RBP Type
Canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
Nucleoli
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000234414 Gene ID
5940 Accession
9912
Symbol
RBMY1A1
Alias
RBM;RBM1;RBM2;RBMY;YRRM1;YRRM2;RBMY1C
Full Name
RNA binding motif protein Y-linked family 1 member A1
Status
Confidence
Length
14448 bases
Strand
Plus strand
Position
Y : 21534879 - 21549326
RNA binding domain
RBM1CTR , RRM_1
Summary
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. This protein is thought to function as a splicing regulator during spermatogenesis. Multiple closely related paralogs of this gene are found in a gene cluster in the AZFb azoospermia factor region of chromosome Y. Most of these related copies are thought to be pseudogenes, though several likely encode functional proteins. [provided by RefSeq, Mar 2016]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000372154
RRM_1
PF00076 7e-21
1
ENSP00000372154
RBM1CTR
PF08081 2.3e-21
2
ENSP00000354329
RRM_1
PF00076 9.4e-21
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
26625006 Hypermethylation of genes in testicular embryonal carcinomas.
Hoi-Hung Cheung
2016-01-19
British journal of cancer
28115466 Loss of maternal Trim28 causes male-predominant early embryonic lethality.
Abhishek A Sampath
2017-01-01
Genes & development
31905733 The Role of Number of Copies, Structure, Behavior and Copy Number Variations (CNV) of the Y Chromosome in Male Infertility.
Fabrizio Signore
2019-12-29
Genes
25799347 De novo origin of VCY2 from autosome to Y-transposed amplicon.
Peng-Rong Cao
2015-01-01
PloS one
29637072 A Lexicon of DNA Modifications: Their Roles in Embryo Development and the Germline.
Qifan Zhu
2018-01-01
Frontiers in cell and developmental biology
Name
Transcript ID
bp
Protein
Translation ID
RBMY1A1-202
ENST00000382707
1921
496aa
ENSP00000372154
RBMY1A1-201
ENST00000361046
1718
81aa
ENSP00000354329
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000234414 homo_sapiens ENSP00000295971 12.9848 7.75717 homo_sapiens ENSP00000372154 15.5242 9.27419 ENSG00000234414 homo_sapiens ENSP00000304139 59.4388 48.2143 homo_sapiens ENSP00000372154 46.9758 38.1048 ENSG00000234414 homo_sapiens ENSP00000417451 18.7441 14.3393 homo_sapiens ENSP00000372154 40.3226 30.8468 ENSG00000234414 homo_sapiens ENSP00000478691 34.6041 20.2346 homo_sapiens ENSP00000372154 23.7903 13.9113 ENSG00000234414 homo_sapiens ENSP00000445366 13.3144 7.64873 homo_sapiens ENSP00000372154 9.47581 5.44355 ENSG00000234414 homo_sapiens ENSP00000341826 33.871 19.6237 homo_sapiens ENSP00000372154 25.4032 14.7177 ENSG00000234414 homo_sapiens ENSP00000350090 37.1875 22.1875 homo_sapiens ENSP00000372154 23.9919 14.3145 ENSG00000234414 homo_sapiens ENSP00000493805 38.75 22.8125 homo_sapiens ENSP00000372154 25 14.7177 ENSG00000234414 homo_sapiens ENSP00000376309 32.5397 20.1058 homo_sapiens ENSP00000372154 24.7984 15.3226 ENSG00000234414 homo_sapiens ENSP00000284073 29.5732 17.378 homo_sapiens ENSP00000372154 19.5565 11.4919 ENSG00000234414 homo_sapiens ENSP00000310471 21.727 12.2563 homo_sapiens ENSP00000372154 15.7258 8.87097 ENSG00000234414 homo_sapiens ENSP00000309166 21.1538 11.8132 homo_sapiens ENSP00000372154 15.5242 8.66935 ENSG00000234414 homo_sapiens ENSP00000498248 71.2821 58.7179 homo_sapiens ENSP00000372154 56.0484 46.1694 ENSG00000234414 homo_sapiens ENSP00000359645 73.4015 61.1253 homo_sapiens ENSP00000372154 57.8629 48.1855 ENSG00000234414 