Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations P-body
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000213516 Gene ID 494115 Accession 25073
Symbol RBMXL1 Alias RBM1 Full Name RBMX like 1
Status Confidence Length 13505 bases Strand Minus strand
Position 1 : 88979456 - 88992960 RNA binding domain RBM1CTR , RRM_1
Summary This gene represents a retrogene of RNA binding motif protein, X-linked (RBMX), which is located on chromosome X. While all introns in the coding sequence have been processed out compared to the RBMX locus, the ORF is intact and there is specific evidence for transcription at this location. The preservation of the ORF by purifying selection in all Old World monkeys carrying it suggests that this locus is likely to be functional, possibly during male meiosis when X chromosomal genes are silenced or during haploid stages of spermatogenesis. This gene shares 5' exon structure with the cysteine conjugate-beta lyase 2 locus on chromosome 1, but the coding sequences are non-overlapping. Alternative splicing results in two transcript variants. [provided by RefSeq, Jun 2009]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000490152 RRM_1 PF00076 5e-23 1
ENSP00000318415 RRM_1 PF00076 2.6e-22 1
ENSP00000318415 RBM1CTR PF08081 4.7e-22 2
ENSP00000446099 RRM_1 PF00076 2.6e-22 1
ENSP00000446099 RBM1CTR PF08081 4.7e-22 2
ENSP00000498248 RRM_1 PF00076 2.6e-22 1
ENSP00000498248 RBM1CTR PF08081 4.7e-22 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
23704925 Comprehensive genomic characterization of cutaneous malignant melanoma cell lines derived from metastatic lesions by whole-exome sequencing and SNP array profiling. Ingrid Cifola 2013-01-01 PloS one

Transcripts

Name Transcript ID bp Protein Translation ID
RBMXL1-204 ENST00000652648 4756 390aa ENSP00000498248
RBMXL1-201 ENST00000321792 4799 390aa ENSP00000318415
RBMXL1-202 ENST00000399794 5084 390aa ENSP00000446099
RBMXL1-203 ENST00000413769 991 158aa ENSP00000490152

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000213516homo_sapiensENSP0000035964595.907995.1407homo_sapiensENSP0000049824896.153895.3846
ENSG00000213516homo_sapiensENSP0000029597114.16538.76897homo_sapiensENSP0000049824821.538513.3333
ENSG00000213516homo_sapiensENSP0000030413975.510269.1327homo_sapiensENSP0000049824875.897469.4872
ENSG00000213516homo_sapiensENSP0000041745122.774119.3065homo_sapiensENSP0000049824862.307752.8205
ENSG00000213516homo_sapiensENSP0000047869141.642227.8592homo_sapiensENSP0000049824836.410324.359
ENSG00000213516homo_sapiensENSP0000044536615.29759.91501homo_sapiensENSP0000049824813.84628.97436
ENSG00000213516homo_sapiensENSP0000034182641.12925.8065homo_sapiensENSP0000049824839.230824.6154
ENSG00000213516homo_sapiensENSP000003500904528.75homo_sapiensENSP0000049824836.923123.5897
ENSG00000213516homo_sapiensENSP0000049380546.87529.375homo_sapiensENSP0000049824838.461524.1026
ENSG00000213516homo_sapiensENSP0000037630937.566125.9259homo_sapiensENSP0000049824836.410325.1282
ENSG00000213516homo_sapiensENSP0000028407335.670723.7805homo_sapiensENSP000004982483020
ENSG00000213516homo_sapiensENSP0000031047123.676916.7131homo_sapiensENSP0000049824821.794915.3846
ENSG00000213516homo_sapiensENSP0000030916622.527515.6593homo_sapiensENSP0000049824821.025614.6154
ENSG00000213516homo_sapiensENSP0000040137123.834213.9896homo_sapiensENSP0000049824823.589713.8462
ENSG00000213516homo_sapiensENSP0000025755231.76820.9945homo_sapiensENSP0000049824829.487219.4872
ENSG00000213516homo_sapiensENSP0000028172216.51038.81801homo_sapiensENSP0000049824822.564112.0513
ENSG00000213516homo_sapiensENSP0000035295613.66747.74487homo_sapiensENSP0000049824815.38468.71795
ENSG00000213516homo_sapiensENSP0000036293622.299713.2404homo_sapiensENSP0000049824816.41039.74359
ENSG00000213516homo_sapiensENSP0000031319928.450719.1549homo_sapiensENSP0000049824825.897417.4359
ENSG00000213516homo_sapiensENSP0000025336312.83028.11321homo_sapiensENSP0000049824817.435911.0256
ENSG00000213516homo_sapiensENSP0000036310915.69978.87372homo_sapiensENSP0000049824823.589713.3333
ENSG00000213516homo_sapiensENSP0000031604236.721326.5574homo_sapiensENSP0000049824828.717920.7692
ENSG00000213516homo_sapiensENSP0000031819514.08458.16901homo_sapiensENSP0000049824825.64114.8718
ENSG00000213516homo_sapiensENSP0000039490223.466713.3333homo_sapiensENSP0000049824822.564112.8205
ENSG00000213516homo_sapiensENSP0000035110831.024119.8795homo_sapiensENSP0000049824826.410316.9231
ENSG00000213516homo_sapiensENSP0000026174110.72925.3125homo_sapiensENSP0000049824826.410313.0769
ENSG00000213516homo_sapiensENSP0000023307836.117924.57homo_sapiensENSP0000049824837.692325.641
ENSG00000213516homo_sapiensENSP0000037212756.2546.1694homo_sapiensENSP0000049824871.538558.7179
ENSG00000213516homo_sapiensENSP0000037210556.2545.9677homo_sapiensENSP0000049824871.538558.4615
ENSG00000213516homo_sapiensENSP0000037248456.451646.371homo_sapiensENSP0000049824871.794958.9744
ENSG00000213516homo_sapiensENSP0000037215456.048446.1694homo_sapiensENSP0000049824871.282158.7179
ENSG00000213516homo_sapiensENSP0000025083156.2546.371homo_sapiensENSP0000049824871.538558.9744
ENSG00000213516homo_sapiensENSP0000030715556.2546.371homo_sapiensENSP0000049824871.538558.9744
ENSG00000213516homo_sapiensENSP0000029547022.61915homo_sapiensENSP0000049824824.35916.1538
ENSG00000213516homo_sapiensENSP0000046602543.434336.0269homo_sapiensENSP0000049824833.076927.4359
ENSG00000213516homo_sapiensENSP0000036595070.063756.051homo_sapiensENSP0000049824828.205122.5641

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000213516homo_sapiensENSP0000049824869.743666.6667nomascus_leucogenysENSNLEP0000004164780.952477.381
ENSG00000213516homo_sapiensENSP0000049824898.461598.2051pongo_abeliiENSPPYP0000003686974.418674.2248
ENSG00000213516homo_sapiensENSP0000049824882.307780.2564gorilla_gorillaENSGGOP0000004539777.349475.4217
ENSG00000213516homo_sapiensENSP0000049824890.512889.4872gorilla_gorillaENSGGOP0000003369582.476681.5421
ENSG00000213516homo_sapiensENSP0000049824894.871891.5385ornithorhynchus_anatinusENSOANP0000001848788.095285
ENSG00000213516homo_sapiensENSP0000049824893.076988.4615sarcophilus_harrisiiENSSHAP0000002769386.428682.1429
ENSG00000213516homo_sapiensENSP0000049824888.461583.0769sarcophilus_harrisiiENSSHAP0000003061288.917583.5052
ENSG00000213516homo_sapiensENSP0000049824852.307750notamacropus_eugeniiENSMEUP0000001451451.776649.4924
ENSG00000213516homo_sapiensENSP0000049824891.025686.4103notamacropus_eugeniiENSMEUP0000001261490.101585.533
