RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	E3 ligase
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000204610	Gene ID	89870	Accession	16284
Symbol	TRIM15	Alias	RNF93;ZNFB7;ZNF178	Full Name	tripartite motif containing 15
Status	Confidence	Length	9488 bases	Strand	Plus strand
Position	6 : 30163206 - 30172693	RNA binding domain	SPRY
Summary	The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000484001	SPRY	PF00622	7.1e-11	1
ENSP00000365884	SPRY	PF00622	1.1e-10	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
12601	Psoriasis	1.675E-17	19680446
12919	Multiple Sclerosis	1.3E-5	19010793
12927	Multiple Sclerosis	1.7E-7	19010793
52144	Child Development Disorders, Pervasive	2.7000000E-005	-
52150	Child Development Disorders, Pervasive	2.4000000E-005	-
52163	Child Development Disorders, Pervasive	2.9000000E-005	-
52164	Child Development Disorders, Pervasive	3.3000000E-005	-
52176	Child Development Disorders, Pervasive	7.3600000E-006	-
52180	Child Development Disorders, Pervasive	2.9000000E-005	-
52195	Child Development Disorders, Pervasive	7.8500000E-006	-
52197	Child Development Disorders, Pervasive	3.3000000E-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003713	enables transcription coactivator activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005925	located_in focal adhesion	1	IEA	Homo_sapiens(9606)	Component
GO:0007500	involved_in mesodermal cell fate determination	1	TAS	Homo_sapiens(9606)	Process
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0016567	involved_in protein ubiquitination	1	IBA	Homo_sapiens(9606)	Process
GO:0032481	involved_in positive regulation of type I interferon production	1	IMP	Homo_sapiens(9606)	Process
GO:0044790	involved_in suppression of viral release by host	2	IDA,IMP	Homo_sapiens(9606)	Process
GO:0045087	involved_in innate immune response	1	IMP	Homo_sapiens(9606)	Process
GO:0045893	involved_in positive regulation of DNA-templated transcription	1	IEA	Homo_sapiens(9606)	Process
GO:0051091	involved_in positive regulation of DNA-binding transcription factor activity	1	IMP	Homo_sapiens(9606)	Process
GO:0051092	involved_in positive regulation of NF-kappaB transcription factor activity	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0140313	enables molecular sequestering activity	1	IDA	Homo_sapiens(9606)	Function
GO:1900246	involved_in positive regulation of RIG-I signaling pathway	1	IMP	Homo_sapiens(9606)	Process
GO:1901223	involved_in negative regulation of NIK/NF-kappaB signaling	1	IDA	Homo_sapiens(9606)	Process
GO:1901253	involved_in negative regulation of intracellular transport of viral material	1	IMP	Homo_sapiens(9606)	Process