RBP Type	Canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	diverse
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000223496	Gene ID	118460	Accession	19055
Symbol	EXOSC6	Alias	p11;EAP4;MTR3;Mtr3p;hMtr3p	Full Name	exosome component 6
Status	Confidence	Length	5163 bases	Strand	Minus strand
Position	16 : 70246778 - 70251940	RNA binding domain	RNase_PH
Summary	This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000398597	RNase_PH	PF01138	6.5e-27	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
35842572	Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates.	J Matthew Munro	2022-07-16	Clinical proteomics

Name	Transcript ID	bp	Protein	Translation ID
EXOSC6-201	ENST00000435634	5163	272aa	ENSP00000398597

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000223496	homo_sapiens	ENSP00000315476	43.6735	27.3469	homo_sapiens	ENSP00000398597	39.3382	24.6324
ENSG00000223496	homo_sapiens	ENSP00000221233	40.8511	28.9362	homo_sapiens	ENSP00000398597	35.2941	25

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000223496	homo_sapiens	ENSP00000398597	99.6324	99.6324	pongo_abelii	ENSPPYP00000008518	99.6324	99.6324
ENSG00000223496	homo_sapiens	ENSP00000398597	99.6324	99.6324	pan_troglodytes	ENSPTRP00000014169	99.6324	99.6324
ENSG00000223496	homo_sapiens	ENSP00000398597	84.5588	81.25	sarcophilus_harrisii	ENSSHAP00000024135	53.1178	51.0393
ENSG00000223496	homo_sapiens	ENSP00000398597	97.0588	95.9559	dasypus_novemcinctus	ENSDNOP00000034874	97.0588	95.9559
ENSG00000223496	homo_sapiens	ENSP00000398597	96.6912	95.9559	callithrix_jacchus	ENSCJAP00000026790	97.4074	96.6667
ENSG00000223496	homo_sapiens	ENSP00000398597	98.1618	97.7941	papio_anubis	ENSPANP00000009514	98.1618	97.7941
ENSG00000223496	homo_sapiens	ENSP00000398597	94.8529	94.4853	capra_hircus	ENSCHIP00000003301	94.8529	94.4853
ENSG00000223496	homo_sapiens	ENSP00000398597	95.5882	94.8529	panthera_leo	ENSPLOP00000020521	95.5882	94.8529
ENSG00000223496	homo_sapiens	ENSP00000398597	96.6912	96.6912	equus_caballus	ENSECAP00000068859	96.6912	96.6912
ENSG00000223496	homo_sapiens	ENSP00000398597	95.5882	95.2206	canis_lupus_familiaris	ENSCAFP00845006960	95.5882	95.2206
ENSG00000223496	homo_sapiens	ENSP00000398597	95.5882	94.8529	panthera_pardus	ENSPPRP00000029008	95.5882	94.8529
ENSG00000223496	homo_sapiens	ENSP00000398597	94.4853	92.6471	balaenoptera_musculus	ENSBMSP00010025143	94.4853	92.6471
ENSG00000223496	homo_sapiens	ENSP00000398597	85.6618	83.4559	cavia_porcellus	ENSCPOP00000023812	94.7154	92.2764
ENSG00000223496	homo_sapiens	ENSP00000398597	85.2941	84.1912	cavia_porcellus	ENSCPOP00000028974	90.625	89.4531
ENSG00000223496	homo_sapiens	ENSP00000398597	95.5882	94.8529	felis_catus	ENSFCAP00000048839	95.5882	94.8529
ENSG00000223496	homo_sapiens	ENSP00000398597	28.3088	27.2059	ursus_americanus	ENSUAMP00000008247	93.9024	90.2439
ENSG00000223496	homo_sapiens	ENSP00000398597	77.5735	74.6324	monodelphis_domestica	ENSMODP00000018146	82.7451	79.6078
