3069	93.5644
ENSG00000247315	homo_sapiens	ENSP00000484056	93.5484	91.3151	ochotona_princeps	ENSOPRP00000004661	91.9512	89.7561
ENSG00000247315	homo_sapiens	ENSP00000484056	92.5558	92.0596	delphinapterus_leucas	ENSDLEP00000018308	93.0175	92.5187
ENSG00000247315	homo_sapiens	ENSP00000484056	93.7965	93.3002	physeter_catodon	ENSPCTP00005021763	93.5644	93.0693
ENSG00000247315	homo_sapiens	ENSP00000484056	89.8263	87.0968	mus_caroli	MGP_CAROLIEiJ_P0055231	90.5	87.75
ENSG00000247315	homo_sapiens	ENSP00000484056	89.5782	87.0968	mus_musculus	ENSMUSP00000096813	90.25	87.75
ENSG00000247315	homo_sapiens	ENSP00000484056	26.3027	25.3102	mustela_putorius_furo	ENSMPUP00000017811	89.0756	85.7143
ENSG00000247315	homo_sapiens	ENSP00000484056	96.0298	95.0372	aotus_nancymaae	ENSANAP00000001516	96.75	95.75
ENSG00000247315	homo_sapiens	ENSP00000484056	59.0571	58.8089	vicugna_pacos	ENSVPAP00000010491	96.748	96.3415
ENSG00000247315	homo_sapiens	ENSP00000484056	98.5112	98.0149	chlorocebus_sabaeus	ENSCSAP00000018283	98.7562	98.2587
ENSG00000247315	homo_sapiens	ENSP00000484056	93.3002	92.804	phocoena_sinus	ENSPSNP00000010420	93.0693	92.5743
ENSG00000247315	homo_sapiens	ENSP00000484056	55.8313	55.8313	panthera_tigris_altaica	ENSPTIP00000007868	99.5575	99.5575
ENSG00000247315	homo_sapiens	ENSP00000484056	89.8263	86.1042	rattus_norvegicus	ENSRNOP00000078043	90.5	86.75
ENSG00000247315	homo_sapiens	ENSP00000484056	94.7891	94.5409	prolemur_simus	ENSPSMP00000003973	95.2618	95.0125
ENSG00000247315	homo_sapiens	ENSP00000484056	90.0744	86.6005	microtus_ochrogaster	ENSMOCP00000003586	91.4358	87.9093
ENSG00000247315	homo_sapiens	ENSP00000484056	83.1265	74.6898	peromyscus_maniculatus_bairdii	ENSPEMP00000031974	82.9208	74.505
ENSG00000247315	homo_sapiens	ENSP00000484056	84.1191	75.1861	peromyscus_maniculatus_bairdii	ENSPEMP00000035955	83.7037	74.8148
ENSG00000247315	homo_sapiens	ENSP00000484056	85.6079	76.6749	peromyscus_maniculatus_bairdii	ENSPEMP00000036603	84.9754	76.1084
ENSG00000247315	homo_sapiens	ENSP00000484056	85.6079	76.6749	peromyscus_maniculatus_bairdii	ENSPEMP00000035303	84.9754	76.1084
ENSG00000247315	homo_sapiens	ENSP00000484056	84.8635	75.9305	peromyscus_maniculatus_bairdii	ENSPEMP00000029866	84.8635	75.9305
ENSG00000247315	homo_sapiens	ENSP00000484056	77.9156	74.6898	peromyscus_maniculatus_bairdii	ENSPEMP00000006972	79.2929	76.0101
ENSG00000247315	homo_sapiens	ENSP00000484056	94.0447	93.0521	bos_mutus	ENSBMUP00000020624	93.8119	92.8218
ENSG00000247315	homo_sapiens	ENSP00000484056	89.5782	87.0968	mus_spicilegus	ENSMSIP00000001697	90.25	87.75
ENSG00000247315	homo_sapiens	ENSP00000484056	77.6675	72.4566	cricetulus_griseus_chok1gshd	ENSCGRP00001009878	86.4641	80.663
ENSG00000247315	homo_sapiens	ENSP00000484056	90.5707	86.8486	cricetulus_griseus_chok1gshd	ENSCGRP00001006742	91.0224	87.2818
ENSG00000247315	homo_sapiens	ENSP00000484056	93.5484	92.0596	pteropus_vampyrus	ENSPVAP00000000165	93.5484	92.0596
ENSG00000247315	homo_sapiens	ENSP00000484056	93.3002	92.5558	rhinolophus_ferrumequinum	ENSRFEP00010020523	93.0693	92.3267
ENSG00000247315	homo_sapiens	ENSP00000484056	94.2928	93.3002	bos_taurus	ENSBTAP00000002733	94.0594	93.0693
ENSG00000247315	homo_sapiens	ENSP00000484056	71.7122	68.7345	heterocephalus_glaber_female	ENSHGLP00000032792	83.526	80.0578
ENSG00000247315	homo_sapiens	ENSP00000484056	98.7593	98.5112	rhinopithecus_bieti	ENSRBIP00000011710	99.005	98.7562
ENSG00000247315	homo_sapiens	ENSP00000484056	95.2854	95.0372	canis_lupus_dingo	ENSCAFP00020004963	95.0495	94.802
ENSG00000247315	homo_sapiens	ENSP00000484056	94.2928	94.0447	sciurus_vulgaris	ENSSVLP00005001225	94.7631	94.5137
ENSG00000247315	homo_sapiens	ENSP00000484056	82.6303	80.6452	procavia_capensis	ENSPCAP00000007475	91.989	89.779
ENSG00000247315	homo_sapiens	ENSP00000484056	89.0819	85.6079	nannospalax_galili	ENSNGAP00000004539	92.2879	88.6889
ENSG00000247315	homo_sapiens	ENSP00000484056	94.0447	93.0521	bos_grunniens	ENSBGRP00000023705	93.8119	92.8218
ENSG00000247315	homo_sapiens	ENSP00000484056	93.3002	92.5558	chinchilla_lanigera	ENSCLAP00000000303	94	93.25
ENSG00000247315	homo_sapiens	ENSP00000484056	93.7965	93.0521	cervus_hanglu_yarkandensis	ENSCHYP00000034482	93.5644	92.8218
ENSG00000247315	homo_sapiens	ENSP00000484056	93.0521	92.3077	catagonus_wagneri	ENSCWAP00000010712	93.5162	92.7681
ENSG00000247315	homo_sapiens	ENSP00000484056	94.0447	92.0596	otolemur_garnettii	ENSOGAP00000019243	93.3498	91.3793
ENSG00000247315	homo_sapiens	ENSP00000484056	96.7742	95.7816	cebus_imitator	ENSCCAP00000002919	96.5347	95.5446
ENSG00000247315	homo_sapiens	ENSP00000484056	94.5409	93.5484	urocitellus_parryii	ENSUPAP00010023689	95.0125	94.015
ENSG00000247315	homo_sapiens	ENSP00000484056	94.2928	93.7965	moschus_moschiferus	ENSMMSP00000021524	94.0594	93.5644
ENSG00000247315	homo_sapiens	ENSP00000484056	98.7593	98.5112	rhinopithecus_roxellana	ENSRROP00000001307	99.005	98.7562
ENSG00000247315	homo_sapiens	ENSP00000484056	89.5782	87.0968	mus_pahari	MGP_PahariEiJ_P0066213	90.25	87.75
ENSG00000247315	homo_sapiens	ENSP00000484056	94.7891	94.5409	propithecus_coquereli	ENSPCOP00000004152	95.2618	95.0125
ENSG00000247315	homo_sapiens	ENSP00000484056	17.3697	8.933	ciona_intestinalis	ENSCINP00000034908	33.1754	17.0616
ENSG00000247315	homo_sapiens	ENSP00000484056	33.0025	19.8511	eptatretus_burgeri	ENSEBUP00000003824	33.8422	20.3562
ENSG00000247315	homo_sapiens	ENSP00000484056	30.5211	21.34	latimeria_chalumnae	ENSLACP00000003325	32.3684	22.6316
ENSG00000247315	homo_sapiens	ENSP00000484056	37.9653	24.0695	latimeria_chalumnae	ENSLACP00000009099	39.5349	25.0646
ENSG00000247315	homo_sapiens	ENSP00000484056	33.2506	22.5806	latimeria_chalumnae	ENSLACP00000002575	40.6061	27.5758
ENSG00000247315	homo_sapiens	ENSP00000484056	19.1067	12.4069	lepisosteus_oculatus	ENSLOCP00000022211	44.7674	29.0698
ENSG00000247315	homo_sapiens	ENSP00000484056	28.7841	17.3697	carassius_auratus	ENSCARP00000125231	33.8192	20.4082
ENSG00000247315	homo_sapiens	ENSP00000484056	26.0546	16.3772	astyanax_mexicanus	ENSAMXP00000028690	32.0122	20.122
ENSG00000247315	homo_sapiens	ENSP00000484056	20.5955	12.4069	astyanax_mexicanus	ENSAMXP00000047925	40.0966	24.1546
ENSG00000247315	homo_sapiens	ENSP00000484056	24.8139	14.3921	ictalurus_punctatus	ENSIPUP00000019349	24.6914	14.321
ENSG00000247315	homo_sapiens	ENSP00000484056	17.1216	10.67	esox_lucius	ENSELUP00000041690	45.3947	28.2895
ENSG00000247315	homo_sapiens	ENSP00000484056	18.6104	12.1588	electrophorus_electricus	ENSEEEP00000045017	24.7525	16.1716
ENSG00000247315	homo_sapiens	ENSP00000484056	16.6253	11.4144	electrophorus_electricus	ENSEEEP00000006091	34.5361	23.7113
ENSG00000247315	homo_sapiens	ENSP00000484056	17.3697	12.4069	electrophorus_electricus	ENSEEEP00000006124	21.875	15.625
ENSG00000247315	homo_sapiens	ENSP00000484056	11.1663	8.43672	electrophorus_electricus	ENSEEEP00000005945	26.6272	20.1183
ENSG00000247315	homo_sapiens	ENSP00000484056	22.3325	13.8958	electrophorus_electricus	ENSEEEP00000025355	24.2588	15.0943
ENSG00000247315	homo_sapiens	ENSP00000484056	11.1663	7.69231	electrophorus_electricus	ENSEEEP00000005514	28.3019	19.4969
ENSG00000247315	homo_sapiens	ENSP00000484056	16.8734	11.1663	electrophorus_electricus	ENSEEEP00000005582	35.0515	23.1959
ENSG00000247315	homo_sapiens	ENSP00000484056	23.5732	13.6476	electrophorus_electricus	ENSEEEP00000019049	32.646	18.9003
ENSG00000247315	homo_sapiens	ENSP00000484056	21.5881	13.6476	electrophorus_electricus	ENSEEEP00000006273	26.3636	16.6667
ENSG00000247315	homo_sapiens	ENSP00000484056	12.4069	8.18859	electrophorus_electricus	ENSEEEP00000006090	27.3224	18.0328
ENSG00000247315	homo_sapiens	ENSP00000484056	29.7767	19.603	oncorhynchus_kisutch	ENSOKIP00005072464	26.3736	17.3626
ENSG00000247315	homo_sapiens	ENSP00000484056	27.7916	15.6328	oncorhynchus_mykiss	ENSOMYP00000014535	32	18
ENSG00000247315	homo_sapiens	ENSP00000484056	28.0397	14.8883	oncorhynchus_mykiss	ENSOMYP00000134801	32.0113	16.9972
ENSG00000247315	homo_sapiens	ENSP00000484056	28.2878	15.6328	oncorhynchus_mykiss	ENSOMYP00000125135	24.359	13.4615
ENSG00000247315	homo_sapiens	ENSP00000484056	27.0471	15.3846	oncorhynchus_mykiss	ENSOMYP00000112608	19.395	11.032
ENSG00000247315	homo_sapiens	ENSP00000484056	27.2953	17.1216	oncorhynchus_mykiss	ENSOMYP00000068418	19.7487	12.3878
ENSG00000247315	homo_sapiens	ENSP00000484056	25.3102	14.3921	oncorhynchus_mykiss	ENSOMYP00000113153	35.5401	20.2091
ENSG00000247315	homo_sapiens	ENSP00000484056	25.8065	14.6402	oncorhynchus_mykiss	ENSOMYP00000054359	29.6296	16.8091
ENSG00000247315	homo_sapiens	ENSP00000484056	26.5509	15.1365	oncorhynchus_mykiss	ENSOMYP00000007864	21.2724	12.1272
ENSG00000247315	homo_sapiens	ENSP00000484056	25.8065	14.6402	oncorhynchus_mykiss	ENSOMYP00000116726	23.7986	13.5011
ENSG00000247315	homo_sapiens	ENSP00000484056	28.0397	15.3846	oncorhynchus_mykiss	ENSOMYP00000054603	29.4271	16.1458
ENSG00000247315	homo_sapiens	ENSP00000484056	27.7916	15.8809	oncorhynchus_mykiss	ENSOMYP00000119891	27.2506	15.5718
ENSG00000247315	homo_sapiens	ENSP00000484056	27.7916	15.8809	oncorhynchus_mykiss	ENSOMYP00000140384	32	18.2857
ENSG00000247315	homo_sapiens	ENSP00000484056	28.2878	15.3846	oncorhynchus_mykiss	ENSOMYP00000010392	27.2727	14.8325
ENSG00000247315	homo_sapiens	ENSP00000484056	12.6551	8.933	salmo_salar	ENSSSAP00000106978	28.8136	20.339
ENSG00000247315	homo_sapiens	ENSP00000484056	26.5509	15.6328	salmo_salar	ENSSSAP00000035699	33.5423	19.7492
ENSG00000247315	homo_sapiens	ENSP00000484056	13.3995	9.67742	salmo_salar	ENSSSAP00000018354	32.1429	23.2143
ENSG00000247315	homo_sapiens	ENSP00000484056	26.3027	15.3846	salmo_salar	ENSSSAP00000142464	41.5686	24.3137
ENSG00000247315	homo_sapiens	ENSP00000484056	24.5658	14.8883	salmo_salar	ENSSSAP00000025684	28.863	17.4927
ENSG00000247315	homo_sapiens	ENSP00000484056	24.3176	14.3921	salmo_salar	ENSSSAP00000118193	28.1609	16.6667
ENSG00000247315	homo_sapiens	ENSP00000484056	26.5509	15.3846	salmo_salar	ENSSSAP00000146114	23.3624	13.5371
ENSG00000247315	homo_sapiens	ENSP00000484056	13.3995	9.92556	salmo_salar	ENSSSAP00000018364	31.9527	23.6686
ENSG00000247315	homo_sapiens	ENSP00000484056	13.3995	9.67742	salmo_trutta	ENSSTUP00000064589	30.8571	22.2857
