Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000204764 Gene ID 64901 Accession 14428
Symbol RANBP17 Alias NA Full Name RAN binding protein 17
Status Confidence Length 438084 bases Strand Plus strand
Position 5 : 170861932 - 171300015 RNA binding domain IBN_N
Summary The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000427975 IBN_N PF03810 6.8e-10 1
ENSP00000429845 IBN_N PF03810 8e-10 1
ENSP00000373770 IBN_N PF03810 8.3e-10 1
ENSP00000429298 IBN_N PF03810 8.3e-10 1
ENSP00000430444 IBN_N PF03810 8.3e-10 1
ENSP00000430599 IBN_N PF03810 8.3e-10 1
ENSP00000430958 IBN_N PF03810 8.5e-10 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
34262674 Epigenetic reprogramming enhances the therapeutic efficacy of osteoblast-derived extracellular vesicles to promote human bone marrow stem cell osteogenic differentiation. Kenny Man 2021-07-01 Journal of extracellular vesicles

Transcripts

Name Transcript ID bp Protein Translation ID
RANBP17-202 ENST00000443155 1199 No protein -
RANBP17-219 ENST00000523189 4440 1088aa ENSP00000427975
RANBP17-201 ENST00000389118 3653 576aa ENSP00000373770
RANBP17-206 ENST00000519256 3375 576aa ENSP00000429298
RANBP17-217 ENST00000522533 4558 576aa ENSP00000430599
RANBP17-215 ENST00000522066 4739 580aa ENSP00000430958
RANBP17-208 ENST00000519949 4618 576aa ENSP00000430444
RANBP17-205 ENST00000519130 2182 No protein -
RANBP17-210 ENST00000520864 4573 554aa ENSP00000429845
RANBP17-207 ENST00000519944 542 38aa ENSP00000429609
RANBP17-221 ENST00000523727 414 No protein -
RANBP17-218 ENST00000522734 525 175aa ENSP00000430577
RANBP17-211 ENST00000520879 737 No protein -
RANBP17-216 ENST00000522380 766 No protein -
RANBP17-203 ENST00000517629 375 No protein -
RANBP17-212 ENST00000521165 347 No protein -
RANBP17-204 ENST00000518492 296 47aa ENSP00000427980
RANBP17-213 ENST00000521759 1933 No protein -
RANBP17-209 ENST00000520586 604 No protein -
RANBP17-220 ENST00000523665 560 No protein -
RANBP17-222 ENST00000524364 721 No protein -
RANBP17-214 ENST00000521834 885 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
15294Heart Failure7.2253434E-006-
95972Adipose Tissue5E-622589738

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000204764homo_sapiensENSP0000025251282.888767.0653homo_sapiensENSP0000042797582.812567.0037
ENSG00000204764homo_sapiensENSP0000025530537.619519.2876homo_sapiensENSP0000042797539.797820.4044

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000204764homo_sapiensENSP0000042797598.897198.5294nomascus_leucogenysENSNLEP0000000035598.897198.5294
ENSG00000204764homo_sapiensENSP0000042797599.356699.3566pan_paniscusENSPPAP0000003773299.356699.3566
ENSG00000204764homo_sapiensENSP0000042797598.98998.4375pongo_abeliiENSPPYP0000001794798.98998.4375
ENSG00000204764homo_sapiensENSP0000042797599.448599.4485pan_troglodytesENSPTRP0000004785499.448599.4485
ENSG00000204764homo_sapiensENSP0000042797599.448599.2647gorilla_gorillaENSGGOP0000005190599.448599.2647
ENSG00000204764homo_sapiensENSP0000042797595.036889.614ornithorhynchus_anatinusENSOANP0000001241795.036889.614
ENSG00000204764homo_sapiensENSP0000042797595.772189.614sarcophilus_harrisiiENSSHAP0000000037895.772189.614
ENSG00000204764homo_sapiensENSP0000042797568.290463.4191notamacropus_eugeniiENSMEUP0000001509869.439364.486
ENSG00000204764homo_sapiensENSP0000042797577.941275.7353choloepus_hoffmanniENSCHOP0000001032077.941275.7353
ENSG00000204764homo_sapiensENSP0000042797598.069995.0368dasypus_novemcinctusENSDNOP0000000863797.621294.602
ENSG00000204764homo_sapiensENSP0000042797582.904479.2279erinaceus_europaeusENSEEUP0000000522582.525278.8655
ENSG00000204764homo_sapiensENSP0000042797575.275771.2316echinops_telfairiENSETEP0000000840875.275771.2316
ENSG00000204764homo_sapiensENSP0000042797594.577292.5551callithrix_jacchusENSCJAP0000003604298.18796.0878
ENSG00000204764homo_sapiensENSP0000042797599.448598.4375cercocebus_atysENSCATP0000000283699.448598.4375
ENSG00000204764homo_sapiensENSP0000042797596.047894.761macaca_fascicularisENSMFAP0000003595299.334698.0038
ENSG00000204764homo_sapiensENSP0000042797599.264797.7941macaca_mulattaENSMMUP0000003372899.264797.7941
ENSG00000204764homo_sapiensENSP0000042797599.264797.9779macaca_nemestrinaENSMNEP0000004619299.264797.9779
ENSG00000204764homo_sapiensENSP0000042797599.356698.3456papio_anubisENSPANP0000000713799.356698.3456
ENSG00000204764homo_sapiensENSP0000042797546.783145.5882mandrillus_leucophaeusENSMLEP0000001350994.609792.1933
ENSG00000204764homo_sapiensENSP0000042797582.444980.239tursiops_truncatusENSTTRP0000000792682.444980.239
ENSG00000204764homo_sapiensENSP0000042797598.253795.7721vulpes_vulpesENSVVUP0000000342893.525891.1636
ENSG00000204764homo_sapiensENSP0000042797545.588242.9228mus_spretusMGP_SPRETEiJ_P002747396.12490.5039
ENSG00000204764homo_sapiensENSP0000042797598.345695.9559equus_asinusENSEASP0000501700598.345695.9559
ENSG00000204764homo_sapiensENSP0000042797551.378749.7243capra_hircusENSCHIP0000000339696.880493.7608
ENSG00000204764homo_sapiensENSP0000042797597.426594.6691loxodonta_africanaENSLAFP0000000560797.516194.7562
ENSG00000204764homo_sapiensENSP0000042797598.713297.0588panthera_leoENSPLOP0000001689098.713297.0588
ENSG00000204764homo_sapiensENSP0000042797591.819990.1654ailuropoda_melanoleucaENSAMEP0000000418598.326896.5551
ENSG00000204764homo_sapiensENSP0000042797597.518495.3125bos_indicus_hybridENSBIXP0000501596095.931393.7613
ENSG00000204764homo_sapiensENSP0000042797598.345696.0478oryctolagus_cuniculusENSOCUP0000000956296.570494.3141
ENSG00000204764homo_sapiensENSP0000042797598.345695.9559equus_caballusENSECAP0000004107296.570494.2238
ENSG00000204764homo_sapiensENSP0000042797598.345696.3235canis_lupus_familiarisENSCAFP0084500282796.570494.5848
ENSG00000204764homo_sapiensENSP0000042797598.713297.0588panthera_pardusENSPPRP0000002747898.713297.0588
ENSG00000204764homo_sapiensENSP0000042797597.88695.9559marmota_marmota_marmotaENSMMMP0000001172898.428896.488
ENSG00000204764homo_sapiensENSP0000042797598.713296.2316balaenoptera_musculusENSBMSP0001001477598.351695.8791
ENSG00000204764homo_sapiensENSP0000042797597.610393.6581cavia_porcellusENSCPOP0000002400295.848491.9675
ENSG00000204764homo_sapiensENSP0000042797598.713296.9669felis_catusENSFCAP0000002157488.395186.8313
ENSG00000204764homo_sapiensENSP0000042797548.621347.4265ursus_americanusENSUAMP0000002606894.633392.3077
ENSG00000204764homo_sapiensENSP0000042797594.117687.0404monodelphis_domesticaENSMODP0000004049694.902787.7664
ENSG00000204764homo_sapiensENSP0000042797551.01148.5294bison_bison_bisonENSBBBP0000001664090.538386.1338
ENSG00000204764homo_sapiensENSP0000042797598.805196.4154monodon_monocerosENSMMNP0001500940098.805196.4154
ENSG00000204764homo_sapiensENSP0000042797598.621396.3235sus_scrofaENSSSCP0000001801298.621396.3235
ENSG00000204764homo_sapiensENSP0000042797598.345696.5074microcebus_murinusENSMICP0000004834998.345696.5074
ENSG00000204764homo_sapiensENSP0000042797545.86444.3934octodon_degusENSODEP0000000601697.081793.9689
ENSG00000204764homo_sapiensENSP0000042797518.7517.8309octodon_degusENSODEP0000000619997.142992.381
ENSG00000204764homo_sapiensENSP0000042797596.323591.4522jaculus_jaculusENSJJAP0000000251096.323591.4522
ENSG00000204764homo_sapiensENSP0000042797592.187589.1544ovis_aries_rambouilletENSOARP0002002110394.266991.1654
ENSG00000204764homo_sapiensENSP0000042797598.529496.5993ursus_maritimusENSUMAP0000003427497.101495.1993
ENSG00000204764homo_sapiensENSP0000042797569.76167.0956ochotona_princepsENSOPRP0000001401272.980870.1923
ENSG00000204764homo_sapiensENSP0000042797598.897196.4154delphinapterus_leucasENSDLEP0000001597797.111994.6751
ENSG00000204764homo_sapiensENSP0000042797598.529496.2316physeter_catodonENSPCTP0000500316796.750994.4946
ENSG00000204764homo_sapiensENSP0000042797597.242693.2904mus_caroliMGP_CAROLIEiJ_P002612097.242693.2904
ENSG00000204764homo_sapiensENSP0000042797597.518493.75mus_musculusENSMUSP0000009987997.518493.75
ENSG00000204764homo_sapiensENSP0000042797596.599393.8419dipodomys_ordiiENSDORP0000000132396.866494.1014
ENSG00000204764homo_sapiensENSP0000042797598.529496.4154mustela_putorius_furoENSMPUP0000001277696.750994.6751
ENSG00000204764homo_sapiensENSP0000042797598.161896.5074aotus_nancymaaeENSANAP0000002077798.342596.6851
ENSG00000204764homo_sapiensENSP0000042797597.88696.0478saimiri_boliviensis_boliviensisENSSBOP0000003193298.428896.5804
ENSG00000204764homo_sapiensENSP0000042797587.224384.8346vicugna_pacosENSVPAP0000000226187.870485.463
ENSG00000204764homo_sapiensENSP0000042797598.253796.875chlorocebus_sabaeusENSCSAP0000000598398.434697.0534
ENSG00000204764homo_sapiensENSP0000042797596.231693.1985tupaia_belangeriENSTBEP0000000687197.124394.0631
ENSG00000204764homo_sapiensENSP0000042797594.577291.2684mesocricetus_auratusENSMAUP0000001981997.720894.302
ENSG00000204764homo_sapiensENSP0000042797598.621396.3235phocoena_sinusENSPSNP0000001075298.621396.3235
ENSG00000204764homo_sapiensENSP0000042797597.702295.3125camelus_dromedariusENSCDRP0000500844198.334995.9297
ENSG00000204764homo_sapiensENSP0000042797551.562550.2757carlito_syrichtaENSTSYP0000003314296.391893.9863
ENSG00000204764homo_sapiensENSP0000042797598.161896.5074panthera_tigris_altaicaENSPTIP0000002602298.161896.5074
ENSG00000204764homo_sapiensENSP0000042797597.702294.3015rattus_norvegicusENSRNOP0000005664097.702294.3015
ENSG00000204764homo_sapiensENSP0000042797598.345696.2316prolemur_simusENSPSMP0000002406097.184495.0954
ENSG00000204764homo_sapiensENSP0000042797593.106689.614microtus_ochrogasterENSMOCP0000000733697.591593.9306
ENSG00000204764homo_sapiensENSP0000042797582.26176.5625sorex_araneusENSSARP0000000730988.966282.8032
ENSG00000204764homo_sapiensENSP0000042797597.518494.0257peromyscus_maniculatus_bairdiiENSPEMP0000001290897.518494.0257
ENSG00000204764homo_sapiensENSP0000042797545.220643.2904bos_mutusENSBMUP0000003277194.980790.9266
ENSG00000204764homo_sapiensENSP0000042797597.334693.5662mus_spicilegusENSMSIP0000002770095.577691.8773
ENSG00000204764homo_sapiensENSP0000042797597.426593.75cricetulus_griseus_chok1gshdENSCGRP0000101463295.667992.0578
ENSG00000204764homo_sapiensENSP0000042797597.610395.6801pteropus_vampyrusENSPVAP0000000208897.610395.6801
ENSG00000204764homo_sapiensENSP0000042797597.794195.4044myotis_lucifugusENSMLUP0000000519597.614795.2294
ENSG00000204764homo_sapiensENSP0000042797596.139790.625vombatus_ursinusENSVURP0001000196896.139790.625
ENSG00000204764homo_sapiensENSP0000042797598.161895.9559rhinolophus_ferrumequinumENSRFEP0001000867798.161895.9559
ENSG00000204764homo_sapiensENSP0000042797597.88695.864neovison_visonENSNVIP0000002897397.976195.9522
ENSG00000204764homo_sapiensENSP0000042797592.830990.0735bos_taurusENSBTAP0000003442389.69887.0337
ENSG00000204764homo_sapiensENSP0000042797597.242693.5662heterocephalus_glaber_femaleENSHGLP0000002042594.128190.5694
ENSG00000204764homo_sapiensENSP0000042797599.264798.0699rhinopithecus_bietiENSRBIP0000003351899.264798.0699
ENSG00000204764homo_sapiensENSP0000042797597.702295.3125canis_lupus_dingoENSCAFP0002001072797.792195.4002
ENSG00000204764homo_sapiensENSP0000042797597.88695.864sciurus_vulgarisENSSVLP0000501900097.88695.864
ENSG00000204764homo_sapiensENSP0000042797595.86490.625phascolarctos_cinereusENSPCIP0000001786195.86490.625
ENSG00000204764homo_sapiensENSP0000042797586.764783.1801procavia_capensisENSPCAP0000000480289.393985.7008
ENSG00000204764homo_sapiensENSP0000042797595.955992.739nannospalax_galiliENSNGAP0000001235296.48893.2532
ENSG00000204764homo_sapiensENSP0000042797597.334694.9449bos_grunniensENSBGRP0000002800597.334694.9449
ENSG00000204764homo_sapiensENSP0000042797597.794194.4853chinchilla_lanigeraENSCLAP0000001924297.794194.4853
ENSG00000204764homo_sapiensENSP0000042797597.610395.4044cervus_hanglu_yarkandensisENSCHYP0000002585496.021793.8517
ENSG00000204764homo_sapiensENSP0000042797598.621395.9559catagonus_wagneriENSCWAP0000000142598.621395.9559
ENSG00000204764homo_sapiensENSP0000042797597.977995.9559ictidomys_tridecemlineatusENSSTOP0000001318098.158496.1326
ENSG00000204764homo_sapiensENSP0000042797596.139793.8419otolemur_garnettiiENSOGAP0000001219496.051493.7557
ENSG00000204764homo_sapiensENSP0000042797598.713296.7831cebus_imitatorENSCCAP0000000817998.713296.7831
ENSG00000204764homo_sapiensENSP0000042797598.345696.4154urocitellus_parryiiENSUPAP0001002805998.345696.4154
ENSG00000204764homo_sapiensENSP0000042797597.334694.4853moschus_moschiferusENSMMSP0000002321697.513894.6593
ENSG00000204764homo_sapiensENSP0000042797599.172897.9779rhinopithecus_roxellanaENSRROP0000004442099.355498.1584
ENSG00000204764homo_sapiensENSP0000042797596.966992.9228mus_pahariMGP_PahariEiJ_P003289096.966992.9228
ENSG00000204764homo_sapiensENSP0000042797551.102948.989propithecus_coquereliENSPCOP0000000262095.205591.2671
ENSG00000204764homo_sapiensENSP0000042797560.110339.9816caenorhabditis_elegansC35A5.8.159.671539.6898
ENSG00000204764homo_sapiensENSP0000042797571.966954.0441drosophila_melanogasterFBpp029266470.540552.973
ENSG00000204764homo_sapiensENSP0000042797543.566231.3419ciona_intestinalisENSCINP0000001097871.171251.2012
ENSG00000204764homo_sapiensENSP0000042797587.775776.5625latimeria_chalumnaeENSLACP0000001360186.976375.8652
ENSG00000204764homo_sapiensENSP0000042797594.76188.8787chrysemys_picta_belliiENSCPBP0000003012294.67488.7971
ENSG00000204764homo_sapiensENSP0000042797593.198586.6728sphenodon_punctatusENSSPUP0000002253392.942386.4345
ENSG00000204764homo_sapiensENSP0000042797593.198587.1324crocodylus_porosusENSCPRP0000500435295.570289.3497
ENSG00000204764homo_sapiensENSP0000042797523.345620.3125laticauda_laticaudataENSLLTP0000000795959.484851.7564
ENSG00000204764homo_sapiensENSP0000042797539.797836.5809laticauda_laticaudataENSLLTP0000001499889.462882.2314
ENSG00000204764homo_sapiensENSP0000042797593.198586.0294notechis_scutatusENSNSUP0000000102593.370286.1878
ENSG00000204764homo_sapiensENSP0000042797591.63684.4669pseudonaja_textilisENSPTXP0000000791691.974284.7786
ENSG00000204764homo_sapiensENSP0000042797593.841987.2243anas_platyrhynchos_platyrhynchosENSAPLP0000001036093.841987.2243
ENSG00000204764homo_sapiensENSP0000042797549.356642.9228gallus_gallusENSGALP0001001420281.363670.7576
ENSG00000204764homo_sapiensENSP0000042797532.812528.2169meleagris_gallopavoENSMGAP0000000131885.817373.7981
ENSG00000204764homo_sapiensENSP0000042797585.477979.5956anolis_carolinensisENSACAP0000001531893.655687.2105
ENSG00000204764homo_sapiensENSP0000042797593.198586.2132naja_najaENSNNAP0000002322193.80286.7715
ENSG00000204764homo_sapiensENSP0000042797594.025787.7757podarcis_muralisENSPMRP0000000081893.939487.6951
ENSG00000204764homo_sapiensENSP0000042797593.7586.8566salvator_merianaeENSSMRP0000002955793.7586.8566
ENSG00000204764homo_sapiensENSP0000042797594.76189.0625gopherus_evgoodeiENSGEVP0000500577294.76189.0625
ENSG00000204764homo_sapiensENSP0000042797548.98946.0478chelonoidis_abingdoniiENSCABP0000000833495.178689.4643
ENSG00000204764homo_sapiensENSP0000042797519.669118.2904chelonoidis_abingdoniiENSCABP0000000833393.859687.2807
ENSG00000204764homo_sapiensENSP0000042797593.841987.2243struthio_camelus_australisENSSCUP0000000607193.755787.1442
ENSG00000204764homo_sapiensENSP0000042797593.198586.489anser_brachyrhynchusENSABRP0000002550092.942386.2511
ENSG00000204764homo_sapiensENSP0000042797593.382486.3971strigops_habroptilaENSSHBP0000501658692.955286.0018
ENSG00000204764homo_sapiensENSP0000042797592.922887.2243terrapene_carolina_triunguisENSTMTP0000002761195.287589.4439
ENSG00000204764homo_sapiensENSP0000042797572.058852.6654ciona_savignyiENSCSAVP0000001668870.886151.8083
ENSG00000204764homo_sapiensENSP0000042797594.301587.8676aquila_chrysaetos_chrysaetosENSACCP0002001888094.301587.8676

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0005049enables nuclear export signal receptor activity1IBAHomo_sapiens(9606)Function
GO:0005525enables GTP binding1NASHomo_sapiens(9606)Function
GO:0005643part_of nuclear pore2IBA,NASHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0006606involved_in protein import into nucleus1NASHomo_sapiens(9606)Process
GO:0006611involved_in protein export from nucleus1IBAHomo_sapiens(9606)Process
GO:0031267enables small GTPase binding1IEAHomo_sapiens(9606)Function
GO:0051028involved_in mRNA transport1IEAHomo_sapiens(9606)Process

Expression