ENSG00000223496	homo_sapiens	ENSP00000398597	94.4853	92.2794	monodon_monoceros	ENSMMNP00015002693	94.4853	92.2794
ENSG00000223496	homo_sapiens	ENSP00000398597	94.8529	93.3824	sus_scrofa	ENSSSCP00000002934	94.8529	93.3824
ENSG00000223496	homo_sapiens	ENSP00000398597	96.3235	96.3235	microcebus_murinus	ENSMICP00000030511	96.3235	96.3235
ENSG00000223496	homo_sapiens	ENSP00000398597	95.9559	94.1176	octodon_degus	ENSODEP00000026947	95.9559	94.1176
ENSG00000223496	homo_sapiens	ENSP00000398597	70.2206	68.3824	jaculus_jaculus	ENSJJAP00000002119	94.5545	92.0792
ENSG00000223496	homo_sapiens	ENSP00000398597	94.8529	94.4853	ovis_aries_rambouillet	ENSOARP00020022117	94.8529	94.4853
ENSG00000223496	homo_sapiens	ENSP00000398597	94.8529	93.0147	delphinapterus_leucas	ENSDLEP00000003779	94.8529	93.0147
ENSG00000223496	homo_sapiens	ENSP00000398597	94.8529	92.6471	physeter_catodon	ENSPCTP00005015909	94.8529	92.6471
ENSG00000223496	homo_sapiens	ENSP00000398597	94.8529	91.9118	mus_musculus	ENSMUSP00000147696	94.5055	91.5751
ENSG00000223496	homo_sapiens	ENSP00000398597	87.8676	87.1324	aotus_nancymaae	ENSANAP00000001061	92.278	91.5058
ENSG00000223496	homo_sapiens	ENSP00000398597	52.5735	52.2059	saimiri_boliviensis_boliviensis	ENSSBOP00000021691	96.6216	95.9459
ENSG00000223496	homo_sapiens	ENSP00000398597	95.5882	93.75	mesocricetus_auratus	ENSMAUP00000005952	95.5882	93.75
ENSG00000223496	homo_sapiens	ENSP00000398597	94.4853	92.6471	phocoena_sinus	ENSPSNP00000025773	94.4853	92.6471
ENSG00000223496	homo_sapiens	ENSP00000398597	94.8529	93.0147	camelus_dromedarius	ENSCDRP00005017502	94.8529	93.0147
ENSG00000223496	homo_sapiens	ENSP00000398597	94.8529	92.2794	rattus_norvegicus	ENSRNOP00000025179	94.8529	92.2794
ENSG00000223496	homo_sapiens	ENSP00000398597	96.3235	96.3235	prolemur_simus	ENSPSMP00000021142	96.3235	96.3235
ENSG00000223496	homo_sapiens	ENSP00000398597	94.8529	93.0147	microtus_ochrogaster	ENSMOCP00000003769	94.8529	93.0147
ENSG00000223496	homo_sapiens	ENSP00000398597	94.8529	91.9118	mus_spicilegus	ENSMSIP00000022834	94.5055	91.5751
ENSG00000223496	homo_sapiens	ENSP00000398597	95.5882	93.3824	cricetulus_griseus_chok1gshd	ENSCGRP00001001166	95.5882	93.3824
ENSG00000223496	homo_sapiens	ENSP00000398597	95.5882	94.8529	pteropus_vampyrus	ENSPVAP00000000630	95.5882	94.8529
ENSG00000223496	homo_sapiens	ENSP00000398597	52.9412	50	myotis_lucifugus	ENSMLUP00000017489	83.7209	79.0698
ENSG00000223496	homo_sapiens	ENSP00000398597	70.5882	61.7647	vombatus_ursinus	ENSVURP00010021383	69.8182	61.0909
ENSG00000223496	homo_sapiens	ENSP00000398597	94.4853	92.6471	rhinolophus_ferrumequinum	ENSRFEP00010019025	94.4853	92.6471
ENSG00000223496	homo_sapiens	ENSP00000398597	94.1176	93.0147	bos_taurus	ENSBTAP00000073635	94.1176	93.0147
ENSG00000223496	homo_sapiens	ENSP00000398597	94.4853	92.6471	heterocephalus_glaber_female	ENSHGLP00000028899	94.4853	92.6471
