RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	N.A.
Localizations	Stress granule or P-body
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000243927	Gene ID	64968	Accession	14051
Symbol	MRPS6	Alias	S6mt;bS6m;RPMS6;MRP-S6;C21orf101	Full Name	mitochondrial ribosomal protein S6
Status	Confidence	Length	69453 bases	Strand	Plus strand
Position	21 : 34073578 - 34143030	RNA binding domain	Ribosomal_S6
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q. [provided by RefSeq, Jul 2008]