ENSG00000213516homo_sapiensENSP0000049824856.923153.3333dasypus_novemcinctusENSDNOP0000003320974.747570.0337
ENSG00000213516homo_sapiensENSP0000049824872.564167.9487dasypus_novemcinctusENSDNOP0000001691873.697969.0104
ENSG00000213516homo_sapiensENSP000004982488078.7179echinops_telfairiENSETEP0000001068779.591878.3163
ENSG00000213516homo_sapiensENSP0000049824898.717998.2051macaca_fascicularisENSMFAP0000005249898.465597.954
ENSG00000213516homo_sapiensENSP0000049824898.717998.2051macaca_mulattaENSMMUP0000006059998.465597.954
ENSG00000213516homo_sapiensENSP0000049824896.153895.1282papio_anubisENSPANP0000001111095.907994.8849
ENSG00000213516homo_sapiensENSP0000049824858.461556.4103vulpes_vulpesENSVVUP0000001289082.608779.7101
ENSG00000213516homo_sapiensENSP0000049824895.128293.8462capra_hircusENSCHIP0000001146693.92492.6582
ENSG00000213516homo_sapiensENSP000004982484038.2051panthera_leoENSPLOP0000002547784.782680.9783
ENSG00000213516homo_sapiensENSP0000049824876.923174.1026bos_indicus_hybridENSBIXP0000502271379.365176.455
ENSG00000213516homo_sapiensENSP0000049824872.051370.7692oryctolagus_cuniculusENSOCUP0000003791889.776488.1789
ENSG00000213516homo_sapiensENSP0000049824863.076962.0513canis_lupus_familiarisENSCAFP0084503080084.246682.8767
ENSG00000213516homo_sapiensENSP0000049824872.564171.2821balaenoptera_musculusENSBMSP0001000581494.648892.9766
ENSG00000213516homo_sapiensENSP0000049824895.897495.1282cavia_porcellusENSCPOP0000001093795.652294.8849
ENSG00000213516homo_sapiensENSP0000049824893.076988.7179monodelphis_domesticaENSMODP0000005449592.13287.8173
ENSG00000213516homo_sapiensENSP0000049824895.897495.1282bison_bison_bisonENSBBBP0000001595295.652294.8849
ENSG00000213516homo_sapiensENSP0000049824867.179564.8718microcebus_murinusENSMICP0000003795392.907889.7163
ENSG00000213516homo_sapiensENSP0000049824874.615472.3077microcebus_murinusENSMICP0000004171792.38189.5238
ENSG00000213516homo_sapiensENSP0000049824895.897495.1282ovis_aries_rambouilletENSOARP0002002019395.652294.8849
ENSG00000213516homo_sapiensENSP0000049824888.205186.9231ursus_maritimusENSUMAP0000001447395.290993.9058
ENSG00000213516homo_sapiensENSP0000049824895.128293.8462mus_caroliMGP_CAROLIEiJ_P008507695.618694.3299
ENSG00000213516homo_sapiensENSP0000049824895.128293.8462mus_musculusENSMUSP0000004815395.618694.3299
ENSG00000213516homo_sapiensENSP0000049824894.871893.3333mus_musculusENSMUSP0000015463395.360893.8144
ENSG00000213516homo_sapiensENSP0000049824895.897495.1282aotus_nancymaaeENSANAP0000002118395.652294.8849
ENSG00000213516homo_sapiensENSP0000049824888.974485.641saimiri_boliviensis_boliviensisENSSBOP0000001984092.042488.5942
ENSG00000213516homo_sapiensENSP0000049824895.384694.1026mesocricetus_auratusENSMAUP0000001793395.876394.5876
ENSG00000213516homo_sapiensENSP0000049824896.153895.1282carlito_syrichtaENSTSYP0000003405895.907994.8849
ENSG00000213516homo_sapiensENSP0000049824868.717968.2051panthera_tigris_altaicaENSPTIP0000002594694.699693.9929
ENSG00000213516homo_sapiensENSP0000049824895.128293.5897rattus_norvegicusENSRNOP0000007950595.618694.0722
ENSG00000213516homo_sapiensENSP0000049824893.076991.5385rattus_norvegicusENSRNOP0000007464692.60291.0714
ENSG00000213516homo_sapiensENSP0000049824872.307769.7436prolemur_simusENSPSMP0000002928989.808986.6242
ENSG00000213516homo_sapiensENSP0000049824894.871893.5897microtus_ochrogasterENSMOCP0000001928595.360894.0722
ENSG00000213516homo_sapiensENSP0000049824877.435976.6667sorex_araneusENSSARP0000000036095.268194.3218
ENSG00000213516homo_sapiensENSP0000049824895.384694.1026peromyscus_maniculatus_bairdiiENSPEMP0000000402495.876394.5876
ENSG00000213516homo_sapiensENSP0000049824895.897495.1282bos_mutusENSBMUP0000000929395.652294.8849
ENSG00000213516homo_sapiensENSP0000049824895.128293.8462mus_spicilegusENSMSIP0000003526395.618694.3299
ENSG00000213516homo_sapiensENSP0000049824869.487265.1282cricetulus_griseus_chok1gshdENSCGRP0000100556180.415475.3709
ENSG00000213516homo_sapiensENSP0000049824895.384694.1026cricetulus_griseus_chok1gshdENSCGRP0000101226795.876394.5876
ENSG00000213516homo_sapiensENSP0000049824889.230883.3333vombatus_ursinusENSVURP0001000041988.775582.9082
ENSG00000213516homo_sapiensENSP0000049824893.076988.4615vombatus_ursinusENSVURP0001002146492.366487.7863
ENSG00000213516homo_sapiensENSP0000049824895.897495.1282bos_taurusENSBTAP0000001769695.652294.8849
ENSG00000213516homo_sapiensENSP0000049824894.35993.3333heterocephalus_glaber_femaleENSHGLP0000004931094.117693.0946
ENSG00000213516homo_sapiensENSP0000049824895.64194.8718heterocephalus_glaber_femaleENSHGLP0000001546195.396494.6292
ENSG00000213516homo_sapiensENSP0000049824837.435934.6154canis_lupus_dingoENSCAFP0002003228766.972561.9266
ENSG00000213516homo_sapiensENSP0000049824895.128293.8462nannospalax_galiliENSNGAP0000001074695.618694.3299
ENSG00000213516homo_sapiensENSP0000049824895.897495.1282bos_grunniensENSBGRP0000002950495.652294.8849
ENSG00000213516homo_sapiensENSP0000049824895.897495.1282chinchilla_lanigeraENSCLAP0000000315095.652294.8849
ENSG00000213516homo_sapiensENSP0000049824895.897495.1282cervus_hanglu_yarkandensisENSCHYP0000002528794.206693.4509
ENSG00000213516homo_sapiensENSP0000049824894.871893.8462otolemur_garnettiiENSOGAP000000070197473.2
ENSG00000213516homo_sapiensENSP0000049824880.512879.2308cebus_imitatorENSCCAP0000003906091.014589.5652
ENSG00000213516homo_sapiensENSP0000049824877.948775.641cebus_imitatorENSCCAP0000001157884.916282.4022
ENSG00000213516homo_sapiensENSP0000049824882.307778.7179urocitellus_parryiiENSUPAP0001001624869.032366.0215
ENSG00000213516homo_sapiensENSP0000049824872.051371.5385moschus_moschiferusENSMMSP0000000199194.612893.9394
ENSG00000213516homo_sapiensENSP0000049824864.871862.0513moschus_moschiferusENSMMSP0000002484284.615480.9365
ENSG00000213516homo_sapiensENSP0000049824871.538571.0256moschus_moschiferusENSMMSP0000000818493.939493.266
ENSG00000213516homo_sapiensENSP0000049824871.025669.4872moschus_moschiferusENSMMSP0000001457992.026690.0332
ENSG00000213516homo_sapiensENSP0000049824892.564191.7949rhinopithecus_roxellanaENSRROP000000353919594.2105
ENSG00000213516homo_sapiensENSP0000049824889.743687.6923rhinopithecus_roxellanaENSRROP0000001620691.863589.7638
ENSG00000213516homo_sapiensENSP0000049824895.128293.8462mus_pahariMGP_PahariEiJ_P005338095.618694.3299
ENSG00000213516homo_sapiensENSP0000049824875.64167.6923callorhinchus_miliiENSCMIP0000002539577.225169.1099
ENSG00000213516homo_sapiensENSP0000049824891.025687.9487chrysemys_picta_belliiENSCPBP0000003769193.175890.0262
ENSG00000213516homo_sapiensENSP0000049824890.512887.4359sphenodon_punctatusENSSPUP0000001903990.05186.9898
ENSG00000213516homo_sapiensENSP0000049824891.025687.6923crocodylus_porosusENSCPRP0000501208487.871384.6535
ENSG00000213516homo_sapiensENSP0000049824889.487285.8974laticauda_laticaudataENSLLTP0000000537491.122787.4674
ENSG00000213516homo_sapiensENSP0000049824889.487285.8974notechis_scutatusENSNSUP0000002250791.122787.4674
ENSG00000213516homo_sapiensENSP0000049824889.743686.1538pseudonaja_textilisENSPTXP0000001941991.383887.7285
ENSG00000213516homo_sapiensENSP0000049824890.512887.4359anas_platyrhynchos_platyrhynchosENSAPLP0000002995391.688388.5714
ENSG00000213516homo_sapiensENSP0000049824890.512887.4359gallus_gallusENSGALP0001002212791.688388.5714
ENSG00000213516homo_sapiensENSP0000049824890.512887.4359meleagris_gallopavoENSMGAP0000000331691.688388.5714
ENSG00000213516homo_sapiensENSP000004982489086.9231serinus_canariaENSSCAP0000000435591.168888.0519
ENSG00000213516homo_sapiensENSP000004982489086.9231parus_majorENSPMJP0000000036491.168888.0519
ENSG00000213516homo_sapiensENSP000004982489086.6667anolis_carolinensisENSACAP0000000942191.168887.7922
ENSG00000213516homo_sapiensENSP0000049824887.692383.8462naja_najaENSNNAP0000002783490.237586.2797
ENSG00000213516homo_sapiensENSP0000049824891.282187.9487podarcis_muralisENSPMRP0000003485083.568180.5164
ENSG00000213516homo_sapiensENSP000004982489086.9231geospiza_fortisENSGFOP0000001775591.168888.0519
ENSG00000213516homo_sapiensENSP000004982489086.9231taeniopygia_guttataENSTGUP0000000220291.168888.0519
ENSG00000213516homo_sapiensENSP0000049824891.025688.2051salvator_merianaeENSSMRP0000001133692.207889.3506
ENSG00000213516homo_sapiensENSP0000049824891.025687.9487pelodiscus_sinensisENSPSIP0000001256091.968988.8601
ENSG00000213516homo_sapiensENSP0000049824891.025687.9487gopherus_evgoodeiENSGEVP0000502381493.175890.0262
ENSG00000213516homo_sapiensENSP0000049824891.025687.9487chelonoidis_abingdoniiENSCABP0000001334693.175890.0262
ENSG00000213516homo_sapiensENSP0000049824890.512887.4359struthio_camelus_australisENSSCUP0000002238689.367186.3291
ENSG00000213516homo_sapiensENSP0000049824890.512887.4359anser_brachyrhynchusENSABRP0000001358883.254780.4245
ENSG00000213516homo_sapiensENSP0000049824890.256486.9231strigops_habroptilaENSSHBP0000502488187.562284.3284
ENSG00000213516homo_sapiensENSP0000049824891.025687.9487terrapene_carolina_triunguisENSTMTP0000003245693.175890.0262
ENSG00000213516homo_sapiensENSP0000049824890.512887.4359aquila_chrysaetos_chrysaetosENSACCP0002002421591.688388.5714
ENSG00000213516homo_sapiensENSP000004982489086.9231ficedula_albicollisENSFALP0000000392291.168888.0519
ENSG00000213516homo_sapiensENSP0000049824890.512887.4359coturnix_japonicaENSCJPP0000502031191.688388.5714
ENSG00000213516homo_sapiensENSP0000049824881.538575.8974leptobrachium_leishanenseENSLLEP0000002057482.383476.6839

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003723enables RNA binding1IBAHomo_sapiens(9606)Function
GO:0005681part_of spliceosomal complex1IBAHomo_sapiens(9606)Component
GO:0006397involved_in mRNA processing1IEAHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1IEAHomo_sapiens(9606)Process
GO:0048026involved_in positive regulation of mRNA splicing, via spliceosome1IBAHomo_sapiens(9606)Process

Expression