ENSG00000223496	homo_sapiens	ENSP00000398597	88.6029	88.2353	rhinopithecus_bieti	ENSRBIP00000000638	88.6029	88.2353
ENSG00000223496	homo_sapiens	ENSP00000398597	95.5882	95.2206	canis_lupus_dingo	ENSCAFP00020026684	95.5882	95.2206
ENSG00000223496	homo_sapiens	ENSP00000398597	95.9559	94.1176	sciurus_vulgaris	ENSSVLP00005026034	95.9559	94.1176
ENSG00000223496	homo_sapiens	ENSP00000398597	84.5588	81.9853	phascolarctos_cinereus	ENSPCIP00000013587	53.2407	51.6204
ENSG00000223496	homo_sapiens	ENSP00000398597	71.6912	60.2941	phascolarctos_cinereus	ENSPCIP00000007437	57.1847	48.0938
ENSG00000223496	homo_sapiens	ENSP00000398597	94.4853	92.6471	procavia_capensis	ENSPCAP00000011979	94.4853	92.6471
ENSG00000223496	homo_sapiens	ENSP00000398597	64.3382	63.9706	chinchilla_lanigera	ENSCLAP00000005811	94.5946	94.0541
ENSG00000223496	homo_sapiens	ENSP00000398597	81.6176	80.1471	cervus_hanglu_yarkandensis	ENSCHYP00000029845	87.0588	85.4902
ENSG00000223496	homo_sapiens	ENSP00000398597	94.4853	93.0147	catagonus_wagneri	ENSCWAP00000002241	94.4853	93.0147
ENSG00000223496	homo_sapiens	ENSP00000398597	96.3235	93.3824	ictidomys_tridecemlineatus	ENSSTOP00000022809	96.3235	93.3824
ENSG00000223496	homo_sapiens	ENSP00000398597	97.0588	96.3235	otolemur_garnettii	ENSOGAP00000018988	97.0588	96.3235
ENSG00000223496	homo_sapiens	ENSP00000398597	96.3235	93.75	urocitellus_parryii	ENSUPAP00010019139	96.3235	93.75
ENSG00000223496	homo_sapiens	ENSP00000398597	94.1176	93.75	moschus_moschiferus	ENSMMSP00000023442	94.1176	93.75
ENSG00000223496	homo_sapiens	ENSP00000398597	38.9706	22.4265	caenorhabditis_elegans	Y6D11A.1.1	43.9834	25.3112
ENSG00000223496	homo_sapiens	ENSP00000398597	41.5441	25	drosophila_melanogaster	FBpp0074687	34.6626	20.8589
ENSG00000223496	homo_sapiens	ENSP00000398597	55.5147	34.5588	ciona_intestinalis	ENSCINP00000024693	53.9286	33.5714
ENSG00000223496	homo_sapiens	ENSP00000398597	38.2353	27.5735	callorhinchus_milii	ENSCMIP00000004830	56.2162	40.5405
ENSG00000223496	homo_sapiens	ENSP00000398597	63.9706	48.1618	lepisosteus_oculatus	ENSLOCP00000021702	63.2727	47.6364
ENSG00000223496	homo_sapiens	ENSP00000398597	61.3971	44.8529	clupea_harengus	ENSCHAP00000001778	60.7273	44.3636
ENSG00000223496	homo_sapiens	ENSP00000398597	64.3382	46.3235	danio_rerio	ENSDARP00000052347	64.5756	46.4945
ENSG00000223496	homo_sapiens	ENSP00000398597	64.3382	47.4265	carassius_auratus	ENSCARP00000013926	62.0567	45.7447
ENSG00000223496	homo_sapiens	ENSP00000398597	63.9706	47.0588	astyanax_mexicanus	ENSAMXP00000026974	64.2066	47.2325
ENSG00000223496	homo_sapiens	ENSP00000398597	63.2353	46.6912	ictalurus_punctatus	ENSIPUP00000006871	63.7037	47.037
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	45.9559	esox_lucius	ENSELUP00000036259	60.6498	45.1264
ENSG00000223496	homo_sapiens	ENSP00000398597	64.7059	46.6912	electrophorus_electricus	ENSEEEP00000034808	64.9446	46.8635