ENSG00000247315	homo_sapiens	ENSP00000484056	11.9107	9.18114	salmo_trutta	ENSSTUP00000008374	28.7425	22.1557
ENSG00000247315	homo_sapiens	ENSP00000484056	12.9032	8.933	salmo_trutta	ENSSTUP00000065699	31.3253	21.6867
ENSG00000247315	homo_sapiens	ENSP00000484056	23.5732	15.1365	salmo_trutta	ENSSTUP00000065820	28.8754	18.541
ENSG00000247315	homo_sapiens	ENSP00000484056	25.5583	14.3921	salmo_trutta	ENSSTUP00000007896	30.5638	17.2107
ENSG00000247315	homo_sapiens	ENSP00000484056	11.9107	8.933	salmo_trutta	ENSSTUP00000007965	24.7423	18.5567
ENSG00000247315	homo_sapiens	ENSP00000484056	23.8213	14.8883	salmo_trutta	ENSSTUP00000058519	28.4866	17.8042
ENSG00000247315	homo_sapiens	ENSP00000484056	26.3027	15.1365	salmo_trutta	ENSSTUP00000006538	21.9462	12.6294
ENSG00000247315	homo_sapiens	ENSP00000484056	12.4069	8.933	salmo_trutta	ENSSTUP00000008061	29.0698	20.9302
ENSG00000247315	homo_sapiens	ENSP00000484056	30.0248	20.8437	gadus_morhua	ENSGMOP00000030042	29.8765	20.7407
ENSG00000247315	homo_sapiens	ENSP00000484056	30.273	21.0918	gadus_morhua	ENSGMOP00000058507	30.1235	20.9877
ENSG00000247315	homo_sapiens	ENSP00000484056	30.273	21.0918	gadus_morhua	ENSGMOP00000031184	30.8081	21.4646
ENSG00000247315	homo_sapiens	ENSP00000484056	30.273	21.0918	gadus_morhua	ENSGMOP00000040862	29.6117	20.6311
ENSG00000247315	homo_sapiens	ENSP00000484056	30.273	21.0918	gadus_morhua	ENSGMOP00000057288	30.1235	20.9877
ENSG00000247315	homo_sapiens	ENSP00000484056	30.0248	20.8437	gadus_morhua	ENSGMOP00000038737	29.8765	20.7407
ENSG00000247315	homo_sapiens	ENSP00000484056	29.5285	18.3623	fundulus_heteroclitus	ENSFHEP00000014582	35.2071	21.8935
ENSG00000247315	homo_sapiens	ENSP00000484056	21.8362	14.6402	poecilia_reticulata	ENSPREP00000025343	42.3077	28.3654
ENSG00000247315	homo_sapiens	ENSP00000484056	28.2878	17.866	poecilia_reticulata	ENSPREP00000006991	34.4411	21.7523
ENSG00000247315	homo_sapiens	ENSP00000484056	31.2655	23.0769	xiphophorus_maculatus	ENSXMAP00000039143	29.6471	21.8824
ENSG00000247315	homo_sapiens	ENSP00000484056	28.536	19.8511	oreochromis_niloticus	ENSONIP00000049228	27.7108	19.2771
ENSG00000247315	homo_sapiens	ENSP00000484056	20.3474	13.8958	haplochromis_burtoni	ENSHBUP00000021722	42.268	28.866
ENSG00000247315	homo_sapiens	ENSP00000484056	26.799	18.3623	haplochromis_burtoni	ENSHBUP00000018775	31.3953	21.5116
ENSG00000247315	homo_sapiens	ENSP00000484056	30.0248	19.603	haplochromis_burtoni	ENSHBUP00000004562	44.4853	29.0441
ENSG00000247315	homo_sapiens	ENSP00000484056	20.3474	14.6402	haplochromis_burtoni	ENSHBUP00000010154	39.2345	28.2297
ENSG00000247315	homo_sapiens	ENSP00000484056	29.2804	19.1067	astatotilapia_calliptera	ENSACLP00000035848	34.5029	22.5146
ENSG00000247315	homo_sapiens	ENSP00000484056	21.8362	13.8958	astatotilapia_calliptera	ENSACLP00000023373	42.7184	27.1845
ENSG00000247315	homo_sapiens	ENSP00000484056	27.5434	17.866	astatotilapia_calliptera	ENSACLP00000029117	26.747	17.3494
ENSG00000247315	homo_sapiens	ENSP00000484056	22.3325	14.1439	astatotilapia_calliptera	ENSACLP00000016604	43.0622	27.2727
ENSG00000247315	homo_sapiens	ENSP00000484056	27.7916	17.866	astatotilapia_calliptera	ENSACLP00000029215	27.2506	17.5182
ENSG00000247315	homo_sapiens	ENSP00000484056	17.6179	12.6551	astatotilapia_calliptera	ENSACLP00000029392	45.2229	32.4841
ENSG00000247315	homo_sapiens	ENSP00000484056	33.2506	21.8362	astatotilapia_calliptera	ENSACLP00000038862	28.7554	18.8841
