RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000241973	Gene ID	5297	Accession	8983
Symbol	PI4KA	Alias	SPG84;GIDID2;PIK4CA;PMGYCHA;pi4K230;PI4K-ALPHA	Full Name	phosphatidylinositol 4-kinase alpha
Status	Confidence	Length	151727 bases	Strand	Minus strand
Position	22 : 20707691 - 20859417	RNA binding domain	N.A.
Summary	This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2018]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
PI4KA-201	ENST00000255882	6751	2102aa	ENSP00000255882
PI4KA-217	ENST00000492581	3925	No protein	-
PI4KA-209	ENST00000477245	3026	No protein	-
PI4KA-207	ENST00000466772	3109	No protein	-
PI4KA-202	ENST00000399213	1636	435aa	ENSP00000382162
PI4KA-211	ENST00000482030	655	No protein	-
PI4KA-206	ENST00000466394	782	No protein	-
PI4KA-216	ENST00000489966	290	No protein	-
PI4KA-213	ENST00000485123	455	No protein	-
PI4KA-204	ENST00000462210	560	No protein	-
PI4KA-210	ENST00000477368	535	No protein	-
PI4KA-218	ENST00000494113	515	No protein	-
PI4KA-208	ENST00000475414	400	No protein	-
PI4KA-205	ENST00000466162	589	No protein	-
PI4KA-212	ENST00000484220	646	No protein	-
PI4KA-215	ENST00000485963	2301	No protein	-
PI4KA-214	ENST00000485950	479	No protein	-
PI4KA-203	ENST00000449120	574	87aa	ENSP00000402437

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0004430	enables 1-phosphatidylinositol 4-kinase activity	3	IBA,ISS,TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005737	is_active_in cytoplasm	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0005886	is_active_in plasma membrane	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005925	located_in focal adhesion	1	HDA	Homo_sapiens(9606)	Component
GO:0006661	involved_in phosphatidylinositol biosynthetic process	1	TAS	Homo_sapiens(9606)	Process
GO:0007165	involved_in signal transduction	1	NAS	Homo_sapiens(9606)	Process
GO:0016020	located_in membrane	1	HDA	Homo_sapiens(9606)	Component
GO:0016301	enables kinase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0016310	acts_upstream_of_or_within phosphorylation	1	IDA	Homo_sapiens(9606)	Process
GO:0030660	located_in Golgi-associated vesicle membrane	1	ISS	Homo_sapiens(9606)	Component
GO:0044788	involved_in modulation by host of viral process	1	IMP	Homo_sapiens(9606)	Process
GO:0045296	enables cadherin binding	1	HDA	Homo_sapiens(9606)	Function
GO:0046854	involved_in phosphatidylinositol phosphate biosynthetic process	2	IBA,ISS	Homo_sapiens(9606)	Process
GO:0048015	involved_in phosphatidylinositol-mediated signaling	1	IBA	Homo_sapiens(9606)	Process
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component
GO:0140754	involved_in reorganization of cellular membranes to establish viral sites of replication	1	IMP	Homo_sapiens(9606)	Process