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	45.5882	oncorhynchus_kisutch	ENSOKIP00005051472	60.6498	44.7653
ENSG00000223496	homo_sapiens	ENSP00000398597	61.3971	45.2206	oncorhynchus_mykiss	ENSOMYP00000043014	60.2888	44.4043
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	45.5882	salmo_salar	ENSSSAP00000182817	60.6498	44.7653
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	45.5882	salmo_trutta	ENSSTUP00000029514	60.6498	44.7653
ENSG00000223496	homo_sapiens	ENSP00000398597	62.1324	45.2206	gadus_morhua	ENSGMOP00000008722	61.6788	44.8905
ENSG00000223496	homo_sapiens	ENSP00000398597	63.2353	47.4265	fundulus_heteroclitus	ENSFHEP00000031536	62.3188	46.7391
ENSG00000223496	homo_sapiens	ENSP00000398597	62.5	45.9559	poecilia_reticulata	ENSPREP00000028899	62.0438	45.6204
ENSG00000223496	homo_sapiens	ENSP00000398597	62.5	46.3235	xiphophorus_maculatus	ENSXMAP00000006296	62.0438	45.9854
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	45.5882	oryzias_latipes	ENSORLP00000016702	61.7647	45.5882
ENSG00000223496	homo_sapiens	ENSP00000398597	63.2353	46.3235	cyclopterus_lumpus	ENSCLMP00005021338	63.7037	46.6667
ENSG00000223496	homo_sapiens	ENSP00000398597	62.1324	43.75	oreochromis_niloticus	ENSONIP00000055029	53.6508	37.7778
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	43.75	haplochromis_burtoni	ENSHBUP00000009595	61.3139	43.4307
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	43.75	astatotilapia_calliptera	ENSACLP00000032888	61.3139	43.4307
ENSG00000223496	homo_sapiens	ENSP00000398597	62.5	45.5882	sparus_aurata	ENSSAUP00010024153	54.6624	39.8714
ENSG00000223496	homo_sapiens	ENSP00000398597	62.1324	45.2206	lates_calcarifer	ENSLCAP00010025716	64.751	47.1264
ENSG00000223496	homo_sapiens	ENSP00000398597	37.1324	27.2059	xenopus_tropicalis	ENSXETP00000112727	46.3303	33.945
ENSG00000223496	homo_sapiens	ENSP00000398597	39.7059	29.7794	xenopus_tropicalis	ENSXETP00000080162	52.1739	39.1304
ENSG00000223496	homo_sapiens	ENSP00000398597	35.2941	26.8382	xenopus_tropicalis	ENSXETP00000093073	46.8293	35.6098
ENSG00000223496	homo_sapiens	ENSP00000398597	40.0735	29.7794	xenopus_tropicalis	ENSXETP00000078755	49.3213	36.6516
ENSG00000223496	homo_sapiens	ENSP00000398597	40.8088	27.5735	xenopus_tropicalis	ENSXETP00000116641	46.0581	31.1203
ENSG00000223496	homo_sapiens	ENSP00000398597	65.8088	55.5147	xenopus_tropicalis	ENSXETP00000016677	66.2963	55.9259
ENSG00000223496	homo_sapiens	ENSP00000398597	41.9118	30.8824	xenopus_tropicalis	ENSXETP00000111479	51.1211	37.6682
ENSG00000223496	homo_sapiens	ENSP00000398597	37.1324	27.2059	xenopus_tropicalis	ENSXETP00000081864	60.479	44.3114
ENSG00000223496	homo_sapiens	ENSP00000398597	76.1029	65.4412	laticauda_laticaudata	ENSLLTP00000007155	72.8873	62.6761
ENSG00000223496	homo_sapiens	ENSP00000398597	77.9412	67.6471	notechis_scutatus	ENSNSUP00000017587	73.1034	63.4483