ENSG00000247315	homo_sapiens	ENSP00000484056	27.0471	16.8734	astatotilapia_calliptera	ENSACLP00000029141	22.5207	14.0496
ENSG00000247315	homo_sapiens	ENSP00000484056	22.5806	14.6402	astatotilapia_calliptera	ENSACLP00000020614	42.723	27.6995
ENSG00000247315	homo_sapiens	ENSP00000484056	22.8288	14.6402	sparus_aurata	ENSSAUP00010038145	44.878	28.7805
ENSG00000247315	homo_sapiens	ENSP00000484056	13.6476	10.1737	sparus_aurata	ENSSAUP00010048203	41.0448	30.597
ENSG00000247315	homo_sapiens	ENSP00000484056	13.3995	9.18114	sparus_aurata	ENSSAUP00010061369	39.1304	26.8116
ENSG00000247315	homo_sapiens	ENSP00000484056	29.0323	18.1141	sparus_aurata	ENSSAUP00010048212	32.5	20.2778
ENSG00000247315	homo_sapiens	ENSP00000484056	13.1514	9.18114	sparus_aurata	ENSSAUP00010038161	32.3171	22.561
ENSG00000247315	homo_sapiens	ENSP00000484056	13.3995	9.92556	sparus_aurata	ENSSAUP00010038156	43.2	32
ENSG00000247315	homo_sapiens	ENSP00000484056	19.1067	15.3846	lates_calcarifer	ENSLCAP00010036615	23.2628	18.7311
ENSG00000247315	homo_sapiens	ENSP00000484056	19.3548	15.3846	lates_calcarifer	ENSLCAP00010049697	23.565	18.7311
ENSG00000247315	homo_sapiens	ENSP00000484056	19.1067	15.3846	lates_calcarifer	ENSLCAP00010004413	23.2628	18.7311
ENSG00000247315	homo_sapiens	ENSP00000484056	19.1067	15.3846	lates_calcarifer	ENSLCAP00010015629	23.2628	18.7311
ENSG00000247315	homo_sapiens	ENSP00000484056	37.9653	25.8065	xenopus_tropicalis	ENSXETP00000105096	16.9435	11.5172
ENSG00000247315	homo_sapiens	ENSP00000484056	35.2357	23.8213	xenopus_tropicalis	ENSXETP00000099993	31.0044	20.9607
ENSG00000247315	homo_sapiens	ENSP00000484056	37.7171	25.5583	xenopus_tropicalis	ENSXETP00000098734	16.1874	10.9691
ENSG00000247315	homo_sapiens	ENSP00000484056	33.0025	22.0844	xenopus_tropicalis	ENSXETP00000075637	33.5013	22.4181
ENSG00000247315	homo_sapiens	ENSP00000484056	31.5136	21.0918	xenopus_tropicalis	ENSXETP00000101994	16.623	11.1257
ENSG00000247315	homo_sapiens	ENSP00000484056	36.9727	22.5806	anolis_carolinensis	ENSACAP00000023559	38.0102	23.2143
ENSG00000247315	homo_sapiens	ENSP00000484056	37.9653	24.0695	anolis_carolinensis	ENSACAP00000029360	34.5372	21.8962
ENSG00000247315	homo_sapiens	ENSP00000484056	22.3325	14.8883	anolis_carolinensis	ENSACAP00000037893	18.75	12.5
ENSG00000247315	homo_sapiens	ENSP00000484056	41.6873	26.0546	anolis_carolinensis	ENSACAP00000040373	10.5329	6.58307
ENSG00000247315	homo_sapiens	ENSP00000484056	41.6873	25.3102	anolis_carolinensis	ENSACAP00000023077	14.3836	8.73288
ENSG00000247315	homo_sapiens	ENSP00000484056	20.5955	13.8958	neolamprologus_brichardi	ENSNBRP00000031705	41.9192	28.2828
ENSG00000247315	homo_sapiens	ENSP00000484056	30.7692	19.3548	erpetoichthys_calabaricus	ENSECRP00000003118	38.0368	23.9264
ENSG00000247315	homo_sapiens	ENSP00000484056	17.6179	12.1588	erpetoichthys_calabaricus	ENSECRP00000008313	40.8046	28.1609
ENSG00000247315	homo_sapiens	ENSP00000484056	31.7618	19.8511	erpetoichthys_calabaricus	ENSECRP00000020628	33.1606	20.7254
ENSG00000247315	homo_sapiens	ENSP00000484056	29.7767	19.1067	erpetoichthys_calabaricus	ENSECRP00000022441	38.835	24.9191
ENSG00000247315	homo_sapiens	ENSP00000484056	31.7618	19.8511	erpetoichthys_calabaricus	ENSECRP00000020561	33.1606	20.7254
ENSG00000247315	homo_sapiens	ENSP00000484056	29.7767	18.8586	erpetoichthys_calabaricus	ENSECRP00000032150	39.604	25.0825
ENSG00000247315	homo_sapiens	ENSP00000484056	31.5136	19.1067	erpetoichthys_calabaricus	ENSECRP00000031921	34.4173	20.8672
ENSG00000247315	homo_sapiens	ENSP00000484056	26.5509	15.1365	erpetoichthys_calabaricus	ENSECRP00000031296	33.8608	19.3038
ENSG00000247315	homo_sapiens	ENSP00000484056	29.5285	20.3474	erpetoichthys_calabaricus	ENSECRP00000032227	36.5031	25.1534
ENSG00000247315	homo_sapiens	ENSP00000484056	32.0099	19.603	erpetoichthys_calabaricus	ENSECRP00000032171	33.5065	20.5195
ENSG00000247315	homo_sapiens	ENSP00000484056	30.5211	18.6104	erpetoichthys_calabaricus	ENSECRP00000028180	33.6986	20.5479
ENSG00000247315	homo_sapiens	ENSP00000484056	15.3846	11.1663	amphilophus_citrinellus	ENSACIP00000022475	40.2597	29.2208
ENSG00000247315	homo_sapiens	ENSP00000484056	18.8586	12.1588	gasterosteus_aculeatus	ENSGACP00000000996	43.6782	28.1609
ENSG00000247315	homo_sapiens	ENSP00000484056	18.8586	12.1588	gasterosteus_aculeatus	ENSGACP00000023875	44.7059	28.8235
ENSG00000247315	homo_sapiens	ENSP00000484056	29.5285	18.8586	poecilia_formosa	ENSPFOP00000029247	47.6	30.4
ENSG00000247315	homo_sapiens	ENSP00000484056	12.1588	9.42928	myripristis_murdjan	ENSMMDP00005027542	30.8176	23.8994
ENSG00000247315	homo_sapiens	ENSP00000484056	12.9032	9.92556	myripristis_murdjan	ENSMMDP00005009281	30.7692	23.6686
ENSG00000247315	homo_sapiens	ENSP00000484056	12.1588	9.18114	myripristis_murdjan	ENSMMDP00005009229	30.0613	22.6994
ENSG00000247315	homo_sapiens	ENSP00000484056	19.8511	15.6328	sander_lucioperca	ENSSLUP00000007049	49.3827	38.8889
ENSG00000247315	homo_sapiens	ENSP00000484056	21.5881	15.3846	hucho_hucho	ENSHHUP00000077530	24.7863	17.6638
ENSG00000247315	homo_sapiens	ENSP00000484056	21.5881	15.3846	hucho_hucho	ENSHHUP00000012772	24.7863	17.6638
ENSG00000247315	homo_sapiens	ENSP00000484056	26.0546	17.6179	betta_splendens	ENSBSLP00000009586	26.5152	17.9293
ENSG00000247315	homo_sapiens	ENSP00000484056	11.1663	8.18859	pygocentrus_nattereri	ENSPNAP00000008187	31.9149	23.4043
ENSG00000247315	homo_sapiens	ENSP00000484056	21.5881	15.1365	pygocentrus_nattereri	ENSPNAP00000028658	21.4286	15.0246
ENSG00000247315	homo_sapiens	ENSP00000484056	17.3697	11.6625	pygocentrus_nattereri	ENSPNAP00000016722	36.4583	24.4792
ENSG00000247315	homo_sapiens	ENSP00000484056	23.3251	14.6402	pygocentrus_nattereri	ENSPNAP00000027303	22.542	14.1487
ENSG00000247315	homo_sapiens	ENSP00000484056	15.3846	10.1737	pygocentrus_nattereri	ENSPNAP00000020100	32.4607	21.466
ENSG00000247315	homo_sapiens	ENSP00000484056	21.5881	13.6476	pygocentrus_nattereri	ENSPNAP00000035171	28.0645	17.7419
ENSG00000247315	homo_sapiens	ENSP00000484056	21.0918	14.3921	pygocentrus_nattereri	ENSPNAP00000036647	21.9072	14.9485
ENSG00000247315	homo_sapiens	ENSP00000484056	20.8437	14.6402	pygocentrus_nattereri	ENSPNAP00000006789	20.9476	14.7132
ENSG00000247315	homo_sapiens	ENSP00000484056	19.1067	13.3995	anabas_testudineus	ENSATEP00000005234	48.125	33.75
ENSG00000247315	homo_sapiens	ENSP00000484056	21.8362	14.8883	anabas_testudineus	ENSATEP00000006506	46.3158	31.5789
ENSG00000247315	homo_sapiens	ENSP00000484056	14.1439	11.9107	pundamilia_nyererei	ENSPNYP00000021112	37.5	31.5789
ENSG00000247315	homo_sapiens	ENSP00000484056	29.2804	18.8586	pundamilia_nyererei	ENSPNYP00000021150	33.1461	21.3483
ENSG00000247315	homo_sapiens	ENSP00000484056	20.5955	13.8958	pundamilia_nyererei	ENSPNYP00000003402	47.7011	32.1839
