RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	Drug
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000213619	Gene ID	4722	Accession	7710
Symbol	NDUFS3	Alias	CI-30;MC1DN8	Full Name	NADH:ubiquinone oxidoreductase core subunit S3
Status	Confidence	Length	5534 bases	Strand	Plus strand
Position	11 : 47579029 - 47584562	RNA binding domain	N.A.
Summary	This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
NDUFS3-211	ENST00000533507	1769	No protein	-
NDUFS3-207	ENST00000529276	558	67aa	ENSP00000433753
NDUFS3-206	ENST00000528192	561	161aa	ENSP00000432099
NDUFS3-208	ENST00000530295	253	77aa	ENSP00000431588
NDUFS3-212	ENST00000534208	583	121aa	ENSP00000433405
NDUFS3-213	ENST00000534716	1263	No protein	-
NDUFS3-201	ENST00000263774	894	264aa	ENSP00000263774
NDUFS3-210	ENST00000533105	567	No protein	-
NDUFS3-202	ENST00000524568	733	No protein	-
NDUFS3-214	ENST00000677462	3333	No protein	-
NDUFS3-215	ENST00000678975	3120	No protein	-
NDUFS3-209	ENST00000531351	2049	No protein	-
NDUFS3-204	ENST00000525378	779	No protein	-
NDUFS3-203	ENST00000525212	530	No protein	-
NDUFS3-205	ENST00000527178	269	No protein	-

Gene Model

Click here to download ENSG00000213619's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000213619's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003954	enables NADH dehydrogenase activity	1	IMP	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005739	located_in mitochondrion	2	IDA,NAS	Homo_sapiens(9606)	Component
GO:0005743	located_in mitochondrial inner membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0005747	part_of mitochondrial respiratory chain complex I	4	IBA,IDA,IPI,NAS	Homo_sapiens(9606)	Component
GO:0005759	located_in mitochondrial matrix	1	TAS	Homo_sapiens(9606)	Component
GO:0006120	involved_in mitochondrial electron transport, NADH to ubiquinone	2	IMP,NAS	Homo_sapiens(9606)	Process
GO:0008137	contributes_to NADH dehydrogenase (ubiquinone) activity	3	IMP,NAS	Homo_sapiens(9606)	Function
GO:0009055	enables electron transfer activity	1	NAS	Homo_sapiens(9606)	Function
GO:0009060	involved_in aerobic respiration	1	NAS	Homo_sapiens(9606)	Process
GO:0016604	located_in nuclear body	1	IDA	Homo_sapiens(9606)	Component
GO:0021762	involved_in substantia nigra development	1	HEP	Homo_sapiens(9606)	Process
GO:0030308	involved_in negative regulation of cell growth	1	IMP	Homo_sapiens(9606)	Process
GO:0031966	located_in mitochondrial membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0032981	involved_in mitochondrial respiratory chain complex I assembly	1	IMP	Homo_sapiens(9606)	Process
GO:0042776	involved_in proton motive force-driven mitochondrial ATP synthesis	1	NAS	Homo_sapiens(9606)	Process
GO:0072593	involved_in reactive oxygen species metabolic process	1	IMP	Homo_sapiens(9606)	Process
GO:2001243	involved_in negative regulation of intrinsic apoptotic signaling pathway	1	IMP	Homo_sapiens(9606)	Process

Expression