ENSG00000223496	homo_sapiens	ENSP00000398597	77.2059	66.9118	pseudonaja_textilis	ENSPTXP00000011618	72.9167	63.1944
ENSG00000223496	homo_sapiens	ENSP00000398597	77.2059	66.9118	pseudonaja_textilis	ENSPTXP00000026278	72.9167	63.1944
ENSG00000223496	homo_sapiens	ENSP00000398597	74.2647	63.6029	anas_platyrhynchos_platyrhynchos	ENSAPLP00000025427	70.3833	60.2787
ENSG00000223496	homo_sapiens	ENSP00000398597	71.6912	62.8676	gallus_gallus	ENSGALP00010038384	69.8925	61.2903
ENSG00000223496	homo_sapiens	ENSP00000398597	73.1618	63.9706	parus_major	ENSPMJP00000018965	72.3636	63.2727
ENSG00000223496	homo_sapiens	ENSP00000398597	66.9118	57.7206	anolis_carolinensis	ENSACAP00000024837	69.7318	60.1533
ENSG00000223496	homo_sapiens	ENSP00000398597	62.1324	43.75	neolamprologus_brichardi	ENSNBRP00000009476	61.6788	43.4307
ENSG00000223496	homo_sapiens	ENSP00000398597	76.8382	66.1765	naja_naja	ENSNNAP00000024641	66.3492	57.1429
ENSG00000223496	homo_sapiens	ENSP00000398597	75.3676	66.5441	podarcis_muralis	ENSPMRP00000031457	74.0072	65.343
ENSG00000223496	homo_sapiens	ENSP00000398597	73.5294	64.3382	taeniopygia_guttata	ENSTGUP00000034650	72.9927	63.8686
ENSG00000223496	homo_sapiens	ENSP00000398597	63.2353	46.6912	erpetoichthys_calabaricus	ENSECRP00000018939	63.2353	46.6912
ENSG00000223496	homo_sapiens	ENSP00000398597	62.8676	46.6912	kryptolebias_marmoratus	ENSKMAP00000013067	63.5688	47.2119
ENSG00000223496	homo_sapiens	ENSP00000398597	77.2059	68.75	salvator_merianae	ENSSMRP00000022007	69.3069	61.7162
ENSG00000223496	homo_sapiens	ENSP00000398597	62.5	46.6912	oryzias_javanicus	ENSOJAP00000025820	62.5	46.6912
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	44.8529	amphilophus_citrinellus	ENSACIP00000021416	61.3139	44.5255
ENSG00000223496	homo_sapiens	ENSP00000398597	62.1324	45.2206	dicentrarchus_labrax	ENSDLAP00005023588	61.6788	44.8905
ENSG00000223496	homo_sapiens	ENSP00000398597	61.0294	44.8529	amphiprion_percula	ENSAPEP00000032292	60.5839	44.5255
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	45.2206	oryzias_sinensis	ENSOSIP00000036575	61.7647	45.2206
ENSG00000223496	homo_sapiens	ENSP00000398597	74.6324	66.5441	gopherus_evgoodei	ENSGEVP00005025317	76.8939	68.5606
ENSG00000223496	homo_sapiens	ENSP00000398597	61.3971	44.1176	seriola_dumerili	ENSSDUP00000029303	60.9489	43.7956
ENSG00000223496	homo_sapiens	ENSP00000398597	62.8676	44.8529	cottoperca_gobio	ENSCGOP00000020480	62.4088	44.5255
ENSG00000223496	homo_sapiens	ENSP00000398597	74.2647	64.7059	anser_brachyrhynchus	ENSABRP00000004185	72.6619	63.3094
ENSG00000223496	homo_sapiens	ENSP00000398597	64.7059	46.6912	gasterosteus_aculeatus	ENSGACP00000003517	64.2336	46.3504
ENSG00000223496	homo_sapiens	ENSP00000398597	56.25	39.3382	cynoglossus_semilaevis	ENSCSEP00000022419	56.6667	39.6296
ENSG00000223496	homo_sapiens	ENSP00000398597	63.2353	47.0588	poecilia_formosa	ENSPFOP00000015922	62.7737	46.7153
ENSG00000223496	homo_sapiens	ENSP00000398597	62.8676	45.5882	myripristis_murdjan	ENSMMDP00005019264	62.4088	45.2555