ENSG00000247315	homo_sapiens	ENSP00000484056	27.5434	18.6104	pundamilia_nyererei	ENSPNYP00000021137	31.1798	21.0674
ENSG00000247315	homo_sapiens	ENSP00000484056	27.0471	16.8734	pundamilia_nyererei	ENSPNYP00000004889	26.7157	16.6667
ENSG00000247315	homo_sapiens	ENSP00000484056	26.3027	15.3846	mastacembelus_armatus	ENSMAMP00000049183	28.5714	16.7116
ENSG00000247315	homo_sapiens	ENSP00000484056	23.8213	13.1514	oncorhynchus_tshawytscha	ENSOTSP00005082824	29.0909	16.0606
ENSG00000247315	homo_sapiens	ENSP00000484056	19.603	12.4069	oncorhynchus_tshawytscha	ENSOTSP00005047474	37.799	23.9234
ENSG00000247315	homo_sapiens	ENSP00000484056	17.3697	11.1663	oncorhynchus_tshawytscha	ENSOTSP00005061085	32.8638	21.1268
ENSG00000247315	homo_sapiens	ENSP00000484056	24.8139	14.1439	oncorhynchus_tshawytscha	ENSOTSP00005045135	33.0033	18.8119
ENSG00000247315	homo_sapiens	ENSP00000484056	26.0546	14.8883	oncorhynchus_tshawytscha	ENSOTSP00005085869	39.7727	22.7273
ENSG00000247315	homo_sapiens	ENSP00000484056	13.1514	9.42928	oncorhynchus_tshawytscha	ENSOTSP00005037968	34.6405	24.8366
ENSG00000247315	homo_sapiens	ENSP00000484056	24.3176	13.8958	oncorhynchus_tshawytscha	ENSOTSP00005049530	41.3502	23.6287
ENSG00000247315	homo_sapiens	ENSP00000484056	13.8958	9.92556	oncorhynchus_tshawytscha	ENSOTSP00005018146	35.2201	25.1572
ENSG00000247315	homo_sapiens	ENSP00000484056	18.1141	11.6625	oncorhynchus_tshawytscha	ENSOTSP00005103503	36.3184	23.3831
ENSG00000247315	homo_sapiens	ENSP00000484056	27.2953	15.3846	oncorhynchus_tshawytscha	ENSOTSP00005099693	38.7324	21.831
ENSG00000247315	homo_sapiens	ENSP00000484056	19.603	12.4069	oncorhynchus_tshawytscha	ENSOTSP00005064184	34.3478	21.7391
ENSG00000247315	homo_sapiens	ENSP00000484056	19.8511	12.1588	oncorhynchus_tshawytscha	ENSOTSP00005050468	32.1285	19.6787
ENSG00000247315	homo_sapiens	ENSP00000484056	23.5732	13.6476	acanthochromis_polyacanthus	ENSAPOP00000012458	38.3064	22.1774
ENSG00000247315	homo_sapiens	ENSP00000484056	30.0248	19.8511	nothobranchius_furzeri	ENSNFUP00015029270	30.5556	20.202
ENSG00000247315	homo_sapiens	ENSP00000484056	23.8213	14.6402	denticeps_clupeoides	ENSDCDP00000006332	27.6657	17.0029
ENSG00000247315	homo_sapiens	ENSP00000484056	24.3176	14.3921	denticeps_clupeoides	ENSDCDP00000014920	36.7041	21.7228
ENSG00000247315	homo_sapiens	ENSP00000484056	18.3623	11.9107	denticeps_clupeoides	ENSDCDP00000011497	35.7488	23.1884
ENSG00000247315	homo_sapiens	ENSP00000484056	22.3325	14.1439	denticeps_clupeoides	ENSDCDP00000014184	26.087	16.5217
ENSG00000247315	homo_sapiens	ENSP00000484056	18.8586	11.9107	denticeps_clupeoides	ENSDCDP00000017764	36.8932	23.301
ENSG00000247315	homo_sapiens	ENSP00000484056	21.0918	12.1588	denticeps_clupeoides	ENSDCDP00000011633	35.4167	20.4167
ENSG00000247315	homo_sapiens	ENSP00000484056	11.4144	8.43672	denticeps_clupeoides	ENSDCDP00000054727	27.2189	20.1183
ENSG00000247315	homo_sapiens	ENSP00000484056	24.0695	13.6476	denticeps_clupeoides	ENSDCDP00000013780	25.3264	14.3603
ENSG00000247315	homo_sapiens	ENSP00000484056	14.6402	9.92556	cyprinus_carpio_carpio	ENSCCRP00000120246	31.7204	21.5054
ENSG00000247315	homo_sapiens	ENSP00000484056	21.5881	15.6328	cyprinus_carpio_carpio	ENSCCRP00000106988	35.8025	25.9259
ENSG00000247315	homo_sapiens	ENSP00000484056	20.3474	14.6402	sinocyclocheilus_grahami	ENSSGRP00000105685	43.3862	31.2169
ENSG00000247315	homo_sapiens	ENSP00000484056	17.3697	13.1514	sinocyclocheilus_grahami	ENSSGRP00000055487	42.4242	32.1212
