RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	Cancer Disease
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000229474	Gene ID	197135	Accession	33630
Symbol	PATL2	Alias	OOMD4;Pat1a;OZEMA4;hPat1a	Full Name	PAT1 homolog 2
Status	Confidence	Length	45592 bases	Strand	Minus strand
Position	15 : 44665732 - 44711323	RNA binding domain	PAT1
Summary	Predicted to enable RNA binding activity. Predicted to be involved in P-body assembly and deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to act upstream of or within negative regulation of cytoplasmic mRNA processing body assembly. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000416673	PAT1	PF09770	2.2e-13	1
ENSP00000453695	PAT1	PF09770	7.9e-13	1
ENSP00000508024	PAT1	PF09770	2.2e-13	1

Showing 1 to 3 of 3 entries

Pubmed ID	Full Name	Cell	Author	Time	Doi
No data available in table

Literatures on RNA binding capacity

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Pubmed ID	Title	Author	Time	Journal
29661911	PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice.	Marie Christou-Kent	2018-05-01	EMBO molecular medicine
37218508	PATL2 regulates mRNA homeostasis in oocytes by interacting with EIF4E and CPEB1.	Zhihua Zhang	2023-06-15	Development (Cambridge, England)
37255713	High carrier frequency of pathogenic PATL2 gene mutations predicted in population: a bioinformatics-based approach.	Hao Zhou	2023-01-01	Frontiers in genetics

Showing 1 to 3 of 3 entries

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Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
PATL2-201	ENST00000434130	1951	543aa	ENSP00000416673
PATL2-202	ENST00000558159	867	No protein	-
PATL2-203	ENST00000558481	845	188aa	ENSP00000454201
PATL2-204	ENST00000558573	2100	No protein	-
PATL2-205	ENST00000558809	531	158aa	ENSP00000453723
PATL2-206	ENST00000560110	765	125aa	ENSP00000453898
PATL2-207	ENST00000560780	1863	354aa	ENSP00000453695
PATL2-208	ENST00000561082	559	No protein	-
PATL2-209	ENST00000682850	2410	543aa	ENSP00000508024

Showing 1 to 9 of 9 entries

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Gene Model

Click here to download ENSG00000229474's gene model file

ensgID	Trait	pValue	Pubmed ID
No data available in table

GWAS

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ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
ENSG00000229474	rs181576645	15	44707278	Urinary tract infection frequency	28928442	0.3635	EFO_0008413

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Protein-Protein Interaction (PPI)

Click here to download ENSG00000229474's PPI file

Paralogs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000229474	homo_sapiens	ENSP00000300146	36.7532	23.5065	homo_sapiens	ENSP00000508024	52.1179	33.3333
ENSG00000229474	homo_sapiens	ENST00000633013	22.8956	17.8451	homo_sapiens	ENSP00000508024	12.523	9.76059

Showing 1 to 2 of 2 entries

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Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000229474	homo_sapiens	ENSP00000508024	96.6851	95.5801	nomascus_leucogenys	ENSNLEP00000006883	97.5836	96.4684
ENSG00000229474	homo_sapiens	ENSP00000508024	99.2634	99.0792	pan_paniscus	ENSPPAP00000001602	98.8991	98.7156
ENSG00000229474	homo_sapiens	ENSP00000508024	98.1584	97.4217	pongo_abelii	ENSPPYP00000026496	98.1584	97.4217
ENSG00000229474	homo_sapiens	ENSP00000508024	99.4475	99.2634	pan_troglodytes	ENSPTRP00000061085	99.0826	98.8991
ENSG00000229474	homo_sapiens	ENSP00000508024	98.895	98.7109	gorilla_gorilla	ENSGGOP00000026743	99.0775	98.893
ENSG00000229474	homo_sapiens	ENSP00000508024	49.3554	43.2781	ornithorhynchus_anatinus	ENSOANP00000002449	78.1341	68.5131
ENSG00000229474	homo_sapiens	ENSP00000508024	77.1639	67.035	sarcophilus_harrisii	ENSSHAP00000019997	72.4913	62.9758
ENSG00000229474	homo_sapiens	ENSP00000508024	88.2136	82.1363	dasypus_novemcinctus	ENSDNOP00000022921	81.8803	76.2393
ENSG00000229474	homo_sapiens	ENSP00000508024	63.5359	55.0645	erinaceus_europaeus	ENSEEUP00000004685	78.2313	67.8005
ENSG00000229474	homo_sapiens	ENSP00000508024	57.8269	53.5912	echinops_telfairi	ENSETEP00000004123	88.9518	82.4363

Showing 1 to 10 of 177 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003723	enables RNA binding	2	IBA,ISS	Homo_sapiens(9606)	Function
GO:0000290	involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA	1	IBA	Homo_sapiens(9606)	Process
GO:0000932	is_active_in P-body	1	IBA	Homo_sapiens(9606)	Component
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	ISS	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0010607	involved_in negative regulation of cytoplasmic mRNA processing body assembly	1	IEA	Homo_sapiens(9606)	Process
GO:0017148	involved_in negative regulation of translation	1	ISS	Homo_sapiens(9606)	Process
GO:0033962	involved_in P-body assembly	1	IBA	Homo_sapiens(9606)	Process

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression