RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000240682	Gene ID	57461	Accession	29201
Symbol	ISY1	Alias		Full Name
Status	Confidence	Length	33649 bases	Strand	Minus strand
Position	3 : 129127415 - 129161063	RNA binding domain	Isy1
Summary

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000273541	Isy1	PF06246	2.2e-94	1
ENSP00000376970	Isy1	PF06246	6.8e-87	1
ENSP00000376973	Isy1	PF06246	2.7e-95	1
ENSP00000422403	Isy1	PF06246	1.8e-50	1
ENSP00000426416	Isy1	PF06246	6.5e-53	1

Showing 1 to 5 of 5 entries

RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
22658674	RIC_PMID22658674_Hs_HeLa	HeLa	Alfredo Castello?	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
26632259	RIC_PMID26632259._Hs_HuH7	HuH7	Benedikt M Beckmann	2015 Dec 3	doi: 10.1038/ncomms10127.
30528433	XRNAX_PMID30528433_Hs_HEK293	HEK293	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433_Hs_HeLa	HeLa	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30824702	PtexRIC_PMID30824702_293T_human	293T	Erika C Urdaneta	2019 Mar 1	doi: 10.1038/s41467-019-08942-3
31076284	R.Deep_PMID_31076284_Hs		Maiwen Caudron-Herger	2019 Jul 11	doi: 10.1016/j.molcel.2019.04.018.?Epub 2019 May 7
33235359	RIC_PMID33235359_humanRIC.superset.2021		Fatima Gebauer	2021 Mar	doi: 10.1038/s41576-020-00302-y
33332543	FAX.RIC_PMID33332543_Hela_human	Hela	Yongwoo Na	2021 Mar 18	doi: 10.1093/nar/gkaa1194
33693821	PP.enrichment.RIC_PMID33693821_Hela_human	Hela	Zheng Zhang	2021 Jun 21	doi: 10.1093/nar/gkab156
34077720	RIC_PMID34077720_RIC_hESCs_human	hESC	Shlomi Dvir	2021 Jun 1	doi: 10.1016/j.celrep.2021.109198

Showing 1 to 10 of 13 entries

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Literatures on RNA binding capacity

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Pubmed ID	Title	Author	Time	Journal
29664006	A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans.	Wei Jiang	2018-04-17	eLife

Showing 1 to 1 of 1 entries

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Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
ISY1-201	ENST00000273541	1704	307aa	ENSP00000273541
ISY1-202	ENST00000393292	988	252aa	ENSP00000376970
ISY1-203	ENST00000393295	3612	285aa	ENSP00000376973
ISY1-204	ENST00000471306	552	No protein	-
ISY1-205	ENST00000471497	1211	No protein	-
ISY1-206	ENST00000485703	837	124aa	ENSP00000422403
ISY1-207	ENST00000496163	752	148aa	ENSP00000426416

Showing 1 to 7 of 7 entries

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Gene Model

Click here to download ENSG00000240682's gene model file

ensgID	Trait	pValue	Pubmed ID
No data available in table

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
No data available in table

Protein-Protein Interaction (PPI)

Click here to download ENSG00000240682's PPI file

Orthologs

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Search:

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000240682	homo_sapiens	ENSP00000376973	99.2982	99.2982	nomascus_leucogenys	ENSNLEP00000043104	92.1824	92.1824
ENSG00000240682	homo_sapiens	ENSP00000376973	94.386	93.3333	pan_paniscus	ENSPPAP00000038895	93.7282	92.6829
ENSG00000240682	homo_sapiens	ENSP00000376973	99.2982	99.2982	pongo_abelii	ENSPPYP00000027857	92.1824	92.1824
ENSG00000240682	homo_sapiens	ENSP00000376973	99.2982	99.2982	pan_troglodytes	ENSPTRP00000026473	92.1824	92.1824
ENSG00000240682	homo_sapiens	ENSP00000376973	99.6491	99.6491	gorilla_gorilla	ENSGGOP00000003642	92.5081	92.5081
ENSG00000240682	homo_sapiens	ENSP00000376973	92.2807	85.9649	ornithorhynchus_anatinus	ENSOANP00000020765	94.2652	87.8136
ENSG00000240682	homo_sapiens	ENSP00000376973	95.0877	90.5263	sarcophilus_harrisii	ENSSHAP00000042048	96.0993	91.4894
ENSG00000240682	homo_sapiens	ENSP00000376973	72.9825	69.4737	notamacropus_eugenii	ENSMEUP00000007703	70.5085	67.1186
ENSG00000240682	homo_sapiens	ENSP00000376973	48.4211	48.0702	choloepus_hoffmanni	ENSCHOP00000001245	62.7273	62.2727
ENSG00000240682	homo_sapiens	ENSP00000376973	97.8947	96.8421	dasypus_novemcinctus	ENSDNOP00000015780	97.5524	96.5035

Showing 1 to 10 of 194 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000398	involved_in mRNA splicing, via spliceosome	2	IC,IDA	Homo_sapiens(9606)	Process
GO:0071013	part_of catalytic step 2 spliceosome	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0000350	involved_in generation of catalytic spliceosome for second transesterification step	1	IBA	Homo_sapiens(9606)	Process
GO:0000389	involved_in mRNA 3-splice site recognition	1	IBA	Homo_sapiens(9606)	Process
GO:0000974	part_of Prp19 complex	1	IBA	Homo_sapiens(9606)	Component
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0071006	part_of U2-type catalytic step 1 spliceosome	1	IDA	Homo_sapiens(9606)	Component

Showing 1 to 10 of 12 entries

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression