RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	TF
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000204604	Gene ID	90333	Accession	33105
Symbol	ZNF468	Alias	NA	Full Name	zinc finger protein 468
Status	Confidence	Length	19640 bases	Strand	Minus strand
Position	19 : 52838010 - 52857649	RNA binding domain	zf-met
Summary	Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000470381	zf-met	PF12874	4.6e-10	1
ENSP00000470381	zf-met	PF12874	4.6e-10	2
ENSP00000470381	zf-met	PF12874	4.6e-10	3

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
ZNF468-202	ENST00000595646	4405	522aa	ENSP00000470381
ZNF468-201	ENST00000243639	4027	127aa	ENSP00000243639
ZNF468-203	ENST00000597924	533	137aa	ENSP00000469779
ZNF468-204	ENST00000601847	646	45aa	ENSP00000470717
ZNF468-206	ENST00000602144	571	77aa	ENSP00000471675
ZNF468-205	ENST00000601980	578	45aa	ENSP00000469733

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
72802	Alzheimer Disease	5E-6	22005930
72803	Depression	5E-6	22005930

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000204604	homo_sapiens	ENSP00000375662	81.2903	72.043	homo_sapiens	ENSP00000470381	72.4138	64.1762
ENSG00000204604	homo_sapiens	ENSP00000491567	59.3315	54.039	homo_sapiens	ENSP00000470381	81.6092	74.3295
ENSG00000204604	homo_sapiens	ENSP00000379689	78.3939	68.6424	homo_sapiens	ENSP00000470381	78.5441	68.7739
ENSG00000204604	homo_sapiens	ENSP00000379684	70.0162	61.9125	homo_sapiens	ENSP00000470381	82.7586	73.1801
ENSG00000204604	homo_sapiens	ENSP00000417696	78.7056	70.9812	homo_sapiens	ENSP00000470381	72.2222	65.1341
ENSG00000204604	homo_sapiens	ENSP00000507666	54.0214	48.3914	homo_sapiens	ENSP00000470381	77.2031	69.1571
ENSG00000204604	homo_sapiens	ENSP00000459216	70.339	61.1864	homo_sapiens	ENSP00000470381	79.5019	69.1571
ENSG00000204604	homo_sapiens	ENSP00000506273	63.4945	55.2262	homo_sapiens	ENSP00000470381	77.9693	67.8161
ENSG00000204604	homo_sapiens	ENSP00000373274	65.6646	57.2785	homo_sapiens	ENSP00000470381	79.5019	69.3487
ENSG00000204604	homo_sapiens	ENSP00000403266	58.679	50.9985	homo_sapiens	ENSP00000470381	73.1801	63.6015
ENSG00000204604	homo_sapiens	ENSP00000409652	66.0256	53.2051	homo_sapiens	ENSP00000470381	59.1954	47.7011

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000204604	homo_sapiens	ENSP00000470381	96.5517	95.5939	nomascus_leucogenys	ENSNLEP00000033663	96.5517	95.5939
ENSG00000204604	homo_sapiens	ENSP00000470381	81.6092	79.6935	pan_paniscus	ENSPPAP00000038554	94.0397	91.8322
ENSG00000204604	homo_sapiens	ENSP00000470381	95.5939	94.636	pongo_abelii	ENSPPYP00000011596	96.1464	95.183
ENSG00000204604	homo_sapiens	ENSP00000470381	97.8927	97.5096	pan_troglodytes	ENSPTRP00000040224	97.8927	97.5096
ENSG00000204604	homo_sapiens	ENSP00000470381	95.0192	92.9119	cercocebus_atys	ENSCATP00000036650	94.8375	92.7342
ENSG00000204604	homo_sapiens	ENSP00000470381	94.0613	91.7625	macaca_nemestrina	ENSMNEP00000036122	94.7876	92.471
ENSG00000204604	homo_sapiens	ENSP00000470381	94.636	92.9119	mandrillus_leucophaeus	ENSMLEP00000018076	94.4551	92.7342
ENSG00000204604	homo_sapiens	ENSP00000470381	14.751	12.2605	panthera_leo	ENSPLOP00000022593	73.3333	60.9524
ENSG00000204604	homo_sapiens	ENSP00000470381	13.2184	11.3027	oryctolagus_cuniculus	ENSOCUP00000026668	65.0943	55.6604
ENSG00000204604	homo_sapiens	ENSP00000470381	14.1762	11.3027	canis_lupus_familiaris	ENSCAFP00845006526	71.8447	57.2816
ENSG00000204604	homo_sapiens	ENSP00000470381	13.9847	12.069	felis_catus	ENSFCAP00000041606	68.8679	59.434
ENSG00000204604	homo_sapiens	ENSP00000470381	15.7088	13.7931	microcebus_murinus	ENSMICP00000041808	77.3585	67.9245
ENSG00000204604	homo_sapiens	ENSP00000470381	94.0613	91.954	chlorocebus_sabaeus	ENSCSAP00000016077	94.971	92.8433
ENSG00000204604	homo_sapiens	ENSP00000470381	13.7931	11.1111	phocoena_sinus	ENSPSNP00000018250	67.9245	54.717
ENSG00000204604	homo_sapiens	ENSP00000470381	15.9004	14.1762	prolemur_simus	ENSPSMP00000035428	78.3019	69.8113
ENSG00000204604	homo_sapiens	ENSP00000470381	13.7931	9.00383	bos_mutus	ENSBMUP00000004421	52.9412	34.5588
ENSG00000204604	homo_sapiens	ENSP00000470381	63.9847	48.4674	bos_mutus	ENSBMUP00000019023	54.4861	41.2724
ENSG00000204604	homo_sapiens	ENSP00000470381	14.3678	11.3027	neovison_vison	ENSNVIP00000030325	71.4286	56.1905
ENSG00000204604	homo_sapiens	ENSP00000470381	93.8697	91.3793	rhinopithecus_bieti	ENSRBIP00000026546	93.8697	91.3793
ENSG00000204604	homo_sapiens	ENSP00000470381	13.2184	10.9195	sciurus_vulgaris	ENSSVLP00005027028	66.9903	55.3398
ENSG00000204604	homo_sapiens	ENSP00000470381	64.1762	49.0421	cervus_hanglu_yarkandensis	ENSCHYP00000018715	54.3831	41.5584
ENSG00000204604	homo_sapiens	ENSP00000470381	59.1954	47.5096	catagonus_wagneri	ENSCWAP00000005747	50.2439	40.3252
ENSG00000204604	homo_sapiens	ENSP00000470381	93.8697	91.1877	rhinopithecus_roxellana	ENSRROP00000013909	93.8697	91.1877
ENSG00000204604	homo_sapiens	ENSP00000470381	63.7931	51.7241	propithecus_coquereli	ENSPCOP00000019640	71.0021	57.5693
ENSG00000204604	homo_sapiens	ENSP00000470381	15.9004	13.7931	propithecus_coquereli	ENSPCOP00000026624	78.3019	67.9245

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000978	enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0000981	enables DNA-binding transcription factor activity, RNA polymerase II-specific	1	IBA	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IBA	Homo_sapiens(9606)	Component
GO:0006357	involved_in regulation of transcription by RNA polymerase II	1	IBA	Homo_sapiens(9606)	Process
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function