ENSG00000247315	homo_sapiens	ENSP00000484056	22.0844	14.1439	maylandia_zebra	ENSMZEP00005038171	42.7885	27.4038
ENSG00000247315	homo_sapiens	ENSP00000484056	27.2953	17.3697	maylandia_zebra	ENSMZEP00005000163	27.5689	17.5439
ENSG00000247315	homo_sapiens	ENSP00000484056	32.7543	21.0918	maylandia_zebra	ENSMZEP00005028446	33.5878	21.6285
ENSG00000247315	homo_sapiens	ENSP00000484056	18.1141	12.4069	maylandia_zebra	ENSMZEP00005038170	36.3184	24.8756
ENSG00000247315	homo_sapiens	ENSP00000484056	21.8362	13.3995	maylandia_zebra	ENSMZEP00005037732	41.5094	25.4717
ENSG00000247315	homo_sapiens	ENSP00000484056	24.8139	15.6328	maylandia_zebra	ENSMZEP00005037729	24.7525	15.5941
ENSG00000247315	homo_sapiens	ENSP00000484056	27.5434	17.3697	maylandia_zebra	ENSMZEP00005037731	26.555	16.7464
ENSG00000247315	homo_sapiens	ENSP00000484056	26.3027	16.8734	maylandia_zebra	ENSMZEP00005032926	26.4339	16.9576
ENSG00000247315	homo_sapiens	ENSP00000484056	12.1588	8.68486	maylandia_zebra	ENSMZEP00005034622	21.3974	15.2838
ENSG00000247315	homo_sapiens	ENSP00000484056	27.7916	17.6179	maylandia_zebra	ENSMZEP00005034616	26.8585	17.0264
ENSG00000247315	homo_sapiens	ENSP00000484056	27.5434	16.8734	maylandia_zebra	ENSMZEP00005010972	31.5341	19.3182
ENSG00000247315	homo_sapiens	ENSP00000484056	27.5434	17.6179	maylandia_zebra	ENSMZEP00005034617	26.6187	17.0264
ENSG00000247315	homo_sapiens	ENSP00000484056	27.7916	17.6179	maylandia_zebra	ENSMZEP00005034614	26.8585	17.0264
ENSG00000247315	homo_sapiens	ENSP00000484056	29.5285	19.3548	maylandia_zebra	ENSMZEP00005000540	34.7953	22.807
ENSG00000247315	homo_sapiens	ENSP00000484056	11.4144	8.18859	paramormyrops_kingsleyae	ENSPKIP00000037936	30.8725	22.1477
ENSG00000247315	homo_sapiens	ENSP00000484056	21.0918	12.9032	paramormyrops_kingsleyae	ENSPKIP00000037968	37.6106	23.0089
ENSG00000247315	homo_sapiens	ENSP00000484056	20.0993	12.1588	paramormyrops_kingsleyae	ENSPKIP00000015119	35.3712	21.3974
ENSG00000247315	homo_sapiens	ENSP00000484056	23.3251	14.3921	scleropages_formosus	ENSSFOP00015049309	23.2673	14.3564
ENSG00000247315	homo_sapiens	ENSP00000484056	11.6625	8.43672	scleropages_formosus	ENSSFOP00015037543	27.6471	20
ENSG00000247315	homo_sapiens	ENSP00000484056	22.0844	13.8958	scleropages_formosus	ENSSFOP00015019268	26.0997	16.4223
ENSG00000247315	homo_sapiens	ENSP00000484056	25.8065	17.6179	leptobrachium_leishanense	ENSLLEP00000041568	15.8295	10.8067
ENSG00000247315	homo_sapiens	ENSP00000484056	16.6253	12.4069	leptobrachium_leishanense	ENSLLEP00000011674	43.2258	32.2581

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0002218	involved_in activation of innate immune response	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0003690	enables double-stranded DNA binding	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0009597	involved_in detection of virus	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0032481	involved_in positive regulation of type I interferon production	1	IBA	Homo_sapiens(9606)	Process
GO:0045087	involved_in innate immune response	1	IEA	Homo_sapiens(9606)	Process
GO:0051607	involved_in defense response to virus	1	IBA	Homo_sapiens(9606)	Process
GO:0071360	involved_in cellular response to exogenous dsRNA	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:1900246	involved_in positive regulation of RIG-I signaling pathway	2	IBA,IDA	Homo_sapiens(9606)	Process