ENSG00000223496	homo_sapiens	ENSP00000398597	62.8676	45.9559	sander_lucioperca	ENSSLUP00000017666	62.4088	45.6204
ENSG00000223496	homo_sapiens	ENSP00000398597	61.3971	44.8529	amphiprion_ocellaris	ENSAOCP00000003647	60.9489	44.5255
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	45.9559	hucho_hucho	ENSHHUP00000061755	60.6498	45.1264
ENSG00000223496	homo_sapiens	ENSP00000398597	61.3971	43.0147	betta_splendens	ENSBSLP00000002902	61.1722	42.8571
ENSG00000223496	homo_sapiens	ENSP00000398597	64.7059	45.5882	pygocentrus_nattereri	ENSPNAP00000001938	64.9446	45.7565
ENSG00000223496	homo_sapiens	ENSP00000398597	62.1324	44.8529	anabas_testudineus	ENSATEP00000020297	61.9048	44.6886
ENSG00000223496	homo_sapiens	ENSP00000398597	53.3088	34.1912	ciona_savignyi	ENSCSAVP00000004333	53.7037	34.4444
ENSG00000223496	homo_sapiens	ENSP00000398597	29.7794	18.3824	saccharomyces_cerevisiae	YGR158C	32.4	20
ENSG00000223496	homo_sapiens	ENSP00000398597	62.5	44.8529	seriola_lalandi_dorsalis	ENSSLDP00000022776	61.1511	43.8849
ENSG00000223496	homo_sapiens	ENSP00000398597	62.5	44.4853	labrus_bergylta	ENSLBEP00000024376	53.4591	38.0503
ENSG00000223496	homo_sapiens	ENSP00000398597	62.1324	43.75	pundamilia_nyererei	ENSPNYP00000014197	61.6788	43.4307
ENSG00000223496	homo_sapiens	ENSP00000398597	61.0294	45.2206	mastacembelus_armatus	ENSMAMP00000042128	60.5839	44.8905
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	44.8529	stegastes_partitus	ENSSPAP00000001780	61.3139	44.5255
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	45.5882	oncorhynchus_tshawytscha	ENSOTSP00005015302	60.6498	44.7653
ENSG00000223496	homo_sapiens	ENSP00000398597	61.0294	44.4853	acanthochromis_polyacanthus	ENSAPOP00000033658	60.5839	44.1606
ENSG00000223496	homo_sapiens	ENSP00000398597	73.8971	63.6029	aquila_chrysaetos_chrysaetos	ENSACCP00020004884	71.5303	61.5658
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	45.2206	nothobranchius_furzeri	ENSNFUP00015047382	61.7647	45.2206
ENSG00000223496	homo_sapiens	ENSP00000398597	45.2206	32.3529	cyprinodon_variegatus	ENSCVAP00000031612	61.809	44.2211
ENSG00000223496	homo_sapiens	ENSP00000398597	45.5882	32.7206	cyprinodon_variegatus	ENSCVAP00000031624	61.6915	44.2786
ENSG00000223496	homo_sapiens	ENSP00000398597	63.9706	47.7941	denticeps_clupeoides	ENSDCDP00000036341	63.5037	47.4453
ENSG00000223496	homo_sapiens	ENSP00000398597	62.1324	45.2206	larimichthys_crocea	ENSLCRP00005063367	61.4545	44.7273
ENSG00000223496	homo_sapiens	ENSP00000398597	60.2941	44.8529	takifugu_rubripes	ENSTRUP00000067574	59.854	44.5255
ENSG00000223496	homo_sapiens	ENSP00000398597	62.1324	45.5882	hippocampus_comes	ENSHCOP00000009646	61.6788	45.2555
ENSG00000223496	homo_sapiens	ENSP00000398597	65.4412	48.8971	cyprinus_carpio_carpio	ENSCCRP00000113071	65.9259	49.2593
ENSG00000223496	homo_sapiens	ENSP00000398597	64.7059	48.1618	cyprinus_carpio_carpio	ENSCCRP00000144013	65.1852	48.5185