homo_sapiens ENSP00000401371 22.0207 11.9171 homo_sapiens ENSP00000372154 17.1371 9.27419 ENSG00000234414 homo_sapiens ENSP00000257552 27.0718 15.4696 homo_sapiens ENSP00000372154 19.7581 11.2903 ENSG00000234414 homo_sapiens ENSP00000281722 14.8218 7.31707 homo_sapiens ENSP00000372154 15.9274 7.8629 ENSG00000234414 homo_sapiens ENSP00000352956 12.9841 7.51708 homo_sapiens ENSP00000372154 11.4919 6.65323 ENSG00000234414 homo_sapiens ENSP00000362936 22.6481 13.5889 homo_sapiens ENSP00000372154 13.1048 7.8629 ENSG00000234414 homo_sapiens ENSP00000313199 26.1972 17.1831 homo_sapiens ENSP00000372154 18.75 12.2984 ENSG00000234414 homo_sapiens ENSP00000253363 11.5094 7.16981 homo_sapiens ENSP00000372154 12.2984 7.66129 ENSG00000234414 homo_sapiens ENSP00000363109 13.1399 7.67918 homo_sapiens ENSP00000372154 15.5242 9.07258 ENSG00000234414 homo_sapiens ENSP00000316042 32.1311 20.6557 homo_sapiens ENSP00000372154 19.7581 12.7016 ENSG00000234414 homo_sapiens ENSP00000318195 12.1127 6.33803 homo_sapiens ENSP00000372154 17.3387 9.07258 ENSG00000234414 homo_sapiens ENSP00000394902 22.4 11.4667 homo_sapiens ENSP00000372154 16.9355 8.66935 ENSG00000234414 homo_sapiens ENSP00000351108 27.1084 17.1687 homo_sapiens ENSP00000372154 18.1452 11.4919 ENSG00000234414 homo_sapiens ENSP00000261741 9.6875 4.58333 homo_sapiens ENSP00000372154 18.75 8.87097 ENSG00000234414 homo_sapiens ENSP00000233078 30.9582 18.6732 homo_sapiens ENSP00000372154 25.4032 15.3226 ENSG00000234414 homo_sapiens ENSP00000295470 20.2381 12.1429 homo_sapiens ENSP00000372154 17.1371 10.2823 ENSG00000234414 homo_sapiens ENSP00000466025 39.0572 28.2828 homo_sapiens ENSP00000372154 23.3871 16.9355 ENSG00000234414 homo_sapiens ENSP00000365950 63.6943 48.4076 homo_sapiens ENSP00000372154 20.1613 15.3226 ENSG00000234414 homo_sapiens ENSP00000372105 99.7984 99.5968 homo_sapiens ENSP00000372154 99.7984 99.5968 ENSG00000234414 homo_sapiens ENSP00000372127 99.7984 99.7984 homo_sapiens ENSP00000372154 99.7984 99.7984 ENSG00000234414 homo_sapiens ENSP00000372484 99.5968 99.5968 homo_sapiens ENSP00000372154 99.5968 99.5968 ENSG00000234414 homo_sapiens ENSP00000307155 99.1936 99.1936 homo_sapiens ENSP00000372154 99.1936 99.1936 ENSG00000234414 homo_sapiens ENSP00000250831 99.1936 99.1936 homo_sapiens ENSP00000372154 99.1936 99.1936
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000234414 homo_sapiens ENSP00000372154 93.1452 91.7339 pan_troglodytes ENSPTRP00000086742 91.6667 90.2778 ENSG00000234414 homo_sapiens ENSP00000372154 90.5242 88.7097 pan_troglodytes ENSPTRP00000087489 91.2602 89.4309 ENSG00000234414 homo_sapiens ENSP00000372154 95.1613 94.1532 pan_troglodytes ENSPTRP00000065125 94.9698 93.9638 ENSG00000234414 homo_sapiens ENSP00000372154 92.7419 91.9355 pan_troglodytes ENSPTRP00000060371 94.2623 93.4426 ENSG00000234414 homo_sapiens ENSP00000372154 92.9436 91.5323 pan_troglodytes ENSPTRP00000063209 91.4683 90.0794 ENSG00000234414 homo_sapiens ENSP00000372154 94.7581 93.75 pan_troglodytes ENSPTRP00000086688 94.5674 93.5614 ENSG00000234414 homo_sapiens ENSP00000372154 87.7016 86.6936 pan_troglodytes ENSPTRP00000064207 93.5484 92.4731 ENSG00000234414 homo_sapiens ENSP00000372154 92.9436 91.5323 pan_troglodytes ENSPTRP00000062985 91.4683 90.0794 ENSG00000234414 homo_sapiens ENSP00000372154 81.25 76.0081 pan_troglodytes ENSPTRP00000065819 85.9275 80.3838 ENSG00000234414 homo_sapiens ENSP00000372154 88.3064 87.0968 pan_troglodytes ENSPTRP00000086775 92.0168 90.7563 ENSG00000234414 homo_sapiens ENSP00000372154 94.9597 93.75 pan_troglodytes ENSPTRP00000070297 94.3888 93.1864 ENSG00000234414 homo_sapiens ENSP00000372154 83.871 80.0403 macaca_fascicularis ENSMFAP00000060089 70.2703 67.0608 ENSG00000234414 homo_sapiens ENSP00000372154 84.0726 80.2419 macaca_mulatta ENSMMUP00000075587 66.2957 63.275 ENSG00000234414 homo_sapiens ENSP00000372154 37.7016 34.6774 macaca_mulatta ENSMMUP00000042043 80.9524 74.4589 ENSG00000234414 homo_sapiens ENSP00000372154 26.8145 23.9919 marmota_marmota_marmota ENSMMMP00000008320 80.6061 72.1212 ENSG00000234414 homo_sapiens ENSP00000372154 42.7419 31.4516 mus_musculus ENSMUSP00000139527 55.7895 41.0526 ENSG00000234414 homo_sapiens ENSP00000372154 42.7419 31.4516 mus_musculus ENSMUSP00000140704 55.7895 41.0526 ENSG00000234414 homo_sapiens ENSP00000372154 42.7419 31.4516 mus_musculus ENSMUSP00000139784 55.7895 41.0526 ENSG00000234414 homo_sapiens ENSP00000372154 42.5403 31.4516 mus_musculus ENSMUSP00000140512 55.5263 41.0526 ENSG00000234414 homo_sapiens ENSP00000372154 22.5806 17.1371 mus_musculus ENSMUSP00000139969 67.4699 51.2048 ENSG00000234414 homo_sapiens ENSP00000372154 42.7419 31.6532 mus_musculus ENSMUSP00000140936 55.7895 41.3158 ENSG00000234414 homo_sapiens ENSP00000372154 42.7419 31.4516 mus_musculus ENSMUSP00000097930 55.7895 41.0526 ENSG00000234414 homo_sapiens ENSP00000372154 42.7419 31.6532 mus_musculus ENSMUSP00000140575 55.7895 41.3158 ENSG00000234414 homo_sapiens ENSP00000372154 42.7419 31.4516 mus_musculus ENSMUSP00000139659 55.7895 41.0526 ENSG00000234414 homo_sapiens ENSP00000372154 43.1452 32.0564 mus_musculus ENSMUSP00000141183 56.3158 41.8421 ENSG00000234414 homo_sapiens ENSP00000372154 71.7742 65.9274 chlorocebus_sabaeus ENSCSAP00000014317 72.8016 66.8712 ENSG00000234414 homo_sapiens ENSP00000372154 44.7581 34.0726 rattus_norvegicus ENSRNOP00000074643 57.2165 43.5567 ENSG00000234414 homo_sapiens ENSP00000372154 12.0968 9.27419 mus_spicilegus ENSMSIP00000005559 75 57.5 ENSG00000234414 homo_sapiens ENSP00000372154 70.5645 67.3387 rhinopithecus_bieti ENSRBIP00000001570 82.9384 79.1469 ENSG00000234414 homo_sapiens ENSP00000372154 26.8145 23.5887 urocitellus_parryii ENSUPAP00010011141 80.6061 70.9091 ENSG00000234414 homo_sapiens ENSP00000372154 70.5645 67.7419 rhinopithecus_roxellana ENSRROP00000010671 83.1354 79.81 ENSG00000234414 homo_sapiens ENSP00000372154 12.5 9.27419 eptatretus_burgeri ENSEBUP00000024062 66.6667 49.4624 ENSG00000234414 homo_sapiens ENSP00000372154 12.9032 9.67742 eptatretus_burgeri ENSEBUP00000011933 68.0851 51.0638
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000381 involved_in regulation of alternative mRNA splicing, via spliceosome 1 IDA Homo_sapiens(9606) Process GO:0003723 enables RNA binding 1 IBA Homo_sapiens(9606) Function GO:0003729 enables mRNA binding 1 IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005654 located_in nucleoplasm 1 IDA Homo_sapiens(9606) Component GO:0005681 part_of spliceosomal complex 1 IBA Homo_sapiens(9606) Component GO:0005730 located_in nucleolus 1 IDA Homo_sapiens(9606) Component GO:0006397 involved_in mRNA processing 1 IEA Homo_sapiens(9606) Process GO:0008380 involved_in RNA splicing 1 IEA Homo_sapiens(9606) Process GO:0048026 involved_in positive regulation of mRNA splicing, via spliceosome 1 IBA Homo_sapiens(9606) Process
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