RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	Drug
Main interacting RNAs	rRNA
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000229117	Gene ID	6171	Accession	10354
Symbol	RPL41	Alias	L41;eL41	Full Name	ribosomal protein L41
Status	Confidence	Length	1378 bases	Strand	Plus strand
Position	12 : 56116590 - 56117967	RNA binding domain	Ribosomal_L41
Summary	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with the yeast ribosomal protein YL41, belongs to the L41E family of ribosomal proteins. It is located in the cytoplasm. The protein can interact with the beta subunit of protein kinase CKII and can stimulate the phosphorylation of DNA topoisomerase II-alpha by CKII. Two alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000420821	Ribosomal_L41	PF05162	3.7e-11	1
ENSP00000449026	Ribosomal_L41	PF05162	3.7e-11	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
RPL41-202	ENST00000501597	469	25aa	ENSP00000420821
RPL41-203	ENST00000546485	335	No protein	-
RPL41-201	ENST00000358888	551	No protein	-
RPL41-204	ENST00000546591	676	25aa	ENSP00000449026
RPL41-205	ENST00000546654	238	No protein	-
RPL41-206	ENST00000552314	595	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000229117

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000229117	homo_sapiens	ENSP00000449026	100	100	oryctolagus_cuniculus	ENSOCUP00000033163	100	100
ENSG00000229117	homo_sapiens	ENSP00000449026	100	100	aotus_nancymaae	ENSANAP00000042407	100	100
ENSG00000229117	homo_sapiens	ENSP00000449026	100	100	carlito_syrichta	ENSTSYP00000019679	100	100
ENSG00000229117	homo_sapiens	ENSP00000449026	100	100	sphenodon_punctatus	ENSSPUP00000019110	45.4545	45.4545

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0002181	involved_in cytoplasmic translation	2	IDA,NAS	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	1	TAS	Homo_sapiens(9606)	Function
GO:0003730	enables mRNA 3-UTR binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003735	enables structural constituent of ribosome	1	NAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005737	located_in cytoplasm	1	NAS	Homo_sapiens(9606)	Component
GO:0005783	located_in endoplasmic reticulum	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0006412	involved_in translation	1	NAS	Homo_sapiens(9606)	Process
GO:0022625	part_of cytosolic large ribosomal subunit	3	HDA,IDA,IPI	Homo_sapiens(9606)	Component
GO:0042788	located_in polysomal ribosome	1	IDA	Homo_sapiens(9606)	Component
GO:0048027	enables mRNA 5-UTR binding	1	IDA	Homo_sapiens(9606)	Function