ENSG00000223496	homo_sapiens	ENSP00000398597	71.6912	62.1324	coturnix_japonica	ENSCJPP00005013429	70.6522	61.2319
ENSG00000223496	homo_sapiens	ENSP00000398597	63.2353	46.6912	poecilia_latipinna	ENSPLAP00000011109	62.7737	46.3504
ENSG00000223496	homo_sapiens	ENSP00000398597	64.3382	48.1618	sinocyclocheilus_grahami	ENSSGRP00000055939	64.8148	48.5185
ENSG00000223496	homo_sapiens	ENSP00000398597	64.3382	48.5294	sinocyclocheilus_grahami	ENSSGRP00000041298	64.8148	48.8889
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	43.75	maylandia_zebra	ENSMZEP00005014235	61.3139	43.4307
ENSG00000223496	homo_sapiens	ENSP00000398597	59.9265	45.5882	tetraodon_nigroviridis	ENSTNIP00000006627	65.7258	50
ENSG00000223496	homo_sapiens	ENSP00000398597	65.4412	50	paramormyrops_kingsleyae	ENSPKIP00000005292	65.6827	50.1845
ENSG00000223496	homo_sapiens	ENSP00000398597	64.3382	52.2059	scleropages_formosus	ENSSFOP00015070849	61.8375	50.1767
ENSG00000223496	homo_sapiens	ENSP00000398597	59.9265	49.6324	leptobrachium_leishanense	ENSLLEP00000048059	67.6349	56.0166
ENSG00000223496	homo_sapiens	ENSP00000398597	61.7647	43.75	scophthalmus_maximus	ENSSMAP00000023835	61.0909	43.2727
ENSG00000223496	homo_sapiens	ENSP00000398597	62.1324	45.2206	oryzias_melastigma	ENSOMEP00000012886	62.8253	45.7249

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000176	part_of nuclear exosome (RNase complex)	2	IBA,NAS	Homo_sapiens(9606)	Component
GO:0000177	part_of cytoplasmic exosome (RNase complex)	2	IBA,NAS	Homo_sapiens(9606)	Component
GO:0000178	part_of exosome (RNase complex)	2	IDA,NAS	Homo_sapiens(9606)	Component
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0004532	NOT enables RNA exonuclease activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0005730	is_active_in nucleolus	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0006364	involved_in rRNA processing	1	IEA	Homo_sapiens(9606)	Process
GO:0006396	involved_in RNA processing	1	IDA	Homo_sapiens(9606)	Process
GO:0006401	involved_in RNA catabolic process	1	IDA	Homo_sapiens(9606)	Process
GO:0016075	involved_in rRNA catabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0034427	involved_in nuclear-transcribed mRNA catabolic process, exonucleolytic, 3-5	1	IBA	Homo_sapiens(9606)	Process
GO:0034475	involved_in U4 snRNA 3-end processing	1	IBA	Homo_sapiens(9606)	Process
GO:0045006	involved_in DNA deamination	1	IDA	Homo_sapiens(9606)	Process
GO:0045190	involved_in isotype switching	1	ISS	Homo_sapiens(9606)	Process
GO:0045830	involved_in positive regulation of isotype switching	1	IEA	Homo_sapiens(9606)	Process
GO:0071028	involved_in nuclear mRNA surveillance	1	IBA	Homo_sapiens(9606)	Process
GO:0071051	involved_in polyadenylation-dependent snoRNA 3-end processing	1	IBA	Homo_sapiens(9606)	Process
GO:0101019	part_of nucleolar exosome (RNase complex)	1	NAS	Homo_sapiens(9606)	Component