RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000243056	Gene ID	8637	Accession	3290
Symbol	EIF4EBP3	Alias	4EBP3;4E-BP3	Full Name	eukaryotic translation initiation factor 4E binding protein 3
Status	Confidence	Length	1915 bases	Strand	Plus strand
Position	5 : 140547662 - 140549576	RNA binding domain	eIF_4EBP
Summary	This gene encodes a member of the EIF4EBP family, which consists of proteins that bind to eukaryotic translation initiation factor 4E and regulate its assembly into EIF4F, the multi-subunit translation initiation factor that recognizes the mRNA cap structure. Read-through transcription from the neighboring upstream gene (MASK or ANKHD1) generates a transcript (MASK-BP3) that encodes a protein comprised of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Oct 2010]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000308472	eIF_4EBP	PF05456	5.5e-36	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
EIF4EBP3-201	ENST00000310331	693	100aa	ENSP00000308472

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0008190	enables eukaryotic initiation factor 4E binding	1	IBA	Homo_sapiens(9606)	Function
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0016281	part_of eukaryotic translation initiation factor 4F complex	1	NAS	Homo_sapiens(9606)	Component
GO:0030371	enables translation repressor activity	1	NAS	Homo_sapiens(9606)	Function
GO:0045947	involved_in negative regulation of translational initiation	2	IBA,NAS	Homo_sapiens(9606)	Process